# Ribocentre Aptamer Colored Structure Annotation
# version: 2
# slug: bacteriophage-MS2-coat-protein-aptamer
# title: Bacteriophage MS2 coat protein aptamer
# annotation.color_ranges (columns: chain,start,end,r,g,b)
# A,1,129,8,69,149
# R,1,6,46,161,3
# R,7,9,241,125,7
# R,10,14,46,161,3
# annotation.color_residues (columns: chain,residue,r,g,b)
# A,1,8,69,149
# A,2,8,69,149
# A,3,8,69,149
# A,4,8,69,149
# A,5,8,69,149
# A,6,8,69,149
# A,7,8,69,149
# A,8,8,69,149
# A,9,8,69,149
# A,10,8,69,149
# A,11,8,69,149
# A,12,8,69,149
# A,13,8,69,149
# A,14,8,69,149
# A,15,8,69,149
# A,16,8,69,149
# A,17,8,69,149
# A,18,8,69,149
# A,19,8,69,149
# A,20,8,69,149
# A,21,8,69,149
# A,22,8,69,149
# A,23,8,69,149
# A,24,8,69,149
# A,25,8,69,149
# A,26,8,69,149
# A,27,8,69,149
# A,28,8,69,149
# A,29,8,69,149
# A,30,8,69,149
# A,31,8,69,149
# A,32,8,69,149
# A,33,8,69,149
# A,34,8,69,149
# A,35,8,69,149
# A,36,8,69,149
# A,37,8,69,149
# A,38,8,69,149
# A,39,8,69,149
# A,40,8,69,149
# A,41,8,69,149
# A,42,8,69,149
# A,43,8,69,149
# A,44,8,69,149
# A,45,8,69,149
# A,46,8,69,149
# A,47,8,69,149
# A,48,8,69,149
# A,49,8,69,149
# A,50,8,69,149
# A,51,8,69,149
# A,52,8,69,149
# A,53,8,69,149
# A,54,8,69,149
# A,55,8,69,149
# A,56,8,69,149
# A,57,8,69,149
# A,58,8,69,149
# A,59,8,69,149
# A,60,8,69,149
# A,61,8,69,149
# A,62,8,69,149
# A,63,8,69,149
# A,64,8,69,149
# A,65,8,69,149
# A,66,8,69,149
# A,67,8,69,149
# A,68,8,69,149
# A,69,8,69,149
# A,70,8,69,149
# A,71,8,69,149
# A,72,8,69,149
# A,73,8,69,149
# A,74,8,69,149
# A,75,8,69,149
# A,76,8,69,149
# A,77,8,69,149
# A,78,8,69,149
# A,79,8,69,149
# A,80,8,69,149
# A,81,8,69,149
# A,82,8,69,149
# A,83,8,69,149
# A,84,8,69,149
# A,85,8,69,149
# A,86,8,69,149
# A,87,8,69,149
# A,88,8,69,149
# A,89,8,69,149
# A,90,8,69,149
# A,91,8,69,149
# A,92,8,69,149
# A,93,8,69,149
# A,94,8,69,149
# A,95,8,69,149
# A,96,8,69,149
# A,97,8,69,149
# A,98,8,69,149
# A,99,8,69,149
# A,100,8,69,149
# A,101,8,69,149
# A,102,8,69,149
# A,103,8,69,149
# A,104,8,69,149
# A,105,8,69,149
# A,106,8,69,149
# A,107,8,69,149
# A,108,8,69,149
# A,109,8,69,149
# A,110,8,69,149
# A,111,8,69,149
# A,112,8,69,149
# A,113,8,69,149
# A,114,8,69,149
# A,115,8,69,149
# A,116,8,69,149
# A,117,8,69,149
# A,118,8,69,149
# A,119,8,69,149
# A,120,8,69,149
# A,121,8,69,149
# A,122,8,69,149
# A,123,8,69,149
# A,124,8,69,149
# A,125,8,69,149
# A,126,8,69,149
# A,127,8,69,149
# A,128,8,69,149
# A,129,8,69,149
# R,1,46,161,3
# R,2,46,161,3
# R,3,46,161,3
# R,4,46,161,3
# R,5,46,161,3
# R,6,46,161,3
# R,7,241,125,7
# R,8,241,125,7
# R,9,241,125,7
# R,10,46,161,3
# R,11,46,161,3
# R,12,46,161,3
# R,13,46,161,3
# R,14,46,161,3
# end_annotation
data_6MSF
# 
_entry.id   6MSF 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.375 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   6MSF         pdb_00006msf 10.2210/pdb6msf/pdb 
RCSB  PRV010       ?            ?                   
WWPDB D_1000179844 ?            ?                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.entry_id                        6MSF 
_pdbx_database_status.recvd_initial_deposition_date   1998-01-06 
_pdbx_database_status.deposit_site                    BNL 
_pdbx_database_status.process_site                    NDB 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.SG_entry                        ? 
_pdbx_database_status.pdb_format_compatible           Y 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
'Convery, M.A.'    1 
'Rowsell, S.'      2 
'Stonehouse, N.J.' 3 
'Ellington, A.D.'  4 
'Hirao, I.'        5 
'Murray, J.B.'     6 
'Peabody, D.S.'    7 
'Phillips, S.E.V.' 8 
'Stockley, P.G.'   9 
# 
loop_
_citation.id 
_citation.title 
_citation.journal_abbrev 
_citation.journal_volume 
_citation.page_first 
_citation.page_last 
_citation.year 
_citation.journal_id_ASTM 
_citation.country 
_citation.journal_id_ISSN 
_citation.journal_id_CSD 
_citation.book_publisher 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_DOI 
primary 'Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution.' Nat.Struct.Biol. 5   133 139 1998 NSBIEW US 
1072-8368 2024 ? 9461079 10.1038/nsb0298-133 
1       
;The Three-Dimensional Structures of Two Complexes between Recombinant MS2 Capsids and RNA Operator Fragments Reveal Sequence-Specific Protein-RNA Interactions
;
J.Mol.Biol.      270 724 ?   1997 JMOBAK UK 0022-2836 0070 ? ?       ?                   
2       'Crystal Structure of an RNA Bacteriophage Coat Protein-Operator Complex' Nature           371 623 ?   1994 NATUAS UK 
0028-0836 0006 ? ?       ?                   
3       'The Refined Structure of Bacteriophage MS2 at 2.8 A Resolution' J.Mol.Biol.      234 620 ?   1993 JMOBAK UK 0022-2836 
0070 ? ?       ?                   
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Convery, M.A.'    1  ? 
primary 'Rowsell, S.'      2  ? 
primary 'Stonehouse, N.J.' 3  ? 
primary 'Ellington, A.D.'  4  ? 
primary 'Hirao, I.'        5  ? 
primary 'Murray, J.B.'     6  ? 
primary 'Peabody, D.S.'    7  ? 
primary 'Phillips, S.E.'   8  ? 
primary 'Stockley, P.G.'   9  ? 
1       'Valegard, K.'     10 ? 
1       'Murray, J.B.'     11 ? 
1       'Stonehouse, N.J.' 12 ? 
1       'Van Den Worm, S.' 13 ? 
1       'Stockley, P.G.'   14 ? 
1       'Liljas, L.'       15 ? 
2       'Valegard, K.'     16 ? 
2       'Murray, J.B.'     17 ? 
2       'Stockley, P.G.'   18 ? 
2       'Stonehouse, N.J.' 19 ? 
2       'Liljas, L.'       20 ? 
3       'Golmohammadi, R.' 21 ? 
3       'Valegard, K.'     22 ? 
3       'Fridborg, K.'     23 ? 
3       'Liljas, L.'       24 ? 
# 
_cell.entry_id           6MSF 
_cell.length_a           287.580 
_cell.length_b           287.580 
_cell.length_c           652.190 
_cell.angle_alpha        90.00 
_cell.angle_beta         90.00 
_cell.angle_gamma        120.00 
_cell.Z_PDB              540 
_cell.pdbx_unique_axis   ? 
# 
_symmetry.entry_id                         6MSF 
_symmetry.space_group_name_H-M             'H 3 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                155 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer syn 
;RNA (5'-R(*CP*CP*AP*CP*AP*GP*UP*CP*AP*CP*UP*GP*GP*G)-3')
;
4461.724  1  ? ? ? 'FAMILY 6 CONSENSUS SEQUENCE FROM IN VITRO SELECTION' 
2 polymer syn 
;RNA (5'-R(*CP*AP*GP*UP*CP*AP*CP*UP*GP*G)-3')
;
3176.948  1  ? ? ? 'FAMILY 6 CONSENSUS SEQUENCE FROM IN VITRO SELECTION' 
3 polymer man 'PROTEIN (MS2 PROTEIN CAPSID)'                             13738.464 3  ? ? ? ? 
4 water   nat water                                                      18.015    86 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 F6                 
2 F6                 
3 'MS2 COAT PROTEIN' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polyribonucleotide no no CCACAGUCACUGGG CCACAGUCACUGGG R     ? 
2 polyribonucleotide no no CAGUCACUGG CAGUCACUGG S     ? 
3 'polypeptide(L)'   no no 
;ASNFTQFVLVDNGGTGDVTVAPSNFANGVAEWISSNSRSQAYKVTCSVRQSSAQNRKYTIKVEVPKVATQTVGGVELPVA
AWRSYLNMELTIPIFATNSDCELIVKAMQGLLKDGNPIPSAIAANSGIY
;
;ASNFTQFVLVDNGGTGDVTVAPSNFANGVAEWISSNSRSQAYKVTCSVRQSSAQNRKYTIKVEVPKVATQTVGGVELPVA
AWRSYLNMELTIPIFATNSDCELIVKAMQGLLKDGNPIPSAIAANSGIY
;
A,B,C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   C   n 
1 2   C   n 
1 3   A   n 
1 4   C   n 
1 5   A   n 
1 6   G   n 
1 7   U   n 
1 8   C   n 
1 9   A   n 
1 10  C   n 
1 11  U   n 
1 12  G   n 
1 13  G   n 
1 14  G   n 
2 1   C   n 
2 2   A   n 
2 3   G   n 
2 4   U   n 
2 5   C   n 
2 6   A   n 
2 7   C   n 
2 8   U   n 
2 9   G   n 
2 10  G   n 
3 1   ALA n 
3 2   SER n 
3 3   ASN n 
3 4   PHE n 
3 5   THR n 
3 6   GLN n 
3 7   PHE n 
3 8   VAL n 
3 9   LEU n 
3 10  VAL n 
3 11  ASP n 
3 12  ASN n 
3 13  GLY n 
3 14  GLY n 
3 15  THR n 
3 16  GLY n 
3 17  ASP n 
3 18  VAL n 
3 19  THR n 
3 20  VAL n 
3 21  ALA n 
3 22  PRO n 
3 23  SER n 
3 24  ASN n 
3 25  PHE n 
3 26  ALA n 
3 27  ASN n 
3 28  GLY n 
3 29  VAL n 
3 30  ALA n 
3 31  GLU n 
3 32  TRP n 
3 33  ILE n 
3 34  SER n 
3 35  SER n 
3 36  ASN n 
3 37  SER n 
3 38  ARG n 
3 39  SER n 
3 40  GLN n 
3 41  ALA n 
3 42  TYR n 
3 43  LYS n 
3 44  VAL n 
3 45  THR n 
3 46  CYS n 
3 47  SER n 
3 48  VAL n 
3 49  ARG n 
3 50  GLN n 
3 51  SER n 
3 52  SER n 
3 53  ALA n 
3 54  GLN n 
3 55  ASN n 
3 56  ARG n 
3 57  LYS n 
3 58  TYR n 
3 59  THR n 
3 60  ILE n 
3 61  LYS n 
3 62  VAL n 
3 63  GLU n 
3 64  VAL n 
3 65  PRO n 
3 66  LYS n 
3 67  VAL n 
3 68  ALA n 
3 69  THR n 
3 70  GLN n 
3 71  THR n 
3 72  VAL n 
3 73  GLY n 
3 74  GLY n 
3 75  VAL n 
3 76  GLU n 
3 77  LEU n 
3 78  PRO n 
3 79  VAL n 
3 80  ALA n 
3 81  ALA n 
3 82  TRP n 
3 83  ARG n 
3 84  SER n 
3 85  TYR n 
3 86  LEU n 
3 87  ASN n 
3 88  MET n 
3 89  GLU n 
3 90  LEU n 
3 91  THR n 
3 92  ILE n 
3 93  PRO n 
3 94  ILE n 
3 95  PHE n 
3 96  ALA n 
3 97  THR n 
3 98  ASN n 
3 99  SER n 
3 100 ASP n 
3 101 CYS n 
3 102 GLU n 
3 103 LEU n 
3 104 ILE n 
3 105 VAL n 
3 106 LYS n 
3 107 ALA n 
3 108 MET n 
3 109 GLN n 
3 110 GLY n 
3 111 LEU n 
3 112 LEU n 
3 113 LYS n 
3 114 ASP n 
3 115 GLY n 
3 116 ASN n 
3 117 PRO n 
3 118 ILE n 
3 119 PRO n 
3 120 SER n 
3 121 ALA n 
3 122 ILE n 
3 123 ALA n 
3 124 ALA n 
3 125 ASN n 
3 126 SER n 
3 127 GLY n 
3 128 ILE n 
3 129 TYR n 
# 
_entity_src_gen.entity_id                          3 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      ? 
_entity_src_gen.pdbx_beg_seq_num                   ? 
_entity_src_gen.pdbx_end_seq_num                   ? 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     Levivirus 
_entity_src_gen.pdbx_gene_src_gene                 'COAT PROTEIN' 
_entity_src_gen.gene_src_species                   'Enterobacteria phage MS2' 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Enterobacterio phage MS2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     12022 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     Escherichia 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               TG1 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          PTAC 
_entity_src_gen.pdbx_host_org_vector               "PTACACP'" 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
1 UNP COAT_BPMS2 3 ? ? P03612 ? 
2 PDB 6MSF       1 ? ? 6MSF   ? 
3 PDB 6MSF       2 ? ? 6MSF   ? 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 6MSF A 1 ? 129 ? P03612 1 ? 129 ? 1 129 
2 1 6MSF B 1 ? 129 ? P03612 1 ? 129 ? 1 129 
3 1 6MSF C 1 ? 129 ? P03612 1 ? 129 ? 1 129 
4 2 6MSF R 1 ? 14  ? 6MSF   1 ? 14  ? 1 14  
5 3 6MSF S 1 ? 10  ? 6MSF   4 ? 13  ? 4 13  
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'  323.197 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'    121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'      75.067  
HOH non-polymer         . WATER                        ? 'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'  324.181 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'     117.146 
# 
_exptl.entry_id          6MSF 
_exptl.method            'X-RAY DIFFRACTION' 
_exptl.crystals_number   7 
# 
_exptl_crystal.id                    1 
_exptl_crystal.density_meas          ? 
_exptl_crystal.density_Matthews      ? 
_exptl_crystal.density_percent_sol   80.0000 
_exptl_crystal.description           'ADDITIONAL DATA WERE COLLECTED AT ESRF STATION ID2.' 
# 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.method          ? 
_exptl_crystal_grow.temp            ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.pH              7.4 
_exptl_crystal_grow.pdbx_details    
;PROTEIN IN 1.25% OR 1.5% PEG 8000, 0.1M NA PHOSPHATE PH 7.4 AND 0.02% NA AZIDE WAS EQUILIBRATED AGAINST 0.35M OR 0.4M NA PHOSPHATE PH 7.4, 0.02% NA AZIDE AT 30O OR 37O C. WASHED CRYSTALS WERE SOAKED IN 2MG/ML RNA.
;
_exptl_crystal_grow.pdbx_pH_range   ? 
# 
_diffrn.id                     1 
_diffrn.ambient_temp           278.00 
_diffrn.ambient_temp_details   ? 
_diffrn.crystal_id             1 
# 
_diffrn_detector.diffrn_id              1 
_diffrn_detector.detector               'IMAGE PLATE' 
_diffrn_detector.type                   MARRESEARCH 
_diffrn_detector.pdbx_collection_date   1997-06 
_diffrn_detector.details                MIRROR 
# 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.monochromator                    'SI(111)' 
_diffrn_radiation.pdbx_diffrn_protocol             ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   . 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.diffrn_id                   1 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.type                        'SRS BEAMLINE PX9.6' 
_diffrn_source.pdbx_synchrotron_site       SRS 
_diffrn_source.pdbx_synchrotron_beamline   PX9.6 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_wavelength_list        ? 
# 
_reflns.entry_id                     6MSF 
_reflns.observed_criterion_sigma_I   ? 
_reflns.observed_criterion_sigma_F   ? 
_reflns.d_resolution_low             36.000 
_reflns.d_resolution_high            2.800 
_reflns.number_obs                   169875 
_reflns.number_all                   ? 
_reflns.percent_possible_obs         68.000 
_reflns.pdbx_Rmerge_I_obs            0.186 
_reflns.pdbx_Rsym_value              ? 
_reflns.pdbx_netI_over_sigmaI        3.0 
_reflns.B_iso_Wilson_estimate        45.90 
_reflns.pdbx_redundancy              1.800 
_reflns.pdbx_diffrn_id               1 
_reflns.pdbx_ordinal                 1 
# 
_reflns_shell.d_res_high             2.800 
_reflns_shell.d_res_low              2.950 
_reflns_shell.percent_possible_all   43.00 
_reflns_shell.Rmerge_I_obs           0.369 
_reflns_shell.pdbx_Rsym_value        ? 
_reflns_shell.meanI_over_sigI_obs    ? 
_reflns_shell.pdbx_redundancy        1.300 
_reflns_shell.pdbx_diffrn_id         ? 
_reflns_shell.pdbx_ordinal           1 
# 
_refine.entry_id                                 6MSF 
_refine.ls_number_reflns_obs                     169871 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          0.000 
_refine.pdbx_data_cutoff_high_absF               1000000.000 
_refine.pdbx_data_cutoff_low_absF                0.0010 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             36.000 
_refine.ls_d_res_high                            2.800 
_refine.ls_percent_reflns_obs                    67.100 
_refine.ls_R_factor_obs                          0.195 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       0.195 
_refine.ls_R_factor_R_free                       0.201 
_refine.ls_R_factor_R_free_error                 0.002 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 4.000 
_refine.ls_number_reflns_R_free                  6829 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.B_iso_mean                               33.60 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.details                                  ? 
_refine.pdbx_starting_model                      'PDB ENTRY 2MS2' 
_refine.pdbx_method_to_determine_struct          'DIFFERENCE FOURIER' 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_B                             ? 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.pdbx_diffrn_id                           1 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
_refine_analyze.entry_id                        6MSF 
_refine_analyze.Luzzati_coordinate_error_obs    0.29 
_refine_analyze.Luzzati_sigma_a_obs             0.35 
_refine_analyze.Luzzati_d_res_low_obs           36.0 
_refine_analyze.Luzzati_coordinate_error_free   0.30 
_refine_analyze.Luzzati_sigma_a_free            0.33 
_refine_analyze.Luzzati_d_res_low_free          ? 
_refine_analyze.number_disordered_residues      ? 
_refine_analyze.occupancy_sum_hydrogen          ? 
_refine_analyze.occupancy_sum_non_hydrogen      ? 
_refine_analyze.pdbx_refine_id                  'X-RAY DIFFRACTION' 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        2904 
_refine_hist.pdbx_number_atoms_nucleic_acid   505 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.number_atoms_solvent             86 
_refine_hist.number_atoms_total               3495 
_refine_hist.d_res_high                       2.800 
_refine_hist.d_res_low                        36.000 
# 
loop_
_refine_ls_restr.type 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.weight 
_refine_ls_restr.number 
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.pdbx_restraint_function 
x_bond_d                0.007 ?     ? ? 'X-RAY DIFFRACTION' ? 
x_bond_d_na             ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_bond_d_prot           ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_angle_d               ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_angle_d_na            ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_angle_d_prot          ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_angle_deg             1.40  ?     ? ? 'X-RAY DIFFRACTION' ? 
x_angle_deg_na          ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_angle_deg_prot        ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_dihedral_angle_d      27.3  ?     ? ? 'X-RAY DIFFRACTION' ? 
x_dihedral_angle_d_na   ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_dihedral_angle_d_prot ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_improper_angle_d      0.95  ?     ? ? 'X-RAY DIFFRACTION' ? 
x_improper_angle_d_na   ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_improper_angle_d_prot ?     ?     ? ? 'X-RAY DIFFRACTION' ? 
x_mcbond_it             6.050 2.000 ? ? 'X-RAY DIFFRACTION' ? 
x_mcangle_it            8.060 2.500 ? ? 'X-RAY DIFFRACTION' ? 
x_scbond_it             9.980 2.500 ? ? 'X-RAY DIFFRACTION' ? 
x_scangle_it            12.09 3.000 ? ? 'X-RAY DIFFRACTION' ? 
# 
_refine_ls_restr_ncs.dom_id              1 
_refine_ls_restr_ncs.ncs_model_details   CONSTRAINED 
_refine_ls_restr_ncs.rms_dev_position    ? 
_refine_ls_restr_ncs.weight_position     ? 
_refine_ls_restr_ncs.rms_dev_B_iso       ? 
_refine_ls_restr_ncs.weight_B_iso        ? 
_refine_ls_restr_ncs.pdbx_type           . 
_refine_ls_restr_ncs.pdbx_auth_asym_id   . 
_refine_ls_restr_ncs.pdbx_ens_id         1 
_refine_ls_restr_ncs.pdbx_refine_id      'X-RAY DIFFRACTION' 
_refine_ls_restr_ncs.pdbx_ordinal        1 
_refine_ls_restr_ncs.pdbx_asym_id        . 
_refine_ls_restr_ncs.pdbx_number         ? 
_refine_ls_restr_ncs.pdbx_rms            ? 
_refine_ls_restr_ncs.pdbx_weight         ? 
# 
_refine_ls_shell.pdbx_total_number_of_bins_used   6 
_refine_ls_shell.d_res_high                       2.80 
_refine_ls_shell.d_res_low                        2.98 
_refine_ls_shell.number_reflns_R_work             17123 
_refine_ls_shell.R_factor_R_work                  0.303 
_refine_ls_shell.percent_reflns_obs               42.50 
_refine_ls_shell.R_factor_R_free                  0.295 
_refine_ls_shell.R_factor_R_free_error            0.01 
_refine_ls_shell.percent_reflns_R_free            3.90 
_refine_ls_shell.number_reflns_R_free             697 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.R_factor_all                     ? 
# 
loop_
_pdbx_xplor_file.serial_no 
_pdbx_xplor_file.param_file 
_pdbx_xplor_file.topol_file 
_pdbx_xplor_file.pdbx_refine_id 
1 PROTEIN_REP.PARAM TOPHCSDX.PRO 'X-RAY DIFFRACTION' 
2 DNA-RNA_REP.PARAM TOPH19.SOL   'X-RAY DIFFRACTION' 
3 ?                 DNA-RNA.TOP  'X-RAY DIFFRACTION' 
# 
loop_
_struct_ncs_oper.id 
_struct_ncs_oper.code 
_struct_ncs_oper.details 
_struct_ncs_oper.matrix[1][1] 
_struct_ncs_oper.matrix[1][2] 
_struct_ncs_oper.matrix[1][3] 
_struct_ncs_oper.matrix[2][1] 
_struct_ncs_oper.matrix[2][2] 
_struct_ncs_oper.matrix[2][3] 
_struct_ncs_oper.matrix[3][1] 
_struct_ncs_oper.matrix[3][2] 
_struct_ncs_oper.matrix[3][3] 
_struct_ncs_oper.vector[1] 
_struct_ncs_oper.vector[2] 
_struct_ncs_oper.vector[3] 
1  given    ? 1.00000000  0.00000000  0.00000000  0.00000000  1.00000000  0.00000000  0.00000000  0.00000000  1.00000000  0.00000 
0.00000 0.00000 
2  generate ? 0.50000000  -0.86602540 0.00000079  0.64549670  0.37267830  0.66666701  -0.57735086 -0.33333299 0.74535569  0.00000 
0.00000 0.00000 
3  generate ? -0.30901699 -0.75576184 -0.57734958 0.17841019  -0.64234953 0.74535688  -0.93417252 0.12732289  0.33333254  0.00000 
0.00000 0.00000 
4  generate ? -0.30901699 0.17841019  -0.93417252 -0.75576184 -0.64234953 0.12732289  -0.57734958 0.74535688  0.33333254  0.00000 
0.00000 0.00000 
5  generate ? 0.50000000  0.64549670  -0.57735086 -0.86602540 0.37267830  -0.33333299 0.00000079  0.66666701  0.74535569  0.00000 
0.00000 0.00000 
6  generate ? 0.30901699  -0.75576184 -0.57734958 -0.75576184 -0.56366040 0.33333317  -0.57734958 0.33333317  -0.74535660 0.00000 
0.00000 0.00000 
7  generate ? 0.00000000  -0.35682294 -0.93417203 -0.93417203 0.33333401  -0.12732261 0.35682294  0.87267739  -0.33333401 0.00000 
0.00000 0.00000 
8  generate ? 0.30901699  0.17841019  -0.93417252 -0.17841019 0.97568389  0.12732142  0.93417252  0.12732142  0.33333310  0.00000 
0.00000 0.00000 
9  generate ? 0.80901699  0.11026356  -0.57735037 0.46708650  0.47568355  0.74535586  0.35682166  -0.87267813 0.33333345  0.00000 
0.00000 0.00000 
10 generate ? 0.80901699  -0.46708650 -0.35682166 0.11026356  -0.47568355 0.87267813  -0.57735037 -0.74535586 -0.33333345 0.00000 
0.00000 0.00000 
# 
_struct_ncs_dom.id            1 
_struct_ncs_dom.pdbx_ens_id   1 
_struct_ncs_dom.details       ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   ? 
# 
_struct.entry_id                  6MSF 
_struct.title                     'F6 APTAMER MS2 COAT PROTEIN COMPLEX' 
_struct.pdbx_model_details        ? 
_struct.pdbx_CASP_flag            ? 
_struct.pdbx_model_type_details   ? 
# 
_struct_keywords.entry_id        6MSF 
_struct_keywords.pdbx_keywords   Virus/RNA 
_struct_keywords.text            
'VIRAL COAT PROTEIN-RNA COMPLEX, RNA APTAMER, RNA STEM LOOP, BACTERIOPHAGE MS2, Icosahedral virus, Virus-RNA COMPLEX' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
# 
_struct_biol.id                    1 
_struct_biol.details               
;THE COMPLETE PARTICLE CAN BE GENERATED BY APPLYING THE NCS
MATRICES TO THE COORDINATES AND THEN APPLYING THE
CRYSTALLOGRAPHIC SYMMETRY OPERATORS.
;
_struct_biol.pdbx_parent_biol_id   ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  1  ALA C 26  ? GLY C 28  ? ALA A 26  GLY A 28  5 ? 3  
HELX_P HELX_P2  2  ASN C 98  ? LEU C 111 ? ASN A 98  LEU A 111 1 ? 14 
HELX_P HELX_P3  3  PRO C 117 ? ALA C 124 ? PRO A 117 ALA A 124 1 ? 8  
HELX_P HELX_P4  4  ALA D 26  ? GLY D 28  ? ALA B 26  GLY B 28  5 ? 3  
HELX_P HELX_P5  5  VAL D 79  ? ALA D 81  ? VAL B 79  ALA B 81  5 ? 3  
HELX_P HELX_P6  6  ASN D 98  ? LEU D 111 ? ASN B 98  LEU B 111 1 ? 14 
HELX_P HELX_P7  7  PRO D 117 ? ALA D 124 ? PRO B 117 ALA B 124 1 ? 8  
HELX_P HELX_P8  8  ARG E 38  ? GLN E 40  ? ARG C 38  GLN C 40  5 ? 3  
HELX_P HELX_P9  9  ASN E 98  ? LEU E 112 ? ASN C 98  LEU C 112 1 ? 15 
HELX_P HELX_P10 10 PRO E 117 ? ALA E 124 ? PRO C 117 ALA C 124 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? A C 1 N3 ? ? ? 1_555 A G 14 N1 ? ? R C 1 R G 14 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog2  hydrog ? ? A C 1 N4 ? ? ? 1_555 A G 14 O6 ? ? R C 1 R G 14 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog3  hydrog ? ? A C 1 O2 ? ? ? 1_555 A G 14 N2 ? ? R C 1 R G 14 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog4  hydrog ? ? A C 2 N3 ? ? ? 1_555 A G 13 N1 ? ? R C 2 R G 13 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog5  hydrog ? ? A C 2 N4 ? ? ? 1_555 A G 13 O6 ? ? R C 2 R G 13 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog6  hydrog ? ? A C 2 O2 ? ? ? 1_555 A G 13 N2 ? ? R C 2 R G 13 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog7  hydrog ? ? A C 4 N3 ? ? ? 1_555 A G 12 N1 ? ? R C 4 R G 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog8  hydrog ? ? A C 4 N4 ? ? ? 1_555 A G 12 O6 ? ? R C 4 R G 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog9  hydrog ? ? A C 4 O2 ? ? ? 1_555 A G 12 N2 ? ? R C 4 R G 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog10 hydrog ? ? A A 5 N1 ? ? ? 1_555 A U 11 N3 ? ? R A 5 R U 11 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog11 hydrog ? ? A A 5 N6 ? ? ? 1_555 A U 11 O4 ? ? R A 5 R U 11 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog12 hydrog ? ? A G 6 N1 ? ? ? 1_555 A C 10 N3 ? ? R G 6 R C 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog13 hydrog ? ? A G 6 N2 ? ? ? 1_555 A C 10 O2 ? ? R G 6 R C 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog14 hydrog ? ? A G 6 O6 ? ? ? 1_555 A C 10 N4 ? ? R G 6 R C 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog15 hydrog ? ? B C 1 N3 ? ? ? 1_555 B G 9  N1 ? ? S C 4 S G 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog16 hydrog ? ? B C 1 N4 ? ? ? 1_555 B G 9  O6 ? ? S C 4 S G 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog17 hydrog ? ? B C 1 O2 ? ? ? 1_555 B G 9  N2 ? ? S C 4 S G 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog18 hydrog ? ? B A 2 N1 ? ? ? 1_555 B U 8  N3 ? ? S A 5 S U 11 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog19 hydrog ? ? B A 2 N6 ? ? ? 1_555 B U 8  O4 ? ? S A 5 S U 11 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog20 hydrog ? ? B G 3 N1 ? ? ? 1_555 B C 7  N3 ? ? S G 6 S C 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog21 hydrog ? ? B G 3 N2 ? ? ? 1_555 B C 7  O2 ? ? S G 6 S C 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog22 hydrog ? ? B G 3 O6 ? ? ? 1_555 B C 7  N4 ? ? S G 6 S C 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          LEU 
_struct_mon_prot_cis.label_seq_id           77 
_struct_mon_prot_cis.label_asym_id          D 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           LEU 
_struct_mon_prot_cis.auth_seq_id            77 
_struct_mon_prot_cis.auth_asym_id           B 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    78 
_struct_mon_prot_cis.pdbx_label_asym_id_2   D 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     78 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    B 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -0.29 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
A ? 6 ? 
B ? 5 ? 
C ? 2 ? 
D ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
A 1 2 ? anti-parallel 
A 2 3 ? anti-parallel 
A 3 4 ? anti-parallel 
A 4 5 ? anti-parallel 
A 5 6 ? anti-parallel 
B 1 2 ? anti-parallel 
B 2 3 ? anti-parallel 
B 3 4 ? anti-parallel 
B 4 5 ? anti-parallel 
C 1 2 ? anti-parallel 
D 1 2 ? anti-parallel 
D 2 3 ? anti-parallel 
D 3 4 ? anti-parallel 
D 4 5 ? anti-parallel 
D 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
A 1 VAL C 75 ? PRO C 93 ? VAL A 75 PRO A 93 
A 2 ASN C 55 ? VAL C 72 ? ASN A 55 VAL A 72 
A 3 LYS C 43 ? ARG C 49 ? LYS A 43 ARG A 49 
A 4 ALA C 30 ? SER C 34 ? ALA A 30 SER A 34 
A 5 VAL C 18 ? ASN C 24 ? VAL A 18 ASN A 24 
A 6 PHE C 7  ? VAL C 10 ? PHE A 7  VAL A 10 
B 1 ARG D 83 ? PRO D 93 ? ARG B 83 PRO B 93 
B 2 ASN D 55 ? PRO D 65 ? ASN B 55 PRO B 65 
B 3 LYS D 43 ? ARG D 49 ? LYS B 43 ARG B 49 
B 4 ALA D 30 ? ILE D 33 ? ALA B 30 ILE B 33 
B 5 ALA D 21 ? ASN D 24 ? ALA B 21 ASN B 24 
C 1 PHE D 7  ? VAL D 10 ? PHE B 7  VAL B 10 
C 2 VAL D 18 ? VAL D 20 ? VAL B 18 VAL B 20 
D 1 VAL E 75 ? PRO E 93 ? VAL C 75 PRO C 93 
D 2 ASN E 55 ? VAL E 72 ? ASN C 55 VAL C 72 
D 3 LYS E 43 ? GLN E 50 ? LYS C 43 GLN C 50 
D 4 VAL E 29 ? SER E 34 ? VAL C 29 SER C 34 
D 5 VAL E 18 ? ALA E 26 ? VAL C 18 ALA C 26 
D 6 PHE E 7  ? VAL E 10 ? PHE C 7  VAL C 10 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
A 1 2 O VAL C 75 ? O VAL A 75 N VAL C 72 ? N VAL A 72 
A 2 3 O LYS C 57 ? O LYS A 57 N ARG C 49 ? N ARG A 49 
A 3 4 O VAL C 44 ? O VAL A 44 N TRP C 32 ? N TRP A 32 
A 4 5 O GLU C 31 ? O GLU A 31 N ASN C 24 ? N ASN A 24 
A 5 6 O VAL C 18 ? O VAL A 18 N VAL C 10 ? N VAL A 10 
B 1 2 O SER D 84 ? O SER B 84 N VAL D 64 ? N VAL B 64 
B 2 3 O LYS D 57 ? O LYS B 57 N ARG D 49 ? N ARG B 49 
B 3 4 O VAL D 44 ? O VAL B 44 N TRP D 32 ? N TRP B 32 
B 4 5 O GLU D 31 ? O GLU B 31 N ASN D 24 ? N ASN B 24 
C 1 2 O PHE D 7  ? O PHE B 7  N VAL D 20 ? N VAL B 20 
D 1 2 O VAL E 75 ? O VAL C 75 N VAL E 72 ? N VAL C 72 
D 2 3 O LYS E 57 ? O LYS C 57 N ARG E 49 ? N ARG C 49 
D 3 4 O VAL E 44 ? O VAL C 44 N TRP E 32 ? N TRP C 32 
D 4 5 O VAL E 29 ? O VAL C 29 N ALA E 26 ? N ALA C 26 
D 5 6 O VAL E 18 ? O VAL C 18 N VAL E 10 ? N VAL C 10 
# 
_database_PDB_matrix.entry_id          6MSF 
_database_PDB_matrix.origx[1][1]       1.000000 
_database_PDB_matrix.origx[1][2]       0.000000 
_database_PDB_matrix.origx[1][3]       0.000000 
_database_PDB_matrix.origx[2][1]       0.000000 
_database_PDB_matrix.origx[2][2]       1.000000 
_database_PDB_matrix.origx[2][3]       0.000000 
_database_PDB_matrix.origx[3][1]       0.000000 
_database_PDB_matrix.origx[3][2]       0.000000 
_database_PDB_matrix.origx[3][3]       1.000000 
_database_PDB_matrix.origx_vector[1]   0.00000 
_database_PDB_matrix.origx_vector[2]   0.00000 
_database_PDB_matrix.origx_vector[3]   0.00000 
# 
_atom_sites.entry_id                    6MSF 
_atom_sites.fract_transf_matrix[1][1]   0.003477 
_atom_sites.fract_transf_matrix[1][2]   0.002008 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.004015 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.001533 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    O "O5'" . C   A 1 1   ? -61.159  50.685 72.507 0.70 90.74  ? 1   C   R "O5'" 1 
ATOM   2    C "C5'" . C   A 1 1   ? -60.577  51.092 73.752 0.70 91.46  ? 1   C   R "C5'" 1 
ATOM   3    C "C4'" . C   A 1 1   ? -59.080  51.294 73.670 0.70 90.36  ? 1   C   R "C4'" 1 
ATOM   4    O "O4'" . C   A 1 1   ? -58.496  50.244 72.855 0.70 84.96  ? 1   C   R "O4'" 1 
ATOM   5    C "C3'" . C   A 1 1   ? -58.626  52.582 73.002 0.70 86.98  ? 1   C   R "C3'" 1 
ATOM   6    O "O3'" . C   A 1 1   ? -58.613  53.666 73.921 0.70 82.51  ? 1   C   R "O3'" 1 
ATOM   7    C "C2'" . C   A 1 1   ? -57.225  52.225 72.524 0.70 81.41  ? 1   C   R "C2'" 1 
ATOM   8    O "O2'" . C   A 1 1   ? -56.252  52.299 73.547 0.70 72.87  ? 1   C   R "O2'" 1 
ATOM   9    C "C1'" . C   A 1 1   ? -57.419  50.770 72.095 0.70 79.69  ? 1   C   R "C1'" 1 
ATOM   10   N N1    . C   A 1 1   ? -57.762  50.644 70.672 0.70 81.00  ? 1   C   R N1    1 
ATOM   11   C C2    . C   A 1 1   ? -56.748  50.795 69.721 0.70 82.96  ? 1   C   R C2    1 
ATOM   12   O O2    . C   A 1 1   ? -55.590  51.040 70.107 0.70 76.75  ? 1   C   R O2    1 
ATOM   13   N N3    . C   A 1 1   ? -57.055  50.674 68.407 0.70 79.33  ? 1   C   R N3    1 
ATOM   14   C C4    . C   A 1 1   ? -58.311  50.422 68.033 0.70 78.46  ? 1   C   R C4    1 
ATOM   15   N N4    . C   A 1 1   ? -58.562  50.316 66.725 0.70 71.24  ? 1   C   R N4    1 
ATOM   16   C C5    . C   A 1 1   ? -59.363  50.267 68.982 0.70 78.49  ? 1   C   R C5    1 
ATOM   17   C C6    . C   A 1 1   ? -59.046  50.383 70.279 0.70 77.88  ? 1   C   R C6    1 
ATOM   18   P P     . C   A 1 2   ? -59.002  55.136 73.410 0.70 79.29  ? 2   C   R P     1 
ATOM   19   O OP1   . C   A 1 2   ? -59.106  56.032 74.593 0.70 70.71  ? 2   C   R OP1   1 
ATOM   20   O OP2   . C   A 1 2   ? -60.168  54.978 72.502 0.70 65.72  ? 2   C   R OP2   1 
ATOM   21   O "O5'" . C   A 1 2   ? -57.741  55.579 72.542 0.70 71.84  ? 2   C   R "O5'" 1 
ATOM   22   C "C5'" . C   A 1 2   ? -56.473  55.785 73.156 0.70 60.77  ? 2   C   R "C5'" 1 
ATOM   23   C "C4'" . C   A 1 2   ? -55.448  56.207 72.128 0.70 60.25  ? 2   C   R "C4'" 1 
ATOM   24   O "O4'" . C   A 1 2   ? -55.222  55.110 71.203 0.70 65.22  ? 2   C   R "O4'" 1 
ATOM   25   C "C3'" . C   A 1 2   ? -55.876  57.356 71.228 0.70 63.28  ? 2   C   R "C3'" 1 
ATOM   26   O "O3'" . C   A 1 2   ? -55.603  58.607 71.842 0.70 65.10  ? 2   C   R "O3'" 1 
ATOM   27   C "C2'" . C   A 1 2   ? -54.999  57.151 70.000 0.70 60.07  ? 2   C   R "C2'" 1 
ATOM   28   O "O2'" . C   A 1 2   ? -53.689  57.651 70.180 0.70 51.39  ? 2   C   R "O2'" 1 
ATOM   29   C "C1'" . C   A 1 2   ? -54.956  55.625 69.910 0.70 56.70  ? 2   C   R "C1'" 1 
ATOM   30   N N1    . C   A 1 2   ? -55.918  55.053 68.957 0.70 54.46  ? 2   C   R N1    1 
ATOM   31   C C2    . C   A 1 2   ? -55.518  54.902 67.627 0.70 54.50  ? 2   C   R C2    1 
ATOM   32   O O2    . C   A 1 2   ? -54.375  55.257 67.305 0.70 56.45  ? 2   C   R O2    1 
ATOM   33   N N3    . C   A 1 2   ? -56.382  54.376 66.729 0.70 48.55  ? 2   C   R N3    1 
ATOM   34   C C4    . C   A 1 2   ? -57.604  54.011 67.116 0.70 50.86  ? 2   C   R C4    1 
ATOM   35   N N4    . C   A 1 2   ? -58.420  53.496 66.189 0.70 49.10  ? 2   C   R N4    1 
ATOM   36   C C5    . C   A 1 2   ? -58.043  54.157 68.468 0.70 51.12  ? 2   C   R C5    1 
ATOM   37   C C6    . C   A 1 2   ? -57.174  54.678 69.347 0.70 48.51  ? 2   C   R C6    1 
ATOM   38   P P     . A   A 1 3   ? -56.781  59.391 72.597 0.70 60.27  ? 3   A   R P     1 
ATOM   39   O OP1   . A   A 1 3   ? -56.696  59.035 74.038 0.70 51.72  ? 3   A   R OP1   1 
ATOM   40   O OP2   . A   A 1 3   ? -58.048  59.168 71.851 0.70 49.48  ? 3   A   R OP2   1 
ATOM   41   O "O5'" . A   A 1 3   ? -56.388  60.925 72.463 0.70 55.29  ? 3   A   R "O5'" 1 
ATOM   42   C "C5'" . A   A 1 3   ? -56.395  61.612 71.209 0.70 51.82  ? 3   A   R "C5'" 1 
ATOM   43   C "C4'" . A   A 1 3   ? -55.471  62.788 71.322 0.70 42.82  ? 3   A   R "C4'" 1 
ATOM   44   O "O4'" . A   A 1 3   ? -55.879  63.551 72.476 0.70 46.44  ? 3   A   R "O4'" 1 
ATOM   45   C "C3'" . A   A 1 3   ? -54.013  62.443 71.550 0.70 49.47  ? 3   A   R "C3'" 1 
ATOM   46   O "O3'" . A   A 1 3   ? -53.380  62.356 70.271 0.70 57.33  ? 3   A   R "O3'" 1 
ATOM   47   C "C2'" . A   A 1 3   ? -53.527  63.665 72.321 0.70 41.02  ? 3   A   R "C2'" 1 
ATOM   48   O "O2'" . A   A 1 3   ? -53.290  64.764 71.467 0.70 45.05  ? 3   A   R "O2'" 1 
ATOM   49   C "C1'" . A   A 1 3   ? -54.746  63.971 73.202 0.70 40.68  ? 3   A   R "C1'" 1 
ATOM   50   N N9    . A   A 1 3   ? -54.822  63.229 74.462 0.70 43.54  ? 3   A   R N9    1 
ATOM   51   C C8    . A   A 1 3   ? -54.071  62.167 74.905 0.70 42.51  ? 3   A   R C8    1 
ATOM   52   N N7    . A   A 1 3   ? -54.452  61.701 76.072 0.70 39.95  ? 3   A   R N7    1 
ATOM   53   C C5    . A   A 1 3   ? -55.519  62.517 76.427 0.70 38.45  ? 3   A   R C5    1 
ATOM   54   C C6    . A   A 1 3   ? -56.365  62.543 77.556 0.70 38.78  ? 3   A   R C6    1 
ATOM   55   N N6    . A   A 1 3   ? -56.261  61.691 78.580 0.70 31.60  ? 3   A   R N6    1 
ATOM   56   N N1    . A   A 1 3   ? -57.336  63.485 77.595 0.70 41.79  ? 3   A   R N1    1 
ATOM   57   C C2    . A   A 1 3   ? -57.441  64.339 76.569 0.70 33.91  ? 3   A   R C2    1 
ATOM   58   N N3    . A   A 1 3   ? -56.708  64.416 75.458 0.70 35.49  ? 3   A   R N3    1 
ATOM   59   C C4    . A   A 1 3   ? -55.752  63.467 75.449 0.70 39.20  ? 3   A   R C4    1 
ATOM   60   P P     . C   A 1 4   ? -52.814  60.944 69.741 0.70 54.46  ? 4   C   R P     1 
ATOM   61   O OP1   . C   A 1 4   ? -52.196  60.228 70.888 0.70 61.19  ? 4   C   R OP1   1 
ATOM   62   O OP2   . C   A 1 4   ? -52.004  61.232 68.532 0.70 54.19  ? 4   C   R OP2   1 
ATOM   63   O "O5'" . C   A 1 4   ? -54.096  60.116 69.273 0.70 54.44  ? 4   C   R "O5'" 1 
ATOM   64   C "C5'" . C   A 1 4   ? -54.954  60.595 68.237 0.70 51.23  ? 4   C   R "C5'" 1 
ATOM   65   C "C4'" . C   A 1 4   ? -54.309  60.386 66.885 0.70 47.71  ? 4   C   R "C4'" 1 
ATOM   66   O "O4'" . C   A 1 4   ? -54.355  58.974 66.533 0.70 47.48  ? 4   C   R "O4'" 1 
ATOM   67   C "C3'" . C   A 1 4   ? -55.034  61.058 65.731 0.70 44.20  ? 4   C   R "C3'" 1 
ATOM   68   O "O3'" . C   A 1 4   ? -54.700  62.428 65.607 0.70 42.70  ? 4   C   R "O3'" 1 
ATOM   69   C "C2'" . C   A 1 4   ? -54.573  60.244 64.533 0.70 41.91  ? 4   C   R "C2'" 1 
ATOM   70   O "O2'" . C   A 1 4   ? -53.293  60.613 64.062 0.70 37.38  ? 4   C   R "O2'" 1 
ATOM   71   C "C1'" . C   A 1 4   ? -54.532  58.840 65.130 0.70 41.31  ? 4   C   R "C1'" 1 
ATOM   72   N N1    . C   A 1 4   ? -55.788  58.125 64.867 0.70 37.78  ? 4   C   R N1    1 
ATOM   73   C C2    . C   A 1 4   ? -56.095  57.817 63.542 0.70 43.26  ? 4   C   R C2    1 
ATOM   74   O O2    . C   A 1 4   ? -55.298  58.155 62.657 0.70 53.06  ? 4   C   R O2    1 
ATOM   75   N N3    . C   A 1 4   ? -57.245  57.165 63.259 0.70 38.23  ? 4   C   R N3    1 
ATOM   76   C C4    . C   A 1 4   ? -58.073  56.819 64.243 0.70 38.98  ? 4   C   R C4    1 
ATOM   77   N N4    . C   A 1 4   ? -59.192  56.169 63.912 0.70 35.66  ? 4   C   R N4    1 
ATOM   78   C C5    . C   A 1 4   ? -57.787  57.122 65.611 0.70 35.69  ? 4   C   R C5    1 
ATOM   79   C C6    . C   A 1 4   ? -56.641  57.771 65.874 0.70 33.88  ? 4   C   R C6    1 
ATOM   80   P P     . A   A 1 5   ? -55.822  63.467 65.126 0.70 45.14  ? 5   A   R P     1 
ATOM   81   O OP1   . A   A 1 5   ? -55.257  64.831 65.293 0.70 37.57  ? 5   A   R OP1   1 
ATOM   82   O OP2   . A   A 1 5   ? -57.091  63.104 65.808 0.70 49.06  ? 5   A   R OP2   1 
ATOM   83   O "O5'" . A   A 1 5   ? -55.997  63.158 63.571 0.70 42.19  ? 5   A   R "O5'" 1 
ATOM   84   C "C5'" . A   A 1 5   ? -55.081  63.696 62.628 0.70 40.91  ? 5   A   R "C5'" 1 
ATOM   85   C "C4'" . A   A 1 5   ? -55.567  63.479 61.215 0.70 43.96  ? 5   A   R "C4'" 1 
ATOM   86   O "O4'" . A   A 1 5   ? -55.544  62.055 60.915 0.70 47.04  ? 5   A   R "O4'" 1 
ATOM   87   C "C3'" . A   A 1 5   ? -57.011  63.869 60.939 0.70 42.02  ? 5   A   R "C3'" 1 
ATOM   88   O "O3'" . A   A 1 5   ? -57.206  65.256 60.708 0.70 39.96  ? 5   A   R "O3'" 1 
ATOM   89   C "C2'" . A   A 1 5   ? -57.336  63.040 59.708 0.70 45.81  ? 5   A   R "C2'" 1 
ATOM   90   O "O2'" . A   A 1 5   ? -56.817  63.600 58.520 0.70 42.78  ? 5   A   R "O2'" 1 
ATOM   91   C "C1'" . A   A 1 5   ? -56.607  61.739 60.028 0.70 47.97  ? 5   A   R "C1'" 1 
ATOM   92   N N9    . A   A 1 5   ? -57.534  60.820 60.676 0.70 47.29  ? 5   A   R N9    1 
ATOM   93   C C8    . A   A 1 5   ? -57.700  60.501 62.000 0.70 47.48  ? 5   A   R C8    1 
ATOM   94   N N7    . A   A 1 5   ? -58.676  59.648 62.216 0.70 50.13  ? 5   A   R N7    1 
ATOM   95   C C5    . A   A 1 5   ? -59.178  59.386 60.947 0.70 47.50  ? 5   A   R C5    1 
ATOM   96   C C6    . A   A 1 5   ? -60.224  58.562 60.481 0.70 45.71  ? 5   A   R C6    1 
ATOM   97   N N6    . A   A 1 5   ? -60.993  57.806 61.273 0.70 42.94  ? 5   A   R N6    1 
ATOM   98   N N1    . A   A 1 5   ? -60.457  58.540 59.151 0.70 46.00  ? 5   A   R N1    1 
ATOM   99   C C2    . A   A 1 5   ? -59.691  59.290 58.350 0.70 49.76  ? 5   A   R C2    1 
ATOM   100  N N3    . A   A 1 5   ? -58.685  60.099 58.665 0.70 47.12  ? 5   A   R N3    1 
ATOM   101  C C4    . A   A 1 5   ? -58.479  60.100 59.992 0.70 47.04  ? 5   A   R C4    1 
ATOM   102  P P     . G   A 1 6   ? -58.677  65.879 60.888 0.70 41.93  ? 6   G   R P     1 
ATOM   103  O OP1   . G   A 1 6   ? -58.585  67.359 60.937 0.70 47.37  ? 6   G   R OP1   1 
ATOM   104  O OP2   . G   A 1 6   ? -59.325  65.144 62.002 0.70 30.85  ? 6   G   R OP2   1 
ATOM   105  O "O5'" . G   A 1 6   ? -59.424  65.484 59.545 0.70 42.33  ? 6   G   R "O5'" 1 
ATOM   106  C "C5'" . G   A 1 6   ? -58.824  65.764 58.291 0.70 43.55  ? 6   G   R "C5'" 1 
ATOM   107  C "C4'" . G   A 1 6   ? -59.530  65.008 57.202 0.70 53.45  ? 6   G   R "C4'" 1 
ATOM   108  O "O4'" . G   A 1 6   ? -59.436  63.583 57.478 0.70 57.86  ? 6   G   R "O4'" 1 
ATOM   109  C "C3'" . G   A 1 6   ? -61.026  65.258 57.141 0.70 46.57  ? 6   G   R "C3'" 1 
ATOM   110  O "O3'" . G   A 1 6   ? -61.324  66.442 56.429 0.70 42.66  ? 6   G   R "O3'" 1 
ATOM   111  C "C2'" . G   A 1 6   ? -61.533  64.010 56.438 0.70 47.85  ? 6   G   R "C2'" 1 
ATOM   112  O "O2'" . G   A 1 6   ? -61.370  64.055 55.035 0.70 38.20  ? 6   G   R "O2'" 1 
ATOM   113  C "C1'" . G   A 1 6   ? -60.624  62.942 57.046 0.70 51.16  ? 6   G   R "C1'" 1 
ATOM   114  N N9    . G   A 1 6   ? -61.276  62.315 58.189 0.70 48.43  ? 6   G   R N9    1 
ATOM   115  C C8    . G   A 1 6   ? -61.026  62.482 59.530 0.70 45.97  ? 6   G   R C8    1 
ATOM   116  N N7    . G   A 1 6   ? -61.819  61.769 60.288 0.70 41.97  ? 6   G   R N7    1 
ATOM   117  C C5    . G   A 1 6   ? -62.632  61.094 59.387 0.70 40.71  ? 6   G   R C5    1 
ATOM   118  C C6    . G   A 1 6   ? -63.692  60.165 59.600 0.70 45.70  ? 6   G   R C6    1 
ATOM   119  O O6    . G   A 1 6   ? -64.148  59.734 60.674 0.70 41.22  ? 6   G   R O6    1 
ATOM   120  N N1    . G   A 1 6   ? -64.237  59.735 58.392 0.70 50.89  ? 6   G   R N1    1 
ATOM   121  C C2    . G   A 1 6   ? -63.820  60.145 57.145 0.70 51.61  ? 6   G   R C2    1 
ATOM   122  N N2    . G   A 1 6   ? -64.460  59.640 56.092 0.70 50.98  ? 6   G   R N2    1 
ATOM   123  N N3    . G   A 1 6   ? -62.845  60.997 56.942 0.70 52.88  ? 6   G   R N3    1 
ATOM   124  C C4    . G   A 1 6   ? -62.301  61.426 58.091 0.70 47.92  ? 6   G   R C4    1 
ATOM   125  P P     . U   A 1 7   ? -62.656  67.258 56.782 0.70 51.54  ? 7   U   R P     1 
ATOM   126  O OP1   . U   A 1 7   ? -62.492  68.616 56.198 0.70 33.60  ? 7   U   R OP1   1 
ATOM   127  O OP2   . U   A 1 7   ? -62.897  67.108 58.243 0.70 43.70  ? 7   U   R OP2   1 
ATOM   128  O "O5'" . U   A 1 7   ? -63.804  66.460 56.007 0.70 57.42  ? 7   U   R "O5'" 1 
ATOM   129  C "C5'" . U   A 1 7   ? -65.173  66.855 56.104 0.70 51.50  ? 7   U   R "C5'" 1 
ATOM   130  C "C4'" . U   A 1 7   ? -65.949  66.386 54.890 0.70 59.95  ? 7   U   R "C4'" 1 
ATOM   131  O "O4'" . U   A 1 7   ? -65.221  66.772 53.697 0.70 66.76  ? 7   U   R "O4'" 1 
ATOM   132  C "C3'" . U   A 1 7   ? -66.069  64.862 54.833 0.70 61.50  ? 7   U   R "C3'" 1 
ATOM   133  O "O3'" . U   A 1 7   ? -67.370  64.461 54.402 0.70 57.33  ? 7   U   R "O3'" 1 
ATOM   134  C "C2'" . U   A 1 7   ? -64.954  64.391 53.901 0.70 60.13  ? 7   U   R "C2'" 1 
ATOM   135  O "O2'" . U   A 1 7   ? -65.372  63.353 53.044 0.70 60.53  ? 7   U   R "O2'" 1 
ATOM   136  C "C1'" . U   A 1 7   ? -64.744  65.627 53.030 0.70 68.79  ? 7   U   R "C1'" 1 
ATOM   137  N N1    . U   A 1 7   ? -63.409  65.883 52.476 0.70 78.51  ? 7   U   R N1    1 
ATOM   138  C C2    . U   A 1 7   ? -63.274  65.733 51.106 0.70 82.33  ? 7   U   R C2    1 
ATOM   139  O O2    . U   A 1 7   ? -64.202  65.414 50.381 0.70 80.58  ? 7   U   R O2    1 
ATOM   140  N N3    . U   A 1 7   ? -62.017  65.974 50.616 0.70 82.03  ? 7   U   R N3    1 
ATOM   141  C C4    . U   A 1 7   ? -60.908  66.342 51.338 0.70 84.74  ? 7   U   R C4    1 
ATOM   142  O O4    . U   A 1 7   ? -59.843  66.525 50.750 0.70 91.11  ? 7   U   R O4    1 
ATOM   143  C C5    . U   A 1 7   ? -61.127  66.478 52.750 0.70 82.64  ? 7   U   R C5    1 
ATOM   144  C C6    . U   A 1 7   ? -62.344  66.249 53.257 0.70 77.41  ? 7   U   R C6    1 
ATOM   145  P P     . C   A 1 8   ? -68.329  63.590 55.349 0.70 67.96  ? 8   C   R P     1 
ATOM   146  O OP1   . C   A 1 8   ? -69.134  62.748 54.427 0.70 72.28  ? 8   C   R OP1   1 
ATOM   147  O OP2   . C   A 1 8   ? -69.019  64.530 56.268 0.70 76.37  ? 8   C   R OP2   1 
ATOM   148  O "O5'" . C   A 1 8   ? -67.373  62.628 56.191 0.70 64.41  ? 8   C   R "O5'" 1 
ATOM   149  C "C5'" . C   A 1 8   ? -67.442  61.211 56.026 0.70 48.41  ? 8   C   R "C5'" 1 
ATOM   150  C "C4'" . C   A 1 8   ? -67.813  60.528 57.328 0.70 43.14  ? 8   C   R "C4'" 1 
ATOM   151  O "O4'" . C   A 1 8   ? -66.775  60.784 58.308 0.70 49.83  ? 8   C   R "O4'" 1 
ATOM   152  C "C3'" . C   A 1 8   ? -69.106  61.071 57.936 0.70 42.34  ? 8   C   R "C3'" 1 
ATOM   153  O "O3'" . C   A 1 8   ? -70.023  60.082 58.397 0.70 64.06  ? 8   C   R "O3'" 1 
ATOM   154  C "C2'" . C   A 1 8   ? -68.685  62.068 59.014 0.70 43.47  ? 8   C   R "C2'" 1 
ATOM   155  O "O2'" . C   A 1 8   ? -69.430  61.875 60.201 0.70 57.57  ? 8   C   R "O2'" 1 
ATOM   156  C "C1'" . C   A 1 8   ? -67.270  61.602 59.347 0.70 41.33  ? 8   C   R "C1'" 1 
ATOM   157  N N1    . C   A 1 8   ? -66.275  62.630 59.686 0.70 36.77  ? 8   C   R N1    1 
ATOM   158  C C2    . C   A 1 8   ? -65.931  62.804 61.037 0.70 44.94  ? 8   C   R C2    1 
ATOM   159  O O2    . C   A 1 8   ? -66.483  62.090 61.896 0.70 50.48  ? 8   C   R O2    1 
ATOM   160  N N3    . C   A 1 8   ? -65.010  63.737 61.369 0.70 44.06  ? 8   C   R N3    1 
ATOM   161  C C4    . C   A 1 8   ? -64.443  64.481 60.413 0.70 56.18  ? 8   C   R C4    1 
ATOM   162  N N4    . C   A 1 8   ? -63.536  65.392 60.777 0.70 51.36  ? 8   C   R N4    1 
ATOM   163  C C5    . C   A 1 8   ? -64.780  64.326 59.034 0.70 51.91  ? 8   C   R C5    1 
ATOM   164  C C6    . C   A 1 8   ? -65.692  63.398 58.719 0.70 36.47  ? 8   C   R C6    1 
ATOM   165  P P     . A   A 1 9   ? -70.953  59.278 57.365 0.70 64.34  ? 9   A   R P     1 
ATOM   166  O OP1   . A   A 1 9   ? -70.327  59.292 56.020 0.70 56.47  ? 9   A   R OP1   1 
ATOM   167  O OP2   . A   A 1 9   ? -72.352  59.751 57.534 0.70 50.19  ? 9   A   R OP2   1 
ATOM   168  O "O5'" . A   A 1 9   ? -70.885  57.797 57.936 0.70 51.71  ? 9   A   R "O5'" 1 
ATOM   169  C "C5'" . A   A 1 9   ? -72.009  56.941 57.873 0.70 43.04  ? 9   A   R "C5'" 1 
ATOM   170  C "C4'" . A   A 1 9   ? -71.705  55.645 58.574 0.70 35.35  ? 9   A   R "C4'" 1 
ATOM   171  O "O4'" . A   A 1 9   ? -71.561  55.887 59.998 0.70 39.76  ? 9   A   R "O4'" 1 
ATOM   172  C "C3'" . A   A 1 9   ? -72.895  54.710 58.425 0.70 36.35  ? 9   A   R "C3'" 1 
ATOM   173  O "O3'" . A   A 1 9   ? -72.499  53.388 58.099 0.70 55.45  ? 9   A   R "O3'" 1 
ATOM   174  C "C2'" . A   A 1 9   ? -73.702  54.837 59.709 0.70 30.35  ? 9   A   R "C2'" 1 
ATOM   175  O "O2'" . A   A 1 9   ? -74.193  53.591 60.152 0.70 55.20  ? 9   A   R "O2'" 1 
ATOM   176  C "C1'" . A   A 1 9   ? -72.622  55.273 60.692 0.70 31.36  ? 9   A   R "C1'" 1 
ATOM   177  N N9    . A   A 1 9   ? -73.033  56.082 61.830 0.70 17.69  ? 9   A   R N9    1 
ATOM   178  C C8    . A   A 1 9   ? -73.372  57.407 61.912 0.70 28.78  ? 9   A   R C8    1 
ATOM   179  N N7    . A   A 1 9   ? -73.699  57.792 63.123 0.70 25.67  ? 9   A   R N7    1 
ATOM   180  C C5    . A   A 1 9   ? -73.562  56.640 63.886 0.70 25.21  ? 9   A   R C5    1 
ATOM   181  C C6    . A   A 1 9   ? -73.759  56.376 65.253 0.70 12.83  ? 9   A   R C6    1 
ATOM   182  N N6    . A   A 1 9   ? -74.153  57.297 66.136 0.70 16.20  ? 9   A   R N6    1 
ATOM   183  N N1    . A   A 1 9   ? -73.536  55.116 65.687 0.70 18.27  ? 9   A   R N1    1 
ATOM   184  C C2    . A   A 1 9   ? -73.139  54.191 64.802 0.70 7.68   ? 9   A   R C2    1 
ATOM   185  N N3    . A   A 1 9   ? -72.919  54.318 63.499 0.70 13.58  ? 9   A   R N3    1 
ATOM   186  C C4    . A   A 1 9   ? -73.152  55.581 63.101 0.70 19.72  ? 9   A   R C4    1 
ATOM   187  P P     . C   A 1 10  ? -72.820  52.789 56.656 0.70 58.86  ? 10  C   R P     1 
ATOM   188  O OP1   . C   A 1 10  ? -74.037  53.448 56.111 0.70 49.49  ? 10  C   R OP1   1 
ATOM   189  O OP2   . C   A 1 10  ? -72.772  51.310 56.803 0.70 54.35  ? 10  C   R OP2   1 
ATOM   190  O "O5'" . C   A 1 10  ? -71.575  53.241 55.784 0.70 55.71  ? 10  C   R "O5'" 1 
ATOM   191  C "C5'" . C   A 1 10  ? -70.248  53.027 56.239 0.70 60.75  ? 10  C   R "C5'" 1 
ATOM   192  C "C4'" . C   A 1 10  ? -69.323  53.909 55.459 0.70 68.45  ? 10  C   R "C4'" 1 
ATOM   193  O "O4'" . C   A 1 10  ? -69.402  55.246 56.012 0.70 74.16  ? 10  C   R "O4'" 1 
ATOM   194  C "C3'" . C   A 1 10  ? -67.847  53.559 55.521 0.70 77.36  ? 10  C   R "C3'" 1 
ATOM   195  O "O3'" . C   A 1 10  ? -67.509  52.572 54.552 0.70 82.06  ? 10  C   R "O3'" 1 
ATOM   196  C "C2'" . C   A 1 10  ? -67.200  54.896 55.192 0.70 86.95  ? 10  C   R "C2'" 1 
ATOM   197  O "O2'" . C   A 1 10  ? -67.209  55.176 53.805 0.70 92.88  ? 10  C   R "O2'" 1 
ATOM   198  C "C1'" . C   A 1 10  ? -68.139  55.867 55.906 0.70 80.14  ? 10  C   R "C1'" 1 
ATOM   199  N N1    . C   A 1 10  ? -67.666  56.256 57.240 0.70 75.60  ? 10  C   R N1    1 
ATOM   200  C C2    . C   A 1 10  ? -66.632  57.166 57.297 0.70 69.97  ? 10  C   R C2    1 
ATOM   201  O O2    . C   A 1 10  ? -66.178  57.591 56.229 0.70 65.32  ? 10  C   R O2    1 
ATOM   202  N N3    . C   A 1 10  ? -66.151  57.564 58.494 0.70 65.42  ? 10  C   R N3    1 
ATOM   203  C C4    . C   A 1 10  ? -66.676  57.076 59.614 0.70 69.96  ? 10  C   R C4    1 
ATOM   204  N N4    . C   A 1 10  ? -66.164  57.505 60.774 0.70 63.94  ? 10  C   R N4    1 
ATOM   205  C C5    . C   A 1 10  ? -67.747  56.130 59.593 0.70 73.09  ? 10  C   R C5    1 
ATOM   206  C C6    . C   A 1 10  ? -68.209  55.749 58.390 0.70 73.45  ? 10  C   R C6    1 
ATOM   207  P P     . U   A 1 11  ? -66.109  51.790 54.663 0.70 84.53  ? 11  U   R P     1 
ATOM   208  O OP1   . U   A 1 11  ? -66.065  50.779 53.578 0.70 82.85  ? 11  U   R OP1   1 
ATOM   209  O OP2   . U   A 1 11  ? -65.947  51.359 56.077 0.70 89.28  ? 11  U   R OP2   1 
ATOM   210  O "O5'" . U   A 1 11  ? -65.008  52.901 54.349 0.70 86.73  ? 11  U   R "O5'" 1 
ATOM   211  C "C5'" . U   A 1 11  ? -64.838  53.395 53.025 0.70 79.45  ? 11  U   R "C5'" 1 
ATOM   212  C "C4'" . U   A 1 11  ? -63.677  54.363 52.955 0.70 79.55  ? 11  U   R "C4'" 1 
ATOM   213  O "O4'" . U   A 1 11  ? -63.985  55.549 53.741 0.70 79.79  ? 11  U   R "O4'" 1 
ATOM   214  C "C3'" . U   A 1 11  ? -62.374  53.866 53.561 0.70 82.38  ? 11  U   R "C3'" 1 
ATOM   215  O "O3'" . U   A 1 11  ? -61.633  53.043 52.674 0.70 81.17  ? 11  U   R "O3'" 1 
ATOM   216  C "C2'" . U   A 1 11  ? -61.643  55.165 53.868 0.70 86.37  ? 11  U   R "C2'" 1 
ATOM   217  O "O2'" . U   A 1 11  ? -61.032  55.730 52.724 0.70 87.85  ? 11  U   R "O2'" 1 
ATOM   218  C "C1'" . U   A 1 11  ? -62.796  56.053 54.331 0.70 83.15  ? 11  U   R "C1'" 1 
ATOM   219  N N1    . U   A 1 11  ? -62.935  56.060 55.795 0.70 79.43  ? 11  U   R N1    1 
ATOM   220  C C2    . U   A 1 11  ? -62.205  57.008 56.483 0.70 77.60  ? 11  U   R C2    1 
ATOM   221  O O2    . U   A 1 11  ? -61.483  57.815 55.925 0.70 78.41  ? 11  U   R O2    1 
ATOM   222  N N3    . U   A 1 11  ? -62.348  56.977 57.847 0.70 77.70  ? 11  U   R N3    1 
ATOM   223  C C4    . U   A 1 11  ? -63.130  56.114 58.582 0.70 75.13  ? 11  U   R C4    1 
ATOM   224  O O4    . U   A 1 11  ? -63.145  56.216 59.812 0.70 69.22  ? 11  U   R O4    1 
ATOM   225  C C5    . U   A 1 11  ? -63.861  55.157 57.800 0.70 69.62  ? 11  U   R C5    1 
ATOM   226  C C6    . U   A 1 11  ? -63.741  55.164 56.464 0.70 71.12  ? 11  U   R C6    1 
ATOM   227  P P     . G   A 1 12  ? -60.649  51.924 53.275 0.70 84.39  ? 12  G   R P     1 
ATOM   228  O OP1   . G   A 1 12  ? -60.197  51.078 52.142 0.70 87.26  ? 12  G   R OP1   1 
ATOM   229  O OP2   . G   A 1 12  ? -61.333  51.297 54.435 0.70 80.30  ? 12  G   R OP2   1 
ATOM   230  O "O5'" . G   A 1 12  ? -59.399  52.752 53.818 0.70 83.77  ? 12  G   R "O5'" 1 
ATOM   231  C "C5'" . G   A 1 12  ? -58.476  53.319 52.901 0.70 83.70  ? 12  G   R "C5'" 1 
ATOM   232  C "C4'" . G   A 1 12  ? -57.502  54.243 53.598 0.70 83.44  ? 12  G   R "C4'" 1 
ATOM   233  O "O4'" . G   A 1 12  ? -58.248  55.267 54.323 0.70 80.56  ? 12  G   R "O4'" 1 
ATOM   234  C "C3'" . G   A 1 12  ? -56.650  53.611 54.690 0.70 84.90  ? 12  G   R "C3'" 1 
ATOM   235  O "O3'" . G   A 1 12  ? -55.517  52.895 54.219 0.70 91.33  ? 12  G   R "O3'" 1 
ATOM   236  C "C2'" . G   A 1 12  ? -56.244  54.820 55.517 0.70 81.82  ? 12  G   R "C2'" 1 
ATOM   237  O "O2'" . G   A 1 12  ? -55.184  55.551 54.932 0.70 78.35  ? 12  G   R "O2'" 1 
ATOM   238  C "C1'" . G   A 1 12  ? -57.527  55.645 55.488 0.70 77.69  ? 12  G   R "C1'" 1 
ATOM   239  N N9    . G   A 1 12  ? -58.305  55.366 56.691 0.70 72.63  ? 12  G   R N9    1 
ATOM   240  C C8    . G   A 1 12  ? -59.464  54.640 56.830 0.70 71.55  ? 12  G   R C8    1 
ATOM   241  N N7    . G   A 1 12  ? -59.871  54.563 58.072 0.70 64.36  ? 12  G   R N7    1 
ATOM   242  C C5    . G   A 1 12  ? -58.925  55.287 58.789 0.70 67.98  ? 12  G   R C5    1 
ATOM   243  C C6    . G   A 1 12  ? -58.822  55.566 60.189 0.70 63.91  ? 12  G   R C6    1 
ATOM   244  O O6    . G   A 1 12  ? -59.573  55.212 61.110 0.70 51.48  ? 12  G   R O6    1 
ATOM   245  N N1    . G   A 1 12  ? -57.701  56.346 60.473 0.70 61.59  ? 12  G   R N1    1 
ATOM   246  C C2    . G   A 1 12  ? -56.795  56.798 59.540 0.70 65.31  ? 12  G   R C2    1 
ATOM   247  N N2    . G   A 1 12  ? -55.774  57.540 59.997 0.70 48.70  ? 12  G   R N2    1 
ATOM   248  N N3    . G   A 1 12  ? -56.880  56.544 58.248 0.70 67.55  ? 12  G   R N3    1 
ATOM   249  C C4    . G   A 1 12  ? -57.959  55.792 57.946 0.70 69.73  ? 12  G   R C4    1 
ATOM   250  P P     . G   A 1 13  ? -54.802  51.828 55.191 0.70 99.66  ? 13  G   R P     1 
ATOM   251  O OP1   . G   A 1 13  ? -53.701  51.168 54.443 0.70 100.00 ? 13  G   R OP1   1 
ATOM   252  O OP2   . G   A 1 13  ? -55.872  50.999 55.802 0.70 94.95  ? 13  G   R OP2   1 
ATOM   253  O "O5'" . G   A 1 13  ? -54.157  52.720 56.346 0.70 97.13  ? 13  G   R "O5'" 1 
ATOM   254  C "C5'" . G   A 1 13  ? -53.150  53.676 56.037 0.70 91.66  ? 13  G   R "C5'" 1 
ATOM   255  C "C4'" . G   A 1 13  ? -52.520  54.228 57.297 0.70 89.42  ? 13  G   R "C4'" 1 
ATOM   256  O "O4'" . G   A 1 13  ? -53.508  54.998 58.038 0.70 84.98  ? 13  G   R "O4'" 1 
ATOM   257  C "C3'" . G   A 1 13  ? -52.061  53.186 58.306 0.70 89.70  ? 13  G   R "C3'" 1 
ATOM   258  O "O3'" . G   A 1 13  ? -50.789  52.636 58.004 0.70 94.55  ? 13  G   R "O3'" 1 
ATOM   259  C "C2'" . G   A 1 13  ? -52.034  53.980 59.603 0.70 84.53  ? 13  G   R "C2'" 1 
ATOM   260  O "O2'" . G   A 1 13  ? -50.879  54.786 59.722 0.70 79.08  ? 13  G   R "O2'" 1 
ATOM   261  C "C1'" . G   A 1 13  ? -53.259  54.874 59.430 0.70 78.52  ? 13  G   R "C1'" 1 
ATOM   262  N N9    . G   A 1 13  ? -54.437  54.340 60.106 0.70 73.80  ? 13  G   R N9    1 
ATOM   263  C C8    . G   A 1 13  ? -55.498  53.654 59.563 0.70 63.22  ? 13  G   R C8    1 
ATOM   264  N N7    . G   A 1 13  ? -56.393  53.309 60.453 0.70 58.66  ? 13  G   R N7    1 
ATOM   265  C C5    . G   A 1 13  ? -55.891  53.799 61.654 0.70 63.99  ? 13  G   R C5    1 
ATOM   266  C C6    . G   A 1 13  ? -56.420  53.738 62.979 0.70 60.06  ? 13  G   R C6    1 
ATOM   267  O O6    . G   A 1 13  ? -57.478  53.224 63.369 0.70 54.31  ? 13  G   R O6    1 
ATOM   268  N N1    . G   A 1 13  ? -55.576  54.364 63.895 0.70 57.65  ? 13  G   R N1    1 
ATOM   269  C C2    . G   A 1 13  ? -54.382  54.972 63.583 0.70 63.56  ? 13  G   R C2    1 
ATOM   270  N N2    . G   A 1 13  ? -53.707  55.524 64.601 0.70 59.33  ? 13  G   R N2    1 
ATOM   271  N N3    . G   A 1 13  ? -53.885  55.037 62.361 0.70 67.24  ? 13  G   R N3    1 
ATOM   272  C C4    . G   A 1 13  ? -54.684  54.436 61.454 0.70 72.22  ? 13  G   R C4    1 
ATOM   273  P P     . G   A 1 14  ? -50.273  51.352 58.821 0.70 99.08  ? 14  G   R P     1 
ATOM   274  O OP1   . G   A 1 14  ? -49.375  50.561 57.943 0.70 100.00 ? 14  G   R OP1   1 
ATOM   275  O OP2   . G   A 1 14  ? -51.465  50.701 59.431 0.70 78.95  ? 14  G   R OP2   1 
ATOM   276  O "O5'" . G   A 1 14  ? -49.401  51.979 59.998 0.70 97.27  ? 14  G   R "O5'" 1 
ATOM   277  C "C5'" . G   A 1 14  ? -49.056  51.206 61.140 0.70 99.96  ? 14  G   R "C5'" 1 
ATOM   278  C "C4'" . G   A 1 14  ? -49.216  52.032 62.393 0.70 98.82  ? 14  G   R "C4'" 1 
ATOM   279  O "O4'" . G   A 1 14  ? -50.511  52.685 62.370 0.70 95.92  ? 14  G   R "O4'" 1 
ATOM   280  C "C3'" . G   A 1 14  ? -49.211  51.242 63.691 0.70 100.00 ? 14  G   R "C3'" 1 
ATOM   281  O "O3'" . G   A 1 14  ? -47.895  50.874 64.130 0.70 100.00 ? 14  G   R "O3'" 1 
ATOM   282  C "C2'" . G   A 1 14  ? -49.983  52.160 64.630 0.70 99.07  ? 14  G   R "C2'" 1 
ATOM   283  O "O2'" . G   A 1 14  ? -49.188  53.211 65.140 0.70 100.00 ? 14  G   R "O2'" 1 
ATOM   284  C "C1'" . G   A 1 14  ? -51.041  52.735 63.684 0.70 94.52  ? 14  G   R "C1'" 1 
ATOM   285  N N9    . G   A 1 14  ? -52.305  52.006 63.684 0.70 85.59  ? 14  G   R N9    1 
ATOM   286  C C8    . G   A 1 14  ? -52.890  51.370 62.615 0.70 82.28  ? 14  G   R C8    1 
ATOM   287  N N7    . G   A 1 14  ? -54.031  50.810 62.912 0.70 78.14  ? 14  G   R N7    1 
ATOM   288  C C5    . G   A 1 14  ? -54.210  51.091 64.259 0.70 81.68  ? 14  G   R C5    1 
ATOM   289  C C6    . G   A 1 14  ? -55.270  50.744 65.138 0.70 86.31  ? 14  G   R C6    1 
ATOM   290  O O6    . G   A 1 14  ? -56.298  50.095 64.889 0.70 81.37  ? 14  G   R O6    1 
ATOM   291  N N1    . G   A 1 14  ? -55.049  51.232 66.422 0.70 84.64  ? 14  G   R N1    1 
ATOM   292  C C2    . G   A 1 14  ? -53.952  51.962 66.815 0.70 82.51  ? 14  G   R C2    1 
ATOM   293  N N2    . G   A 1 14  ? -53.921  52.342 68.104 0.70 67.21  ? 14  G   R N2    1 
ATOM   294  N N3    . G   A 1 14  ? -52.957  52.293 66.005 0.70 77.38  ? 14  G   R N3    1 
ATOM   295  C C4    . G   A 1 14  ? -53.152  51.828 64.752 0.70 80.06  ? 14  G   R C4    1 
ATOM   296  O "O5'" . C   B 2 1   ? -86.136  47.773 28.284 0.50 39.78  ? 4   C   S "O5'" 1 
ATOM   297  C "C5'" . C   B 2 1   ? -86.110  46.932 29.443 0.50 38.96  ? 4   C   S "C5'" 1 
ATOM   298  C "C4'" . C   B 2 1   ? -85.681  45.529 29.091 0.50 44.91  ? 4   C   S "C4'" 1 
ATOM   299  O "O4'" . C   B 2 1   ? -84.293  45.347 29.473 0.50 48.94  ? 4   C   S "O4'" 1 
ATOM   300  C "C3'" . C   B 2 1   ? -86.421  44.421 29.823 0.50 47.04  ? 4   C   S "C3'" 1 
ATOM   301  O "O3'" . C   B 2 1   ? -87.621  44.082 29.146 0.50 48.75  ? 4   C   S "O3'" 1 
ATOM   302  C "C2'" . C   B 2 1   ? -85.424  43.274 29.766 0.50 48.57  ? 4   C   S "C2'" 1 
ATOM   303  O "O2'" . C   B 2 1   ? -85.443  42.579 28.536 0.50 47.15  ? 4   C   S "O2'" 1 
ATOM   304  C "C1'" . C   B 2 1   ? -84.099  44.021 29.934 0.50 53.15  ? 4   C   S "C1'" 1 
ATOM   305  N N1    . C   B 2 1   ? -83.661  44.075 31.335 0.50 58.15  ? 4   C   S N1    1 
ATOM   306  C C2    . C   B 2 1   ? -83.225  42.897 31.931 0.50 62.15  ? 4   C   S C2    1 
ATOM   307  O O2    . C   B 2 1   ? -83.221  41.858 31.255 0.50 66.29  ? 4   C   S O2    1 
ATOM   308  N N3    . C   B 2 1   ? -82.818  42.915 33.220 0.50 58.45  ? 4   C   S N3    1 
ATOM   309  C C4    . C   B 2 1   ? -82.838  44.053 33.909 0.50 59.38  ? 4   C   S C4    1 
ATOM   310  N N4    . C   B 2 1   ? -82.427  44.016 35.177 0.50 64.04  ? 4   C   S N4    1 
ATOM   311  C C5    . C   B 2 1   ? -83.280  45.278 33.326 0.50 57.82  ? 4   C   S C5    1 
ATOM   312  C C6    . C   B 2 1   ? -83.679  45.244 32.046 0.50 55.08  ? 4   C   S C6    1 
ATOM   313  P P     . A   B 2 2   ? -88.909  43.640 29.990 0.50 46.19  ? 5   A   S P     1 
ATOM   314  O OP1   . A   B 2 2   ? -90.034  43.501 29.031 0.50 29.65  ? 5   A   S OP1   1 
ATOM   315  O OP2   . A   B 2 2   ? -89.027  44.577 31.134 0.50 53.18  ? 5   A   S OP2   1 
ATOM   316  O "O5'" . A   B 2 2   ? -88.541  42.193 30.543 0.50 36.44  ? 5   A   S "O5'" 1 
ATOM   317  C "C5'" . A   B 2 2   ? -88.722  41.057 29.715 0.50 38.63  ? 5   A   S "C5'" 1 
ATOM   318  C "C4'" . A   B 2 2   ? -88.502  39.781 30.487 0.50 42.14  ? 5   A   S "C4'" 1 
ATOM   319  O "O4'" . A   B 2 2   ? -87.106  39.696 30.883 0.50 52.07  ? 5   A   S "O4'" 1 
ATOM   320  C "C3'" . A   B 2 2   ? -89.254  39.655 31.802 0.50 37.53  ? 5   A   S "C3'" 1 
ATOM   321  O "O3'" . A   B 2 2   ? -90.604  39.244 31.641 0.50 44.85  ? 5   A   S "O3'" 1 
ATOM   322  C "C2'" . A   B 2 2   ? -88.417  38.620 32.537 0.50 42.06  ? 5   A   S "C2'" 1 
ATOM   323  O "O2'" . A   B 2 2   ? -88.657  37.310 32.061 0.50 35.40  ? 5   A   S "O2'" 1 
ATOM   324  C "C1'" . A   B 2 2   ? -87.006  39.043 32.137 0.50 46.47  ? 5   A   S "C1'" 1 
ATOM   325  N N9    . A   B 2 2   ? -86.459  39.970 33.122 0.50 49.97  ? 5   A   S N9    1 
ATOM   326  C C8    . A   B 2 2   ? -86.396  41.341 33.098 0.50 50.68  ? 5   A   S C8    1 
ATOM   327  N N7    . A   B 2 2   ? -85.859  41.863 34.176 0.50 56.05  ? 5   A   S N7    1 
ATOM   328  C C5    . A   B 2 2   ? -85.543  40.760 34.960 0.50 56.17  ? 5   A   S C5    1 
ATOM   329  C C6    . A   B 2 2   ? -84.947  40.631 36.230 0.50 50.40  ? 5   A   S C6    1 
ATOM   330  N N6    . A   B 2 2   ? -84.540  41.663 36.975 0.50 42.28  ? 5   A   S N6    1 
ATOM   331  N N1    . A   B 2 2   ? -84.780  39.382 36.717 0.50 52.03  ? 5   A   S N1    1 
ATOM   332  C C2    . A   B 2 2   ? -85.183  38.341 35.976 0.50 53.90  ? 5   A   S C2    1 
ATOM   333  N N3    . A   B 2 2   ? -85.754  38.333 34.775 0.50 52.03  ? 5   A   S N3    1 
ATOM   334  C C4    . A   B 2 2   ? -85.906  39.589 34.318 0.50 56.29  ? 5   A   S C4    1 
ATOM   335  P P     . G   B 2 3   ? -91.657  39.504 32.831 0.50 50.52  ? 6   G   S P     1 
ATOM   336  O OP1   . G   B 2 3   ? -93.026  39.230 32.327 0.50 44.94  ? 6   G   S OP1   1 
ATOM   337  O OP2   . G   B 2 3   ? -91.347  40.827 33.437 0.50 48.33  ? 6   G   S OP2   1 
ATOM   338  O "O5'" . G   B 2 3   ? -91.299  38.382 33.899 0.50 45.93  ? 6   G   S "O5'" 1 
ATOM   339  C "C5'" . G   B 2 3   ? -91.212  37.020 33.508 0.50 40.92  ? 6   G   S "C5'" 1 
ATOM   340  C "C4'" . G   B 2 3   ? -90.607  36.204 34.617 0.50 44.12  ? 6   G   S "C4'" 1 
ATOM   341  O "O4'" . G   B 2 3   ? -89.257  36.674 34.876 0.50 45.78  ? 6   G   S "O4'" 1 
ATOM   342  C "C3'" . G   B 2 3   ? -91.307  36.374 35.952 0.50 46.80  ? 6   G   S "C3'" 1 
ATOM   343  O "O3'" . G   B 2 3   ? -92.423  35.506 36.042 0.50 49.63  ? 6   G   S "O3'" 1 
ATOM   344  C "C2'" . G   B 2 3   ? -90.218  35.996 36.944 0.50 47.40  ? 6   G   S "C2'" 1 
ATOM   345  O "O2'" . G   B 2 3   ? -90.090  34.598 37.111 0.50 42.19  ? 6   G   S "O2'" 1 
ATOM   346  C "C1'" . G   B 2 3   ? -88.977  36.564 36.259 0.50 44.37  ? 6   G   S "C1'" 1 
ATOM   347  N N9    . G   B 2 3   ? -88.587  37.871 36.772 0.50 47.44  ? 6   G   S N9    1 
ATOM   348  C C8    . G   B 2 3   ? -88.800  39.108 36.211 0.50 45.87  ? 6   G   S C8    1 
ATOM   349  N N7    . G   B 2 3   ? -88.313  40.086 36.929 0.50 56.04  ? 6   G   S N7    1 
ATOM   350  C C5    . G   B 2 3   ? -87.748  39.452 38.030 0.50 56.41  ? 6   G   S C5    1 
ATOM   351  C C6    . G   B 2 3   ? -87.060  39.985 39.165 0.50 55.56  ? 6   G   S C6    1 
ATOM   352  O O6    . G   B 2 3   ? -86.802  41.170 39.437 0.50 50.49  ? 6   G   S O6    1 
ATOM   353  N N1    . G   B 2 3   ? -86.658  38.972 40.032 0.50 60.48  ? 6   G   S N1    1 
ATOM   354  C C2    . G   B 2 3   ? -86.883  37.628 39.839 0.50 59.80  ? 6   G   S C2    1 
ATOM   355  N N2    . G   B 2 3   ? -86.425  36.799 40.782 0.50 64.55  ? 6   G   S N2    1 
ATOM   356  N N3    . G   B 2 3   ? -87.514  37.128 38.798 0.50 53.98  ? 6   G   S N3    1 
ATOM   357  C C4    . G   B 2 3   ? -87.914  38.086 37.942 0.50 54.19  ? 6   G   S C4    1 
ATOM   358  P P     . U   B 2 4   ? -93.536  35.769 37.165 0.50 61.48  ? 7   U   S P     1 
ATOM   359  O OP1   . U   B 2 4   ? -94.719  34.929 36.850 0.50 59.68  ? 7   U   S OP1   1 
ATOM   360  O OP2   . U   B 2 4   ? -93.690  37.245 37.283 0.50 47.69  ? 7   U   S OP2   1 
ATOM   361  O "O5'" . U   B 2 4   ? -92.868  35.234 38.509 0.50 60.95  ? 7   U   S "O5'" 1 
ATOM   362  C "C5'" . U   B 2 4   ? -92.423  36.146 39.505 0.50 65.19  ? 7   U   S "C5'" 1 
ATOM   363  C "C4'" . U   B 2 4   ? -92.729  35.614 40.880 0.50 73.32  ? 7   U   S "C4'" 1 
ATOM   364  O "O4'" . U   B 2 4   ? -94.135  35.303 40.962 0.50 72.54  ? 7   U   S "O4'" 1 
ATOM   365  C "C3'" . U   B 2 4   ? -92.002  34.340 41.271 0.50 70.82  ? 7   U   S "C3'" 1 
ATOM   366  O "O3'" . U   B 2 4   ? -90.748  34.715 41.859 0.50 73.95  ? 7   U   S "O3'" 1 
ATOM   367  C "C2'" . U   B 2 4   ? -92.970  33.611 42.213 0.50 79.17  ? 7   U   S "C2'" 1 
ATOM   368  O "O2'" . U   B 2 4   ? -92.714  33.766 43.593 0.50 81.36  ? 7   U   S "O2'" 1 
ATOM   369  C "C1'" . U   B 2 4   ? -94.328  34.232 41.858 0.50 84.32  ? 7   U   S "C1'" 1 
ATOM   370  N N1    . U   B 2 4   ? -95.377  33.357 41.314 0.50 93.09  ? 7   U   S N1    1 
ATOM   371  C C2    . U   B 2 4   ? -96.011  32.485 42.182 0.50 96.33  ? 7   U   S C2    1 
ATOM   372  O O2    . U   B 2 4   ? -95.721  32.399 43.364 0.50 98.78  ? 7   U   S O2    1 
ATOM   373  N N3    . U   B 2 4   ? -97.003  31.723 41.614 0.50 92.04  ? 7   U   S N3    1 
ATOM   374  C C4    . U   B 2 4   ? -97.411  31.740 40.294 0.50 87.61  ? 7   U   S C4    1 
ATOM   375  O O4    . U   B 2 4   ? -98.319  30.991 39.930 0.50 90.50  ? 7   U   S O4    1 
ATOM   376  C C5    . U   B 2 4   ? -96.701  32.661 39.462 0.50 85.52  ? 7   U   S C5    1 
ATOM   377  C C6    . U   B 2 4   ? -95.730  33.415 39.987 0.50 90.94  ? 7   U   S C6    1 
ATOM   378  P P     . C   B 2 5   ? -90.718  35.559 43.245 0.50 78.85  ? 8   C   S P     1 
ATOM   379  O OP1   . C   B 2 5   ? -89.871  34.824 44.217 0.50 76.31  ? 8   C   S OP1   1 
ATOM   380  O OP2   . C   B 2 5   ? -92.102  35.936 43.625 0.50 73.64  ? 8   C   S OP2   1 
ATOM   381  O "O5'" . C   B 2 5   ? -89.977  36.927 42.879 0.50 73.94  ? 8   C   S "O5'" 1 
ATOM   382  C "C5'" . C   B 2 5   ? -88.569  37.079 43.077 0.50 68.02  ? 8   C   S "C5'" 1 
ATOM   383  C "C4'" . C   B 2 5   ? -88.203  38.534 43.306 0.50 63.97  ? 8   C   S "C4'" 1 
ATOM   384  O "O4'" . C   B 2 5   ? -88.353  39.265 42.061 0.50 63.53  ? 8   C   S "O4'" 1 
ATOM   385  C "C3'" . C   B 2 5   ? -89.122  39.223 44.313 0.50 64.76  ? 8   C   S "C3'" 1 
ATOM   386  O "O3'" . C   B 2 5   ? -88.440  40.004 45.291 0.50 68.81  ? 8   C   S "O3'" 1 
ATOM   387  C "C2'" . C   B 2 5   ? -90.149  40.000 43.488 0.50 59.73  ? 8   C   S "C2'" 1 
ATOM   388  O "O2'" . C   B 2 5   ? -90.327  41.306 43.996 0.50 62.38  ? 8   C   S "O2'" 1 
ATOM   389  C "C1'" . C   B 2 5   ? -89.422  40.181 42.157 0.50 52.61  ? 8   C   S "C1'" 1 
ATOM   390  N N1    . C   B 2 5   ? -90.232  40.126 40.932 0.50 43.87  ? 8   C   S N1    1 
ATOM   391  C C2    . C   B 2 5   ? -90.664  41.332 40.371 0.50 39.69  ? 8   C   S C2    1 
ATOM   392  O O2    . C   B 2 5   ? -90.356  42.396 40.934 0.50 33.15  ? 8   C   S O2    1 
ATOM   393  N N3    . C   B 2 5   ? -91.401  41.310 39.235 0.50 33.17  ? 8   C   S N3    1 
ATOM   394  C C4    . C   B 2 5   ? -91.708  40.142 38.667 0.50 38.87  ? 8   C   S C4    1 
ATOM   395  N N4    . C   B 2 5   ? -92.434  40.161 37.549 0.50 36.05  ? 8   C   S N4    1 
ATOM   396  C C5    . C   B 2 5   ? -91.282  38.900 39.220 0.50 37.86  ? 8   C   S C5    1 
ATOM   397  C C6    . C   B 2 5   ? -90.556  38.937 40.345 0.50 37.15  ? 8   C   S C6    1 
ATOM   398  P P     . A   B 2 6   ? -87.865  39.332 46.633 0.50 66.86  ? 9   A   S P     1 
ATOM   399  O OP1   . A   B 2 6   ? -87.109  38.099 46.284 0.50 52.27  ? 9   A   S OP1   1 
ATOM   400  O OP2   . A   B 2 6   ? -88.981  39.258 47.612 0.50 59.34  ? 9   A   S OP2   1 
ATOM   401  O "O5'" . A   B 2 6   ? -86.835  40.442 47.127 0.50 57.62  ? 9   A   S "O5'" 1 
ATOM   402  C "C5'" . A   B 2 6   ? -86.007  40.254 48.266 0.50 54.80  ? 9   A   S "C5'" 1 
ATOM   403  C "C4'" . A   B 2 6   ? -84.718  41.019 48.081 0.50 46.86  ? 9   A   S "C4'" 1 
ATOM   404  O "O4'" . A   B 2 6   ? -85.029  42.359 47.626 0.50 47.41  ? 9   A   S "O4'" 1 
ATOM   405  C "C3'" . A   B 2 6   ? -83.956  41.183 49.389 0.50 48.96  ? 9   A   S "C3'" 1 
ATOM   406  O "O3'" . A   B 2 6   ? -82.568  40.920 49.264 0.50 60.41  ? 9   A   S "O3'" 1 
ATOM   407  C "C2'" . A   B 2 6   ? -84.305  42.571 49.913 0.50 39.07  ? 9   A   S "C2'" 1 
ATOM   408  O "O2'" . A   B 2 6   ? -83.167  43.246 50.402 0.50 55.71  ? 9   A   S "O2'" 1 
ATOM   409  C "C1'" . A   B 2 6   ? -84.713  43.294 48.632 0.50 35.95  ? 9   A   S "C1'" 1 
ATOM   410  N N9    . A   B 2 6   ? -85.777  44.279 48.744 0.50 18.87  ? 9   A   S N9    1 
ATOM   411  C C8    . A   B 2 6   ? -87.138  44.117 48.803 0.50 9.01   ? 9   A   S C8    1 
ATOM   412  N N7    . A   B 2 6   ? -87.795  45.246 48.898 0.50 4.25   ? 9   A   S N7    1 
ATOM   413  C C5    . A   B 2 6   ? -86.796  46.213 48.901 0.50 2.00   ? 9   A   S C5    1 
ATOM   414  C C6    . A   B 2 6   ? -86.834  47.603 48.982 0.50 2.00   ? 9   A   S C6    1 
ATOM   415  N N6    . A   B 2 6   ? -87.962  48.299 49.075 0.50 2.00   ? 9   A   S N6    1 
ATOM   416  N N1    . A   B 2 6   ? -85.657  48.267 48.960 0.50 4.11   ? 9   A   S N1    1 
ATOM   417  C C2    . A   B 2 6   ? -84.523  47.561 48.867 0.50 2.00   ? 9   A   S C2    1 
ATOM   418  N N3    . A   B 2 6   ? -84.361  46.250 48.786 0.50 2.00   ? 9   A   S N3    1 
ATOM   419  C C4    . A   B 2 6   ? -85.552  45.628 48.808 0.50 2.00   ? 9   A   S C4    1 
ATOM   420  P P     . C   B 2 7   ? -81.885  39.774 50.140 0.50 68.13  ? 10  C   S P     1 
ATOM   421  O OP1   . C   B 2 7   ? -82.917  39.167 51.019 0.50 72.00  ? 10  C   S OP1   1 
ATOM   422  O OP2   . C   B 2 7   ? -80.663  40.368 50.735 0.50 69.11  ? 10  C   S OP2   1 
ATOM   423  O "O5'" . C   B 2 7   ? -81.453  38.712 49.039 0.50 69.55  ? 10  C   S "O5'" 1 
ATOM   424  C "C5'" . C   B 2 7   ? -81.385  39.079 47.663 0.50 65.83  ? 10  C   S "C5'" 1 
ATOM   425  C "C4'" . C   B 2 7   ? -81.962  37.978 46.814 0.50 69.34  ? 10  C   S "C4'" 1 
ATOM   426  O "O4'" . C   B 2 7   ? -83.343  38.304 46.496 0.50 70.03  ? 10  C   S "O4'" 1 
ATOM   427  C "C3'" . C   B 2 7   ? -81.309  37.801 45.453 0.50 75.02  ? 10  C   S "C3'" 1 
ATOM   428  O "O3'" . C   B 2 7   ? -80.140  36.996 45.524 0.50 79.69  ? 10  C   S "O3'" 1 
ATOM   429  C "C2'" . C   B 2 7   ? -82.411  37.123 44.654 0.50 77.22  ? 10  C   S "C2'" 1 
ATOM   430  O "O2'" . C   B 2 7   ? -82.496  35.735 44.916 0.50 73.14  ? 10  C   S "O2'" 1 
ATOM   431  C "C1'" . C   B 2 7   ? -83.653  37.834 45.195 0.50 74.82  ? 10  C   S "C1'" 1 
ATOM   432  N N1    . C   B 2 7   ? -84.077  38.968 44.359 0.50 74.24  ? 10  C   S N1    1 
ATOM   433  C C2    . C   B 2 7   ? -84.539  38.693 43.073 0.50 74.42  ? 10  C   S C2    1 
ATOM   434  O O2    . C   B 2 7   ? -84.572  37.515 42.695 0.50 65.60  ? 10  C   S O2    1 
ATOM   435  N N3    . C   B 2 7   ? -84.933  39.712 42.275 0.50 76.79  ? 10  C   S N3    1 
ATOM   436  C C4    . C   B 2 7   ? -84.879  40.966 42.719 0.50 73.16  ? 10  C   S C4    1 
ATOM   437  N N4    . C   B 2 7   ? -85.281  41.938 41.889 0.50 68.58  ? 10  C   S N4    1 
ATOM   438  C C5    . C   B 2 7   ? -84.412  41.280 44.033 0.50 72.89  ? 10  C   S C5    1 
ATOM   439  C C6    . C   B 2 7   ? -84.024  40.257 44.813 0.50 70.61  ? 10  C   S C6    1 
ATOM   440  P P     . U   B 2 8   ? -79.021  37.121 44.377 0.50 84.32  ? 11  U   S P     1 
ATOM   441  O OP1   . U   B 2 8   ? -77.848  36.302 44.778 0.50 87.47  ? 11  U   S OP1   1 
ATOM   442  O OP2   . U   B 2 8   ? -78.844  38.566 44.091 0.50 84.50  ? 11  U   S OP2   1 
ATOM   443  O "O5'" . U   B 2 8   ? -79.693  36.441 43.103 0.50 89.03  ? 11  U   S "O5'" 1 
ATOM   444  C "C5'" . U   B 2 8   ? -79.885  35.032 43.053 0.50 89.19  ? 11  U   S "C5'" 1 
ATOM   445  C "C4'" . U   B 2 8   ? -80.456  34.621 41.716 0.50 87.39  ? 11  U   S "C4'" 1 
ATOM   446  O "O4'" . U   B 2 8   ? -81.772  35.216 41.553 0.50 84.63  ? 11  U   S "O4'" 1 
ATOM   447  C "C3'" . U   B 2 8   ? -79.683  35.112 40.502 0.50 89.69  ? 11  U   S "C3'" 1 
ATOM   448  O "O3'" . U   B 2 8   ? -78.595  34.253 40.187 0.50 91.13  ? 11  U   S "O3'" 1 
ATOM   449  C "C2'" . U   B 2 8   ? -80.744  35.090 39.411 0.50 89.32  ? 11  U   S "C2'" 1 
ATOM   450  O "O2'" . U   B 2 8   ? -80.955  33.799 38.877 0.50 89.62  ? 11  U   S "O2'" 1 
ATOM   451  C "C1'" . U   B 2 8   ? -81.984  35.533 40.187 0.50 84.45  ? 11  U   S "C1'" 1 
ATOM   452  N N1    . U   B 2 8   ? -82.268  36.969 40.060 0.50 82.48  ? 11  U   S N1    1 
ATOM   453  C C2    . U   B 2 8   ? -82.937  37.370 38.922 0.50 79.10  ? 11  U   S C2    1 
ATOM   454  O O2    . U   B 2 8   ? -83.280  36.586 38.051 0.50 74.35  ? 11  U   S O2    1 
ATOM   455  N N3    . U   B 2 8   ? -83.188  38.715 38.838 0.50 72.50  ? 11  U   S N3    1 
ATOM   456  C C4    . U   B 2 8   ? -82.846  39.685 39.753 0.50 68.10  ? 11  U   S C4    1 
ATOM   457  O O4    . U   B 2 8   ? -83.154  40.859 39.532 0.50 58.03  ? 11  U   S O4    1 
ATOM   458  C C5    . U   B 2 8   ? -82.151  39.195 40.907 0.50 70.89  ? 11  U   S C5    1 
ATOM   459  C C6    . U   B 2 8   ? -81.892  37.884 41.019 0.50 75.84  ? 11  U   S C6    1 
ATOM   460  P P     . G   B 2 9   ? -77.376  34.810 39.301 0.50 95.09  ? 12  G   S P     1 
ATOM   461  O OP1   . G   B 2 9   ? -76.322  33.764 39.272 0.50 94.80  ? 12  G   S OP1   1 
ATOM   462  O OP2   . G   B 2 9   ? -77.047  36.172 39.792 0.50 95.71  ? 12  G   S OP2   1 
ATOM   463  O "O5'" . G   B 2 9   ? -77.987  34.944 37.835 0.50 90.24  ? 12  G   S "O5'" 1 
ATOM   464  C "C5'" . G   B 2 9   ? -78.184  33.786 37.035 0.50 85.57  ? 12  G   S "C5'" 1 
ATOM   465  C "C4'" . G   B 2 9   ? -78.892  34.136 35.747 0.50 82.86  ? 12  G   S "C4'" 1 
ATOM   466  O "O4'" . G   B 2 9   ? -80.167  34.760 36.066 0.50 82.60  ? 12  G   S "O4'" 1 
ATOM   467  C "C3'" . G   B 2 9   ? -78.200  35.173 34.873 0.50 81.98  ? 12  G   S "C3'" 1 
ATOM   468  O "O3'" . G   B 2 9   ? -77.195  34.622 34.036 0.50 84.29  ? 12  G   S "O3'" 1 
ATOM   469  C "C2'" . G   B 2 9   ? -79.355  35.714 34.046 0.50 82.31  ? 12  G   S "C2'" 1 
ATOM   470  O "O2'" . G   B 2 9   ? -79.699  34.864 32.971 0.50 78.28  ? 12  G   S "O2'" 1 
ATOM   471  C "C1'" . G   B 2 9   ? -80.478  35.732 35.080 0.50 82.68  ? 12  G   S "C1'" 1 
ATOM   472  N N9    . G   B 2 9   ? -80.589  37.049 35.697 0.50 79.46  ? 12  G   S N9    1 
ATOM   473  C C8    . G   B 2 9   ? -80.067  37.488 36.891 0.50 76.33  ? 12  G   S C8    1 
ATOM   474  N N7    . G   B 2 9   ? -80.336  38.744 37.134 0.50 73.91  ? 12  G   S N7    1 
ATOM   475  C C5    . G   B 2 9   ? -81.082  39.152 36.035 0.50 70.84  ? 12  G   S C5    1 
ATOM   476  C C6    . G   B 2 9   ? -81.663  40.412 35.724 0.50 63.68  ? 12  G   S C6    1 
ATOM   477  O O6    . G   B 2 9   ? -81.633  41.460 36.382 0.50 44.74  ? 12  G   S O6    1 
ATOM   478  N N1    . G   B 2 9   ? -82.336  40.376 34.505 0.50 63.07  ? 12  G   S N1    1 
ATOM   479  C C2    . G   B 2 9   ? -82.438  39.271 33.689 0.50 62.49  ? 12  G   S C2    1 
ATOM   480  N N2    . G   B 2 9   ? -83.130  39.418 32.552 0.50 50.45  ? 12  G   S N2    1 
ATOM   481  N N3    . G   B 2 9   ? -81.901  38.102 33.967 0.50 66.04  ? 12  G   S N3    1 
ATOM   482  C C4    . G   B 2 9   ? -81.246  38.114 35.145 0.50 73.49  ? 12  G   S C4    1 
ATOM   483  P P     . G   B 2 10  ? -76.119  35.600 33.349 0.50 92.55  ? 13  G   S P     1 
ATOM   484  O OP1   . G   B 2 10  ? -75.198  34.776 32.525 0.50 90.18  ? 13  G   S OP1   1 
ATOM   485  O OP2   . G   B 2 10  ? -75.569  36.468 34.422 0.50 86.29  ? 13  G   S OP2   1 
ATOM   486  O "O5'" . G   B 2 10  ? -76.984  36.509 32.364 0.50 89.71  ? 13  G   S "O5'" 1 
ATOM   487  C "C5'" . G   B 2 10  ? -77.483  35.978 31.139 0.50 83.05  ? 13  G   S "C5'" 1 
ATOM   488  C "C4'" . G   B 2 10  ? -77.959  37.086 30.223 0.50 78.10  ? 13  G   S "C4'" 1 
ATOM   489  O "O4'" . G   B 2 10  ? -79.116  37.742 30.810 0.50 75.69  ? 13  G   S "O4'" 1 
ATOM   490  C "C3'" . G   B 2 10  ? -76.970  38.220 30.002 0.50 75.71  ? 13  G   S "C3'" 1 
ATOM   491  O "O3'" . G   B 2 10  ? -75.923  37.937 29.068 0.50 58.99  ? 13  G   S "O3'" 1 
ATOM   492  C "C2'" . G   B 2 10  ? -77.879  39.369 29.589 0.50 78.45  ? 13  G   S "C2'" 1 
ATOM   493  O "O2'" . G   B 2 10  ? -78.261  39.300 28.230 0.50 78.85  ? 13  G   S "O2'" 1 
ATOM   494  C "C1'" . G   B 2 10  ? -79.102  39.121 30.475 0.50 76.76  ? 13  G   S "C1'" 1 
ATOM   495  N N9    . G   B 2 10  ? -79.086  39.910 31.701 0.50 75.24  ? 13  G   S N9    1 
ATOM   496  C C8    . G   B 2 10  ? -78.740  39.487 32.962 0.50 72.00  ? 13  G   S C8    1 
ATOM   497  N N7    . G   B 2 10  ? -78.818  40.435 33.858 0.50 76.05  ? 13  G   S N7    1 
ATOM   498  C C5    . G   B 2 10  ? -79.243  41.549 33.146 0.50 77.49  ? 13  G   S C5    1 
ATOM   499  C C6    . G   B 2 10  ? -79.504  42.877 33.580 0.50 73.30  ? 13  G   S C6    1 
ATOM   500  O O6    . G   B 2 10  ? -79.410  43.347 34.719 0.50 71.63  ? 13  G   S O6    1 
ATOM   501  N N1    . G   B 2 10  ? -79.914  43.689 32.527 0.50 71.95  ? 13  G   S N1    1 
ATOM   502  C C2    . G   B 2 10  ? -80.056  43.279 31.223 0.50 71.16  ? 13  G   S C2    1 
ATOM   503  N N2    . G   B 2 10  ? -80.466  44.213 30.350 0.50 66.05  ? 13  G   S N2    1 
ATOM   504  N N3    . G   B 2 10  ? -79.815  42.046 30.804 0.50 70.50  ? 13  G   S N3    1 
ATOM   505  C C4    . G   B 2 10  ? -79.415  41.240 31.812 0.50 76.13  ? 13  G   S C4    1 
ATOM   506  N N     . ALA C 3 1   ? -94.935  54.561 75.710 1.00 94.73  ? 1   ALA A N     1 
ATOM   507  C CA    . ALA C 3 1   ? -94.021  55.659 75.286 1.00 78.02  ? 1   ALA A CA    1 
ATOM   508  C C     . ALA C 3 1   ? -93.176  55.264 74.078 1.00 77.70  ? 1   ALA A C     1 
ATOM   509  O O     . ALA C 3 1   ? -93.478  54.312 73.348 1.00 87.57  ? 1   ALA A O     1 
ATOM   510  C CB    . ALA C 3 1   ? -93.103  56.059 76.454 1.00 66.68  ? 1   ALA A CB    1 
ATOM   511  N N     . SER C 3 2   ? -92.112  56.028 73.888 1.00 59.09  ? 2   SER A N     1 
ATOM   512  C CA    . SER C 3 2   ? -91.149  55.847 72.816 1.00 42.75  ? 2   SER A CA    1 
ATOM   513  C C     . SER C 3 2   ? -90.259  57.041 73.040 1.00 40.40  ? 2   SER A C     1 
ATOM   514  O O     . SER C 3 2   ? -90.758  58.155 73.156 1.00 43.17  ? 2   SER A O     1 
ATOM   515  C CB    . SER C 3 2   ? -91.805  55.953 71.441 1.00 36.42  ? 2   SER A CB    1 
ATOM   516  O OG    . SER C 3 2   ? -90.852  56.340 70.458 1.00 33.25  ? 2   SER A OG    1 
ATOM   517  N N     . ASN C 3 3   ? -88.954  56.820 73.129 1.00 32.04  ? 3   ASN A N     1 
ATOM   518  C CA    . ASN C 3 3   ? -88.042  57.923 73.367 1.00 19.78  ? 3   ASN A CA    1 
ATOM   519  C C     . ASN C 3 3   ? -87.542  58.533 72.073 1.00 27.89  ? 3   ASN A C     1 
ATOM   520  O O     . ASN C 3 3   ? -86.786  59.507 72.097 1.00 33.37  ? 3   ASN A O     1 
ATOM   521  C CB    . ASN C 3 3   ? -86.861  57.475 74.241 1.00 17.75  ? 3   ASN A CB    1 
ATOM   522  C CG    . ASN C 3 3   ? -86.054  56.345 73.627 1.00 18.69  ? 3   ASN A CG    1 
ATOM   523  O OD1   . ASN C 3 3   ? -86.288  55.928 72.493 1.00 35.76  ? 3   ASN A OD1   1 
ATOM   524  N ND2   . ASN C 3 3   ? -85.088  55.845 74.384 1.00 27.75  ? 3   ASN A ND2   1 
ATOM   525  N N     . PHE C 3 4   ? -87.977  57.972 70.945 1.00 19.76  ? 4   PHE A N     1 
ATOM   526  C CA    . PHE C 3 4   ? -87.549  58.487 69.650 1.00 23.53  ? 4   PHE A CA    1 
ATOM   527  C C     . PHE C 3 4   ? -88.417  59.663 69.232 1.00 22.67  ? 4   PHE A C     1 
ATOM   528  O O     . PHE C 3 4   ? -89.243  59.565 68.326 1.00 37.52  ? 4   PHE A O     1 
ATOM   529  C CB    . PHE C 3 4   ? -87.601  57.391 68.586 1.00 13.09  ? 4   PHE A CB    1 
ATOM   530  C CG    . PHE C 3 4   ? -86.674  57.637 67.431 1.00 17.09  ? 4   PHE A CG    1 
ATOM   531  C CD1   . PHE C 3 4   ? -85.931  58.817 67.355 1.00 24.20  ? 4   PHE A CD1   1 
ATOM   532  C CD2   . PHE C 3 4   ? -86.535  56.694 66.425 1.00 13.52  ? 4   PHE A CD2   1 
ATOM   533  C CE1   . PHE C 3 4   ? -85.065  59.049 66.294 1.00 25.29  ? 4   PHE A CE1   1 
ATOM   534  C CE2   . PHE C 3 4   ? -85.668  56.918 65.358 1.00 25.30  ? 4   PHE A CE2   1 
ATOM   535  C CZ    . PHE C 3 4   ? -84.932  58.098 65.293 1.00 21.41  ? 4   PHE A CZ    1 
ATOM   536  N N     . THR C 3 5   ? -88.198  60.786 69.901 1.00 23.11  ? 5   THR A N     1 
ATOM   537  C CA    . THR C 3 5   ? -88.952  62.003 69.656 1.00 23.06  ? 5   THR A CA    1 
ATOM   538  C C     . THR C 3 5   ? -88.072  63.147 69.184 1.00 27.39  ? 5   THR A C     1 
ATOM   539  O O     . THR C 3 5   ? -86.840  63.071 69.229 1.00 28.37  ? 5   THR A O     1 
ATOM   540  C CB    . THR C 3 5   ? -89.650  62.460 70.939 1.00 21.77  ? 5   THR A CB    1 
ATOM   541  O OG1   . THR C 3 5   ? -88.675  62.981 71.858 1.00 34.38  ? 5   THR A OG1   1 
ATOM   542  C CG2   . THR C 3 5   ? -90.351  61.296 71.587 1.00 20.05  ? 5   THR A CG2   1 
ATOM   543  N N     . GLN C 3 6   ? -88.716  64.219 68.739 1.00 27.46  ? 6   GLN A N     1 
ATOM   544  C CA    . GLN C 3 6   ? -87.985  65.385 68.289 1.00 23.61  ? 6   GLN A CA    1 
ATOM   545  C C     . GLN C 3 6   ? -87.607  66.200 69.518 1.00 22.56  ? 6   GLN A C     1 
ATOM   546  O O     . GLN C 3 6   ? -88.237  66.089 70.569 1.00 24.97  ? 6   GLN A O     1 
ATOM   547  C CB    . GLN C 3 6   ? -88.850  66.214 67.349 1.00 21.41  ? 6   GLN A CB    1 
ATOM   548  C CG    . GLN C 3 6   ? -89.242  67.570 67.887 1.00 45.66  ? 6   GLN A CG    1 
ATOM   549  C CD    . GLN C 3 6   ? -90.441  68.144 67.170 1.00 54.40  ? 6   GLN A CD    1 
ATOM   550  O OE1   . GLN C 3 6   ? -91.461  68.432 67.789 1.00 78.03  ? 6   GLN A OE1   1 
ATOM   551  N NE2   . GLN C 3 6   ? -90.326  68.310 65.857 1.00 57.69  ? 6   GLN A NE2   1 
ATOM   552  N N     . PHE C 3 7   ? -86.564  67.008 69.389 1.00 21.20  ? 7   PHE A N     1 
ATOM   553  C CA    . PHE C 3 7   ? -86.116  67.844 70.490 1.00 16.96  ? 7   PHE A CA    1 
ATOM   554  C C     . PHE C 3 7   ? -85.350  69.038 69.945 1.00 23.89  ? 7   PHE A C     1 
ATOM   555  O O     . PHE C 3 7   ? -84.951  69.034 68.777 1.00 28.38  ? 7   PHE A O     1 
ATOM   556  C CB    . PHE C 3 7   ? -85.246  67.030 71.469 1.00 20.51  ? 7   PHE A CB    1 
ATOM   557  C CG    . PHE C 3 7   ? -83.947  66.526 70.889 1.00 21.08  ? 7   PHE A CG    1 
ATOM   558  C CD1   . PHE C 3 7   ? -83.909  65.341 70.158 1.00 25.11  ? 7   PHE A CD1   1 
ATOM   559  C CD2   . PHE C 3 7   ? -82.753  67.209 71.117 1.00 21.90  ? 7   PHE A CD2   1 
ATOM   560  C CE1   . PHE C 3 7   ? -82.703  64.843 69.665 1.00 23.13  ? 7   PHE A CE1   1 
ATOM   561  C CE2   . PHE C 3 7   ? -81.536  66.715 70.626 1.00 23.77  ? 7   PHE A CE2   1 
ATOM   562  C CZ    . PHE C 3 7   ? -81.513  65.533 69.903 1.00 17.29  ? 7   PHE A CZ    1 
ATOM   563  N N     . VAL C 3 8   ? -85.169  70.073 70.764 1.00 13.00  ? 8   VAL A N     1 
ATOM   564  C CA    . VAL C 3 8   ? -84.427  71.237 70.300 1.00 29.09  ? 8   VAL A CA    1 
ATOM   565  C C     . VAL C 3 8   ? -82.970  71.072 70.697 1.00 26.64  ? 8   VAL A C     1 
ATOM   566  O O     . VAL C 3 8   ? -82.631  70.948 71.879 1.00 24.12  ? 8   VAL A O     1 
ATOM   567  C CB    . VAL C 3 8   ? -85.025  72.599 70.828 1.00 14.66  ? 8   VAL A CB    1 
ATOM   568  C CG1   . VAL C 3 8   ? -86.231  72.344 71.653 1.00 7.63   ? 8   VAL A CG1   1 
ATOM   569  C CG2   . VAL C 3 8   ? -83.995  73.397 71.604 1.00 17.18  ? 8   VAL A CG2   1 
ATOM   570  N N     . LEU C 3 9   ? -82.127  71.045 69.671 1.00 21.60  ? 9   LEU A N     1 
ATOM   571  C CA    . LEU C 3 9   ? -80.696  70.874 69.815 1.00 24.33  ? 9   LEU A CA    1 
ATOM   572  C C     . LEU C 3 9   ? -80.038  72.174 70.244 1.00 20.58  ? 9   LEU A C     1 
ATOM   573  O O     . LEU C 3 9   ? -79.146  72.184 71.092 1.00 28.17  ? 9   LEU A O     1 
ATOM   574  C CB    . LEU C 3 9   ? -80.117  70.406 68.479 1.00 14.43  ? 9   LEU A CB    1 
ATOM   575  C CG    . LEU C 3 9   ? -78.624  70.108 68.417 1.00 20.00  ? 9   LEU A CG    1 
ATOM   576  C CD1   . LEU C 3 9   ? -78.324  68.848 69.212 1.00 14.54  ? 9   LEU A CD1   1 
ATOM   577  C CD2   . LEU C 3 9   ? -78.214  69.947 66.963 1.00 15.37  ? 9   LEU A CD2   1 
ATOM   578  N N     . VAL C 3 10  ? -80.483  73.270 69.645 1.00 22.37  ? 10  VAL A N     1 
ATOM   579  C CA    . VAL C 3 10  ? -79.932  74.576 69.959 1.00 23.35  ? 10  VAL A CA    1 
ATOM   580  C C     . VAL C 3 10  ? -81.032  75.484 70.450 1.00 21.25  ? 10  VAL A C     1 
ATOM   581  O O     . VAL C 3 10  ? -81.936  75.828 69.700 1.00 29.61  ? 10  VAL A O     1 
ATOM   582  C CB    . VAL C 3 10  ? -79.288  75.231 68.729 1.00 16.11  ? 10  VAL A CB    1 
ATOM   583  C CG1   . VAL C 3 10  ? -78.606  76.517 69.142 1.00 14.37  ? 10  VAL A CG1   1 
ATOM   584  C CG2   . VAL C 3 10  ? -78.282  74.274 68.094 1.00 19.66  ? 10  VAL A CG2   1 
ATOM   585  N N     . ASP C 3 11  ? -80.954  75.861 71.718 1.00 26.93  ? 11  ASP A N     1 
ATOM   586  C CA    . ASP C 3 11  ? -81.943  76.748 72.308 1.00 28.99  ? 11  ASP A CA    1 
ATOM   587  C C     . ASP C 3 11  ? -81.481  78.197 72.209 1.00 35.41  ? 11  ASP A C     1 
ATOM   588  O O     . ASP C 3 11  ? -80.513  78.604 72.852 1.00 41.76  ? 11  ASP A O     1 
ATOM   589  C CB    . ASP C 3 11  ? -82.175  76.383 73.772 1.00 33.25  ? 11  ASP A CB    1 
ATOM   590  C CG    . ASP C 3 11  ? -83.261  77.222 74.419 1.00 39.57  ? 11  ASP A CG    1 
ATOM   591  O OD1   . ASP C 3 11  ? -83.778  78.149 73.759 1.00 56.39  ? 11  ASP A OD1   1 
ATOM   592  O OD2   . ASP C 3 11  ? -83.600  76.950 75.591 1.00 59.35  ? 11  ASP A OD2   1 
ATOM   593  N N     . ASN C 3 12  ? -82.182  78.970 71.388 1.00 48.43  ? 12  ASN A N     1 
ATOM   594  C CA    . ASN C 3 12  ? -81.864  80.376 71.206 1.00 53.96  ? 12  ASN A CA    1 
ATOM   595  C C     . ASN C 3 12  ? -82.999  81.249 71.739 1.00 62.38  ? 12  ASN A C     1 
ATOM   596  O O     . ASN C 3 12  ? -83.203  82.376 71.283 1.00 65.36  ? 12  ASN A O     1 
ATOM   597  C CB    . ASN C 3 12  ? -81.611  80.660 69.730 1.00 47.93  ? 12  ASN A CB    1 
ATOM   598  C CG    . ASN C 3 12  ? -80.169  80.426 69.341 1.00 65.20  ? 12  ASN A CG    1 
ATOM   599  O OD1   . ASN C 3 12  ? -79.257  80.627 70.150 1.00 71.08  ? 12  ASN A OD1   1 
ATOM   600  N ND2   . ASN C 3 12  ? -79.949  79.996 68.101 1.00 64.70  ? 12  ASN A ND2   1 
ATOM   601  N N     . GLY C 3 13  ? -83.738  80.708 72.705 1.00 60.85  ? 13  GLY A N     1 
ATOM   602  C CA    . GLY C 3 13  ? -84.831  81.437 73.321 1.00 67.59  ? 13  GLY A CA    1 
ATOM   603  C C     . GLY C 3 13  ? -86.156  81.416 72.586 1.00 78.34  ? 13  GLY A C     1 
ATOM   604  O O     . GLY C 3 13  ? -86.905  82.389 72.642 1.00 90.70  ? 13  GLY A O     1 
ATOM   605  N N     . GLY C 3 14  ? -86.455  80.316 71.903 1.00 85.83  ? 14  GLY A N     1 
ATOM   606  C CA    . GLY C 3 14  ? -87.712  80.221 71.178 1.00 90.47  ? 14  GLY A CA    1 
ATOM   607  C C     . GLY C 3 14  ? -87.706  80.879 69.805 1.00 92.64  ? 14  GLY A C     1 
ATOM   608  O O     . GLY C 3 14  ? -88.558  80.585 68.966 1.00 92.75  ? 14  GLY A O     1 
ATOM   609  N N     . THR C 3 15  ? -86.746  81.771 69.574 1.00 92.02  ? 15  THR A N     1 
ATOM   610  C CA    . THR C 3 15  ? -86.634  82.469 68.296 1.00 91.93  ? 15  THR A CA    1 
ATOM   611  C C     . THR C 3 15  ? -85.277  82.189 67.651 1.00 89.17  ? 15  THR A C     1 
ATOM   612  O O     . THR C 3 15  ? -84.257  82.765 68.043 1.00 86.86  ? 15  THR A O     1 
ATOM   613  C CB    . THR C 3 15  ? -86.792  83.997 68.478 1.00 99.68  ? 15  THR A CB    1 
ATOM   614  O OG1   . THR C 3 15  ? -85.773  84.481 69.363 1.00 100.00 ? 15  THR A OG1   1 
ATOM   615  C CG2   . THR C 3 15  ? -88.168  84.330 69.055 1.00 93.08  ? 15  THR A CG2   1 
ATOM   616  N N     . GLY C 3 16  ? -85.273  81.310 66.653 1.00 79.82  ? 16  GLY A N     1 
ATOM   617  C CA    . GLY C 3 16  ? -84.033  80.954 65.985 1.00 74.02  ? 16  GLY A CA    1 
ATOM   618  C C     . GLY C 3 16  ? -83.555  79.624 66.538 1.00 69.47  ? 16  GLY A C     1 
ATOM   619  O O     . GLY C 3 16  ? -82.383  79.253 66.413 1.00 63.08  ? 16  GLY A O     1 
ATOM   620  N N     . ASP C 3 17  ? -84.488  78.913 67.162 1.00 54.73  ? 17  ASP A N     1 
ATOM   621  C CA    . ASP C 3 17  ? -84.223  77.616 67.761 1.00 40.75  ? 17  ASP A CA    1 
ATOM   622  C C     . ASP C 3 17  ? -83.981  76.559 66.703 1.00 37.87  ? 17  ASP A C     1 
ATOM   623  O O     . ASP C 3 17  ? -84.685  76.509 65.696 1.00 49.74  ? 17  ASP A O     1 
ATOM   624  C CB    . ASP C 3 17  ? -85.415  77.178 68.608 1.00 36.67  ? 17  ASP A CB    1 
ATOM   625  C CG    . ASP C 3 17  ? -85.404  77.789 69.982 1.00 44.90  ? 17  ASP A CG    1 
ATOM   626  O OD1   . ASP C 3 17  ? -84.510  78.619 70.247 1.00 46.51  ? 17  ASP A OD1   1 
ATOM   627  O OD2   . ASP C 3 17  ? -86.288  77.440 70.795 1.00 47.03  ? 17  ASP A OD2   1 
ATOM   628  N N     . VAL C 3 18  ? -82.982  75.715 66.925 1.00 37.87  ? 18  VAL A N     1 
ATOM   629  C CA    . VAL C 3 18  ? -82.716  74.639 65.987 1.00 29.51  ? 18  VAL A CA    1 
ATOM   630  C C     . VAL C 3 18  ? -83.293  73.388 66.613 1.00 31.94  ? 18  VAL A C     1 
ATOM   631  O O     . VAL C 3 18  ? -82.783  72.884 67.616 1.00 29.96  ? 18  VAL A O     1 
ATOM   632  C CB    . VAL C 3 18  ? -81.227  74.400 65.753 1.00 23.35  ? 18  VAL A CB    1 
ATOM   633  C CG1   . VAL C 3 18  ? -81.045  73.213 64.824 1.00 12.00  ? 18  VAL A CG1   1 
ATOM   634  C CG2   . VAL C 3 18  ? -80.599  75.618 65.153 1.00 31.86  ? 18  VAL A CG2   1 
ATOM   635  N N     . THR C 3 19  ? -84.385  72.913 66.039 1.00 30.11  ? 19  THR A N     1 
ATOM   636  C CA    . THR C 3 19  ? -85.012  71.715 66.536 1.00 25.48  ? 19  THR A CA    1 
ATOM   637  C C     . THR C 3 19  ? -84.712  70.616 65.516 1.00 26.38  ? 19  THR A C     1 
ATOM   638  O O     . THR C 3 19  ? -84.643  70.850 64.306 1.00 33.16  ? 19  THR A O     1 
ATOM   639  C CB    . THR C 3 19  ? -86.519  71.926 66.745 1.00 12.50  ? 19  THR A CB    1 
ATOM   640  O OG1   . THR C 3 19  ? -87.231  70.811 66.209 1.00 39.94  ? 19  THR A OG1   1 
ATOM   641  C CG2   . THR C 3 19  ? -86.977  73.211 66.067 1.00 41.90  ? 19  THR A CG2   1 
ATOM   642  N N     . VAL C 3 20  ? -84.512  69.414 66.032 1.00 27.06  ? 20  VAL A N     1 
ATOM   643  C CA    . VAL C 3 20  ? -84.140  68.270 65.227 1.00 14.22  ? 20  VAL A CA    1 
ATOM   644  C C     . VAL C 3 20  ? -85.187  67.156 65.405 1.00 16.10  ? 20  VAL A C     1 
ATOM   645  O O     . VAL C 3 20  ? -85.713  66.960 66.501 1.00 20.83  ? 20  VAL A O     1 
ATOM   646  C CB    . VAL C 3 20  ? -82.722  67.859 65.681 1.00 17.11  ? 20  VAL A CB    1 
ATOM   647  C CG1   . VAL C 3 20  ? -82.738  66.520 66.371 1.00 24.05  ? 20  VAL A CG1   1 
ATOM   648  C CG2   . VAL C 3 20  ? -81.781  67.920 64.517 1.00 26.83  ? 20  VAL A CG2   1 
ATOM   649  N N     . ALA C 3 21  ? -85.505  66.431 64.336 1.00 16.58  ? 21  ALA A N     1 
ATOM   650  C CA    . ALA C 3 21  ? -86.533  65.393 64.434 1.00 17.99  ? 21  ALA A CA    1 
ATOM   651  C C     . ALA C 3 21  ? -86.153  64.031 63.873 1.00 16.48  ? 21  ALA A C     1 
ATOM   652  O O     . ALA C 3 21  ? -85.292  63.927 63.000 1.00 24.00  ? 21  ALA A O     1 
ATOM   653  C CB    . ALA C 3 21  ? -87.793  65.872 63.768 1.00 2.00   ? 21  ALA A CB    1 
ATOM   654  N N     . PRO C 3 22  ? -86.804  62.963 64.370 1.00 18.35  ? 22  PRO A N     1 
ATOM   655  C CA    . PRO C 3 22  ? -86.527  61.596 63.911 1.00 17.04  ? 22  PRO A CA    1 
ATOM   656  C C     . PRO C 3 22  ? -86.644  61.520 62.404 1.00 16.72  ? 22  PRO A C     1 
ATOM   657  O O     . PRO C 3 22  ? -87.632  61.977 61.829 1.00 35.47  ? 22  PRO A O     1 
ATOM   658  C CB    . PRO C 3 22  ? -87.583  60.750 64.620 1.00 18.19  ? 22  PRO A CB    1 
ATOM   659  C CG    . PRO C 3 22  ? -87.948  61.550 65.833 1.00 19.01  ? 22  PRO A CG    1 
ATOM   660  C CD    . PRO C 3 22  ? -87.848  62.992 65.409 1.00 14.85  ? 22  PRO A CD    1 
ATOM   661  N N     . SER C 3 23  ? -85.629  60.954 61.765 1.00 17.13  ? 23  SER A N     1 
ATOM   662  C CA    . SER C 3 23  ? -85.617  60.846 60.315 1.00 20.40  ? 23  SER A CA    1 
ATOM   663  C C     . SER C 3 23  ? -85.229  59.456 59.833 1.00 22.83  ? 23  SER A C     1 
ATOM   664  O O     . SER C 3 23  ? -85.407  59.130 58.665 1.00 34.00  ? 23  SER A O     1 
ATOM   665  C CB    . SER C 3 23  ? -84.645  61.871 59.730 1.00 21.33  ? 23  SER A CB    1 
ATOM   666  O OG    . SER C 3 23  ? -83.485  61.978 60.535 1.00 26.69  ? 23  SER A OG    1 
ATOM   667  N N     . ASN C 3 24  ? -84.706  58.628 60.726 1.00 22.76  ? 24  ASN A N     1 
ATOM   668  C CA    . ASN C 3 24  ? -84.308  57.298 60.311 1.00 20.80  ? 24  ASN A CA    1 
ATOM   669  C C     . ASN C 3 24  ? -83.879  56.395 61.451 1.00 21.32  ? 24  ASN A C     1 
ATOM   670  O O     . ASN C 3 24  ? -83.367  56.870 62.464 1.00 33.78  ? 24  ASN A O     1 
ATOM   671  C CB    . ASN C 3 24  ? -83.169  57.409 59.310 1.00 12.31  ? 24  ASN A CB    1 
ATOM   672  C CG    . ASN C 3 24  ? -83.145  56.262 58.334 1.00 20.31  ? 24  ASN A CG    1 
ATOM   673  O OD1   . ASN C 3 24  ? -83.742  55.209 58.567 1.00 29.58  ? 24  ASN A OD1   1 
ATOM   674  N ND2   . ASN C 3 24  ? -82.450  56.456 57.229 1.00 10.42  ? 24  ASN A ND2   1 
ATOM   675  N N     . PHE C 3 25  ? -84.092  55.091 61.274 1.00 24.01  ? 25  PHE A N     1 
ATOM   676  C CA    . PHE C 3 25  ? -83.705  54.091 62.268 1.00 28.67  ? 25  PHE A CA    1 
ATOM   677  C C     . PHE C 3 25  ? -83.149  52.846 61.581 1.00 24.39  ? 25  PHE A C     1 
ATOM   678  O O     . PHE C 3 25  ? -83.032  51.787 62.191 1.00 34.93  ? 25  PHE A O     1 
ATOM   679  C CB    . PHE C 3 25  ? -84.898  53.704 63.157 1.00 21.10  ? 25  PHE A CB    1 
ATOM   680  C CG    . PHE C 3 25  ? -84.505  53.237 64.542 1.00 22.15  ? 25  PHE A CG    1 
ATOM   681  C CD1   . PHE C 3 25  ? -83.174  52.944 64.851 1.00 23.11  ? 25  PHE A CD1   1 
ATOM   682  C CD2   . PHE C 3 25  ? -85.467  53.084 65.536 1.00 18.97  ? 25  PHE A CD2   1 
ATOM   683  C CE1   . PHE C 3 25  ? -82.808  52.503 66.128 1.00 19.33  ? 25  PHE A CE1   1 
ATOM   684  C CE2   . PHE C 3 25  ? -85.109  52.645 66.816 1.00 29.09  ? 25  PHE A CE2   1 
ATOM   685  C CZ    . PHE C 3 25  ? -83.776  52.355 67.110 1.00 27.18  ? 25  PHE A CZ    1 
ATOM   686  N N     . ALA C 3 26  ? -82.794  52.985 60.310 1.00 23.80  ? 26  ALA A N     1 
ATOM   687  C CA    . ALA C 3 26  ? -82.250  51.871 59.545 1.00 22.05  ? 26  ALA A CA    1 
ATOM   688  C C     . ALA C 3 26  ? -80.895  51.413 60.077 1.00 22.36  ? 26  ALA A C     1 
ATOM   689  O O     . ALA C 3 26  ? -80.045  52.227 60.418 1.00 27.49  ? 26  ALA A O     1 
ATOM   690  C CB    . ALA C 3 26  ? -82.123  52.264 58.101 1.00 19.25  ? 26  ALA A CB    1 
ATOM   691  N N     . ASN C 3 27  ? -80.708  50.099 60.140 1.00 30.78  ? 27  ASN A N     1 
ATOM   692  C CA    . ASN C 3 27  ? -79.466  49.501 60.624 1.00 29.01  ? 27  ASN A CA    1 
ATOM   693  C C     . ASN C 3 27  ? -79.159  49.799 62.088 1.00 32.78  ? 27  ASN A C     1 
ATOM   694  O O     . ASN C 3 27  ? -77.997  49.829 62.498 1.00 33.81  ? 27  ASN A O     1 
ATOM   695  C CB    . ASN C 3 27  ? -78.301  49.949 59.750 1.00 29.90  ? 27  ASN A CB    1 
ATOM   696  C CG    . ASN C 3 27  ? -78.513  49.605 58.296 1.00 48.88  ? 27  ASN A CG    1 
ATOM   697  O OD1   . ASN C 3 27  ? -78.648  48.433 57.938 1.00 58.18  ? 27  ASN A OD1   1 
ATOM   698  N ND2   . ASN C 3 27  ? -78.552  50.624 57.446 1.00 50.32  ? 27  ASN A ND2   1 
ATOM   699  N N     . GLY C 3 28  ? -80.207  50.020 62.872 1.00 30.45  ? 28  GLY A N     1 
ATOM   700  C CA    . GLY C 3 28  ? -80.027  50.279 64.285 1.00 28.78  ? 28  GLY A CA    1 
ATOM   701  C C     . GLY C 3 28  ? -79.381  51.599 64.642 1.00 25.28  ? 28  GLY A C     1 
ATOM   702  O O     . GLY C 3 28  ? -78.905  51.773 65.758 1.00 33.14  ? 28  GLY A O     1 
ATOM   703  N N     . VAL C 3 29  ? -79.345  52.533 63.707 1.00 26.57  ? 29  VAL A N     1 
ATOM   704  C CA    . VAL C 3 29  ? -78.769  53.828 64.009 1.00 20.55  ? 29  VAL A CA    1 
ATOM   705  C C     . VAL C 3 29  ? -79.902  54.833 64.006 1.00 22.45  ? 29  VAL A C     1 
ATOM   706  O O     . VAL C 3 29  ? -80.468  55.124 62.960 1.00 20.95  ? 29  VAL A O     1 
ATOM   707  C CB    . VAL C 3 29  ? -77.730  54.247 62.967 1.00 13.43  ? 29  VAL A CB    1 
ATOM   708  C CG1   . VAL C 3 29  ? -77.154  55.609 63.324 1.00 12.12  ? 29  VAL A CG1   1 
ATOM   709  C CG2   . VAL C 3 29  ? -76.633  53.225 62.915 1.00 11.12  ? 29  VAL A CG2   1 
ATOM   710  N N     . ALA C 3 30  ? -80.248  55.339 65.183 1.00 20.23  ? 30  ALA A N     1 
ATOM   711  C CA    . ALA C 3 30  ? -81.313  56.322 65.290 1.00 20.21  ? 30  ALA A CA    1 
ATOM   712  C C     . ALA C 3 30  ? -80.770  57.635 64.742 1.00 23.74  ? 30  ALA A C     1 
ATOM   713  O O     . ALA C 3 30  ? -79.664  58.052 65.093 1.00 22.86  ? 30  ALA A O     1 
ATOM   714  C CB    . ALA C 3 30  ? -81.737  56.489 66.744 1.00 16.95  ? 30  ALA A CB    1 
ATOM   715  N N     . GLU C 3 31  ? -81.542  58.282 63.875 1.00 19.92  ? 31  GLU A N     1 
ATOM   716  C CA    . GLU C 3 31  ? -81.110  59.539 63.294 1.00 15.80  ? 31  GLU A CA    1 
ATOM   717  C C     . GLU C 3 31  ? -82.154  60.635 63.378 1.00 18.54  ? 31  GLU A C     1 
ATOM   718  O O     . GLU C 3 31  ? -83.351  60.382 63.239 1.00 28.96  ? 31  GLU A O     1 
ATOM   719  C CB    . GLU C 3 31  ? -80.727  59.342 61.836 1.00 12.39  ? 31  GLU A CB    1 
ATOM   720  C CG    . GLU C 3 31  ? -80.369  60.636 61.146 1.00 24.41  ? 31  GLU A CG    1 
ATOM   721  C CD    . GLU C 3 31  ? -80.532  60.557 59.651 1.00 31.24  ? 31  GLU A CD    1 
ATOM   722  O OE1   . GLU C 3 31  ? -81.681  60.696 59.173 1.00 33.69  ? 31  GLU A OE1   1 
ATOM   723  O OE2   . GLU C 3 31  ? -79.506  60.354 58.961 1.00 24.84  ? 31  GLU A OE2   1 
ATOM   724  N N     . TRP C 3 32  ? -81.676  61.857 63.603 1.00 18.68  ? 32  TRP A N     1 
ATOM   725  C CA    . TRP C 3 32  ? -82.518  63.045 63.693 1.00 15.42  ? 32  TRP A CA    1 
ATOM   726  C C     . TRP C 3 32  ? -81.882  64.078 62.767 1.00 16.46  ? 32  TRP A C     1 
ATOM   727  O O     . TRP C 3 32  ? -80.664  64.068 62.582 1.00 23.67  ? 32  TRP A O     1 
ATOM   728  C CB    . TRP C 3 32  ? -82.486  63.647 65.099 1.00 12.43  ? 32  TRP A CB    1 
ATOM   729  C CG    . TRP C 3 32  ? -83.126  62.886 66.219 1.00 16.50  ? 32  TRP A CG    1 
ATOM   730  C CD1   . TRP C 3 32  ? -84.321  63.167 66.813 1.00 13.08  ? 32  TRP A CD1   1 
ATOM   731  C CD2   . TRP C 3 32  ? -82.540  61.821 66.983 1.00 19.16  ? 32  TRP A CD2   1 
ATOM   732  N NE1   . TRP C 3 32  ? -84.514  62.353 67.902 1.00 17.97  ? 32  TRP A NE1   1 
ATOM   733  C CE2   . TRP C 3 32  ? -83.438  61.516 68.031 1.00 15.14  ? 32  TRP A CE2   1 
ATOM   734  C CE3   . TRP C 3 32  ? -81.340  61.098 66.887 1.00 14.96  ? 32  TRP A CE3   1 
ATOM   735  C CZ2   . TRP C 3 32  ? -83.178  60.516 68.979 1.00 11.77  ? 32  TRP A CZ2   1 
ATOM   736  C CZ3   . TRP C 3 32  ? -81.079  60.101 67.833 1.00 19.88  ? 32  TRP A CZ3   1 
ATOM   737  C CH2   . TRP C 3 32  ? -81.999  59.822 68.866 1.00 17.18  ? 32  TRP A CH2   1 
ATOM   738  N N     . ILE C 3 33  ? -82.691  64.967 62.193 1.00 18.06  ? 33  ILE A N     1 
ATOM   739  C CA    . ILE C 3 33  ? -82.169  66.040 61.338 1.00 22.94  ? 33  ILE A CA    1 
ATOM   740  C C     . ILE C 3 33  ? -83.049  67.268 61.502 1.00 22.21  ? 33  ILE A C     1 
ATOM   741  O O     . ILE C 3 33  ? -84.201  67.156 61.927 1.00 25.48  ? 33  ILE A O     1 
ATOM   742  C CB    . ILE C 3 33  ? -82.150  65.680 59.835 1.00 21.89  ? 33  ILE A CB    1 
ATOM   743  C CG1   . ILE C 3 33  ? -83.565  65.368 59.361 1.00 19.04  ? 33  ILE A CG1   1 
ATOM   744  C CG2   . ILE C 3 33  ? -81.207  64.516 59.578 1.00 19.31  ? 33  ILE A CG2   1 
ATOM   745  C CD1   . ILE C 3 33  ? -83.634  65.032 57.898 1.00 29.80  ? 33  ILE A CD1   1 
ATOM   746  N N     . SER C 3 34  ? -82.498  68.436 61.175 1.00 20.56  ? 34  SER A N     1 
ATOM   747  C CA    . SER C 3 34  ? -83.239  69.690 61.275 1.00 22.45  ? 34  SER A CA    1 
ATOM   748  C C     . SER C 3 34  ? -84.042  69.834 60.002 1.00 25.92  ? 34  SER A C     1 
ATOM   749  O O     . SER C 3 34  ? -83.706  69.227 58.987 1.00 26.18  ? 34  SER A O     1 
ATOM   750  C CB    . SER C 3 34  ? -82.288  70.878 61.408 1.00 26.08  ? 34  SER A CB    1 
ATOM   751  O OG    . SER C 3 34  ? -81.286  70.854 60.404 1.00 16.37  ? 34  SER A OG    1 
ATOM   752  N N     . SER C 3 35  ? -85.101  70.634 60.057 1.00 35.48  ? 35  SER A N     1 
ATOM   753  C CA    . SER C 3 35  ? -85.965  70.855 58.899 1.00 29.68  ? 35  SER A CA    1 
ATOM   754  C C     . SER C 3 35  ? -85.264  71.655 57.801 1.00 26.96  ? 35  SER A C     1 
ATOM   755  O O     . SER C 3 35  ? -85.640  72.785 57.513 1.00 42.80  ? 35  SER A O     1 
ATOM   756  C CB    . SER C 3 35  ? -87.229  71.583 59.342 1.00 24.50  ? 35  SER A CB    1 
ATOM   757  O OG    . SER C 3 35  ? -88.277  71.400 58.407 1.00 77.89  ? 35  SER A OG    1 
ATOM   758  N N     . ASN C 3 36  ? -84.248  71.057 57.189 1.00 33.81  ? 36  ASN A N     1 
ATOM   759  C CA    . ASN C 3 36  ? -83.475  71.707 56.134 1.00 31.01  ? 36  ASN A CA    1 
ATOM   760  C C     . ASN C 3 36  ? -83.264  70.746 54.987 1.00 28.71  ? 36  ASN A C     1 
ATOM   761  O O     . ASN C 3 36  ? -83.745  69.617 55.012 1.00 38.34  ? 36  ASN A O     1 
ATOM   762  C CB    . ASN C 3 36  ? -82.085  72.106 56.642 1.00 27.52  ? 36  ASN A CB    1 
ATOM   763  C CG    . ASN C 3 36  ? -82.133  73.183 57.685 1.00 32.24  ? 36  ASN A CG    1 
ATOM   764  O OD1   . ASN C 3 36  ? -82.025  72.913 58.880 1.00 55.11  ? 36  ASN A OD1   1 
ATOM   765  N ND2   . ASN C 3 36  ? -82.289  74.420 57.243 1.00 53.02  ? 36  ASN A ND2   1 
ATOM   766  N N     . SER C 3 37  ? -82.534  71.208 53.979 1.00 29.60  ? 37  SER A N     1 
ATOM   767  C CA    . SER C 3 37  ? -82.205  70.365 52.850 1.00 20.96  ? 37  SER A CA    1 
ATOM   768  C C     . SER C 3 37  ? -81.141  69.467 53.460 1.00 26.62  ? 37  SER A C     1 
ATOM   769  O O     . SER C 3 37  ? -80.398  69.877 54.354 1.00 26.78  ? 37  SER A O     1 
ATOM   770  C CB    . SER C 3 37  ? -81.627  71.192 51.694 1.00 28.19  ? 37  SER A CB    1 
ATOM   771  O OG    . SER C 3 37  ? -80.224  71.371 51.818 1.00 34.11  ? 37  SER A OG    1 
ATOM   772  N N     . ARG C 3 38  ? -81.085  68.233 53.000 1.00 30.00  ? 38  ARG A N     1 
ATOM   773  C CA    . ARG C 3 38  ? -80.127  67.280 53.520 1.00 19.44  ? 38  ARG A CA    1 
ATOM   774  C C     . ARG C 3 38  ? -78.692  67.824 53.451 1.00 17.68  ? 38  ARG A C     1 
ATOM   775  O O     . ARG C 3 38  ? -77.828  67.429 54.227 1.00 34.13  ? 38  ARG A O     1 
ATOM   776  C CB    . ARG C 3 38  ? -80.275  65.985 52.728 1.00 22.51  ? 38  ARG A CB    1 
ATOM   777  C CG    . ARG C 3 38  ? -80.021  64.729 53.505 1.00 31.15  ? 38  ARG A CG    1 
ATOM   778  C CD    . ARG C 3 38  ? -81.228  64.173 54.248 1.00 8.17   ? 38  ARG A CD    1 
ATOM   779  N NE    . ARG C 3 38  ? -80.702  63.222 55.231 1.00 33.31  ? 38  ARG A NE    1 
ATOM   780  C CZ    . ARG C 3 38  ? -81.423  62.461 56.044 1.00 23.58  ? 38  ARG A CZ    1 
ATOM   781  N NH1   . ARG C 3 38  ? -82.742  62.511 56.024 1.00 33.29  ? 38  ARG A NH1   1 
ATOM   782  N NH2   . ARG C 3 38  ? -80.809  61.655 56.894 1.00 36.60  ? 38  ARG A NH2   1 
ATOM   783  N N     . SER C 3 39  ? -78.442  68.754 52.540 1.00 23.56  ? 39  SER A N     1 
ATOM   784  C CA    . SER C 3 39  ? -77.105  69.321 52.391 1.00 24.15  ? 39  SER A CA    1 
ATOM   785  C C     . SER C 3 39  ? -76.767  70.400 53.423 1.00 26.22  ? 39  SER A C     1 
ATOM   786  O O     . SER C 3 39  ? -75.595  70.705 53.649 1.00 23.79  ? 39  SER A O     1 
ATOM   787  C CB    . SER C 3 39  ? -76.933  69.900 50.982 1.00 16.63  ? 39  SER A CB    1 
ATOM   788  O OG    . SER C 3 39  ? -77.619  71.139 50.849 1.00 27.29  ? 39  SER A OG    1 
ATOM   789  N N     . GLN C 3 40  ? -77.784  70.977 54.052 1.00 27.32  ? 40  GLN A N     1 
ATOM   790  C CA    . GLN C 3 40  ? -77.554  72.031 55.038 1.00 32.35  ? 40  GLN A CA    1 
ATOM   791  C C     . GLN C 3 40  ? -78.067  71.662 56.419 1.00 29.73  ? 40  GLN A C     1 
ATOM   792  O O     . GLN C 3 40  ? -78.123  72.514 57.307 1.00 43.46  ? 40  GLN A O     1 
ATOM   793  C CB    . GLN C 3 40  ? -78.264  73.318 54.612 1.00 20.68  ? 40  GLN A CB    1 
ATOM   794  C CG    . GLN C 3 40  ? -77.754  73.963 53.346 1.00 33.78  ? 40  GLN A CG    1 
ATOM   795  C CD    . GLN C 3 40  ? -78.323  75.358 53.154 1.00 38.12  ? 40  GLN A CD    1 
ATOM   796  O OE1   . GLN C 3 40  ? -79.431  75.655 53.605 1.00 34.32  ? 40  GLN A OE1   1 
ATOM   797  N NE2   . GLN C 3 40  ? -77.567  76.223 52.485 1.00 48.77  ? 40  GLN A NE2   1 
ATOM   798  N N     . ALA C 3 41  ? -78.428  70.403 56.619 1.00 26.15  ? 41  ALA A N     1 
ATOM   799  C CA    . ALA C 3 41  ? -79.003  70.013 57.896 1.00 24.22  ? 41  ALA A CA    1 
ATOM   800  C C     . ALA C 3 41  ? -78.085  69.688 59.055 1.00 23.69  ? 41  ALA A C     1 
ATOM   801  O O     . ALA C 3 41  ? -76.922  69.322 58.881 1.00 20.89  ? 41  ALA A O     1 
ATOM   802  C CB    . ALA C 3 41  ? -79.960  68.857 57.685 1.00 13.23  ? 41  ALA A CB    1 
ATOM   803  N N     . TYR C 3 42  ? -78.644  69.860 60.251 1.00 23.33  ? 42  TYR A N     1 
ATOM   804  C CA    . TYR C 3 42  ? -77.970  69.529 61.494 1.00 21.25  ? 42  TYR A CA    1 
ATOM   805  C C     . TYR C 3 42  ? -78.295  68.038 61.575 1.00 18.69  ? 42  TYR A C     1 
ATOM   806  O O     . TYR C 3 42  ? -79.419  67.635 61.280 1.00 30.43  ? 42  TYR A O     1 
ATOM   807  C CB    . TYR C 3 42  ? -78.631  70.247 62.669 1.00 16.84  ? 42  TYR A CB    1 
ATOM   808  C CG    . TYR C 3 42  ? -78.157  71.659 62.902 1.00 21.94  ? 42  TYR A CG    1 
ATOM   809  C CD1   . TYR C 3 42  ? -78.656  72.706 62.145 1.00 19.39  ? 42  TYR A CD1   1 
ATOM   810  C CD2   . TYR C 3 42  ? -77.249  71.957 63.922 1.00 27.32  ? 42  TYR A CD2   1 
ATOM   811  C CE1   . TYR C 3 42  ? -78.272  74.023 62.395 1.00 26.55  ? 42  TYR A CE1   1 
ATOM   812  C CE2   . TYR C 3 42  ? -76.856  73.275 64.182 1.00 22.21  ? 42  TYR A CE2   1 
ATOM   813  C CZ    . TYR C 3 42  ? -77.377  74.302 63.412 1.00 25.59  ? 42  TYR A CZ    1 
ATOM   814  O OH    . TYR C 3 42  ? -77.028  75.611 63.659 1.00 32.24  ? 42  TYR A OH    1 
ATOM   815  N N     . LYS C 3 43  ? -77.336  67.215 61.967 1.00 21.72  ? 43  LYS A N     1 
ATOM   816  C CA    . LYS C 3 43  ? -77.583  65.780 62.032 1.00 16.73  ? 43  LYS A CA    1 
ATOM   817  C C     . LYS C 3 43  ? -77.161  65.197 63.376 1.00 22.94  ? 43  LYS A C     1 
ATOM   818  O O     . LYS C 3 43  ? -76.094  65.534 63.897 1.00 26.75  ? 43  LYS A O     1 
ATOM   819  C CB    . LYS C 3 43  ? -76.813  65.098 60.895 1.00 20.31  ? 43  LYS A CB    1 
ATOM   820  C CG    . LYS C 3 43  ? -77.254  63.692 60.519 1.00 18.99  ? 43  LYS A CG    1 
ATOM   821  C CD    . LYS C 3 43  ? -76.201  63.061 59.599 1.00 31.98  ? 43  LYS A CD    1 
ATOM   822  C CE    . LYS C 3 43  ? -76.708  61.811 58.901 1.00 49.11  ? 43  LYS A CE    1 
ATOM   823  N NZ    . LYS C 3 43  ? -75.655  61.214 58.033 1.00 67.92  ? 43  LYS A NZ    1 
ATOM   824  N N     . VAL C 3 44  ? -78.005  64.339 63.944 1.00 20.08  ? 44  VAL A N     1 
ATOM   825  C CA    . VAL C 3 44  ? -77.685  63.688 65.211 1.00 16.38  ? 44  VAL A CA    1 
ATOM   826  C C     . VAL C 3 44  ? -77.973  62.198 65.082 1.00 20.28  ? 44  VAL A C     1 
ATOM   827  O O     . VAL C 3 44  ? -79.054  61.807 64.638 1.00 25.98  ? 44  VAL A O     1 
ATOM   828  C CB    . VAL C 3 44  ? -78.526  64.236 66.384 1.00 19.39  ? 44  VAL A CB    1 
ATOM   829  C CG1   . VAL C 3 44  ? -78.157  63.502 67.662 1.00 9.25   ? 44  VAL A CG1   1 
ATOM   830  C CG2   . VAL C 3 44  ? -78.294  65.723 66.555 1.00 17.94  ? 44  VAL A CG2   1 
ATOM   831  N N     . THR C 3 45  ? -77.002  61.367 65.449 1.00 19.89  ? 45  THR A N     1 
ATOM   832  C CA    . THR C 3 45  ? -77.185  59.920 65.390 1.00 11.57  ? 45  THR A CA    1 
ATOM   833  C C     . THR C 3 45  ? -76.766  59.279 66.694 1.00 18.08  ? 45  THR A C     1 
ATOM   834  O O     . THR C 3 45  ? -75.894  59.782 67.412 1.00 19.58  ? 45  THR A O     1 
ATOM   835  C CB    . THR C 3 45  ? -76.383  59.272 64.263 1.00 11.14  ? 45  THR A CB    1 
ATOM   836  O OG1   . THR C 3 45  ? -74.984  59.506 64.471 1.00 14.32  ? 45  THR A OG1   1 
ATOM   837  C CG2   . THR C 3 45  ? -76.818  59.840 62.933 1.00 6.47   ? 45  THR A CG2   1 
ATOM   838  N N     . CYS C 3 46  ? -77.397  58.155 66.994 1.00 15.97  ? 46  CYS A N     1 
ATOM   839  C CA    . CYS C 3 46  ? -77.119  57.455 68.225 1.00 19.69  ? 46  CYS A CA    1 
ATOM   840  C C     . CYS C 3 46  ? -77.304  55.959 68.042 1.00 20.14  ? 46  CYS A C     1 
ATOM   841  O O     . CYS C 3 46  ? -78.199  55.513 67.321 1.00 13.50  ? 46  CYS A O     1 
ATOM   842  C CB    . CYS C 3 46  ? -78.053  57.973 69.316 1.00 10.29  ? 46  CYS A CB    1 
ATOM   843  S SG    . CYS C 3 46  ? -78.018  57.014 70.832 1.00 24.42  ? 46  CYS A SG    1 
ATOM   844  N N     . SER C 3 47  ? -76.448  55.184 68.695 1.00 21.37  ? 47  SER A N     1 
ATOM   845  C CA    . SER C 3 47  ? -76.529  53.738 68.606 1.00 17.61  ? 47  SER A CA    1 
ATOM   846  C C     . SER C 3 47  ? -75.914  53.073 69.837 1.00 20.58  ? 47  SER A C     1 
ATOM   847  O O     . SER C 3 47  ? -74.955  53.581 70.422 1.00 28.56  ? 47  SER A O     1 
ATOM   848  C CB    . SER C 3 47  ? -75.830  53.259 67.331 1.00 8.23   ? 47  SER A CB    1 
ATOM   849  O OG    . SER C 3 47  ? -74.427  53.188 67.506 1.00 26.67  ? 47  SER A OG    1 
ATOM   850  N N     . VAL C 3 48  ? -76.496  51.950 70.241 1.00 14.39  ? 48  VAL A N     1 
ATOM   851  C CA    . VAL C 3 48  ? -76.005  51.191 71.386 1.00 22.86  ? 48  VAL A CA    1 
ATOM   852  C C     . VAL C 3 48  ? -75.704  49.788 70.932 1.00 23.21  ? 48  VAL A C     1 
ATOM   853  O O     . VAL C 3 48  ? -76.499  49.174 70.226 1.00 32.44  ? 48  VAL A O     1 
ATOM   854  C CB    . VAL C 3 48  ? -77.045  51.019 72.512 1.00 6.55   ? 48  VAL A CB    1 
ATOM   855  C CG1   . VAL C 3 48  ? -76.356  51.150 73.852 1.00 19.32  ? 48  VAL A CG1   1 
ATOM   856  C CG2   . VAL C 3 48  ? -78.169  52.013 72.364 1.00 18.08  ? 48  VAL A CG2   1 
ATOM   857  N N     . ARG C 3 49  ? -74.560  49.273 71.345 1.00 24.12  ? 49  ARG A N     1 
ATOM   858  C CA    . ARG C 3 49  ? -74.201  47.917 70.997 1.00 26.22  ? 49  ARG A CA    1 
ATOM   859  C C     . ARG C 3 49  ? -73.580  47.309 72.239 1.00 24.42  ? 49  ARG A C     1 
ATOM   860  O O     . ARG C 3 49  ? -73.110  48.030 73.113 1.00 27.88  ? 49  ARG A O     1 
ATOM   861  C CB    . ARG C 3 49  ? -73.216  47.906 69.822 1.00 23.20  ? 49  ARG A CB    1 
ATOM   862  C CG    . ARG C 3 49  ? -71.750  47.847 70.214 1.00 57.85  ? 49  ARG A CG    1 
ATOM   863  C CD    . ARG C 3 49  ? -70.848  48.128 69.017 1.00 81.48  ? 49  ARG A CD    1 
ATOM   864  N NE    . ARG C 3 49  ? -69.430  48.031 69.361 1.00 97.77  ? 49  ARG A NE    1 
ATOM   865  C CZ    . ARG C 3 49  ? -68.556  49.030 69.242 1.00 100.00 ? 49  ARG A CZ    1 
ATOM   866  N NH1   . ARG C 3 49  ? -68.953  50.214 68.785 1.00 100.00 ? 49  ARG A NH1   1 
ATOM   867  N NH2   . ARG C 3 49  ? -67.283  48.846 69.582 1.00 100.00 ? 49  ARG A NH2   1 
ATOM   868  N N     . GLN C 3 50  ? -73.618  45.988 72.342 1.00 34.34  ? 50  GLN A N     1 
ATOM   869  C CA    . GLN C 3 50  ? -73.012  45.320 73.478 1.00 30.69  ? 50  GLN A CA    1 
ATOM   870  C C     . GLN C 3 50  ? -71.575  45.034 73.045 1.00 39.12  ? 50  GLN A C     1 
ATOM   871  O O     . GLN C 3 50  ? -71.289  43.969 72.510 1.00 46.66  ? 50  GLN A O     1 
ATOM   872  C CB    . GLN C 3 50  ? -73.749  44.023 73.779 1.00 21.69  ? 50  GLN A CB    1 
ATOM   873  C CG    . GLN C 3 50  ? -73.185  43.261 74.951 1.00 36.84  ? 50  GLN A CG    1 
ATOM   874  C CD    . GLN C 3 50  ? -74.050  43.378 76.184 1.00 54.78  ? 50  GLN A CD    1 
ATOM   875  O OE1   . GLN C 3 50  ? -75.208  43.804 76.115 1.00 52.13  ? 50  GLN A OE1   1 
ATOM   876  N NE2   . GLN C 3 50  ? -73.491  42.998 77.327 1.00 63.22  ? 50  GLN A NE2   1 
ATOM   877  N N     . SER C 3 51  ? -70.685  46.004 73.276 1.00 54.26  ? 51  SER A N     1 
ATOM   878  C CA    . SER C 3 51  ? -69.269  45.921 72.895 1.00 60.41  ? 51  SER A CA    1 
ATOM   879  C C     . SER C 3 51  ? -68.515  44.675 73.376 1.00 60.84  ? 51  SER A C     1 
ATOM   880  O O     . SER C 3 51  ? -67.896  43.967 72.578 1.00 73.59  ? 51  SER A O     1 
ATOM   881  C CB    . SER C 3 51  ? -68.530  47.191 73.353 1.00 53.40  ? 51  SER A CB    1 
ATOM   882  O OG    . SER C 3 51  ? -68.339  47.216 74.759 1.00 67.25  ? 51  SER A OG    1 
ATOM   883  N N     . SER C 3 52  ? -68.548  44.417 74.676 1.00 54.14  ? 52  SER A N     1 
ATOM   884  C CA    . SER C 3 52  ? -67.877  43.252 75.234 1.00 42.65  ? 52  SER A CA    1 
ATOM   885  C C     . SER C 3 52  ? -68.952  42.400 75.879 1.00 47.35  ? 52  SER A C     1 
ATOM   886  O O     . SER C 3 52  ? -70.146  42.669 75.728 1.00 44.56  ? 52  SER A O     1 
ATOM   887  C CB    . SER C 3 52  ? -66.831  43.678 76.282 1.00 45.64  ? 52  SER A CB    1 
ATOM   888  O OG    . SER C 3 52  ? -67.120  43.172 77.583 1.00 50.73  ? 52  SER A OG    1 
ATOM   889  N N     . ALA C 3 53  ? -68.534  41.366 76.594 1.00 49.94  ? 53  ALA A N     1 
ATOM   890  C CA    . ALA C 3 53  ? -69.491  40.510 77.265 1.00 51.79  ? 53  ALA A CA    1 
ATOM   891  C C     . ALA C 3 53  ? -70.070  41.270 78.457 1.00 55.33  ? 53  ALA A C     1 
ATOM   892  O O     . ALA C 3 53  ? -71.198  41.011 78.889 1.00 53.42  ? 53  ALA A O     1 
ATOM   893  C CB    . ALA C 3 53  ? -68.805  39.237 77.735 1.00 47.40  ? 53  ALA A CB    1 
ATOM   894  N N     . GLN C 3 54  ? -69.302  42.232 78.963 1.00 43.76  ? 54  GLN A N     1 
ATOM   895  C CA    . GLN C 3 54  ? -69.724  42.990 80.124 1.00 28.56  ? 54  GLN A CA    1 
ATOM   896  C C     . GLN C 3 54  ? -69.844  44.490 79.945 1.00 27.54  ? 54  GLN A C     1 
ATOM   897  O O     . GLN C 3 54  ? -69.984  45.224 80.921 1.00 32.04  ? 54  GLN A O     1 
ATOM   898  C CB    . GLN C 3 54  ? -68.775  42.683 81.267 1.00 37.82  ? 54  GLN A CB    1 
ATOM   899  C CG    . GLN C 3 54  ? -68.723  41.202 81.591 1.00 41.14  ? 54  GLN A CG    1 
ATOM   900  C CD    . GLN C 3 54  ? -67.723  40.884 82.679 1.00 58.47  ? 54  GLN A CD    1 
ATOM   901  O OE1   . GLN C 3 54  ? -66.976  41.762 83.135 1.00 49.84  ? 54  GLN A OE1   1 
ATOM   902  N NE2   . GLN C 3 54  ? -67.700  39.624 83.105 1.00 51.79  ? 54  GLN A NE2   1 
ATOM   903  N N     . ASN C 3 55  ? -69.811  44.950 78.703 1.00 27.15  ? 55  ASN A N     1 
ATOM   904  C CA    . ASN C 3 55  ? -69.914  46.378 78.430 1.00 18.89  ? 55  ASN A CA    1 
ATOM   905  C C     . ASN C 3 55  ? -70.952  46.678 77.391 1.00 15.44  ? 55  ASN A C     1 
ATOM   906  O O     . ASN C 3 55  ? -71.301  45.830 76.581 1.00 33.12  ? 55  ASN A O     1 
ATOM   907  C CB    . ASN C 3 55  ? -68.588  46.929 77.915 1.00 16.71  ? 55  ASN A CB    1 
ATOM   908  C CG    . ASN C 3 55  ? -67.570  47.075 79.000 1.00 32.49  ? 55  ASN A CG    1 
ATOM   909  O OD1   . ASN C 3 55  ? -66.386  46.831 78.788 1.00 65.19  ? 55  ASN A OD1   1 
ATOM   910  N ND2   . ASN C 3 55  ? -68.022  47.473 80.183 1.00 58.78  ? 55  ASN A ND2   1 
ATOM   911  N N     . ARG C 3 56  ? -71.440  47.905 77.424 1.00 18.31  ? 56  ARG A N     1 
ATOM   912  C CA    . ARG C 3 56  ? -72.398  48.371 76.441 1.00 20.07  ? 56  ARG A CA    1 
ATOM   913  C C     . ARG C 3 56  ? -71.822  49.706 76.000 1.00 25.25  ? 56  ARG A C     1 
ATOM   914  O O     . ARG C 3 56  ? -71.294  50.462 76.823 1.00 23.50  ? 56  ARG A O     1 
ATOM   915  C CB    . ARG C 3 56  ? -73.781  48.527 77.056 1.00 11.93  ? 56  ARG A CB    1 
ATOM   916  C CG    . ARG C 3 56  ? -74.655  47.330 76.789 1.00 16.09  ? 56  ARG A CG    1 
ATOM   917  C CD    . ARG C 3 56  ? -75.926  47.391 77.584 1.00 20.80  ? 56  ARG A CD    1 
ATOM   918  N NE    . ARG C 3 56  ? -76.945  48.217 76.945 1.00 31.06  ? 56  ARG A NE    1 
ATOM   919  C CZ    . ARG C 3 56  ? -77.286  49.430 77.371 1.00 48.14  ? 56  ARG A CZ    1 
ATOM   920  N NH1   . ARG C 3 56  ? -76.681  49.951 78.435 1.00 22.28  ? 56  ARG A NH1   1 
ATOM   921  N NH2   . ARG C 3 56  ? -78.244  50.114 76.753 1.00 36.01  ? 56  ARG A NH2   1 
ATOM   922  N N     . LYS C 3 57  ? -71.886  49.985 74.704 1.00 18.11  ? 57  LYS A N     1 
ATOM   923  C CA    . LYS C 3 57  ? -71.319  51.215 74.194 1.00 13.48  ? 57  LYS A CA    1 
ATOM   924  C C     . LYS C 3 57  ? -72.291  52.044 73.383 1.00 21.31  ? 57  LYS A C     1 
ATOM   925  O O     . LYS C 3 57  ? -72.953  51.550 72.468 1.00 29.09  ? 57  LYS A O     1 
ATOM   926  C CB    . LYS C 3 57  ? -70.085  50.896 73.356 1.00 18.05  ? 57  LYS A CB    1 
ATOM   927  C CG    . LYS C 3 57  ? -69.269  52.110 72.978 1.00 32.92  ? 57  LYS A CG    1 
ATOM   928  C CD    . LYS C 3 57  ? -68.373  51.809 71.789 1.00 53.02  ? 57  LYS A CD    1 
ATOM   929  C CE    . LYS C 3 57  ? -66.943  52.271 72.022 1.00 64.00  ? 57  LYS A CE    1 
ATOM   930  N NZ    . LYS C 3 57  ? -66.046  51.856 70.907 1.00 74.05  ? 57  LYS A NZ    1 
ATOM   931  N N     . TYR C 3 58  ? -72.382  53.315 73.745 1.00 19.84  ? 58  TYR A N     1 
ATOM   932  C CA    . TYR C 3 58  ? -73.256  54.238 73.048 1.00 16.89  ? 58  TYR A CA    1 
ATOM   933  C C     . TYR C 3 58  ? -72.381  55.058 72.129 1.00 16.54  ? 58  TYR A C     1 
ATOM   934  O O     . TYR C 3 58  ? -71.337  55.559 72.544 1.00 22.72  ? 58  TYR A O     1 
ATOM   935  C CB    . TYR C 3 58  ? -73.937  55.197 74.022 1.00 7.81   ? 58  TYR A CB    1 
ATOM   936  C CG    . TYR C 3 58  ? -75.076  54.612 74.815 1.00 18.58  ? 58  TYR A CG    1 
ATOM   937  C CD1   . TYR C 3 58  ? -74.839  53.919 76.005 1.00 11.44  ? 58  TYR A CD1   1 
ATOM   938  C CD2   . TYR C 3 58  ? -76.398  54.780 74.400 1.00 14.15  ? 58  TYR A CD2   1 
ATOM   939  C CE1   . TYR C 3 58  ? -75.895  53.410 76.764 1.00 13.74  ? 58  TYR A CE1   1 
ATOM   940  C CE2   . TYR C 3 58  ? -77.460  54.275 75.154 1.00 19.14  ? 58  TYR A CE2   1 
ATOM   941  C CZ    . TYR C 3 58  ? -77.199  53.594 76.332 1.00 16.23  ? 58  TYR A CZ    1 
ATOM   942  O OH    . TYR C 3 58  ? -78.238  53.107 77.081 1.00 21.28  ? 58  TYR A OH    1 
ATOM   943  N N     . THR C 3 59  ? -72.790  55.183 70.878 1.00 13.05  ? 59  THR A N     1 
ATOM   944  C CA    . THR C 3 59  ? -72.044  56.002 69.948 1.00 14.81  ? 59  THR A CA    1 
ATOM   945  C C     . THR C 3 59  ? -73.001  57.099 69.505 1.00 19.40  ? 59  THR A C     1 
ATOM   946  O O     . THR C 3 59  ? -74.036  56.838 68.885 1.00 23.34  ? 59  THR A O     1 
ATOM   947  C CB    . THR C 3 59  ? -71.569  55.204 68.745 1.00 16.58  ? 59  THR A CB    1 
ATOM   948  O OG1   . THR C 3 59  ? -70.566  54.270 69.157 1.00 15.65  ? 59  THR A OG1   1 
ATOM   949  C CG2   . THR C 3 59  ? -70.975  56.135 67.716 1.00 16.48  ? 59  THR A CG2   1 
ATOM   950  N N     . ILE C 3 60  ? -72.660  58.328 69.860 1.00 10.28  ? 60  ILE A N     1 
ATOM   951  C CA    . ILE C 3 60  ? -73.479  59.478 69.531 1.00 15.76  ? 60  ILE A CA    1 
ATOM   952  C C     . ILE C 3 60  ? -72.664  60.409 68.653 1.00 15.69  ? 60  ILE A C     1 
ATOM   953  O O     . ILE C 3 60  ? -71.488  60.651 68.921 1.00 20.05  ? 60  ILE A O     1 
ATOM   954  C CB    . ILE C 3 60  ? -73.899  60.227 70.820 1.00 10.21  ? 60  ILE A CB    1 
ATOM   955  C CG1   . ILE C 3 60  ? -74.824  59.341 71.642 1.00 15.87  ? 60  ILE A CG1   1 
ATOM   956  C CG2   . ILE C 3 60  ? -74.607  61.528 70.490 1.00 13.01  ? 60  ILE A CG2   1 
ATOM   957  C CD1   . ILE C 3 60  ? -74.465  59.302 73.091 1.00 11.25  ? 60  ILE A CD1   1 
ATOM   958  N N     . LYS C 3 61  ? -73.286  60.919 67.597 1.00 24.77  ? 61  LYS A N     1 
ATOM   959  C CA    . LYS C 3 61  ? -72.615  61.846 66.694 1.00 19.76  ? 61  LYS A CA    1 
ATOM   960  C C     . LYS C 3 61  ? -73.521  63.045 66.430 1.00 17.89  ? 61  LYS A C     1 
ATOM   961  O O     . LYS C 3 61  ? -74.746  62.914 66.335 1.00 25.15  ? 61  LYS A O     1 
ATOM   962  C CB    . LYS C 3 61  ? -72.271  61.166 65.360 1.00 18.95  ? 61  LYS A CB    1 
ATOM   963  C CG    . LYS C 3 61  ? -71.134  60.149 65.429 1.00 34.03  ? 61  LYS A CG    1 
ATOM   964  C CD    . LYS C 3 61  ? -70.734  59.677 64.036 1.00 54.45  ? 61  LYS A CD    1 
ATOM   965  C CE    . LYS C 3 61  ? -69.703  58.552 64.085 1.00 62.51  ? 61  LYS A CE    1 
ATOM   966  N NZ    . LYS C 3 61  ? -69.134  58.245 62.735 1.00 80.57  ? 61  LYS A NZ    1 
ATOM   967  N N     . VAL C 3 62  ? -72.908  64.217 66.334 1.00 17.88  ? 62  VAL A N     1 
ATOM   968  C CA    . VAL C 3 62  ? -73.629  65.444 66.048 1.00 16.83  ? 62  VAL A CA    1 
ATOM   969  C C     . VAL C 3 62  ? -72.852  66.201 64.972 1.00 19.72  ? 62  VAL A C     1 
ATOM   970  O O     . VAL C 3 62  ? -71.624  66.274 65.028 1.00 21.87  ? 62  VAL A O     1 
ATOM   971  C CB    . VAL C 3 62  ? -73.757  66.333 67.295 1.00 17.57  ? 62  VAL A CB    1 
ATOM   972  C CG1   . VAL C 3 62  ? -74.515  67.590 66.933 1.00 12.29  ? 62  VAL A CG1   1 
ATOM   973  C CG2   . VAL C 3 62  ? -74.483  65.581 68.414 1.00 11.83  ? 62  VAL A CG2   1 
ATOM   974  N N     . GLU C 3 63  ? -73.564  66.739 63.984 1.00 24.48  ? 63  GLU A N     1 
ATOM   975  C CA    . GLU C 3 63  ? -72.938  67.493 62.898 1.00 13.70  ? 63  GLU A CA    1 
ATOM   976  C C     . GLU C 3 63  ? -73.535  68.889 62.870 1.00 21.78  ? 63  GLU A C     1 
ATOM   977  O O     . GLU C 3 63  ? -74.736  69.047 62.642 1.00 24.46  ? 63  GLU A O     1 
ATOM   978  C CB    . GLU C 3 63  ? -73.209  66.820 61.554 1.00 18.64  ? 63  GLU A CB    1 
ATOM   979  C CG    . GLU C 3 63  ? -72.191  65.768 61.165 1.00 26.52  ? 63  GLU A CG    1 
ATOM   980  C CD    . GLU C 3 63  ? -72.484  65.154 59.811 1.00 30.97  ? 63  GLU A CD    1 
ATOM   981  O OE1   . GLU C 3 63  ? -73.145  65.829 58.989 1.00 30.11  ? 63  GLU A OE1   1 
ATOM   982  O OE2   . GLU C 3 63  ? -72.053  64.001 59.572 1.00 40.34  ? 63  GLU A OE2   1 
ATOM   983  N N     . VAL C 3 64  ? -72.710  69.900 63.119 1.00 20.94  ? 64  VAL A N     1 
ATOM   984  C CA    . VAL C 3 64  ? -73.198  71.273 63.096 1.00 20.05  ? 64  VAL A CA    1 
ATOM   985  C C     . VAL C 3 64  ? -72.696  71.948 61.832 1.00 24.05  ? 64  VAL A C     1 
ATOM   986  O O     . VAL C 3 64  ? -71.494  72.132 61.646 1.00 22.96  ? 64  VAL A O     1 
ATOM   987  C CB    . VAL C 3 64  ? -72.713  72.072 64.305 1.00 21.21  ? 64  VAL A CB    1 
ATOM   988  C CG1   . VAL C 3 64  ? -73.095  73.530 64.136 1.00 12.35  ? 64  VAL A CG1   1 
ATOM   989  C CG2   . VAL C 3 64  ? -73.329  71.507 65.572 1.00 12.13  ? 64  VAL A CG2   1 
ATOM   990  N N     . PRO C 3 65  ? -73.618  72.323 60.939 1.00 24.00  ? 65  PRO A N     1 
ATOM   991  C CA    . PRO C 3 65  ? -73.236  72.974 59.690 1.00 14.24  ? 65  PRO A CA    1 
ATOM   992  C C     . PRO C 3 65  ? -73.198  74.495 59.733 1.00 19.59  ? 65  PRO A C     1 
ATOM   993  O O     . PRO C 3 65  ? -73.895  75.134 60.529 1.00 25.26  ? 65  PRO A O     1 
ATOM   994  C CB    . PRO C 3 65  ? -74.301  72.494 58.727 1.00 13.79  ? 65  PRO A CB    1 
ATOM   995  C CG    . PRO C 3 65  ? -75.546  72.448 59.606 1.00 11.74  ? 65  PRO A CG    1 
ATOM   996  C CD    . PRO C 3 65  ? -75.080  72.135 61.018 1.00 19.29  ? 65  PRO A CD    1 
ATOM   997  N N     . LYS C 3 66  ? -72.362  75.056 58.865 1.00 22.22  ? 66  LYS A N     1 
ATOM   998  C CA    . LYS C 3 66  ? -72.247  76.496 58.688 1.00 19.25  ? 66  LYS A CA    1 
ATOM   999  C C     . LYS C 3 66  ? -72.934  76.669 57.323 1.00 28.99  ? 66  LYS A C     1 
ATOM   1000 O O     . LYS C 3 66  ? -72.313  76.462 56.273 1.00 21.74  ? 66  LYS A O     1 
ATOM   1001 C CB    . LYS C 3 66  ? -70.776  76.901 58.602 1.00 21.09  ? 66  LYS A CB    1 
ATOM   1002 C CG    . LYS C 3 66  ? -70.543  78.398 58.435 1.00 11.32  ? 66  LYS A CG    1 
ATOM   1003 C CD    . LYS C 3 66  ? -71.352  79.207 59.434 1.00 16.78  ? 66  LYS A CD    1 
ATOM   1004 C CE    . LYS C 3 66  ? -70.593  80.435 59.927 1.00 14.58  ? 66  LYS A CE    1 
ATOM   1005 N NZ    . LYS C 3 66  ? -71.503  81.548 60.347 1.00 25.21  ? 66  LYS A NZ    1 
ATOM   1006 N N     . VAL C 3 67  ? -74.224  77.000 57.344 1.00 23.13  ? 67  VAL A N     1 
ATOM   1007 C CA    . VAL C 3 67  ? -75.001  77.150 56.109 1.00 28.14  ? 67  VAL A CA    1 
ATOM   1008 C C     . VAL C 3 67  ? -74.528  78.264 55.190 1.00 27.45  ? 67  VAL A C     1 
ATOM   1009 O O     . VAL C 3 67  ? -74.139  79.344 55.635 1.00 31.23  ? 67  VAL A O     1 
ATOM   1010 C CB    . VAL C 3 67  ? -76.491  77.378 56.411 1.00 15.24  ? 67  VAL A CB    1 
ATOM   1011 C CG1   . VAL C 3 67  ? -77.141  76.058 56.778 1.00 31.32  ? 67  VAL A CG1   1 
ATOM   1012 C CG2   . VAL C 3 67  ? -76.642  78.370 57.552 1.00 41.85  ? 67  VAL A CG2   1 
ATOM   1013 N N     . ALA C 3 68  ? -74.585  77.997 53.893 1.00 34.51  ? 68  ALA A N     1 
ATOM   1014 C CA    . ALA C 3 68  ? -74.142  78.965 52.904 1.00 33.19  ? 68  ALA A CA    1 
ATOM   1015 C C     . ALA C 3 68  ? -74.749  78.665 51.542 1.00 36.34  ? 68  ALA A C     1 
ATOM   1016 O O     . ALA C 3 68  ? -75.171  77.541 51.278 1.00 39.03  ? 68  ALA A O     1 
ATOM   1017 C CB    . ALA C 3 68  ? -72.621  78.932 52.808 1.00 22.19  ? 68  ALA A CB    1 
ATOM   1018 N N     . THR C 3 69  ? -74.789  79.675 50.679 1.00 39.26  ? 69  THR A N     1 
ATOM   1019 C CA    . THR C 3 69  ? -75.321  79.494 49.336 1.00 35.26  ? 69  THR A CA    1 
ATOM   1020 C C     . THR C 3 69  ? -74.199  79.615 48.322 1.00 33.40  ? 69  THR A C     1 
ATOM   1021 O O     . THR C 3 69  ? -73.661  80.695 48.097 1.00 48.33  ? 69  THR A O     1 
ATOM   1022 C CB    . THR C 3 69  ? -76.381  80.532 49.002 1.00 30.55  ? 69  THR A CB    1 
ATOM   1023 O OG1   . THR C 3 69  ? -77.453  80.450 49.951 1.00 42.86  ? 69  THR A OG1   1 
ATOM   1024 C CG2   . THR C 3 69  ? -76.910  80.283 47.605 1.00 27.22  ? 69  THR A CG2   1 
ATOM   1025 N N     . GLN C 3 70  ? -73.851  78.494 47.709 1.00 39.01  ? 70  GLN A N     1 
ATOM   1026 C CA    . GLN C 3 70  ? -72.777  78.458 46.732 1.00 44.55  ? 70  GLN A CA    1 
ATOM   1027 C C     . GLN C 3 70  ? -73.293  78.551 45.303 1.00 52.05  ? 70  GLN A C     1 
ATOM   1028 O O     . GLN C 3 70  ? -74.410  78.135 45.006 1.00 57.16  ? 70  GLN A O     1 
ATOM   1029 C CB    . GLN C 3 70  ? -71.973  77.172 46.907 1.00 39.51  ? 70  GLN A CB    1 
ATOM   1030 C CG    . GLN C 3 70  ? -70.963  76.914 45.823 1.00 47.17  ? 70  GLN A CG    1 
ATOM   1031 C CD    . GLN C 3 70  ? -69.814  76.073 46.313 1.00 60.65  ? 70  GLN A CD    1 
ATOM   1032 O OE1   . GLN C 3 70  ? -69.970  74.874 46.552 1.00 66.40  ? 70  GLN A OE1   1 
ATOM   1033 N NE2   . GLN C 3 70  ? -68.646  76.694 46.470 1.00 73.33  ? 70  GLN A NE2   1 
ATOM   1034 N N     . THR C 3 71  ? -72.464  79.098 44.421 1.00 60.81  ? 71  THR A N     1 
ATOM   1035 C CA    . THR C 3 71  ? -72.817  79.246 43.019 1.00 49.42  ? 71  THR A CA    1 
ATOM   1036 C C     . THR C 3 71  ? -71.978  78.324 42.152 1.00 47.18  ? 71  THR A C     1 
ATOM   1037 O O     . THR C 3 71  ? -70.849  78.646 41.802 1.00 54.41  ? 71  THR A O     1 
ATOM   1038 C CB    . THR C 3 71  ? -72.606  80.682 42.538 1.00 31.02  ? 71  THR A CB    1 
ATOM   1039 O OG1   . THR C 3 71  ? -73.495  81.560 43.248 1.00 40.65  ? 71  THR A OG1   1 
ATOM   1040 C CG2   . THR C 3 71  ? -72.872  80.767 41.033 1.00 25.74  ? 71  THR A CG2   1 
ATOM   1041 N N     . VAL C 3 72  ? -72.547  77.174 41.813 1.00 57.78  ? 72  VAL A N     1 
ATOM   1042 C CA    . VAL C 3 72  ? -71.872  76.181 40.988 1.00 60.55  ? 72  VAL A CA    1 
ATOM   1043 C C     . VAL C 3 72  ? -72.463  76.181 39.580 1.00 68.45  ? 72  VAL A C     1 
ATOM   1044 O O     . VAL C 3 72  ? -73.654  75.914 39.399 1.00 76.47  ? 72  VAL A O     1 
ATOM   1045 C CB    . VAL C 3 72  ? -72.034  74.772 41.588 1.00 59.82  ? 72  VAL A CB    1 
ATOM   1046 C CG1   . VAL C 3 72  ? -71.182  73.780 40.821 1.00 50.66  ? 72  VAL A CG1   1 
ATOM   1047 C CG2   . VAL C 3 72  ? -71.665  74.789 43.065 1.00 59.83  ? 72  VAL A CG2   1 
ATOM   1048 N N     . GLY C 3 73  ? -71.630  76.478 38.587 1.00 61.63  ? 73  GLY A N     1 
ATOM   1049 C CA    . GLY C 3 73  ? -72.106  76.512 37.217 1.00 51.10  ? 73  GLY A CA    1 
ATOM   1050 C C     . GLY C 3 73  ? -73.118  77.618 36.965 1.00 53.63  ? 73  GLY A C     1 
ATOM   1051 O O     . GLY C 3 73  ? -74.049  77.440 36.183 1.00 59.34  ? 73  GLY A O     1 
ATOM   1052 N N     . GLY C 3 74  ? -72.943  78.757 37.631 1.00 54.83  ? 74  GLY A N     1 
ATOM   1053 C CA    . GLY C 3 74  ? -73.854  79.875 37.450 1.00 49.79  ? 74  GLY A CA    1 
ATOM   1054 C C     . GLY C 3 74  ? -75.174  79.723 38.178 1.00 52.32  ? 74  GLY A C     1 
ATOM   1055 O O     . GLY C 3 74  ? -75.983  80.657 38.207 1.00 55.54  ? 74  GLY A O     1 
ATOM   1056 N N     . VAL C 3 75  ? -75.383  78.549 38.770 1.00 51.26  ? 75  VAL A N     1 
ATOM   1057 C CA    . VAL C 3 75  ? -76.608  78.240 39.510 1.00 47.80  ? 75  VAL A CA    1 
ATOM   1058 C C     . VAL C 3 75  ? -76.383  78.279 41.024 1.00 46.33  ? 75  VAL A C     1 
ATOM   1059 O O     . VAL C 3 75  ? -75.344  77.835 41.514 1.00 39.79  ? 75  VAL A O     1 
ATOM   1060 C CB    . VAL C 3 75  ? -77.128  76.841 39.138 1.00 36.27  ? 75  VAL A CB    1 
ATOM   1061 C CG1   . VAL C 3 75  ? -78.472  76.603 39.783 1.00 40.64  ? 75  VAL A CG1   1 
ATOM   1062 C CG2   . VAL C 3 75  ? -77.231  76.712 37.631 1.00 31.62  ? 75  VAL A CG2   1 
ATOM   1063 N N     . GLU C 3 76  ? -77.362  78.797 41.761 1.00 39.09  ? 76  GLU A N     1 
ATOM   1064 C CA    . GLU C 3 76  ? -77.255  78.883 43.216 1.00 38.66  ? 76  GLU A CA    1 
ATOM   1065 C C     . GLU C 3 76  ? -77.801  77.651 43.946 1.00 38.24  ? 76  GLU A C     1 
ATOM   1066 O O     . GLU C 3 76  ? -78.945  77.248 43.736 1.00 48.34  ? 76  GLU A O     1 
ATOM   1067 C CB    . GLU C 3 76  ? -77.990  80.116 43.711 1.00 45.61  ? 76  GLU A CB    1 
ATOM   1068 C CG    . GLU C 3 76  ? -77.176  81.380 43.650 1.00 62.47  ? 76  GLU A CG    1 
ATOM   1069 C CD    . GLU C 3 76  ? -77.950  82.563 44.185 1.00 88.99  ? 76  GLU A CD    1 
ATOM   1070 O OE1   . GLU C 3 76  ? -79.113  82.367 44.614 1.00 86.99  ? 76  GLU A OE1   1 
ATOM   1071 O OE2   . GLU C 3 76  ? -77.400  83.685 44.178 1.00 100.00 ? 76  GLU A OE2   1 
ATOM   1072 N N     . LEU C 3 77  ? -76.983  77.078 44.826 1.00 38.94  ? 77  LEU A N     1 
ATOM   1073 C CA    . LEU C 3 77  ? -77.364  75.887 45.582 1.00 27.38  ? 77  LEU A CA    1 
ATOM   1074 C C     . LEU C 3 77  ? -77.205  76.005 47.094 1.00 32.84  ? 77  LEU A C     1 
ATOM   1075 O O     . LEU C 3 77  ? -76.250  76.606 47.583 1.00 34.77  ? 77  LEU A O     1 
ATOM   1076 C CB    . LEU C 3 77  ? -76.533  74.695 45.124 1.00 12.88  ? 77  LEU A CB    1 
ATOM   1077 C CG    . LEU C 3 77  ? -76.714  74.256 43.678 1.00 21.94  ? 77  LEU A CG    1 
ATOM   1078 C CD1   . LEU C 3 77  ? -75.686  73.205 43.350 1.00 12.97  ? 77  LEU A CD1   1 
ATOM   1079 C CD2   . LEU C 3 77  ? -78.110  73.703 43.481 1.00 25.53  ? 77  LEU A CD2   1 
ATOM   1080 N N     . PRO C 3 78  ? -78.143  75.416 47.856 1.00 34.17  ? 78  PRO A N     1 
ATOM   1081 C CA    . PRO C 3 78  ? -78.062  75.468 49.316 1.00 29.53  ? 78  PRO A CA    1 
ATOM   1082 C C     . PRO C 3 78  ? -76.997  74.443 49.704 1.00 32.09  ? 78  PRO A C     1 
ATOM   1083 O O     . PRO C 3 78  ? -77.122  73.254 49.400 1.00 35.40  ? 78  PRO A O     1 
ATOM   1084 C CB    . PRO C 3 78  ? -79.455  75.051 49.764 1.00 18.35  ? 78  PRO A CB    1 
ATOM   1085 C CG    . PRO C 3 78  ? -79.912  74.130 48.693 1.00 36.55  ? 78  PRO A CG    1 
ATOM   1086 C CD    . PRO C 3 78  ? -79.321  74.656 47.404 1.00 37.28  ? 78  PRO A CD    1 
ATOM   1087 N N     . VAL C 3 79  ? -75.944  74.908 50.361 1.00 25.31  ? 79  VAL A N     1 
ATOM   1088 C CA    . VAL C 3 79  ? -74.852  74.032 50.741 1.00 23.64  ? 79  VAL A CA    1 
ATOM   1089 C C     . VAL C 3 79  ? -74.297  74.380 52.134 1.00 23.41  ? 79  VAL A C     1 
ATOM   1090 O O     . VAL C 3 79  ? -74.808  75.273 52.806 1.00 27.20  ? 79  VAL A O     1 
ATOM   1091 C CB    . VAL C 3 79  ? -73.744  74.135 49.675 1.00 21.26  ? 79  VAL A CB    1 
ATOM   1092 C CG1   . VAL C 3 79  ? -73.013  75.458 49.827 1.00 12.98  ? 79  VAL A CG1   1 
ATOM   1093 C CG2   . VAL C 3 79  ? -72.791  72.958 49.790 1.00 54.82  ? 79  VAL A CG2   1 
ATOM   1094 N N     . ALA C 3 80  ? -73.269  73.660 52.577 1.00 26.49  ? 80  ALA A N     1 
ATOM   1095 C CA    . ALA C 3 80  ? -72.657  73.934 53.878 1.00 21.28  ? 80  ALA A CA    1 
ATOM   1096 C C     . ALA C 3 80  ? -71.198  74.337 53.670 1.00 26.98  ? 80  ALA A C     1 
ATOM   1097 O O     . ALA C 3 80  ? -70.414  73.579 53.088 1.00 24.66  ? 80  ALA A O     1 
ATOM   1098 C CB    . ALA C 3 80  ? -72.734  72.708 54.767 1.00 16.08  ? 80  ALA A CB    1 
ATOM   1099 N N     . ALA C 3 81  ? -70.837  75.530 54.135 1.00 14.22  ? 81  ALA A N     1 
ATOM   1100 C CA    . ALA C 3 81  ? -69.468  76.013 53.984 1.00 18.80  ? 81  ALA A CA    1 
ATOM   1101 C C     . ALA C 3 81  ? -68.499  75.044 54.657 1.00 22.32  ? 81  ALA A C     1 
ATOM   1102 O O     . ALA C 3 81  ? -67.395  74.804 54.173 1.00 29.14  ? 81  ALA A O     1 
ATOM   1103 C CB    . ALA C 3 81  ? -69.336  77.395 54.587 1.00 21.42  ? 81  ALA A CB    1 
ATOM   1104 N N     . TRP C 3 82  ? -68.924  74.506 55.792 1.00 32.39  ? 82  TRP A N     1 
ATOM   1105 C CA    . TRP C 3 82  ? -68.143  73.535 56.542 1.00 19.68  ? 82  TRP A CA    1 
ATOM   1106 C C     . TRP C 3 82  ? -69.029  72.976 57.636 1.00 21.42  ? 82  TRP A C     1 
ATOM   1107 O O     . TRP C 3 82  ? -70.131  73.484 57.879 1.00 29.04  ? 82  TRP A O     1 
ATOM   1108 C CB    . TRP C 3 82  ? -66.866  74.153 57.144 1.00 16.22  ? 82  TRP A CB    1 
ATOM   1109 C CG    . TRP C 3 82  ? -67.036  75.462 57.842 1.00 23.53  ? 82  TRP A CG    1 
ATOM   1110 C CD1   . TRP C 3 82  ? -66.754  76.695 57.338 1.00 23.97  ? 82  TRP A CD1   1 
ATOM   1111 C CD2   . TRP C 3 82  ? -67.514  75.673 59.179 1.00 22.79  ? 82  TRP A CD2   1 
ATOM   1112 N NE1   . TRP C 3 82  ? -67.026  77.664 58.274 1.00 32.73  ? 82  TRP A NE1   1 
ATOM   1113 C CE2   . TRP C 3 82  ? -67.494  77.065 59.414 1.00 24.70  ? 82  TRP A CE2   1 
ATOM   1114 C CE3   . TRP C 3 82  ? -67.956  74.822 60.199 1.00 21.93  ? 82  TRP A CE3   1 
ATOM   1115 C CZ2   . TRP C 3 82  ? -67.900  77.629 60.629 1.00 28.28  ? 82  TRP A CZ2   1 
ATOM   1116 C CZ3   . TRP C 3 82  ? -68.361  75.382 61.408 1.00 31.45  ? 82  TRP A CZ3   1 
ATOM   1117 C CH2   . TRP C 3 82  ? -68.329  76.775 61.611 1.00 24.35  ? 82  TRP A CH2   1 
ATOM   1118 N N     . ARG C 3 83  ? -68.545  71.926 58.288 1.00 23.50  ? 83  ARG A N     1 
ATOM   1119 C CA    . ARG C 3 83  ? -69.287  71.267 59.351 1.00 22.53  ? 83  ARG A CA    1 
ATOM   1120 C C     . ARG C 3 83  ? -68.400  70.986 60.562 1.00 20.23  ? 83  ARG A C     1 
ATOM   1121 O O     . ARG C 3 83  ? -67.206  70.715 60.433 1.00 26.36  ? 83  ARG A O     1 
ATOM   1122 C CB    . ARG C 3 83  ? -69.857  69.936 58.838 1.00 14.95  ? 83  ARG A CB    1 
ATOM   1123 C CG    . ARG C 3 83  ? -71.257  70.019 58.274 1.00 27.43  ? 83  ARG A CG    1 
ATOM   1124 C CD    . ARG C 3 83  ? -71.645  68.769 57.470 1.00 14.86  ? 83  ARG A CD    1 
ATOM   1125 N NE    . ARG C 3 83  ? -72.852  69.032 56.686 1.00 30.26  ? 83  ARG A NE    1 
ATOM   1126 C CZ    . ARG C 3 83  ? -74.090  68.963 57.172 1.00 30.61  ? 83  ARG A CZ    1 
ATOM   1127 N NH1   . ARG C 3 83  ? -74.292  68.634 58.441 1.00 28.89  ? 83  ARG A NH1   1 
ATOM   1128 N NH2   . ARG C 3 83  ? -75.129  69.259 56.401 1.00 47.66  ? 83  ARG A NH2   1 
ATOM   1129 N N     . SER C 3 84  ? -68.990  71.066 61.745 1.00 25.80  ? 84  SER A N     1 
ATOM   1130 C CA    . SER C 3 84  ? -68.273  70.753 62.965 1.00 14.61  ? 84  SER A CA    1 
ATOM   1131 C C     . SER C 3 84  ? -68.753  69.346 63.320 1.00 19.67  ? 84  SER A C     1 
ATOM   1132 O O     . SER C 3 84  ? -69.950  69.052 63.235 1.00 25.73  ? 84  SER A O     1 
ATOM   1133 C CB    . SER C 3 84  ? -68.641  71.735 64.065 1.00 16.00  ? 84  SER A CB    1 
ATOM   1134 O OG    . SER C 3 84  ? -67.742  71.599 65.143 1.00 38.35  ? 84  SER A OG    1 
ATOM   1135 N N     . TYR C 3 85  ? -67.832  68.470 63.702 1.00 25.38  ? 85  TYR A N     1 
ATOM   1136 C CA    . TYR C 3 85  ? -68.196  67.094 64.029 1.00 14.41  ? 85  TYR A CA    1 
ATOM   1137 C C     . TYR C 3 85  ? -67.955  66.713 65.476 1.00 17.87  ? 85  TYR A C     1 
ATOM   1138 O O     . TYR C 3 85  ? -66.822  66.774 65.959 1.00 29.13  ? 85  TYR A O     1 
ATOM   1139 C CB    . TYR C 3 85  ? -67.415  66.120 63.150 1.00 19.50  ? 85  TYR A CB    1 
ATOM   1140 C CG    . TYR C 3 85  ? -67.673  66.266 61.674 1.00 21.00  ? 85  TYR A CG    1 
ATOM   1141 C CD1   . TYR C 3 85  ? -66.926  67.148 60.903 1.00 25.76  ? 85  TYR A CD1   1 
ATOM   1142 C CD2   . TYR C 3 85  ? -68.664  65.519 61.044 1.00 25.32  ? 85  TYR A CD2   1 
ATOM   1143 C CE1   . TYR C 3 85  ? -67.158  67.284 59.544 1.00 40.17  ? 85  TYR A CE1   1 
ATOM   1144 C CE2   . TYR C 3 85  ? -68.905  65.648 59.684 1.00 31.43  ? 85  TYR A CE2   1 
ATOM   1145 C CZ    . TYR C 3 85  ? -68.148  66.533 58.941 1.00 31.40  ? 85  TYR A CZ    1 
ATOM   1146 O OH    . TYR C 3 85  ? -68.382  66.676 57.594 1.00 55.49  ? 85  TYR A OH    1 
ATOM   1147 N N     . LEU C 3 86  ? -69.021  66.318 66.166 1.00 20.73  ? 86  LEU A N     1 
ATOM   1148 C CA    . LEU C 3 86  ? -68.901  65.877 67.550 1.00 23.90  ? 86  LEU A CA    1 
ATOM   1149 C C     . LEU C 3 86  ? -69.033  64.369 67.536 1.00 18.74  ? 86  LEU A C     1 
ATOM   1150 O O     . LEU C 3 86  ? -70.016  63.823 67.043 1.00 31.57  ? 86  LEU A O     1 
ATOM   1151 C CB    . LEU C 3 86  ? -70.004  66.451 68.441 1.00 20.65  ? 86  LEU A CB    1 
ATOM   1152 C CG    . LEU C 3 86  ? -70.078  65.778 69.826 1.00 26.41  ? 86  LEU A CG    1 
ATOM   1153 C CD1   . LEU C 3 86  ? -68.720  65.870 70.524 1.00 33.74  ? 86  LEU A CD1   1 
ATOM   1154 C CD2   . LEU C 3 86  ? -71.147  66.442 70.676 1.00 23.51  ? 86  LEU A CD2   1 
ATOM   1155 N N     . ASN C 3 87  ? -68.035  63.689 68.066 1.00 18.30  ? 87  ASN A N     1 
ATOM   1156 C CA    . ASN C 3 87  ? -68.085  62.245 68.100 1.00 18.59  ? 87  ASN A CA    1 
ATOM   1157 C C     . ASN C 3 87  ? -67.882  61.817 69.539 1.00 22.83  ? 87  ASN A C     1 
ATOM   1158 O O     . ASN C 3 87  ? -66.840  62.099 70.132 1.00 25.81  ? 87  ASN A O     1 
ATOM   1159 C CB    . ASN C 3 87  ? -66.988  61.657 67.208 1.00 23.34  ? 87  ASN A CB    1 
ATOM   1160 C CG    A ASN C 3 87  ? -67.126  62.080 65.741 0.55 31.94  ? 87  ASN A CG    1 
ATOM   1161 C CG    B ASN C 3 87  ? -67.193  60.192 66.930 0.45 27.09  ? 87  ASN A CG    1 
ATOM   1162 O OD1   A ASN C 3 87  ? -68.195  61.958 65.145 0.55 36.53  ? 87  ASN A OD1   1 
ATOM   1163 O OD1   B ASN C 3 87  ? -67.709  59.460 67.769 0.45 36.53  ? 87  ASN A OD1   1 
ATOM   1164 N ND2   A ASN C 3 87  ? -66.035  62.580 65.160 0.55 39.33  ? 87  ASN A ND2   1 
ATOM   1165 N ND2   B ASN C 3 87  ? -66.791  59.752 65.745 0.45 51.97  ? 87  ASN A ND2   1 
ATOM   1166 N N     . MET C 3 88  ? -68.888  61.173 70.122 1.00 8.76   ? 88  MET A N     1 
ATOM   1167 C CA    . MET C 3 88  ? -68.736  60.709 71.484 1.00 16.92  ? 88  MET A CA    1 
ATOM   1168 C C     . MET C 3 88  ? -69.122  59.246 71.690 1.00 11.77  ? 88  MET A C     1 
ATOM   1169 O O     . MET C 3 88  ? -70.119  58.770 71.152 1.00 24.81  ? 88  MET A O     1 
ATOM   1170 C CB    . MET C 3 88  ? -69.487  61.632 72.438 1.00 17.81  ? 88  MET A CB    1 
ATOM   1171 C CG    . MET C 3 88  ? -70.946  61.374 72.618 1.00 29.60  ? 88  MET A CG    1 
ATOM   1172 S SD    . MET C 3 88  ? -71.569  62.596 73.793 1.00 44.00  ? 88  MET A SD    1 
ATOM   1173 C CE    . MET C 3 88  ? -71.222  64.073 72.909 1.00 29.01  ? 88  MET A CE    1 
ATOM   1174 N N     . GLU C 3 89  ? -68.281  58.534 72.441 1.00 21.07  ? 89  GLU A N     1 
ATOM   1175 C CA    . GLU C 3 89  ? -68.481  57.119 72.759 1.00 16.19  ? 89  GLU A CA    1 
ATOM   1176 C C     . GLU C 3 89  ? -68.553  56.955 74.264 1.00 18.83  ? 89  GLU A C     1 
ATOM   1177 O O     . GLU C 3 89  ? -67.661  57.391 74.990 1.00 24.67  ? 89  GLU A O     1 
ATOM   1178 C CB    . GLU C 3 89  ? -67.319  56.280 72.258 1.00 21.77  ? 89  GLU A CB    1 
ATOM   1179 C CG    . GLU C 3 89  ? -67.037  56.408 70.791 1.00 52.24  ? 89  GLU A CG    1 
ATOM   1180 C CD    . GLU C 3 89  ? -66.261  55.225 70.280 1.00 65.09  ? 89  GLU A CD    1 
ATOM   1181 O OE1   . GLU C 3 89  ? -65.406  54.713 71.040 1.00 69.74  ? 89  GLU A OE1   1 
ATOM   1182 O OE2   . GLU C 3 89  ? -66.509  54.809 69.128 1.00 82.88  ? 89  GLU A OE2   1 
ATOM   1183 N N     . LEU C 3 90  ? -69.609  56.308 74.730 1.00 20.49  ? 90  LEU A N     1 
ATOM   1184 C CA    . LEU C 3 90  ? -69.795  56.099 76.153 1.00 20.57  ? 90  LEU A CA    1 
ATOM   1185 C C     . LEU C 3 90  ? -69.856  54.602 76.436 1.00 18.84  ? 90  LEU A C     1 
ATOM   1186 O O     . LEU C 3 90  ? -70.728  53.901 75.919 1.00 24.52  ? 90  LEU A O     1 
ATOM   1187 C CB    . LEU C 3 90  ? -71.086  56.792 76.589 1.00 11.87  ? 90  LEU A CB    1 
ATOM   1188 C CG    . LEU C 3 90  ? -71.496  56.658 78.047 1.00 21.96  ? 90  LEU A CG    1 
ATOM   1189 C CD1   . LEU C 3 90  ? -70.410  57.211 78.962 1.00 23.16  ? 90  LEU A CD1   1 
ATOM   1190 C CD2   . LEU C 3 90  ? -72.796  57.400 78.235 1.00 21.94  ? 90  LEU A CD2   1 
ATOM   1191 N N     . THR C 3 91  ? -68.918  54.111 77.239 1.00 18.65  ? 91  THR A N     1 
ATOM   1192 C CA    . THR C 3 91  ? -68.868  52.689 77.584 1.00 18.04  ? 91  THR A CA    1 
ATOM   1193 C C     . THR C 3 91  ? -69.287  52.490 79.031 1.00 17.17  ? 91  THR A C     1 
ATOM   1194 O O     . THR C 3 91  ? -68.611  52.951 79.946 1.00 25.74  ? 91  THR A O     1 
ATOM   1195 C CB    . THR C 3 91  ? -67.462  52.129 77.412 1.00 16.70  ? 91  THR A CB    1 
ATOM   1196 O OG1   . THR C 3 91  ? -67.047  52.304 76.057 1.00 28.30  ? 91  THR A OG1   1 
ATOM   1197 C CG2   . THR C 3 91  ? -67.439  50.658 77.738 1.00 15.99  ? 91  THR A CG2   1 
ATOM   1198 N N     . ILE C 3 92  ? -70.396  51.786 79.228 1.00 20.16  ? 92  ILE A N     1 
ATOM   1199 C CA    . ILE C 3 92  ? -70.950  51.552 80.557 1.00 13.37  ? 92  ILE A CA    1 
ATOM   1200 C C     . ILE C 3 92  ? -70.980  50.068 80.910 1.00 16.46  ? 92  ILE A C     1 
ATOM   1201 O O     . ILE C 3 92  ? -71.435  49.251 80.113 1.00 30.29  ? 92  ILE A O     1 
ATOM   1202 C CB    . ILE C 3 92  ? -72.394  52.116 80.619 1.00 9.64   ? 92  ILE A CB    1 
ATOM   1203 C CG1   . ILE C 3 92  ? -72.389  53.571 80.149 1.00 14.04  ? 92  ILE A CG1   1 
ATOM   1204 C CG2   . ILE C 3 92  ? -72.956  52.005 82.026 1.00 16.38  ? 92  ILE A CG2   1 
ATOM   1205 C CD1   . ILE C 3 92  ? -73.758  54.170 79.960 1.00 17.58  ? 92  ILE A CD1   1 
ATOM   1206 N N     . PRO C 3 93  ? -70.477  49.696 82.101 1.00 15.17  ? 93  PRO A N     1 
ATOM   1207 C CA    . PRO C 3 93  ? -70.496  48.275 82.480 1.00 14.26  ? 93  PRO A CA    1 
ATOM   1208 C C     . PRO C 3 93  ? -71.932  47.805 82.735 1.00 17.34  ? 93  PRO A C     1 
ATOM   1209 O O     . PRO C 3 93  ? -72.758  48.570 83.231 1.00 28.58  ? 93  PRO A O     1 
ATOM   1210 C CB    . PRO C 3 93  ? -69.631  48.216 83.740 1.00 9.90   ? 93  PRO A CB    1 
ATOM   1211 C CG    . PRO C 3 93  ? -69.660  49.596 84.298 1.00 9.13   ? 93  PRO A CG    1 
ATOM   1212 C CD    . PRO C 3 93  ? -69.857  50.544 83.136 1.00 13.76  ? 93  PRO A CD    1 
ATOM   1213 N N     . ILE C 3 94  ? -72.226  46.553 82.397 1.00 16.67  ? 94  ILE A N     1 
ATOM   1214 C CA    . ILE C 3 94  ? -73.572  46.002 82.573 1.00 13.27  ? 94  ILE A CA    1 
ATOM   1215 C C     . ILE C 3 94  ? -74.039  45.975 84.025 1.00 21.08  ? 94  ILE A C     1 
ATOM   1216 O O     . ILE C 3 94  ? -75.227  45.791 84.288 1.00 22.45  ? 94  ILE A O     1 
ATOM   1217 C CB    . ILE C 3 94  ? -73.671  44.559 82.025 1.00 15.58  ? 94  ILE A CB    1 
ATOM   1218 C CG1   . ILE C 3 94  ? -72.616  43.681 82.686 1.00 16.45  ? 94  ILE A CG1   1 
ATOM   1219 C CG2   . ILE C 3 94  ? -73.450  44.536 80.526 1.00 3.07   ? 94  ILE A CG2   1 
ATOM   1220 C CD1   . ILE C 3 94  ? -72.838  42.235 82.436 1.00 2.00   ? 94  ILE A CD1   1 
ATOM   1221 N N     . PHE C 3 95  ? -73.106  46.151 84.960 1.00 17.52  ? 95  PHE A N     1 
ATOM   1222 C CA    . PHE C 3 95  ? -73.435  46.142 86.384 1.00 18.90  ? 95  PHE A CA    1 
ATOM   1223 C C     . PHE C 3 95  ? -73.927  47.495 86.870 1.00 20.92  ? 95  PHE A C     1 
ATOM   1224 O O     . PHE C 3 95  ? -74.259  47.666 88.043 1.00 23.57  ? 95  PHE A O     1 
ATOM   1225 C CB    . PHE C 3 95  ? -72.214  45.718 87.195 1.00 12.49  ? 95  PHE A CB    1 
ATOM   1226 C CG    . PHE C 3 95  ? -71.557  44.493 86.667 1.00 19.12  ? 95  PHE A CG    1 
ATOM   1227 C CD1   . PHE C 3 95  ? -72.147  43.247 86.846 1.00 14.58  ? 95  PHE A CD1   1 
ATOM   1228 C CD2   . PHE C 3 95  ? -70.388  44.584 85.926 1.00 17.04  ? 95  PHE A CD2   1 
ATOM   1229 C CE1   . PHE C 3 95  ? -71.585  42.112 86.288 1.00 15.15  ? 95  PHE A CE1   1 
ATOM   1230 C CE2   . PHE C 3 95  ? -69.818  43.453 85.363 1.00 15.06  ? 95  PHE A CE2   1 
ATOM   1231 C CZ    . PHE C 3 95  ? -70.417  42.212 85.541 1.00 12.57  ? 95  PHE A CZ    1 
ATOM   1232 N N     . ALA C 3 96  ? -73.970  48.461 85.965 1.00 17.15  ? 96  ALA A N     1 
ATOM   1233 C CA    . ALA C 3 96  ? -74.427  49.789 86.325 1.00 16.22  ? 96  ALA A CA    1 
ATOM   1234 C C     . ALA C 3 96  ? -75.944  49.793 86.439 1.00 17.37  ? 96  ALA A C     1 
ATOM   1235 O O     . ALA C 3 96  ? -76.656  49.363 85.529 1.00 21.05  ? 96  ALA A O     1 
ATOM   1236 C CB    . ALA C 3 96  ? -73.971  50.805 85.279 1.00 4.83   ? 96  ALA A CB    1 
ATOM   1237 N N     . THR C 3 97  ? -76.432  50.268 87.574 1.00 18.06  ? 97  THR A N     1 
ATOM   1238 C CA    . THR C 3 97  ? -77.862  50.352 87.813 1.00 11.09  ? 97  THR A CA    1 
ATOM   1239 C C     . THR C 3 97  ? -78.345  51.626 87.137 1.00 19.04  ? 97  THR A C     1 
ATOM   1240 O O     . THR C 3 97  ? -77.546  52.367 86.556 1.00 27.64  ? 97  THR A O     1 
ATOM   1241 C CB    . THR C 3 97  ? -78.143  50.465 89.295 1.00 10.84  ? 97  THR A CB    1 
ATOM   1242 O OG1   . THR C 3 97  ? -77.653  51.727 89.760 1.00 16.74  ? 97  THR A OG1   1 
ATOM   1243 C CG2   . THR C 3 97  ? -77.441  49.351 90.053 1.00 5.45   ? 97  THR A CG2   1 
ATOM   1244 N N     . ASN C 3 98  ? -79.644  51.892 87.217 1.00 13.84  ? 98  ASN A N     1 
ATOM   1245 C CA    . ASN C 3 98  ? -80.192  53.093 86.600 1.00 6.97   ? 98  ASN A CA    1 
ATOM   1246 C C     . ASN C 3 98  ? -79.648  54.337 87.309 1.00 19.17  ? 98  ASN A C     1 
ATOM   1247 O O     . ASN C 3 98  ? -79.353  55.349 86.670 1.00 24.82  ? 98  ASN A O     1 
ATOM   1248 C CB    . ASN C 3 98  ? -81.719  53.078 86.665 1.00 20.81  ? 98  ASN A CB    1 
ATOM   1249 C CG    . ASN C 3 98  ? -82.348  52.109 85.667 1.00 16.26  ? 98  ASN A CG    1 
ATOM   1250 O OD1   . ASN C 3 98  ? -81.671  51.542 84.808 1.00 40.21  ? 98  ASN A OD1   1 
ATOM   1251 N ND2   . ASN C 3 98  ? -83.654  51.918 85.785 1.00 32.23  ? 98  ASN A ND2   1 
ATOM   1252 N N     . SER C 3 99  ? -79.507  54.262 88.629 1.00 15.27  ? 99  SER A N     1 
ATOM   1253 C CA    . SER C 3 99  ? -78.982  55.394 89.386 1.00 16.09  ? 99  SER A CA    1 
ATOM   1254 C C     . SER C 3 99  ? -77.541  55.640 88.966 1.00 23.36  ? 99  SER A C     1 
ATOM   1255 O O     . SER C 3 99  ? -77.105  56.789 88.843 1.00 35.76  ? 99  SER A O     1 
ATOM   1256 C CB    . SER C 3 99  ? -79.040  55.117 90.891 1.00 8.59   ? 99  SER A CB    1 
ATOM   1257 O OG    . SER C 3 99  ? -78.672  53.781 91.195 1.00 44.17  ? 99  SER A OG    1 
ATOM   1258 N N     . ASP C 3 100 ? -76.806  54.550 88.753 1.00 21.63  ? 100 ASP A N     1 
ATOM   1259 C CA    . ASP C 3 100 ? -75.415  54.636 88.332 1.00 10.50  ? 100 ASP A CA    1 
ATOM   1260 C C     . ASP C 3 100 ? -75.371  55.432 87.025 1.00 24.45  ? 100 ASP A C     1 
ATOM   1261 O O     . ASP C 3 100 ? -74.524  56.310 86.847 1.00 20.63  ? 100 ASP A O     1 
ATOM   1262 C CB    . ASP C 3 100 ? -74.842  53.234 88.095 1.00 13.18  ? 100 ASP A CB    1 
ATOM   1263 C CG    . ASP C 3 100 ? -74.455  52.521 89.384 1.00 20.30  ? 100 ASP A CG    1 
ATOM   1264 O OD1   . ASP C 3 100 ? -74.086  53.191 90.373 1.00 16.68  ? 100 ASP A OD1   1 
ATOM   1265 O OD2   . ASP C 3 100 ? -74.516  51.272 89.400 1.00 25.56  ? 100 ASP A OD2   1 
ATOM   1266 N N     . CYS C 3 101 ? -76.300  55.125 86.118 1.00 18.44  ? 101 CYS A N     1 
ATOM   1267 C CA    . CYS C 3 101 ? -76.360  55.794 84.823 1.00 12.51  ? 101 CYS A CA    1 
ATOM   1268 C C     . CYS C 3 101 ? -76.804  57.247 84.908 1.00 22.94  ? 101 CYS A C     1 
ATOM   1269 O O     . CYS C 3 101 ? -76.335  58.087 84.136 1.00 29.89  ? 101 CYS A O     1 
ATOM   1270 C CB    . CYS C 3 101 ? -77.274  55.021 83.877 1.00 16.83  ? 101 CYS A CB    1 
ATOM   1271 S SG    . CYS C 3 101 ? -76.634  53.380 83.449 1.00 26.38  ? 101 CYS A SG    1 
ATOM   1272 N N     . GLU C 3 102 ? -77.708  57.549 85.834 1.00 15.62  ? 102 GLU A N     1 
ATOM   1273 C CA    . GLU C 3 102 ? -78.164  58.925 85.996 1.00 19.36  ? 102 GLU A CA    1 
ATOM   1274 C C     . GLU C 3 102 ? -76.959  59.769 86.389 1.00 19.74  ? 102 GLU A C     1 
ATOM   1275 O O     . GLU C 3 102 ? -76.853  60.941 86.023 1.00 27.75  ? 102 GLU A O     1 
ATOM   1276 C CB    . GLU C 3 102 ? -79.225  59.015 87.086 1.00 19.54  ? 102 GLU A CB    1 
ATOM   1277 C CG    . GLU C 3 102 ? -80.571  58.441 86.690 1.00 54.12  ? 102 GLU A CG    1 
ATOM   1278 C CD    . GLU C 3 102 ? -81.547  58.408 87.847 1.00 63.28  ? 102 GLU A CD    1 
ATOM   1279 O OE1   . GLU C 3 102 ? -81.421  59.270 88.752 1.00 69.48  ? 102 GLU A OE1   1 
ATOM   1280 O OE2   . GLU C 3 102 ? -82.433  57.520 87.848 1.00 60.95  ? 102 GLU A OE2   1 
ATOM   1281 N N     . LEU C 3 103 ? -76.053  59.153 87.142 1.00 17.14  ? 103 LEU A N     1 
ATOM   1282 C CA    . LEU C 3 103 ? -74.835  59.807 87.590 1.00 14.16  ? 103 LEU A CA    1 
ATOM   1283 C C     . LEU C 3 103 ? -74.027  60.242 86.380 1.00 19.14  ? 103 LEU A C     1 
ATOM   1284 O O     . LEU C 3 103 ? -73.514  61.357 86.328 1.00 29.48  ? 103 LEU A O     1 
ATOM   1285 C CB    . LEU C 3 103 ? -74.011  58.841 88.425 1.00 21.34  ? 103 LEU A CB    1 
ATOM   1286 C CG    . LEU C 3 103 ? -73.508  59.337 89.772 1.00 18.38  ? 103 LEU A CG    1 
ATOM   1287 C CD1   . LEU C 3 103 ? -74.556  60.203 90.439 1.00 24.90  ? 103 LEU A CD1   1 
ATOM   1288 C CD2   . LEU C 3 103 ? -73.181  58.132 90.626 1.00 23.28  ? 103 LEU A CD2   1 
ATOM   1289 N N     . ILE C 3 104 ? -73.921  59.347 85.405 1.00 20.86  ? 104 ILE A N     1 
ATOM   1290 C CA    . ILE C 3 104 ? -73.190  59.626 84.181 1.00 14.48  ? 104 ILE A CA    1 
ATOM   1291 C C     . ILE C 3 104 ? -73.830  60.789 83.427 1.00 20.58  ? 104 ILE A C     1 
ATOM   1292 O O     . ILE C 3 104 ? -73.134  61.691 82.960 1.00 28.54  ? 104 ILE A O     1 
ATOM   1293 C CB    . ILE C 3 104 ? -73.168  58.393 83.272 1.00 14.90  ? 104 ILE A CB    1 
ATOM   1294 C CG1   . ILE C 3 104 ? -72.454  57.241 83.981 1.00 13.83  ? 104 ILE A CG1   1 
ATOM   1295 C CG2   . ILE C 3 104 ? -72.477  58.725 81.969 1.00 9.65   ? 104 ILE A CG2   1 
ATOM   1296 C CD1   . ILE C 3 104 ? -72.549  55.926 83.245 1.00 10.69  ? 104 ILE A CD1   1 
ATOM   1297 N N     . VAL C 3 105 ? -75.155  60.773 83.308 1.00 14.97  ? 105 VAL A N     1 
ATOM   1298 C CA    . VAL C 3 105 ? -75.853  61.845 82.606 1.00 11.37  ? 105 VAL A CA    1 
ATOM   1299 C C     . VAL C 3 105 ? -75.642  63.186 83.305 1.00 18.54  ? 105 VAL A C     1 
ATOM   1300 O O     . VAL C 3 105 ? -75.414  64.209 82.657 1.00 18.68  ? 105 VAL A O     1 
ATOM   1301 C CB    . VAL C 3 105 ? -77.366  61.564 82.496 1.00 12.95  ? 105 VAL A CB    1 
ATOM   1302 C CG1   . VAL C 3 105 ? -78.058  62.732 81.824 1.00 5.74   ? 105 VAL A CG1   1 
ATOM   1303 C CG2   . VAL C 3 105 ? -77.602  60.302 81.684 1.00 14.08  ? 105 VAL A CG2   1 
ATOM   1304 N N     . LYS C 3 106 ? -75.709  63.184 84.631 1.00 16.92  ? 106 LYS A N     1 
ATOM   1305 C CA    . LYS C 3 106 ? -75.501  64.415 85.378 1.00 10.73  ? 106 LYS A CA    1 
ATOM   1306 C C     . LYS C 3 106 ? -74.073  64.927 85.155 1.00 18.89  ? 106 LYS A C     1 
ATOM   1307 O O     . LYS C 3 106 ? -73.857  66.127 84.997 1.00 18.47  ? 106 LYS A O     1 
ATOM   1308 C CB    . LYS C 3 106 ? -75.744  64.178 86.866 1.00 14.00  ? 106 LYS A CB    1 
ATOM   1309 C CG    . LYS C 3 106 ? -77.208  64.050 87.247 1.00 14.78  ? 106 LYS A CG    1 
ATOM   1310 C CD    . LYS C 3 106 ? -77.398  64.288 88.735 1.00 31.04  ? 106 LYS A CD    1 
ATOM   1311 C CE    . LYS C 3 106 ? -78.704  63.705 89.227 1.00 46.11  ? 106 LYS A CE    1 
ATOM   1312 N NZ    . LYS C 3 106 ? -79.864  64.453 88.665 1.00 72.58  ? 106 LYS A NZ    1 
ATOM   1313 N N     . ALA C 3 107 ? -73.098  64.022 85.135 1.00 12.36  ? 107 ALA A N     1 
ATOM   1314 C CA    . ALA C 3 107 ? -71.707  64.429 84.928 1.00 17.52  ? 107 ALA A CA    1 
ATOM   1315 C C     . ALA C 3 107 ? -71.526  65.073 83.558 1.00 17.65  ? 107 ALA A C     1 
ATOM   1316 O O     . ALA C 3 107 ? -70.876  66.115 83.435 1.00 18.20  ? 107 ALA A O     1 
ATOM   1317 C CB    . ALA C 3 107 ? -70.771  63.230 85.067 1.00 7.67   ? 107 ALA A CB    1 
ATOM   1318 N N     . MET C 3 108 ? -72.097  64.455 82.527 1.00 11.20  ? 108 MET A N     1 
ATOM   1319 C CA    . MET C 3 108 ? -71.980  64.997 81.178 1.00 14.30  ? 108 MET A CA    1 
ATOM   1320 C C     . MET C 3 108 ? -72.632  66.362 81.111 1.00 18.00  ? 108 MET A C     1 
ATOM   1321 O O     . MET C 3 108 ? -72.147  67.266 80.429 1.00 21.09  ? 108 MET A O     1 
ATOM   1322 C CB    . MET C 3 108 ? -72.638  64.064 80.173 1.00 14.55  ? 108 MET A CB    1 
ATOM   1323 C CG    . MET C 3 108 ? -71.857  62.786 79.967 1.00 20.94  ? 108 MET A CG    1 
ATOM   1324 S SD    . MET C 3 108 ? -72.531  61.822 78.628 1.00 31.30  ? 108 MET A SD    1 
ATOM   1325 C CE    . MET C 3 108 ? -74.170  61.582 79.196 1.00 34.22  ? 108 MET A CE    1 
ATOM   1326 N N     . GLN C 3 109 ? -73.737  66.508 81.831 1.00 13.88  ? 109 GLN A N     1 
ATOM   1327 C CA    . GLN C 3 109 ? -74.451  67.776 81.863 1.00 15.29  ? 109 GLN A CA    1 
ATOM   1328 C C     . GLN C 3 109 ? -73.603  68.817 82.591 1.00 19.20  ? 109 GLN A C     1 
ATOM   1329 O O     . GLN C 3 109 ? -73.496  69.967 82.156 1.00 22.44  ? 109 GLN A O     1 
ATOM   1330 C CB    . GLN C 3 109 ? -75.794  67.600 82.569 1.00 10.93  ? 109 GLN A CB    1 
ATOM   1331 C CG    . GLN C 3 109 ? -76.811  66.815 81.765 1.00 7.03   ? 109 GLN A CG    1 
ATOM   1332 C CD    . GLN C 3 109 ? -78.038  66.478 82.574 1.00 26.67  ? 109 GLN A CD    1 
ATOM   1333 O OE1   . GLN C 3 109 ? -78.023  66.543 83.808 1.00 35.69  ? 109 GLN A OE1   1 
ATOM   1334 N NE2   . GLN C 3 109 ? -79.115  66.117 81.886 1.00 27.44  ? 109 GLN A NE2   1 
ATOM   1335 N N     . GLY C 3 110 ? -72.994  68.406 83.699 1.00 17.82  ? 110 GLY A N     1 
ATOM   1336 C CA    . GLY C 3 110 ? -72.161  69.319 84.454 1.00 11.26  ? 110 GLY A CA    1 
ATOM   1337 C C     . GLY C 3 110 ? -70.957  69.736 83.635 1.00 17.93  ? 110 GLY A C     1 
ATOM   1338 O O     . GLY C 3 110 ? -70.587  70.905 83.606 1.00 18.15  ? 110 GLY A O     1 
ATOM   1339 N N     . LEU C 3 111 ? -70.346  68.770 82.962 1.00 25.08  ? 111 LEU A N     1 
ATOM   1340 C CA    . LEU C 3 111 ? -69.181  69.035 82.133 1.00 25.89  ? 111 LEU A CA    1 
ATOM   1341 C C     . LEU C 3 111 ? -69.379  70.232 81.204 1.00 24.79  ? 111 LEU A C     1 
ATOM   1342 O O     . LEU C 3 111 ? -68.475  71.047 81.049 1.00 29.09  ? 111 LEU A O     1 
ATOM   1343 C CB    . LEU C 3 111 ? -68.855  67.800 81.297 1.00 24.42  ? 111 LEU A CB    1 
ATOM   1344 C CG    . LEU C 3 111 ? -67.610  67.888 80.422 1.00 15.84  ? 111 LEU A CG    1 
ATOM   1345 C CD1   . LEU C 3 111 ? -66.380  67.701 81.278 1.00 27.44  ? 111 LEU A CD1   1 
ATOM   1346 C CD2   . LEU C 3 111 ? -67.667  66.824 79.356 1.00 16.72  ? 111 LEU A CD2   1 
ATOM   1347 N N     . LEU C 3 112 ? -70.566  70.348 80.606 1.00 16.57  ? 112 LEU A N     1 
ATOM   1348 C CA    . LEU C 3 112 ? -70.846  71.428 79.655 1.00 22.83  ? 112 LEU A CA    1 
ATOM   1349 C C     . LEU C 3 112 ? -71.665  72.620 80.126 1.00 22.94  ? 112 LEU A C     1 
ATOM   1350 O O     . LEU C 3 112 ? -72.035  73.471 79.316 1.00 24.78  ? 112 LEU A O     1 
ATOM   1351 C CB    . LEU C 3 112 ? -71.526  70.852 78.416 1.00 11.44  ? 112 LEU A CB    1 
ATOM   1352 C CG    . LEU C 3 112 ? -70.820  69.638 77.829 1.00 22.03  ? 112 LEU A CG    1 
ATOM   1353 C CD1   . LEU C 3 112 ? -71.841  68.714 77.215 1.00 15.60  ? 112 LEU A CD1   1 
ATOM   1354 C CD2   . LEU C 3 112 ? -69.819  70.091 76.795 1.00 13.79  ? 112 LEU A CD2   1 
ATOM   1355 N N     . LYS C 3 113 ? -71.959  72.696 81.417 1.00 20.77  ? 113 LYS A N     1 
ATOM   1356 C CA    . LYS C 3 113 ? -72.747  73.818 81.918 1.00 21.34  ? 113 LYS A CA    1 
ATOM   1357 C C     . LYS C 3 113 ? -72.072  75.161 81.625 1.00 24.91  ? 113 LYS A C     1 
ATOM   1358 O O     . LYS C 3 113 ? -70.843  75.282 81.724 1.00 22.05  ? 113 LYS A O     1 
ATOM   1359 C CB    . LYS C 3 113 ? -72.972  73.677 83.427 1.00 12.77  ? 113 LYS A CB    1 
ATOM   1360 C CG    . LYS C 3 113 ? -74.164  74.468 83.948 1.00 26.80  ? 113 LYS A CG    1 
ATOM   1361 C CD    . LYS C 3 113 ? -74.027  74.812 85.427 1.00 42.74  ? 113 LYS A CD    1 
ATOM   1362 C CE    . LYS C 3 113 ? -75.387  74.840 86.122 1.00 50.99  ? 113 LYS A CE    1 
ATOM   1363 N NZ    . LYS C 3 113 ? -75.328  75.517 87.451 1.00 66.02  ? 113 LYS A NZ    1 
ATOM   1364 N N     . ASP C 3 114 ? -72.868  76.166 81.258 1.00 17.96  ? 114 ASP A N     1 
ATOM   1365 C CA    . ASP C 3 114 ? -72.313  77.496 80.984 1.00 23.44  ? 114 ASP A CA    1 
ATOM   1366 C C     . ASP C 3 114 ? -71.471  77.928 82.179 1.00 14.34  ? 114 ASP A C     1 
ATOM   1367 O O     . ASP C 3 114 ? -71.871  77.761 83.335 1.00 24.84  ? 114 ASP A O     1 
ATOM   1368 C CB    . ASP C 3 114 ? -73.417  78.543 80.775 1.00 15.39  ? 114 ASP A CB    1 
ATOM   1369 C CG    . ASP C 3 114 ? -73.987  78.523 79.380 1.00 44.78  ? 114 ASP A CG    1 
ATOM   1370 O OD1   . ASP C 3 114 ? -73.255  78.141 78.441 1.00 60.54  ? 114 ASP A OD1   1 
ATOM   1371 O OD2   . ASP C 3 114 ? -75.173  78.890 79.223 1.00 64.29  ? 114 ASP A OD2   1 
ATOM   1372 N N     . GLY C 3 115 ? -70.303  78.482 81.899 1.00 12.88  ? 115 GLY A N     1 
ATOM   1373 C CA    . GLY C 3 115 ? -69.448  78.939 82.971 1.00 13.47  ? 115 GLY A CA    1 
ATOM   1374 C C     . GLY C 3 115 ? -68.302  78.010 83.287 1.00 23.31  ? 115 GLY A C     1 
ATOM   1375 O O     . GLY C 3 115 ? -67.224  78.465 83.664 1.00 40.87  ? 115 GLY A O     1 
ATOM   1376 N N     . ASN C 3 116 ? -68.516  76.710 83.134 1.00 24.70  ? 116 ASN A N     1 
ATOM   1377 C CA    . ASN C 3 116 ? -67.457  75.766 83.436 1.00 19.89  ? 116 ASN A CA    1 
ATOM   1378 C C     . ASN C 3 116 ? -66.293  75.849 82.457 1.00 23.63  ? 116 ASN A C     1 
ATOM   1379 O O     . ASN C 3 116 ? -66.437  76.329 81.332 1.00 22.06  ? 116 ASN A O     1 
ATOM   1380 C CB    . ASN C 3 116 ? -68.039  74.365 83.532 1.00 23.03  ? 116 ASN A CB    1 
ATOM   1381 C CG    . ASN C 3 116 ? -68.929  74.211 84.750 1.00 28.84  ? 116 ASN A CG    1 
ATOM   1382 O OD1   . ASN C 3 116 ? -68.980  75.105 85.595 1.00 22.73  ? 116 ASN A OD1   1 
ATOM   1383 N ND2   . ASN C 3 116 ? -69.631  73.088 84.851 1.00 29.98  ? 116 ASN A ND2   1 
ATOM   1384 N N     . PRO C 3 117 ? -65.116  75.375 82.879 1.00 22.52  ? 117 PRO A N     1 
ATOM   1385 C CA    . PRO C 3 117 ? -63.901  75.400 82.063 1.00 21.97  ? 117 PRO A CA    1 
ATOM   1386 C C     . PRO C 3 117 ? -63.997  74.954 80.605 1.00 31.44  ? 117 PRO A C     1 
ATOM   1387 O O     . PRO C 3 117 ? -63.763  75.752 79.692 1.00 28.12  ? 117 PRO A O     1 
ATOM   1388 C CB    . PRO C 3 117 ? -62.918  74.545 82.863 1.00 25.79  ? 117 PRO A CB    1 
ATOM   1389 C CG    . PRO C 3 117 ? -63.385  74.666 84.264 1.00 21.23  ? 117 PRO A CG    1 
ATOM   1390 C CD    . PRO C 3 117 ? -64.884  74.728 84.183 1.00 16.99  ? 117 PRO A CD    1 
ATOM   1391 N N     . ILE C 3 118 ? -64.330  73.687 80.376 1.00 21.51  ? 118 ILE A N     1 
ATOM   1392 C CA    . ILE C 3 118 ? -64.397  73.191 79.014 1.00 17.93  ? 118 ILE A CA    1 
ATOM   1393 C C     . ILE C 3 118 ? -65.275  74.026 78.069 1.00 23.31  ? 118 ILE A C     1 
ATOM   1394 O O     . ILE C 3 118 ? -64.787  74.523 77.050 1.00 26.98  ? 118 ILE A O     1 
ATOM   1395 C CB    . ILE C 3 118 ? -64.814  71.706 78.999 1.00 12.36  ? 118 ILE A CB    1 
ATOM   1396 C CG1   . ILE C 3 118 ? -63.594  70.848 79.336 1.00 11.56  ? 118 ILE A CG1   1 
ATOM   1397 C CG2   . ILE C 3 118 ? -65.333  71.303 77.617 1.00 14.79  ? 118 ILE A CG2   1 
ATOM   1398 C CD1   . ILE C 3 118 ? -63.684  70.141 80.649 1.00 22.45  ? 118 ILE A CD1   1 
ATOM   1399 N N     . PRO C 3 119 ? -66.567  74.211 78.390 1.00 16.67  ? 119 PRO A N     1 
ATOM   1400 C CA    . PRO C 3 119 ? -67.366  75.017 77.454 1.00 14.94  ? 119 PRO A CA    1 
ATOM   1401 C C     . PRO C 3 119 ? -66.814  76.430 77.257 1.00 19.88  ? 119 PRO A C     1 
ATOM   1402 O O     . PRO C 3 119 ? -66.941  77.017 76.185 1.00 28.03  ? 119 PRO A O     1 
ATOM   1403 C CB    . PRO C 3 119 ? -68.772  75.018 78.061 1.00 2.83   ? 119 PRO A CB    1 
ATOM   1404 C CG    . PRO C 3 119 ? -68.608  74.551 79.473 1.00 12.04  ? 119 PRO A CG    1 
ATOM   1405 C CD    . PRO C 3 119 ? -67.354  73.726 79.538 1.00 15.40  ? 119 PRO A CD    1 
ATOM   1406 N N     . SER C 3 120 ? -66.185  76.971 78.292 1.00 25.33  ? 120 SER A N     1 
ATOM   1407 C CA    . SER C 3 120 ? -65.613  78.310 78.210 1.00 20.06  ? 120 SER A CA    1 
ATOM   1408 C C     . SER C 3 120 ? -64.501  78.372 77.180 1.00 21.03  ? 120 SER A C     1 
ATOM   1409 O O     . SER C 3 120 ? -64.491  79.253 76.320 1.00 30.16  ? 120 SER A O     1 
ATOM   1410 C CB    . SER C 3 120 ? -65.060  78.730 79.566 1.00 12.98  ? 120 SER A CB    1 
ATOM   1411 O OG    . SER C 3 120 ? -66.116  78.901 80.495 1.00 29.14  ? 120 SER A OG    1 
ATOM   1412 N N     . ALA C 3 121 ? -63.566  77.432 77.277 1.00 20.72  ? 121 ALA A N     1 
ATOM   1413 C CA    . ALA C 3 121 ? -62.437  77.366 76.358 1.00 20.86  ? 121 ALA A CA    1 
ATOM   1414 C C     . ALA C 3 121 ? -62.907  77.204 74.918 1.00 17.46  ? 121 ALA A C     1 
ATOM   1415 O O     . ALA C 3 121 ? -62.464  77.923 74.026 1.00 24.45  ? 121 ALA A O     1 
ATOM   1416 C CB    . ALA C 3 121 ? -61.526  76.209 76.737 1.00 13.40  ? 121 ALA A CB    1 
ATOM   1417 N N     . ILE C 3 122 ? -63.808  76.256 74.698 1.00 18.56  ? 122 ILE A N     1 
ATOM   1418 C CA    . ILE C 3 122 ? -64.328  75.987 73.366 1.00 18.20  ? 122 ILE A CA    1 
ATOM   1419 C C     . ILE C 3 122 ? -64.933  77.236 72.735 1.00 24.16  ? 122 ILE A C     1 
ATOM   1420 O O     . ILE C 3 122 ? -64.632  77.586 71.593 1.00 20.00  ? 122 ILE A O     1 
ATOM   1421 C CB    . ILE C 3 122 ? -65.403  74.876 73.419 1.00 19.32  ? 122 ILE A CB    1 
ATOM   1422 C CG1   . ILE C 3 122 ? -64.742  73.550 73.793 1.00 14.82  ? 122 ILE A CG1   1 
ATOM   1423 C CG2   . ILE C 3 122 ? -66.106  74.743 72.073 1.00 5.94   ? 122 ILE A CG2   1 
ATOM   1424 C CD1   . ILE C 3 122 ? -65.726  72.448 74.093 1.00 9.60   ? 122 ILE A CD1   1 
ATOM   1425 N N     . ALA C 3 123 ? -65.781  77.915 73.492 1.00 18.05  ? 123 ALA A N     1 
ATOM   1426 C CA    . ALA C 3 123 ? -66.446  79.107 72.990 1.00 22.53  ? 123 ALA A CA    1 
ATOM   1427 C C     . ALA C 3 123 ? -65.511  80.280 72.764 1.00 18.41  ? 123 ALA A C     1 
ATOM   1428 O O     . ALA C 3 123 ? -65.887  81.267 72.131 1.00 31.63  ? 123 ALA A O     1 
ATOM   1429 C CB    . ALA C 3 123 ? -67.548  79.513 73.941 1.00 5.80   ? 123 ALA A CB    1 
ATOM   1430 N N     . ALA C 3 124 ? -64.298  80.185 73.286 1.00 18.48  ? 124 ALA A N     1 
ATOM   1431 C CA    . ALA C 3 124 ? -63.346  81.274 73.134 1.00 17.48  ? 124 ALA A CA    1 
ATOM   1432 C C     . ALA C 3 124 ? -62.194  80.897 72.231 1.00 22.00  ? 124 ALA A C     1 
ATOM   1433 O O     . ALA C 3 124 ? -61.200  81.606 72.168 1.00 27.82  ? 124 ALA A O     1 
ATOM   1434 C CB    . ALA C 3 124 ? -62.815  81.683 74.483 1.00 7.00   ? 124 ALA A CB    1 
ATOM   1435 N N     . ASN C 3 125 ? -62.318  79.775 71.538 1.00 22.87  ? 125 ASN A N     1 
ATOM   1436 C CA    . ASN C 3 125 ? -61.254  79.358 70.649 1.00 24.29  ? 125 ASN A CA    1 
ATOM   1437 C C     . ASN C 3 125 ? -59.944  79.339 71.415 1.00 28.40  ? 125 ASN A C     1 
ATOM   1438 O O     . ASN C 3 125 ? -58.953  79.902 70.962 1.00 40.38  ? 125 ASN A O     1 
ATOM   1439 C CB    . ASN C 3 125 ? -61.142  80.343 69.488 1.00 25.04  ? 125 ASN A CB    1 
ATOM   1440 C CG    . ASN C 3 125 ? -61.972  79.930 68.301 1.00 24.95  ? 125 ASN A CG    1 
ATOM   1441 O OD1   . ASN C 3 125 ? -61.674  78.936 67.647 1.00 25.34  ? 125 ASN A OD1   1 
ATOM   1442 N ND2   . ASN C 3 125 ? -63.022  80.688 68.016 1.00 28.41  ? 125 ASN A ND2   1 
ATOM   1443 N N     . SER C 3 126 ? -59.932  78.703 72.580 1.00 31.57  ? 126 SER A N     1 
ATOM   1444 C CA    . SER C 3 126 ? -58.713  78.645 73.375 1.00 25.78  ? 126 SER A CA    1 
ATOM   1445 C C     . SER C 3 126 ? -58.595  77.320 74.093 1.00 26.30  ? 126 SER A C     1 
ATOM   1446 O O     . SER C 3 126 ? -59.528  76.518 74.082 1.00 21.66  ? 126 SER A O     1 
ATOM   1447 C CB    . SER C 3 126 ? -58.707  79.769 74.405 1.00 29.62  ? 126 SER A CB    1 
ATOM   1448 O OG    . SER C 3 126 ? -59.139  79.299 75.665 1.00 20.97  ? 126 SER A OG    1 
ATOM   1449 N N     . GLY C 3 127 ? -57.445  77.090 74.716 1.00 19.35  ? 127 GLY A N     1 
ATOM   1450 C CA    . GLY C 3 127 ? -57.259  75.858 75.456 1.00 15.62  ? 127 GLY A CA    1 
ATOM   1451 C C     . GLY C 3 127 ? -57.512  76.111 76.934 1.00 24.64  ? 127 GLY A C     1 
ATOM   1452 O O     . GLY C 3 127 ? -58.086  77.136 77.309 1.00 17.57  ? 127 GLY A O     1 
ATOM   1453 N N     . ILE C 3 128 ? -57.099  75.176 77.779 1.00 29.14  ? 128 ILE A N     1 
ATOM   1454 C CA    . ILE C 3 128 ? -57.267  75.341 79.215 1.00 25.06  ? 128 ILE A CA    1 
ATOM   1455 C C     . ILE C 3 128 ? -55.932  75.827 79.777 1.00 25.45  ? 128 ILE A C     1 
ATOM   1456 O O     . ILE C 3 128 ? -54.870  75.355 79.369 1.00 30.42  ? 128 ILE A O     1 
ATOM   1457 C CB    . ILE C 3 128 ? -57.688  74.009 79.882 1.00 19.65  ? 128 ILE A CB    1 
ATOM   1458 C CG1   . ILE C 3 128 ? -59.207  73.938 79.942 1.00 18.64  ? 128 ILE A CG1   1 
ATOM   1459 C CG2   . ILE C 3 128 ? -57.149  73.912 81.290 1.00 24.89  ? 128 ILE A CG2   1 
ATOM   1460 C CD1   . ILE C 3 128 ? -59.807  73.391 78.702 1.00 26.92  ? 128 ILE A CD1   1 
ATOM   1461 N N     . TYR C 3 129 ? -55.985  76.780 80.700 1.00 20.50  ? 129 TYR A N     1 
ATOM   1462 C CA    . TYR C 3 129 ? -54.769  77.319 81.291 1.00 23.17  ? 129 TYR A CA    1 
ATOM   1463 C C     . TYR C 3 129 ? -55.065  78.091 82.578 1.00 32.92  ? 129 TYR A C     1 
ATOM   1464 O O     . TYR C 3 129 ? -54.112  78.349 83.348 1.00 42.14  ? 129 TYR A O     1 
ATOM   1465 C CB    . TYR C 3 129 ? -54.068  78.231 80.279 1.00 18.82  ? 129 TYR A CB    1 
ATOM   1466 C CG    . TYR C 3 129 ? -54.905  79.411 79.834 1.00 23.06  ? 129 TYR A CG    1 
ATOM   1467 C CD1   . TYR C 3 129 ? -55.834  79.279 78.806 1.00 25.44  ? 129 TYR A CD1   1 
ATOM   1468 C CD2   . TYR C 3 129 ? -54.775  80.658 80.447 1.00 22.83  ? 129 TYR A CD2   1 
ATOM   1469 C CE1   . TYR C 3 129 ? -56.617  80.357 78.397 1.00 28.57  ? 129 TYR A CE1   1 
ATOM   1470 C CE2   . TYR C 3 129 ? -55.554  81.746 80.044 1.00 21.27  ? 129 TYR A CE2   1 
ATOM   1471 C CZ    . TYR C 3 129 ? -56.472  81.586 79.021 1.00 27.97  ? 129 TYR A CZ    1 
ATOM   1472 O OH    . TYR C 3 129 ? -57.259  82.645 78.626 1.00 45.64  ? 129 TYR A OH    1 
ATOM   1473 O OXT   . TYR C 3 129 ? -56.246  78.425 82.804 1.00 26.78  ? 129 TYR A OXT   1 
ATOM   1474 N N     . ALA D 3 1   ? -103.420 48.806 65.722 1.00 98.16  ? 1   ALA B N     1 
ATOM   1475 C CA    . ALA D 3 1   ? -102.731 48.206 66.898 1.00 90.99  ? 1   ALA B CA    1 
ATOM   1476 C C     . ALA D 3 1   ? -101.477 48.987 67.284 1.00 85.65  ? 1   ALA B C     1 
ATOM   1477 O O     . ALA D 3 1   ? -101.435 50.221 67.194 1.00 82.38  ? 1   ALA B O     1 
ATOM   1478 C CB    . ALA D 3 1   ? -102.366 46.737 66.610 1.00 71.95  ? 1   ALA B CB    1 
ATOM   1479 N N     . SER D 3 2   ? -100.469 48.230 67.703 1.00 65.95  ? 2   SER B N     1 
ATOM   1480 C CA    . SER D 3 2   ? -99.168  48.714 68.158 1.00 54.67  ? 2   SER B CA    1 
ATOM   1481 C C     . SER D 3 2   ? -98.964  47.936 69.442 1.00 47.41  ? 2   SER B C     1 
ATOM   1482 O O     . SER D 3 2   ? -99.287  48.409 70.527 1.00 58.21  ? 2   SER B O     1 
ATOM   1483 C CB    . SER D 3 2   ? -99.167  50.211 68.471 1.00 44.87  ? 2   SER B CB    1 
ATOM   1484 O OG    . SER D 3 2   ? -97.920  50.598 69.034 1.00 50.99  ? 2   SER B OG    1 
ATOM   1485 N N     . ASN D 3 3   ? -98.442  46.728 69.296 1.00 35.03  ? 3   ASN B N     1 
ATOM   1486 C CA    . ASN D 3 3   ? -98.212  45.833 70.410 1.00 28.87  ? 3   ASN B CA    1 
ATOM   1487 C C     . ASN D 3 3   ? -96.938  46.086 71.217 1.00 28.71  ? 3   ASN B C     1 
ATOM   1488 O O     . ASN D 3 3   ? -96.751  45.481 72.271 1.00 40.27  ? 3   ASN B O     1 
ATOM   1489 C CB    . ASN D 3 3   ? -98.202  44.397 69.891 1.00 32.66  ? 3   ASN B CB    1 
ATOM   1490 C CG    . ASN D 3 3   ? -97.593  44.283 68.498 1.00 38.39  ? 3   ASN B CG    1 
ATOM   1491 O OD1   . ASN D 3 3   ? -98.145  43.618 67.621 1.00 44.95  ? 3   ASN B OD1   1 
ATOM   1492 N ND2   . ASN D 3 3   ? -96.451  44.933 68.293 1.00 32.87  ? 3   ASN B ND2   1 
ATOM   1493 N N     . PHE D 3 4   ? -96.061  46.963 70.741 1.00 21.83  ? 4   PHE B N     1 
ATOM   1494 C CA    . PHE D 3 4   ? -94.819  47.215 71.463 1.00 19.56  ? 4   PHE B CA    1 
ATOM   1495 C C     . PHE D 3 4   ? -95.030  48.054 72.714 1.00 22.23  ? 4   PHE B C     1 
ATOM   1496 O O     . PHE D 3 4   ? -94.649  49.228 72.771 1.00 24.79  ? 4   PHE B O     1 
ATOM   1497 C CB    . PHE D 3 4   ? -93.780  47.884 70.553 1.00 11.32  ? 4   PHE B CB    1 
ATOM   1498 C CG    . PHE D 3 4   ? -92.364  47.763 71.058 1.00 14.23  ? 4   PHE B CG    1 
ATOM   1499 C CD1   . PHE D 3 4   ? -92.034  46.828 72.036 1.00 22.59  ? 4   PHE B CD1   1 
ATOM   1500 C CD2   . PHE D 3 4   ? -91.358  48.576 70.552 1.00 15.00  ? 4   PHE B CD2   1 
ATOM   1501 C CE1   . PHE D 3 4   ? -90.726  46.707 72.498 1.00 25.34  ? 4   PHE B CE1   1 
ATOM   1502 C CE2   . PHE D 3 4   ? -90.043  48.461 71.008 1.00 14.48  ? 4   PHE B CE2   1 
ATOM   1503 C CZ    . PHE D 3 4   ? -89.727  47.527 71.980 1.00 25.46  ? 4   PHE B CZ    1 
ATOM   1504 N N     . THR D 3 5   ? -95.626  47.428 73.722 1.00 18.98  ? 5   THR B N     1 
ATOM   1505 C CA    . THR D 3 5   ? -95.906  48.088 74.987 1.00 27.83  ? 5   THR B CA    1 
ATOM   1506 C C     . THR D 3 5   ? -95.378  47.277 76.155 1.00 26.69  ? 5   THR B C     1 
ATOM   1507 O O     . THR D 3 5   ? -95.028  46.106 76.007 1.00 27.65  ? 5   THR B O     1 
ATOM   1508 C CB    . THR D 3 5   ? -97.403  48.267 75.192 1.00 18.59  ? 5   THR B CB    1 
ATOM   1509 O OG1   . THR D 3 5   ? -98.012  46.978 75.308 1.00 27.33  ? 5   THR B OG1   1 
ATOM   1510 C CG2   . THR D 3 5   ? -98.012  49.011 74.015 1.00 38.35  ? 5   THR B CG2   1 
ATOM   1511 N N     . GLN D 3 6   ? -95.330  47.903 77.324 1.00 24.46  ? 6   GLN B N     1 
ATOM   1512 C CA    . GLN D 3 6   ? -94.842  47.213 78.499 1.00 20.86  ? 6   GLN B CA    1 
ATOM   1513 C C     . GLN D 3 6   ? -95.853  46.171 78.940 1.00 18.73  ? 6   GLN B C     1 
ATOM   1514 O O     . GLN D 3 6   ? -97.034  46.267 78.620 1.00 27.39  ? 6   GLN B O     1 
ATOM   1515 C CB    . GLN D 3 6   ? -94.582  48.210 79.623 1.00 29.55  ? 6   GLN B CB    1 
ATOM   1516 C CG    . GLN D 3 6   ? -95.755  48.452 80.539 1.00 33.53  ? 6   GLN B CG    1 
ATOM   1517 C CD    . GLN D 3 6   ? -95.419  49.423 81.653 1.00 52.24  ? 6   GLN B CD    1 
ATOM   1518 O OE1   . GLN D 3 6   ? -96.266  50.200 82.086 1.00 78.42  ? 6   GLN B OE1   1 
ATOM   1519 N NE2   . GLN D 3 6   ? -94.177  49.385 82.123 1.00 51.61  ? 6   GLN B NE2   1 
ATOM   1520 N N     . PHE D 3 7   ? -95.378  45.159 79.655 1.00 22.73  ? 7   PHE B N     1 
ATOM   1521 C CA    . PHE D 3 7   ? -96.250  44.109 80.147 1.00 10.27  ? 7   PHE B CA    1 
ATOM   1522 C C     . PHE D 3 7   ? -95.659  43.405 81.367 1.00 21.32  ? 7   PHE B C     1 
ATOM   1523 O O     . PHE D 3 7   ? -94.493  43.612 81.719 1.00 23.42  ? 7   PHE B O     1 
ATOM   1524 C CB    . PHE D 3 7   ? -96.574  43.101 79.029 1.00 12.65  ? 7   PHE B CB    1 
ATOM   1525 C CG    . PHE D 3 7   ? -95.400  42.286 78.558 1.00 20.33  ? 7   PHE B CG    1 
ATOM   1526 C CD1   . PHE D 3 7   ? -94.514  42.795 77.611 1.00 16.91  ? 7   PHE B CD1   1 
ATOM   1527 C CD2   . PHE D 3 7   ? -95.212  40.982 79.019 1.00 16.89  ? 7   PHE B CD2   1 
ATOM   1528 C CE1   . PHE D 3 7   ? -93.458  42.015 77.124 1.00 18.57  ? 7   PHE B CE1   1 
ATOM   1529 C CE2   . PHE D 3 7   ? -94.156  40.191 78.536 1.00 14.84  ? 7   PHE B CE2   1 
ATOM   1530 C CZ    . PHE D 3 7   ? -93.281  40.709 77.588 1.00 9.01   ? 7   PHE B CZ    1 
ATOM   1531 N N     . VAL D 3 8   ? -96.487  42.599 82.026 1.00 9.02   ? 8   VAL B N     1 
ATOM   1532 C CA    . VAL D 3 8   ? -96.069  41.871 83.215 1.00 20.49  ? 8   VAL B CA    1 
ATOM   1533 C C     . VAL D 3 8   ? -95.498  40.532 82.804 1.00 18.33  ? 8   VAL B C     1 
ATOM   1534 O O     . VAL D 3 8   ? -96.200  39.688 82.254 1.00 17.27  ? 8   VAL B O     1 
ATOM   1535 C CB    . VAL D 3 8   ? -97.257  41.641 84.174 1.00 14.25  ? 8   VAL B CB    1 
ATOM   1536 C CG1   . VAL D 3 8   ? -96.810  40.876 85.413 1.00 13.81  ? 8   VAL B CG1   1 
ATOM   1537 C CG2   . VAL D 3 8   ? -97.830  42.963 84.578 1.00 5.48   ? 8   VAL B CG2   1 
ATOM   1538 N N     . LEU D 3 9   ? -94.216  40.344 83.077 1.00 13.79  ? 9   LEU B N     1 
ATOM   1539 C CA    . LEU D 3 9   ? -93.549  39.114 82.715 1.00 11.80  ? 9   LEU B CA    1 
ATOM   1540 C C     . LEU D 3 9   ? -93.763  38.084 83.807 1.00 14.71  ? 9   LEU B C     1 
ATOM   1541 O O     . LEU D 3 9   ? -94.119  36.940 83.537 1.00 23.30  ? 9   LEU B O     1 
ATOM   1542 C CB    . LEU D 3 9   ? -92.060  39.391 82.525 1.00 17.27  ? 9   LEU B CB    1 
ATOM   1543 C CG    . LEU D 3 9   ? -91.208  38.212 82.075 1.00 21.75  ? 9   LEU B CG    1 
ATOM   1544 C CD1   . LEU D 3 9   ? -91.653  37.771 80.689 1.00 9.24   ? 9   LEU B CD1   1 
ATOM   1545 C CD2   . LEU D 3 9   ? -89.737  38.628 82.093 1.00 7.70   ? 9   LEU B CD2   1 
ATOM   1546 N N     . VAL D 3 10  ? -93.542  38.501 85.046 1.00 22.18  ? 10  VAL B N     1 
ATOM   1547 C CA    . VAL D 3 10  ? -93.703  37.619 86.191 1.00 20.34  ? 10  VAL B CA    1 
ATOM   1548 C C     . VAL D 3 10  ? -94.855  38.135 87.028 1.00 26.22  ? 10  VAL B C     1 
ATOM   1549 O O     . VAL D 3 10  ? -94.780  39.211 87.621 1.00 21.94  ? 10  VAL B O     1 
ATOM   1550 C CB    . VAL D 3 10  ? -92.436  37.590 87.070 1.00 18.49  ? 10  VAL B CB    1 
ATOM   1551 C CG1   . VAL D 3 10  ? -92.670  36.701 88.281 1.00 7.53   ? 10  VAL B CG1   1 
ATOM   1552 C CG2   . VAL D 3 10  ? -91.257  37.095 86.259 1.00 15.87  ? 10  VAL B CG2   1 
ATOM   1553 N N     . ASP D 3 11  ? -95.926  37.359 87.062 1.00 27.89  ? 11  ASP B N     1 
ATOM   1554 C CA    . ASP D 3 11  ? -97.106  37.718 87.824 1.00 27.04  ? 11  ASP B CA    1 
ATOM   1555 C C     . ASP D 3 11  ? -97.048  37.072 89.198 1.00 32.33  ? 11  ASP B C     1 
ATOM   1556 O O     . ASP D 3 11  ? -97.315  35.878 89.352 1.00 40.14  ? 11  ASP B O     1 
ATOM   1557 C CB    . ASP D 3 11  ? -98.355  37.255 87.085 1.00 35.61  ? 11  ASP B CB    1 
ATOM   1558 C CG    . ASP D 3 11  ? -99.623  37.556 87.843 1.00 34.80  ? 11  ASP B CG    1 
ATOM   1559 O OD1   . ASP D 3 11  ? -99.552  38.293 88.848 1.00 46.12  ? 11  ASP B OD1   1 
ATOM   1560 O OD2   . ASP D 3 11  ? -100.691 37.056 87.428 1.00 48.97  ? 11  ASP B OD2   1 
ATOM   1561 N N     . ASN D 3 12  ? -96.682  37.866 90.194 1.00 38.07  ? 12  ASN B N     1 
ATOM   1562 C CA    . ASN D 3 12  ? -96.589  37.378 91.555 1.00 46.46  ? 12  ASN B CA    1 
ATOM   1563 C C     . ASN D 3 12  ? -97.797  37.828 92.363 1.00 58.25  ? 12  ASN B C     1 
ATOM   1564 O O     . ASN D 3 12  ? -97.741  37.919 93.590 1.00 62.42  ? 12  ASN B O     1 
ATOM   1565 C CB    . ASN D 3 12  ? -95.298  37.871 92.193 1.00 36.08  ? 12  ASN B CB    1 
ATOM   1566 C CG    . ASN D 3 12  ? -94.192  36.859 92.074 1.00 59.55  ? 12  ASN B CG    1 
ATOM   1567 O OD1   . ASN D 3 12  ? -94.451  35.649 92.071 1.00 62.61  ? 12  ASN B OD1   1 
ATOM   1568 N ND2   . ASN D 3 12  ? -92.953  37.335 91.968 1.00 57.34  ? 12  ASN B ND2   1 
ATOM   1569 N N     . GLY D 3 13  ? -98.888  38.104 91.652 1.00 55.29  ? 13  GLY B N     1 
ATOM   1570 C CA    . GLY D 3 13  ? -100.120 38.526 92.289 1.00 53.77  ? 13  GLY B CA    1 
ATOM   1571 C C     . GLY D 3 13  ? -100.137 39.961 92.774 1.00 68.45  ? 13  GLY B C     1 
ATOM   1572 O O     . GLY D 3 13  ? -100.234 40.206 93.976 1.00 86.29  ? 13  GLY B O     1 
ATOM   1573 N N     . GLY D 3 14  ? -100.042 40.909 91.846 1.00 74.10  ? 14  GLY B N     1 
ATOM   1574 C CA    . GLY D 3 14  ? -100.065 42.319 92.206 1.00 78.41  ? 14  GLY B CA    1 
ATOM   1575 C C     . GLY D 3 14  ? -98.892  42.845 93.021 1.00 77.98  ? 14  GLY B C     1 
ATOM   1576 O O     . GLY D 3 14  ? -98.360  43.919 92.735 1.00 80.17  ? 14  GLY B O     1 
ATOM   1577 N N     . THR D 3 15  ? -98.484  42.098 94.039 1.00 74.79  ? 15  THR B N     1 
ATOM   1578 C CA    . THR D 3 15  ? -97.382  42.519 94.886 1.00 81.07  ? 15  THR B CA    1 
ATOM   1579 C C     . THR D 3 15  ? -96.082  41.736 94.612 1.00 81.77  ? 15  THR B C     1 
ATOM   1580 O O     . THR D 3 15  ? -95.960  40.547 94.932 1.00 76.67  ? 15  THR B O     1 
ATOM   1581 C CB    . THR D 3 15  ? -97.807  42.420 96.379 1.00 90.90  ? 15  THR B CB    1 
ATOM   1582 O OG1   . THR D 3 15  ? -96.961  43.257 97.173 1.00 99.54  ? 15  THR B OG1   1 
ATOM   1583 C CG2   . THR D 3 15  ? -97.745  40.977 96.881 1.00 97.04  ? 15  THR B CG2   1 
ATOM   1584 N N     . GLY D 3 16  ? -95.113  42.419 94.003 1.00 74.27  ? 16  GLY B N     1 
ATOM   1585 C CA    . GLY D 3 16  ? -93.844  41.787 93.681 1.00 64.09  ? 16  GLY B CA    1 
ATOM   1586 C C     . GLY D 3 16  ? -93.812  41.355 92.228 1.00 53.25  ? 16  GLY B C     1 
ATOM   1587 O O     . GLY D 3 16  ? -93.084  40.438 91.846 1.00 52.79  ? 16  GLY B O     1 
ATOM   1588 N N     . ASP D 3 17  ? -94.613  42.027 91.413 1.00 39.58  ? 17  ASP B N     1 
ATOM   1589 C CA    . ASP D 3 17  ? -94.703  41.719 89.997 1.00 31.14  ? 17  ASP B CA    1 
ATOM   1590 C C     . ASP D 3 17  ? -93.506  42.253 89.243 1.00 34.79  ? 17  ASP B C     1 
ATOM   1591 O O     . ASP D 3 17  ? -92.932  43.275 89.619 1.00 45.83  ? 17  ASP B O     1 
ATOM   1592 C CB    . ASP D 3 17  ? -95.960  42.346 89.398 1.00 30.89  ? 17  ASP B CB    1 
ATOM   1593 C CG    . ASP D 3 17  ? -97.212  41.592 89.757 1.00 37.53  ? 17  ASP B CG    1 
ATOM   1594 O OD1   . ASP D 3 17  ? -97.099  40.530 90.404 1.00 38.17  ? 17  ASP B OD1   1 
ATOM   1595 O OD2   . ASP D 3 17  ? -98.310  42.063 89.386 1.00 37.21  ? 17  ASP B OD2   1 
ATOM   1596 N N     . VAL D 3 18  ? -93.130  41.557 88.176 1.00 31.15  ? 18  VAL B N     1 
ATOM   1597 C CA    . VAL D 3 18  ? -92.021  42.007 87.356 1.00 18.22  ? 18  VAL B CA    1 
ATOM   1598 C C     . VAL D 3 18  ? -92.594  42.470 86.033 1.00 21.72  ? 18  VAL B C     1 
ATOM   1599 O O     . VAL D 3 18  ? -93.243  41.712 85.306 1.00 22.19  ? 18  VAL B O     1 
ATOM   1600 C CB    . VAL D 3 18  ? -90.989  40.902 87.094 1.00 24.85  ? 18  VAL B CB    1 
ATOM   1601 C CG1   . VAL D 3 18  ? -89.819  41.467 86.295 1.00 10.65  ? 18  VAL B CG1   1 
ATOM   1602 C CG2   . VAL D 3 18  ? -90.487  40.354 88.397 1.00 6.39   ? 18  VAL B CG2   1 
ATOM   1603 N N     . THR D 3 19  ? -92.364  43.740 85.747 1.00 21.28  ? 19  THR B N     1 
ATOM   1604 C CA    . THR D 3 19  ? -92.835  44.349 84.524 1.00 20.81  ? 19  THR B CA    1 
ATOM   1605 C C     . THR D 3 19  ? -91.627  44.644 83.653 1.00 19.74  ? 19  THR B C     1 
ATOM   1606 O O     . THR D 3 19  ? -90.578  45.035 84.156 1.00 35.36  ? 19  THR B O     1 
ATOM   1607 C CB    . THR D 3 19  ? -93.552  45.653 84.837 1.00 18.42  ? 19  THR B CB    1 
ATOM   1608 O OG1   . THR D 3 19  ? -94.911  45.363 85.164 1.00 35.17  ? 19  THR B OG1   1 
ATOM   1609 C CG2   . THR D 3 19  ? -93.506  46.595 83.653 1.00 32.72  ? 19  THR B CG2   1 
ATOM   1610 N N     . VAL D 3 20  ? -91.761  44.433 82.352 1.00 15.25  ? 20  VAL B N     1 
ATOM   1611 C CA    . VAL D 3 20  ? -90.667  44.722 81.440 1.00 16.11  ? 20  VAL B CA    1 
ATOM   1612 C C     . VAL D 3 20  ? -91.228  45.758 80.488 1.00 19.30  ? 20  VAL B C     1 
ATOM   1613 O O     . VAL D 3 20  ? -92.411  45.724 80.152 1.00 16.56  ? 20  VAL B O     1 
ATOM   1614 C CB    . VAL D 3 20  ? -90.205  43.471 80.658 1.00 16.82  ? 20  VAL B CB    1 
ATOM   1615 C CG1   . VAL D 3 20  ? -89.533  42.494 81.608 1.00 7.65   ? 20  VAL B CG1   1 
ATOM   1616 C CG2   . VAL D 3 20  ? -91.385  42.819 79.958 1.00 15.66  ? 20  VAL B CG2   1 
ATOM   1617 N N     . ALA D 3 21  ? -90.390  46.691 80.066 1.00 17.06  ? 21  ALA B N     1 
ATOM   1618 C CA    . ALA D 3 21  ? -90.855  47.734 79.175 1.00 14.05  ? 21  ALA B CA    1 
ATOM   1619 C C     . ALA D 3 21  ? -89.926  47.914 77.998 1.00 12.33  ? 21  ALA B C     1 
ATOM   1620 O O     . ALA D 3 21  ? -88.745  47.574 78.067 1.00 21.46  ? 21  ALA B O     1 
ATOM   1621 C CB    . ALA D 3 21  ? -90.972  49.016 79.932 1.00 5.90   ? 21  ALA B CB    1 
ATOM   1622 N N     . PRO D 3 22  ? -90.459  48.427 76.882 1.00 19.04  ? 22  PRO B N     1 
ATOM   1623 C CA    . PRO D 3 22  ? -89.662  48.657 75.669 1.00 17.48  ? 22  PRO B CA    1 
ATOM   1624 C C     . PRO D 3 22  ? -88.348  49.375 75.979 1.00 14.08  ? 22  PRO B C     1 
ATOM   1625 O O     . PRO D 3 22  ? -88.340  50.392 76.669 1.00 27.87  ? 22  PRO B O     1 
ATOM   1626 C CB    . PRO D 3 22  ? -90.590  49.493 74.789 1.00 13.60  ? 22  PRO B CB    1 
ATOM   1627 C CG    . PRO D 3 22  ? -91.975  49.075 75.216 1.00 15.51  ? 22  PRO B CG    1 
ATOM   1628 C CD    . PRO D 3 22  ? -91.880  48.784 76.696 1.00 3.31   ? 22  PRO B CD    1 
ATOM   1629 N N     . SER D 3 23  ? -87.237  48.839 75.482 1.00 16.78  ? 23  SER B N     1 
ATOM   1630 C CA    . SER D 3 23  ? -85.934  49.443 75.731 1.00 15.02  ? 23  SER B CA    1 
ATOM   1631 C C     . SER D 3 23  ? -85.126  49.603 74.450 1.00 22.48  ? 23  SER B C     1 
ATOM   1632 O O     . SER D 3 23  ? -84.128  50.329 74.415 1.00 31.73  ? 23  SER B O     1 
ATOM   1633 C CB    . SER D 3 23  ? -85.146  48.596 76.734 1.00 15.96  ? 23  SER B CB    1 
ATOM   1634 O OG    . SER D 3 23  ? -85.522  47.230 76.656 1.00 26.74  ? 23  SER B OG    1 
ATOM   1635 N N     . ASN D 3 24  ? -85.552  48.925 73.393 1.00 20.54  ? 24  ASN B N     1 
ATOM   1636 C CA    . ASN D 3 24  ? -84.835  49.027 72.141 1.00 17.66  ? 24  ASN B CA    1 
ATOM   1637 C C     . ASN D 3 24  ? -85.597  48.465 70.963 1.00 19.47  ? 24  ASN B C     1 
ATOM   1638 O O     . ASN D 3 24  ? -86.418  47.563 71.121 1.00 22.99  ? 24  ASN B O     1 
ATOM   1639 C CB    . ASN D 3 24  ? -83.495  48.317 72.258 1.00 15.12  ? 24  ASN B CB    1 
ATOM   1640 C CG    . ASN D 3 24  ? -82.480  48.860 71.295 1.00 17.06  ? 24  ASN B CG    1 
ATOM   1641 O OD1   . ASN D 3 24  ? -82.829  49.523 70.321 1.00 37.38  ? 24  ASN B OD1   1 
ATOM   1642 N ND2   . ASN D 3 24  ? -81.215  48.584 71.554 1.00 12.03  ? 24  ASN B ND2   1 
ATOM   1643 N N     . PHE D 3 25  ? -85.313  49.003 69.780 1.00 21.04  ? 25  PHE B N     1 
ATOM   1644 C CA    . PHE D 3 25  ? -85.967  48.558 68.558 1.00 27.67  ? 25  PHE B CA    1 
ATOM   1645 C C     . PHE D 3 25  ? -85.011  48.532 67.387 1.00 26.58  ? 25  PHE B C     1 
ATOM   1646 O O     . PHE D 3 25  ? -85.437  48.499 66.230 1.00 37.93  ? 25  PHE B O     1 
ATOM   1647 C CB    . PHE D 3 25  ? -87.135  49.468 68.207 1.00 28.51  ? 25  PHE B CB    1 
ATOM   1648 C CG    . PHE D 3 25  ? -88.106  48.849 67.245 1.00 44.92  ? 25  PHE B CG    1 
ATOM   1649 C CD1   . PHE D 3 25  ? -88.789  47.685 67.580 1.00 47.80  ? 25  PHE B CD1   1 
ATOM   1650 C CD2   . PHE D 3 25  ? -88.346  49.433 66.009 1.00 62.22  ? 25  PHE B CD2   1 
ATOM   1651 C CE1   . PHE D 3 25  ? -89.699  47.112 66.701 1.00 35.31  ? 25  PHE B CE1   1 
ATOM   1652 C CE2   . PHE D 3 25  ? -89.257  48.866 65.123 1.00 70.13  ? 25  PHE B CE2   1 
ATOM   1653 C CZ    . PHE D 3 25  ? -89.935  47.702 65.474 1.00 52.93  ? 25  PHE B CZ    1 
ATOM   1654 N N     . ALA D 3 26  ? -83.721  48.552 67.686 1.00 16.59  ? 26  ALA B N     1 
ATOM   1655 C CA    . ALA D 3 26  ? -82.713  48.531 66.641 1.00 26.15  ? 26  ALA B CA    1 
ATOM   1656 C C     . ALA D 3 26  ? -82.815  47.264 65.807 1.00 29.94  ? 26  ALA B C     1 
ATOM   1657 O O     . ALA D 3 26  ? -82.773  46.154 66.332 1.00 33.39  ? 26  ALA B O     1 
ATOM   1658 C CB    . ALA D 3 26  ? -81.334  48.640 67.240 1.00 16.28  ? 26  ALA B CB    1 
ATOM   1659 N N     . ASN D 3 27  ? -82.963  47.456 64.501 1.00 38.98  ? 27  ASN B N     1 
ATOM   1660 C CA    . ASN D 3 27  ? -83.059  46.367 63.540 1.00 34.00  ? 27  ASN B CA    1 
ATOM   1661 C C     . ASN D 3 27  ? -84.336  45.557 63.562 1.00 36.54  ? 27  ASN B C     1 
ATOM   1662 O O     . ASN D 3 27  ? -84.329  44.389 63.184 1.00 41.11  ? 27  ASN B O     1 
ATOM   1663 C CB    . ASN D 3 27  ? -81.878  45.433 63.704 1.00 29.61  ? 27  ASN B CB    1 
ATOM   1664 C CG    . ASN D 3 27  ? -80.652  45.953 63.019 1.00 54.18  ? 27  ASN B CG    1 
ATOM   1665 O OD1   . ASN D 3 27  ? -80.596  46.021 61.780 1.00 46.42  ? 27  ASN B OD1   1 
ATOM   1666 N ND2   . ASN D 3 27  ? -79.654  46.340 63.813 1.00 49.26  ? 27  ASN B ND2   1 
ATOM   1667 N N     . GLY D 3 28  ? -85.433  46.173 63.987 1.00 50.25  ? 28  GLY B N     1 
ATOM   1668 C CA    . GLY D 3 28  ? -86.692  45.457 64.025 1.00 53.26  ? 28  GLY B CA    1 
ATOM   1669 C C     . GLY D 3 28  ? -86.754  44.480 65.180 1.00 51.08  ? 28  GLY B C     1 
ATOM   1670 O O     . GLY D 3 28  ? -87.790  43.858 65.409 1.00 64.54  ? 28  GLY B O     1 
ATOM   1671 N N     . VAL D 3 29  ? -85.643  44.322 65.896 1.00 34.02  ? 29  VAL B N     1 
ATOM   1672 C CA    . VAL D 3 29  ? -85.621  43.437 67.051 1.00 25.07  ? 29  VAL B CA    1 
ATOM   1673 C C     . VAL D 3 29  ? -86.137  44.215 68.262 1.00 26.05  ? 29  VAL B C     1 
ATOM   1674 O O     . VAL D 3 29  ? -85.476  45.123 68.762 1.00 27.31  ? 29  VAL B O     1 
ATOM   1675 C CB    . VAL D 3 29  ? -84.212  42.932 67.358 1.00 16.74  ? 29  VAL B CB    1 
ATOM   1676 C CG1   . VAL D 3 29  ? -84.243  42.013 68.572 1.00 19.46  ? 29  VAL B CG1   1 
ATOM   1677 C CG2   . VAL D 3 29  ? -83.673  42.192 66.173 1.00 21.95  ? 29  VAL B CG2   1 
ATOM   1678 N N     . ALA D 3 30  ? -87.334  43.860 68.713 1.00 19.31  ? 30  ALA B N     1 
ATOM   1679 C CA    . ALA D 3 30  ? -87.955  44.514 69.848 1.00 10.66  ? 30  ALA B CA    1 
ATOM   1680 C C     . ALA D 3 30  ? -87.330  43.999 71.130 1.00 20.84  ? 30  ALA B C     1 
ATOM   1681 O O     . ALA D 3 30  ? -87.050  42.805 71.257 1.00 27.87  ? 30  ALA B O     1 
ATOM   1682 C CB    . ALA D 3 30  ? -89.451  44.236 69.854 1.00 9.94   ? 30  ALA B CB    1 
ATOM   1683 N N     . GLU D 3 31  ? -87.108  44.905 72.076 1.00 21.02  ? 31  GLU B N     1 
ATOM   1684 C CA    . GLU D 3 31  ? -86.532  44.535 73.355 1.00 15.37  ? 31  GLU B CA    1 
ATOM   1685 C C     . GLU D 3 31  ? -87.248  45.187 74.530 1.00 18.60  ? 31  GLU B C     1 
ATOM   1686 O O     . GLU D 3 31  ? -87.634  46.354 74.467 1.00 18.16  ? 31  GLU B O     1 
ATOM   1687 C CB    . GLU D 3 31  ? -85.058  44.922 73.422 1.00 7.50   ? 31  GLU B CB    1 
ATOM   1688 C CG    . GLU D 3 31  ? -84.489  44.726 74.817 1.00 16.89  ? 31  GLU B CG    1 
ATOM   1689 C CD    . GLU D 3 31  ? -83.163  45.412 75.018 1.00 27.67  ? 31  GLU B CD    1 
ATOM   1690 O OE1   . GLU D 3 31  ? -83.151  46.604 75.411 1.00 29.68  ? 31  GLU B OE1   1 
ATOM   1691 O OE2   . GLU D 3 31  ? -82.128  44.749 74.787 1.00 13.65  ? 31  GLU B OE2   1 
ATOM   1692 N N     . TRP D 3 32  ? -87.417  44.411 75.596 1.00 17.61  ? 32  TRP B N     1 
ATOM   1693 C CA    . TRP D 3 32  ? -88.032  44.872 76.835 1.00 14.26  ? 32  TRP B CA    1 
ATOM   1694 C C     . TRP D 3 32  ? -87.076  44.455 77.957 1.00 20.90  ? 32  TRP B C     1 
ATOM   1695 O O     . TRP D 3 32  ? -86.412  43.415 77.863 1.00 17.51  ? 32  TRP B O     1 
ATOM   1696 C CB    . TRP D 3 32  ? -89.355  44.163 77.116 1.00 12.37  ? 32  TRP B CB    1 
ATOM   1697 C CG    . TRP D 3 32  ? -90.490  44.371 76.170 1.00 21.10  ? 32  TRP B CG    1 
ATOM   1698 C CD1   . TRP D 3 32  ? -91.601  45.137 76.390 1.00 22.21  ? 32  TRP B CD1   1 
ATOM   1699 C CD2   . TRP D 3 32  ? -90.732  43.661 74.947 1.00 20.59  ? 32  TRP B CD2   1 
ATOM   1700 N NE1   . TRP D 3 32  ? -92.521  44.938 75.390 1.00 19.14  ? 32  TRP B NE1   1 
ATOM   1701 C CE2   . TRP D 3 32  ? -92.013  44.037 74.492 1.00 15.80  ? 32  TRP B CE2   1 
ATOM   1702 C CE3   . TRP D 3 32  ? -89.992  42.738 74.196 1.00 28.10  ? 32  TRP B CE3   1 
ATOM   1703 C CZ2   . TRP D 3 32  ? -92.573  43.523 73.317 1.00 19.50  ? 32  TRP B CZ2   1 
ATOM   1704 C CZ3   . TRP D 3 32  ? -90.551  42.225 73.024 1.00 24.15  ? 32  TRP B CZ3   1 
ATOM   1705 C CH2   . TRP D 3 32  ? -91.829  42.622 72.600 1.00 18.81  ? 32  TRP B CH2   1 
ATOM   1706 N N     . ILE D 3 33  ? -87.001  45.253 79.015 1.00 11.46  ? 33  ILE B N     1 
ATOM   1707 C CA    . ILE D 3 33  ? -86.170  44.889 80.157 1.00 25.73  ? 33  ILE B CA    1 
ATOM   1708 C C     . ILE D 3 33  ? -86.814  45.414 81.415 1.00 18.37  ? 33  ILE B C     1 
ATOM   1709 O O     . ILE D 3 33  ? -87.570  46.377 81.373 1.00 24.02  ? 33  ILE B O     1 
ATOM   1710 C CB    . ILE D 3 33  ? -84.740  45.478 80.111 1.00 15.77  ? 33  ILE B CB    1 
ATOM   1711 C CG1   . ILE D 3 33  ? -84.803  46.977 79.873 1.00 12.64  ? 33  ILE B CG1   1 
ATOM   1712 C CG2   . ILE D 3 33  ? -83.922  44.784 79.066 1.00 25.07  ? 33  ILE B CG2   1 
ATOM   1713 C CD1   . ILE D 3 33  ? -83.516  47.666 80.226 1.00 33.47  ? 33  ILE B CD1   1 
ATOM   1714 N N     . SER D 3 34  ? -86.512  44.767 82.532 1.00 19.52  ? 34  SER B N     1 
ATOM   1715 C CA    . SER D 3 34  ? -87.023  45.189 83.824 1.00 16.32  ? 34  SER B CA    1 
ATOM   1716 C C     . SER D 3 34  ? -86.170  46.385 84.250 1.00 10.88  ? 34  SER B C     1 
ATOM   1717 O O     . SER D 3 34  ? -85.141  46.663 83.638 1.00 21.91  ? 34  SER B O     1 
ATOM   1718 C CB    . SER D 3 34  ? -86.876  44.055 84.836 1.00 25.25  ? 34  SER B CB    1 
ATOM   1719 O OG    . SER D 3 34  ? -85.527  43.619 84.927 1.00 19.90  ? 34  SER B OG    1 
ATOM   1720 N N     . SER D 3 35  ? -86.600  47.099 85.283 1.00 22.13  ? 35  SER B N     1 
ATOM   1721 C CA    . SER D 3 35  ? -85.848  48.253 85.771 1.00 21.57  ? 35  SER B CA    1 
ATOM   1722 C C     . SER D 3 35  ? -84.725  47.762 86.681 1.00 23.63  ? 35  SER B C     1 
ATOM   1723 O O     . SER D 3 35  ? -84.873  47.731 87.903 1.00 29.84  ? 35  SER B O     1 
ATOM   1724 C CB    . SER D 3 35  ? -86.773  49.188 86.547 1.00 5.54   ? 35  SER B CB    1 
ATOM   1725 O OG    . SER D 3 35  ? -86.049  50.292 87.066 1.00 67.69  ? 35  SER B OG    1 
ATOM   1726 N N     . ASN D 3 36  ? -83.608  47.374 86.073 1.00 23.79  ? 36  ASN B N     1 
ATOM   1727 C CA    . ASN D 3 36  ? -82.458  46.851 86.803 1.00 12.32  ? 36  ASN B CA    1 
ATOM   1728 C C     . ASN D 3 36  ? -81.203  47.167 86.024 1.00 20.85  ? 36  ASN B C     1 
ATOM   1729 O O     . ASN D 3 36  ? -81.255  47.730 84.930 1.00 26.49  ? 36  ASN B O     1 
ATOM   1730 C CB    . ASN D 3 36  ? -82.510  45.322 86.897 1.00 18.79  ? 36  ASN B CB    1 
ATOM   1731 C CG    . ASN D 3 36  ? -83.612  44.814 87.784 1.00 13.44  ? 36  ASN B CG    1 
ATOM   1732 O OD1   . ASN D 3 36  ? -83.392  44.541 88.960 1.00 30.49  ? 36  ASN B OD1   1 
ATOM   1733 N ND2   . ASN D 3 36  ? -84.803  44.655 87.221 1.00 17.55  ? 36  ASN B ND2   1 
ATOM   1734 N N     . SER D 3 37  ? -80.072  46.777 86.599 1.00 20.12  ? 37  SER B N     1 
ATOM   1735 C CA    . SER D 3 37  ? -78.795  46.939 85.938 1.00 16.53  ? 37  SER B CA    1 
ATOM   1736 C C     . SER D 3 37  ? -78.961  45.892 84.842 1.00 24.59  ? 37  SER B C     1 
ATOM   1737 O O     . SER D 3 37  ? -79.644  44.885 85.045 1.00 23.31  ? 37  SER B O     1 
ATOM   1738 C CB    . SER D 3 37  ? -77.656  46.547 86.882 1.00 21.99  ? 37  SER B CB    1 
ATOM   1739 O OG    . SER D 3 37  ? -77.760  45.184 87.267 1.00 18.93  ? 37  SER B OG    1 
ATOM   1740 N N     . ARG D 3 38  ? -78.366  46.111 83.681 1.00 18.12  ? 38  ARG B N     1 
ATOM   1741 C CA    . ARG D 3 38  ? -78.533  45.140 82.617 1.00 19.91  ? 38  ARG B CA    1 
ATOM   1742 C C     . ARG D 3 38  ? -77.995  43.770 83.003 1.00 19.20  ? 38  ARG B C     1 
ATOM   1743 O O     . ARG D 3 38  ? -78.398  42.748 82.442 1.00 28.58  ? 38  ARG B O     1 
ATOM   1744 C CB    . ARG D 3 38  ? -77.906  45.675 81.324 1.00 2.34   ? 38  ARG B CB    1 
ATOM   1745 C CG    . ARG D 3 38  ? -78.805  46.768 80.733 1.00 17.10  ? 38  ARG B CG    1 
ATOM   1746 C CD    . ARG D 3 38  ? -78.665  46.933 79.255 1.00 16.03  ? 38  ARG B CD    1 
ATOM   1747 N NE    . ARG D 3 38  ? -79.575  46.087 78.492 1.00 21.47  ? 38  ARG B NE    1 
ATOM   1748 C CZ    . ARG D 3 38  ? -80.578  46.544 77.750 1.00 20.97  ? 38  ARG B CZ    1 
ATOM   1749 N NH1   . ARG D 3 38  ? -80.817  47.845 77.661 1.00 20.58  ? 38  ARG B NH1   1 
ATOM   1750 N NH2   . ARG D 3 38  ? -81.322  45.699 77.060 1.00 35.81  ? 38  ARG B NH2   1 
ATOM   1751 N N     . SER D 3 39  ? -77.115  43.744 83.994 1.00 20.30  ? 39  SER B N     1 
ATOM   1752 C CA    . SER D 3 39  ? -76.545  42.485 84.447 1.00 17.44  ? 39  SER B CA    1 
ATOM   1753 C C     . SER D 3 39  ? -77.541  41.700 85.290 1.00 13.80  ? 39  SER B C     1 
ATOM   1754 O O     . SER D 3 39  ? -77.433  40.482 85.395 1.00 24.24  ? 39  SER B O     1 
ATOM   1755 C CB    . SER D 3 39  ? -75.261  42.734 85.257 1.00 11.77  ? 39  SER B CB    1 
ATOM   1756 O OG    . SER D 3 39  ? -75.552  43.105 86.595 1.00 18.09  ? 39  SER B OG    1 
ATOM   1757 N N     . GLN D 3 40  ? -78.510  42.389 85.886 1.00 14.81  ? 40  GLN B N     1 
ATOM   1758 C CA    . GLN D 3 40  ? -79.503  41.726 86.735 1.00 16.36  ? 40  GLN B CA    1 
ATOM   1759 C C     . GLN D 3 40  ? -80.923  41.816 86.190 1.00 17.53  ? 40  GLN B C     1 
ATOM   1760 O O     . GLN D 3 40  ? -81.865  41.361 86.831 1.00 21.95  ? 40  GLN B O     1 
ATOM   1761 C CB    . GLN D 3 40  ? -79.481  42.334 88.145 1.00 2.00   ? 40  GLN B CB    1 
ATOM   1762 C CG    . GLN D 3 40  ? -78.162  42.161 88.858 1.00 16.15  ? 40  GLN B CG    1 
ATOM   1763 C CD    . GLN D 3 40  ? -78.202  42.643 90.289 1.00 21.09  ? 40  GLN B CD    1 
ATOM   1764 O OE1   . GLN D 3 40  ? -78.791  43.683 90.592 1.00 22.82  ? 40  GLN B OE1   1 
ATOM   1765 N NE2   . GLN D 3 40  ? -77.569  41.890 91.184 1.00 19.82  ? 40  GLN B NE2   1 
ATOM   1766 N N     . ALA D 3 41  ? -81.077  42.384 85.003 1.00 17.65  ? 41  ALA B N     1 
ATOM   1767 C CA    . ALA D 3 41  ? -82.402  42.561 84.428 1.00 18.38  ? 41  ALA B CA    1 
ATOM   1768 C C     . ALA D 3 41  ? -83.073  41.320 83.878 1.00 17.95  ? 41  ALA B C     1 
ATOM   1769 O O     . ALA D 3 41  ? -82.477  40.256 83.768 1.00 23.51  ? 41  ALA B O     1 
ATOM   1770 C CB    . ALA D 3 41  ? -82.348  43.617 83.339 1.00 11.65  ? 41  ALA B CB    1 
ATOM   1771 N N     . TYR D 3 42  ? -84.350  41.486 83.565 1.00 20.97  ? 42  TYR B N     1 
ATOM   1772 C CA    . TYR D 3 42  ? -85.157  40.451 82.950 1.00 15.77  ? 42  TYR B CA    1 
ATOM   1773 C C     . TYR D 3 42  ? -85.191  41.013 81.541 1.00 18.46  ? 42  TYR B C     1 
ATOM   1774 O O     . TYR D 3 42  ? -85.631  42.145 81.341 1.00 18.46  ? 42  TYR B O     1 
ATOM   1775 C CB    . TYR D 3 42  ? -86.578  40.471 83.489 1.00 15.77  ? 42  TYR B CB    1 
ATOM   1776 C CG    . TYR D 3 42  ? -86.800  39.675 84.737 1.00 17.60  ? 42  TYR B CG    1 
ATOM   1777 C CD1   . TYR D 3 42  ? -86.518  40.215 85.986 1.00 13.05  ? 42  TYR B CD1   1 
ATOM   1778 C CD2   . TYR D 3 42  ? -87.351  38.396 84.677 1.00 19.78  ? 42  TYR B CD2   1 
ATOM   1779 C CE1   . TYR D 3 42  ? -86.784  39.502 87.153 1.00 17.24  ? 42  TYR B CE1   1 
ATOM   1780 C CE2   . TYR D 3 42  ? -87.620  37.675 85.830 1.00 16.25  ? 42  TYR B CE2   1 
ATOM   1781 C CZ    . TYR D 3 42  ? -87.337  38.234 87.067 1.00 27.74  ? 42  TYR B CZ    1 
ATOM   1782 O OH    . TYR D 3 42  ? -87.618  37.527 88.214 1.00 32.87  ? 42  TYR B OH    1 
ATOM   1783 N N     . LYS D 3 43  ? -84.715  40.262 80.565 1.00 18.87  ? 43  LYS B N     1 
ATOM   1784 C CA    . LYS D 3 43  ? -84.732  40.781 79.212 1.00 12.52  ? 43  LYS B CA    1 
ATOM   1785 C C     . LYS D 3 43  ? -85.578  39.905 78.318 1.00 19.31  ? 43  LYS B C     1 
ATOM   1786 O O     . LYS D 3 43  ? -85.617  38.679 78.480 1.00 14.43  ? 43  LYS B O     1 
ATOM   1787 C CB    . LYS D 3 43  ? -83.312  40.864 78.653 1.00 8.97   ? 43  LYS B CB    1 
ATOM   1788 C CG    . LYS D 3 43  ? -83.221  41.550 77.304 1.00 14.34  ? 43  LYS B CG    1 
ATOM   1789 C CD    . LYS D 3 43  ? -81.815  42.024 77.019 1.00 23.71  ? 43  LYS B CD    1 
ATOM   1790 C CE    . LYS D 3 43  ? -80.892  40.868 76.664 1.00 21.39  ? 43  LYS B CE    1 
ATOM   1791 N NZ    . LYS D 3 43  ? -80.030  41.207 75.495 1.00 33.99  ? 43  LYS B NZ    1 
ATOM   1792 N N     . VAL D 3 44  ? -86.276  40.545 77.389 1.00 10.14  ? 44  VAL B N     1 
ATOM   1793 C CA    . VAL D 3 44  ? -87.092  39.827 76.432 1.00 14.37  ? 44  VAL B CA    1 
ATOM   1794 C C     . VAL D 3 44  ? -86.866  40.469 75.076 1.00 16.17  ? 44  VAL B C     1 
ATOM   1795 O O     . VAL D 3 44  ? -86.897  41.691 74.961 1.00 24.26  ? 44  VAL B O     1 
ATOM   1796 C CB    . VAL D 3 44  ? -88.594  39.912 76.766 1.00 10.80  ? 44  VAL B CB    1 
ATOM   1797 C CG1   . VAL D 3 44  ? -89.397  39.268 75.648 1.00 3.72   ? 44  VAL B CG1   1 
ATOM   1798 C CG2   . VAL D 3 44  ? -88.888  39.202 78.078 1.00 12.57  ? 44  VAL B CG2   1 
ATOM   1799 N N     . THR D 3 45  ? -86.600  39.653 74.060 1.00 15.69  ? 45  THR B N     1 
ATOM   1800 C CA    . THR D 3 45  ? -86.423  40.169 72.706 1.00 13.94  ? 45  THR B CA    1 
ATOM   1801 C C     . THR D 3 45  ? -87.203  39.284 71.763 1.00 15.18  ? 45  THR B C     1 
ATOM   1802 O O     . THR D 3 45  ? -87.354  38.085 71.998 1.00 21.57  ? 45  THR B O     1 
ATOM   1803 C CB    . THR D 3 45  ? -84.954  40.203 72.259 1.00 9.25   ? 45  THR B CB    1 
ATOM   1804 O OG1   . THR D 3 45  ? -84.419  38.872 72.234 1.00 27.39  ? 45  THR B OG1   1 
ATOM   1805 C CG2   . THR D 3 45  ? -84.150  41.076 73.202 1.00 16.70  ? 45  THR B CG2   1 
ATOM   1806 N N     . CYS D 3 46  ? -87.715  39.886 70.700 1.00 19.38  ? 46  CYS B N     1 
ATOM   1807 C CA    . CYS D 3 46  ? -88.503  39.155 69.727 1.00 16.55  ? 46  CYS B CA    1 
ATOM   1808 C C     . CYS D 3 46  ? -88.306  39.729 68.325 1.00 21.34  ? 46  CYS B C     1 
ATOM   1809 O O     . CYS D 3 46  ? -88.131  40.937 68.157 1.00 17.66  ? 46  CYS B O     1 
ATOM   1810 C CB    . CYS D 3 46  ? -89.975  39.233 70.123 1.00 17.34  ? 46  CYS B CB    1 
ATOM   1811 S SG    . CYS D 3 46  ? -91.128  38.628 68.880 1.00 23.73  ? 46  CYS B SG    1 
ATOM   1812 N N     . SER D 3 47  ? -88.326  38.861 67.321 1.00 24.29  ? 47  SER B N     1 
ATOM   1813 C CA    . SER D 3 47  ? -88.165  39.303 65.942 1.00 24.29  ? 47  SER B CA    1 
ATOM   1814 C C     . SER D 3 47  ? -88.776  38.290 64.978 1.00 23.19  ? 47  SER B C     1 
ATOM   1815 O O     . SER D 3 47  ? -88.897  37.109 65.307 1.00 23.57  ? 47  SER B O     1 
ATOM   1816 C CB    . SER D 3 47  ? -86.681  39.516 65.630 1.00 7.84   ? 47  SER B CB    1 
ATOM   1817 O OG    . SER D 3 47  ? -86.018  38.286 65.429 1.00 32.36  ? 47  SER B OG    1 
ATOM   1818 N N     . VAL D 3 48  ? -89.192  38.762 63.803 1.00 25.97  ? 48  VAL B N     1 
ATOM   1819 C CA    . VAL D 3 48  ? -89.780  37.886 62.792 1.00 23.79  ? 48  VAL B CA    1 
ATOM   1820 C C     . VAL D 3 48  ? -89.081  38.066 61.472 1.00 25.63  ? 48  VAL B C     1 
ATOM   1821 O O     . VAL D 3 48  ? -88.703  39.176 61.098 1.00 42.82  ? 48  VAL B O     1 
ATOM   1822 C CB    . VAL D 3 48  ? -91.262  38.176 62.508 1.00 19.44  ? 48  VAL B CB    1 
ATOM   1823 C CG1   . VAL D 3 48  ? -92.004  36.860 62.325 1.00 14.86  ? 48  VAL B CG1   1 
ATOM   1824 C CG2   . VAL D 3 48  ? -91.868  39.010 63.613 1.00 39.62  ? 48  VAL B CG2   1 
ATOM   1825 N N     . ARG D 3 49  ? -88.924  36.963 60.760 1.00 27.18  ? 49  ARG B N     1 
ATOM   1826 C CA    . ARG D 3 49  ? -88.287  36.982 59.458 1.00 17.96  ? 49  ARG B CA    1 
ATOM   1827 C C     . ARG D 3 49  ? -88.862  35.843 58.641 1.00 22.22  ? 49  ARG B C     1 
ATOM   1828 O O     . ARG D 3 49  ? -89.449  34.906 59.188 1.00 20.70  ? 49  ARG B O     1 
ATOM   1829 C CB    . ARG D 3 49  ? -86.769  36.808 59.600 1.00 18.02  ? 49  ARG B CB    1 
ATOM   1830 C CG    . ARG D 3 49  ? -86.298  35.356 59.748 1.00 24.33  ? 49  ARG B CG    1 
ATOM   1831 C CD    . ARG D 3 49  ? -84.800  35.283 60.055 1.00 39.59  ? 49  ARG B CD    1 
ATOM   1832 N NE    . ARG D 3 49  ? -84.411  34.081 60.802 1.00 60.89  ? 49  ARG B NE    1 
ATOM   1833 C CZ    . ARG D 3 49  ? -84.679  33.864 62.091 1.00 63.48  ? 49  ARG B CZ    1 
ATOM   1834 N NH1   . ARG D 3 49  ? -85.348  34.766 62.808 1.00 51.15  ? 49  ARG B NH1   1 
ATOM   1835 N NH2   . ARG D 3 49  ? -84.264  32.743 62.674 1.00 60.20  ? 49  ARG B NH2   1 
ATOM   1836 N N     . GLN D 3 50  ? -88.730  35.944 57.326 1.00 24.37  ? 50  GLN B N     1 
ATOM   1837 C CA    . GLN D 3 50  ? -89.187  34.875 56.460 1.00 25.00  ? 50  GLN B CA    1 
ATOM   1838 C C     . GLN D 3 50  ? -87.919  34.043 56.294 1.00 25.77  ? 50  GLN B C     1 
ATOM   1839 O O     . GLN D 3 50  ? -87.015  34.444 55.568 1.00 32.03  ? 50  GLN B O     1 
ATOM   1840 C CB    . GLN D 3 50  ? -89.634  35.436 55.121 1.00 14.68  ? 50  GLN B CB    1 
ATOM   1841 C CG    . GLN D 3 50  ? -89.935  34.373 54.101 1.00 29.88  ? 50  GLN B CG    1 
ATOM   1842 C CD    . GLN D 3 50  ? -91.289  34.549 53.478 1.00 33.10  ? 50  GLN B CD    1 
ATOM   1843 O OE1   . GLN D 3 50  ? -91.948  35.563 53.686 1.00 58.61  ? 50  GLN B OE1   1 
ATOM   1844 N NE2   . GLN D 3 50  ? -91.718  33.559 52.707 1.00 57.99  ? 50  GLN B NE2   1 
ATOM   1845 N N     . SER D 3 51  ? -87.848  32.908 56.989 1.00 29.83  ? 51  SER B N     1 
ATOM   1846 C CA    . SER D 3 51  ? -86.668  32.042 56.961 1.00 32.23  ? 51  SER B CA    1 
ATOM   1847 C C     . SER D 3 51  ? -86.422  31.354 55.628 1.00 33.59  ? 51  SER B C     1 
ATOM   1848 O O     . SER D 3 51  ? -85.276  31.120 55.238 1.00 48.22  ? 51  SER B O     1 
ATOM   1849 C CB    . SER D 3 51  ? -86.764  30.984 58.065 1.00 22.82  ? 51  SER B CB    1 
ATOM   1850 O OG    . SER D 3 51  ? -88.040  30.368 58.073 1.00 48.21  ? 51  SER B OG    1 
ATOM   1851 N N     . SER D 3 52  ? -87.504  31.026 54.935 1.00 36.87  ? 52  SER B N     1 
ATOM   1852 C CA    . SER D 3 52  ? -87.419  30.363 53.644 1.00 23.45  ? 52  SER B CA    1 
ATOM   1853 C C     . SER D 3 52  ? -88.657  30.707 52.819 1.00 29.58  ? 52  SER B C     1 
ATOM   1854 O O     . SER D 3 52  ? -89.486  31.518 53.235 1.00 40.19  ? 52  SER B O     1 
ATOM   1855 C CB    . SER D 3 52  ? -87.292  28.844 53.842 1.00 17.45  ? 52  SER B CB    1 
ATOM   1856 O OG    . SER D 3 52  ? -88.525  28.231 54.184 1.00 39.55  ? 52  SER B OG    1 
ATOM   1857 N N     . ALA D 3 53  ? -88.786  30.104 51.647 1.00 35.50  ? 53  ALA B N     1 
ATOM   1858 C CA    . ALA D 3 53  ? -89.934  30.384 50.797 1.00 31.60  ? 53  ALA B CA    1 
ATOM   1859 C C     . ALA D 3 53  ? -91.218  29.868 51.430 1.00 37.28  ? 53  ALA B C     1 
ATOM   1860 O O     . ALA D 3 53  ? -92.281  30.467 51.278 1.00 43.15  ? 53  ALA B O     1 
ATOM   1861 C CB    . ALA D 3 53  ? -89.733  29.742 49.443 1.00 33.98  ? 53  ALA B CB    1 
ATOM   1862 N N     . GLN D 3 54  ? -91.104  28.760 52.152 1.00 36.88  ? 54  GLN B N     1 
ATOM   1863 C CA    . GLN D 3 54  ? -92.251  28.135 52.786 1.00 38.68  ? 54  GLN B CA    1 
ATOM   1864 C C     . GLN D 3 54  ? -92.570  28.603 54.204 1.00 35.54  ? 54  GLN B C     1 
ATOM   1865 O O     . GLN D 3 54  ? -93.729  28.576 54.627 1.00 28.85  ? 54  GLN B O     1 
ATOM   1866 C CB    . GLN D 3 54  ? -92.049  26.618 52.798 1.00 59.47  ? 54  GLN B CB    1 
ATOM   1867 C CG    . GLN D 3 54  ? -92.024  25.986 51.407 1.00 95.65  ? 54  GLN B CG    1 
ATOM   1868 C CD    . GLN D 3 54  ? -93.294  26.260 50.598 1.00 100.00 ? 54  GLN B CD    1 
ATOM   1869 O OE1   . GLN D 3 54  ? -94.365  26.493 51.161 1.00 100.00 ? 54  GLN B OE1   1 
ATOM   1870 N NE2   . GLN D 3 54  ? -93.174  26.232 49.272 1.00 100.00 ? 54  GLN B NE2   1 
ATOM   1871 N N     . ASN D 3 55  ? -91.559  29.050 54.937 1.00 27.63  ? 55  ASN B N     1 
ATOM   1872 C CA    . ASN D 3 55  ? -91.790  29.435 56.318 1.00 24.81  ? 55  ASN B CA    1 
ATOM   1873 C C     . ASN D 3 55  ? -91.448  30.838 56.764 1.00 23.66  ? 55  ASN B C     1 
ATOM   1874 O O     . ASN D 3 55  ? -90.684  31.555 56.122 1.00 25.25  ? 55  ASN B O     1 
ATOM   1875 C CB    . ASN D 3 55  ? -91.033  28.483 57.247 1.00 23.63  ? 55  ASN B CB    1 
ATOM   1876 C CG    . ASN D 3 55  ? -91.346  27.033 56.987 1.00 23.11  ? 55  ASN B CG    1 
ATOM   1877 O OD1   . ASN D 3 55  ? -92.508  26.619 56.994 1.00 43.43  ? 55  ASN B OD1   1 
ATOM   1878 N ND2   . ASN D 3 55  ? -90.304  26.243 56.768 1.00 30.74  ? 55  ASN B ND2   1 
ATOM   1879 N N     . ARG D 3 56  ? -92.031  31.193 57.905 1.00 20.10  ? 56  ARG B N     1 
ATOM   1880 C CA    . ARG D 3 56  ? -91.779  32.452 58.585 1.00 18.62  ? 56  ARG B CA    1 
ATOM   1881 C C     . ARG D 3 56  ? -91.253  31.958 59.929 1.00 21.35  ? 56  ARG B C     1 
ATOM   1882 O O     . ARG D 3 56  ? -91.635  30.880 60.387 1.00 25.57  ? 56  ARG B O     1 
ATOM   1883 C CB    . ARG D 3 56  ? -93.062  33.245 58.770 1.00 6.90   ? 56  ARG B CB    1 
ATOM   1884 C CG    . ARG D 3 56  ? -93.149  34.424 57.838 1.00 16.57  ? 56  ARG B CG    1 
ATOM   1885 C CD    . ARG D 3 56  ? -94.478  35.103 57.974 1.00 9.96   ? 56  ARG B CD    1 
ATOM   1886 N NE    . ARG D 3 56  ? -94.519  36.019 59.113 1.00 35.43  ? 56  ARG B NE    1 
ATOM   1887 C CZ    . ARG D 3 56  ? -95.273  35.835 60.193 1.00 30.39  ? 56  ARG B CZ    1 
ATOM   1888 N NH1   . ARG D 3 56  ? -96.052  34.767 60.290 1.00 17.50  ? 56  ARG B NH1   1 
ATOM   1889 N NH2   . ARG D 3 56  ? -95.269  36.733 61.170 1.00 35.93  ? 56  ARG B NH2   1 
ATOM   1890 N N     . LYS D 3 57  ? -90.378  32.722 60.565 1.00 22.09  ? 57  LYS B N     1 
ATOM   1891 C CA    . LYS D 3 57  ? -89.815  32.278 61.829 1.00 13.13  ? 57  LYS B CA    1 
ATOM   1892 C C     . LYS D 3 57  ? -89.751  33.372 62.889 1.00 19.58  ? 57  LYS B C     1 
ATOM   1893 O O     . LYS D 3 57  ? -89.229  34.462 62.644 1.00 26.87  ? 57  LYS B O     1 
ATOM   1894 C CB    . LYS D 3 57  ? -88.415  31.723 61.570 1.00 14.96  ? 57  LYS B CB    1 
ATOM   1895 C CG    . LYS D 3 57  ? -87.895  30.770 62.615 1.00 29.24  ? 57  LYS B CG    1 
ATOM   1896 C CD    . LYS D 3 57  ? -86.448  30.374 62.333 1.00 43.05  ? 57  LYS B CD    1 
ATOM   1897 C CE    . LYS D 3 57  ? -86.369  29.167 61.405 1.00 48.28  ? 57  LYS B CE    1 
ATOM   1898 N NZ    . LYS D 3 57  ? -85.036  28.502 61.493 1.00 63.99  ? 57  LYS B NZ    1 
ATOM   1899 N N     . TYR D 3 58  ? -90.303  33.080 64.063 1.00 16.72  ? 58  TYR B N     1 
ATOM   1900 C CA    . TYR D 3 58  ? -90.267  34.025 65.174 1.00 12.57  ? 58  TYR B CA    1 
ATOM   1901 C C     . TYR D 3 58  ? -89.131  33.575 66.073 1.00 11.61  ? 58  TYR B C     1 
ATOM   1902 O O     . TYR D 3 58  ? -89.051  32.404 66.434 1.00 17.99  ? 58  TYR B O     1 
ATOM   1903 C CB    . TYR D 3 58  ? -91.554  33.984 65.998 1.00 7.30   ? 58  TYR B CB    1 
ATOM   1904 C CG    . TYR D 3 58  ? -92.707  34.775 65.430 1.00 15.45  ? 58  TYR B CG    1 
ATOM   1905 C CD1   . TYR D 3 58  ? -92.872  36.124 65.730 1.00 11.82  ? 58  TYR B CD1   1 
ATOM   1906 C CD2   . TYR D 3 58  ? -93.645  34.168 64.599 1.00 17.66  ? 58  TYR B CD2   1 
ATOM   1907 C CE1   . TYR D 3 58  ? -93.949  36.849 65.210 1.00 19.34  ? 58  TYR B CE1   1 
ATOM   1908 C CE2   . TYR D 3 58  ? -94.720  34.881 64.078 1.00 17.84  ? 58  TYR B CE2   1 
ATOM   1909 C CZ    . TYR D 3 58  ? -94.867  36.217 64.383 1.00 18.70  ? 58  TYR B CZ    1 
ATOM   1910 O OH    . TYR D 3 58  ? -95.931  36.908 63.851 1.00 22.78  ? 58  TYR B OH    1 
ATOM   1911 N N     . THR D 3 59  ? -88.234  34.489 66.411 1.00 21.57  ? 59  THR B N     1 
ATOM   1912 C CA    . THR D 3 59  ? -87.149  34.152 67.314 1.00 11.25  ? 59  THR B CA    1 
ATOM   1913 C C     . THR D 3 59  ? -87.401  34.982 68.568 1.00 16.55  ? 59  THR B C     1 
ATOM   1914 O O     . THR D 3 59  ? -87.409  36.216 68.524 1.00 24.12  ? 59  THR B O     1 
ATOM   1915 C CB    . THR D 3 59  ? -85.783  34.498 66.726 1.00 13.60  ? 59  THR B CB    1 
ATOM   1916 O OG1   . THR D 3 59  ? -85.469  33.581 65.674 1.00 20.58  ? 59  THR B OG1   1 
ATOM   1917 C CG2   . THR D 3 59  ? -84.717  34.390 67.793 1.00 7.82   ? 59  THR B CG2   1 
ATOM   1918 N N     . ILE D 3 60  ? -87.638  34.287 69.674 1.00 17.29  ? 60  ILE B N     1 
ATOM   1919 C CA    . ILE D 3 60  ? -87.911  34.917 70.958 1.00 18.99  ? 60  ILE B CA    1 
ATOM   1920 C C     . ILE D 3 60  ? -86.864  34.496 71.971 1.00 15.23  ? 60  ILE B C     1 
ATOM   1921 O O     . ILE D 3 60  ? -86.607  33.311 72.145 1.00 26.59  ? 60  ILE B O     1 
ATOM   1922 C CB    . ILE D 3 60  ? -89.276  34.490 71.491 1.00 15.17  ? 60  ILE B CB    1 
ATOM   1923 C CG1   . ILE D 3 60  ? -90.359  34.923 70.509 1.00 19.87  ? 60  ILE B CG1   1 
ATOM   1924 C CG2   . ILE D 3 60  ? -89.514  35.091 72.858 1.00 7.30   ? 60  ILE B CG2   1 
ATOM   1925 C CD1   . ILE D 3 60  ? -91.598  34.082 70.583 1.00 19.64  ? 60  ILE B CD1   1 
ATOM   1926 N N     . LYS D 3 61  ? -86.256  35.465 72.636 1.00 13.21  ? 61  LYS B N     1 
ATOM   1927 C CA    . LYS D 3 61  ? -85.250  35.158 73.637 1.00 12.17  ? 61  LYS B CA    1 
ATOM   1928 C C     . LYS D 3 61  ? -85.606  35.824 74.962 1.00 18.46  ? 61  LYS B C     1 
ATOM   1929 O O     . LYS D 3 61  ? -86.099  36.954 74.994 1.00 26.22  ? 61  LYS B O     1 
ATOM   1930 C CB    . LYS D 3 61  ? -83.882  35.630 73.166 1.00 8.64   ? 61  LYS B CB    1 
ATOM   1931 C CG    . LYS D 3 61  ? -83.374  34.896 71.945 1.00 18.21  ? 61  LYS B CG    1 
ATOM   1932 C CD    . LYS D 3 61  ? -82.136  35.567 71.373 1.00 22.93  ? 61  LYS B CD    1 
ATOM   1933 C CE    . LYS D 3 61  ? -81.425  34.670 70.380 1.00 23.85  ? 61  LYS B CE    1 
ATOM   1934 N NZ    . LYS D 3 61  ? -80.317  33.905 71.019 1.00 51.71  ? 61  LYS B NZ    1 
ATOM   1935 N N     . VAL D 3 62  ? -85.373  35.108 76.054 1.00 13.23  ? 62  VAL B N     1 
ATOM   1936 C CA    . VAL D 3 62  ? -85.661  35.634 77.375 1.00 14.40  ? 62  VAL B CA    1 
ATOM   1937 C C     . VAL D 3 62  ? -84.486  35.358 78.293 1.00 13.93  ? 62  VAL B C     1 
ATOM   1938 O O     . VAL D 3 62  ? -83.860  34.305 78.213 1.00 24.16  ? 62  VAL B O     1 
ATOM   1939 C CB    . VAL D 3 62  ? -86.919  34.975 77.995 1.00 12.70  ? 62  VAL B CB    1 
ATOM   1940 C CG1   . VAL D 3 62  ? -87.155  35.525 79.395 1.00 2.00   ? 62  VAL B CG1   1 
ATOM   1941 C CG2   . VAL D 3 62  ? -88.135  35.236 77.117 1.00 10.81  ? 62  VAL B CG2   1 
ATOM   1942 N N     . GLU D 3 63  ? -84.183  36.320 79.154 1.00 19.07  ? 63  GLU B N     1 
ATOM   1943 C CA    . GLU D 3 63  ? -83.105  36.176 80.121 1.00 14.40  ? 63  GLU B CA    1 
ATOM   1944 C C     . GLU D 3 63  ? -83.716  36.388 81.503 1.00 17.35  ? 63  GLU B C     1 
ATOM   1945 O O     . GLU D 3 63  ? -84.409  37.381 81.738 1.00 21.81  ? 63  GLU B O     1 
ATOM   1946 C CB    . GLU D 3 63  ? -82.027  37.219 79.876 1.00 10.12  ? 63  GLU B CB    1 
ATOM   1947 C CG    . GLU D 3 63  ? -81.030  36.853 78.799 1.00 13.72  ? 63  GLU B CG    1 
ATOM   1948 C CD    . GLU D 3 63  ? -79.989  37.936 78.616 1.00 25.66  ? 63  GLU B CD    1 
ATOM   1949 O OE1   . GLU D 3 63  ? -79.667  38.615 79.615 1.00 25.66  ? 63  GLU B OE1   1 
ATOM   1950 O OE2   . GLU D 3 63  ? -79.499  38.116 77.482 1.00 27.46  ? 63  GLU B OE2   1 
ATOM   1951 N N     . VAL D 3 64  ? -83.475  35.449 82.410 1.00 17.81  ? 64  VAL B N     1 
ATOM   1952 C CA    . VAL D 3 64  ? -84.015  35.544 83.762 1.00 19.12  ? 64  VAL B CA    1 
ATOM   1953 C C     . VAL D 3 64  ? -82.872  35.531 84.761 1.00 21.95  ? 64  VAL B C     1 
ATOM   1954 O O     . VAL D 3 64  ? -81.988  34.674 84.698 1.00 30.40  ? 64  VAL B O     1 
ATOM   1955 C CB    . VAL D 3 64  ? -84.964  34.371 84.068 1.00 13.70  ? 64  VAL B CB    1 
ATOM   1956 C CG1   . VAL D 3 64  ? -85.472  34.470 85.491 1.00 18.71  ? 64  VAL B CG1   1 
ATOM   1957 C CG2   . VAL D 3 64  ? -86.121  34.381 83.093 1.00 10.93  ? 64  VAL B CG2   1 
ATOM   1958 N N     . PRO D 3 65  ? -82.872  36.487 85.700 1.00 21.06  ? 65  PRO B N     1 
ATOM   1959 C CA    . PRO D 3 65  ? -81.815  36.576 86.712 1.00 18.41  ? 65  PRO B CA    1 
ATOM   1960 C C     . PRO D 3 65  ? -81.972  35.571 87.846 1.00 13.29  ? 65  PRO B C     1 
ATOM   1961 O O     . PRO D 3 65  ? -83.091  35.210 88.200 1.00 27.18  ? 65  PRO B O     1 
ATOM   1962 C CB    . PRO D 3 65  ? -81.947  38.003 87.221 1.00 10.48  ? 65  PRO B CB    1 
ATOM   1963 C CG    . PRO D 3 65  ? -83.424  38.260 87.138 1.00 6.86   ? 65  PRO B CG    1 
ATOM   1964 C CD    . PRO D 3 65  ? -83.875  37.556 85.870 1.00 20.92  ? 65  PRO B CD    1 
ATOM   1965 N N     . LYS D 3 66  ? -80.853  35.112 88.402 1.00 15.79  ? 66  LYS B N     1 
ATOM   1966 C CA    . LYS D 3 66  ? -80.902  34.199 89.539 1.00 16.32  ? 66  LYS B CA    1 
ATOM   1967 C C     . LYS D 3 66  ? -81.098  35.160 90.706 1.00 18.49  ? 66  LYS B C     1 
ATOM   1968 O O     . LYS D 3 66  ? -80.275  36.052 90.917 1.00 22.66  ? 66  LYS B O     1 
ATOM   1969 C CB    . LYS D 3 66  ? -79.585  33.437 89.711 1.00 10.60  ? 66  LYS B CB    1 
ATOM   1970 C CG    . LYS D 3 66  ? -79.533  32.629 91.009 1.00 10.79  ? 66  LYS B CG    1 
ATOM   1971 C CD    . LYS D 3 66  ? -78.155  32.056 91.276 1.00 15.27  ? 66  LYS B CD    1 
ATOM   1972 C CE    . LYS D 3 66  ? -77.940  31.813 92.760 1.00 10.59  ? 66  LYS B CE    1 
ATOM   1973 N NZ    . LYS D 3 66  ? -79.139  31.211 93.407 1.00 12.73  ? 66  LYS B NZ    1 
ATOM   1974 N N     . VAL D 3 67  ? -82.179  34.988 91.457 1.00 16.62  ? 67  VAL B N     1 
ATOM   1975 C CA    . VAL D 3 67  ? -82.473  35.894 92.557 1.00 16.46  ? 67  VAL B CA    1 
ATOM   1976 C C     . VAL D 3 67  ? -82.004  35.456 93.942 1.00 14.35  ? 67  VAL B C     1 
ATOM   1977 O O     . VAL D 3 67  ? -81.630  36.295 94.761 1.00 17.14  ? 67  VAL B O     1 
ATOM   1978 C CB    . VAL D 3 67  ? -83.978  36.189 92.602 1.00 10.18  ? 67  VAL B CB    1 
ATOM   1979 C CG1   . VAL D 3 67  ? -84.284  37.144 93.724 1.00 29.87  ? 67  VAL B CG1   1 
ATOM   1980 C CG2   . VAL D 3 67  ? -84.412  36.785 91.286 1.00 7.68   ? 67  VAL B CG2   1 
ATOM   1981 N N     . ALA D 3 68  ? -82.015  34.155 94.212 1.00 10.04  ? 68  ALA B N     1 
ATOM   1982 C CA    . ALA D 3 68  ? -81.579  33.661 95.515 1.00 3.63   ? 68  ALA B CA    1 
ATOM   1983 C C     . ALA D 3 68  ? -80.155  34.126 95.840 1.00 11.01  ? 68  ALA B C     1 
ATOM   1984 O O     . ALA D 3 68  ? -79.221  33.854 95.087 1.00 18.80  ? 68  ALA B O     1 
ATOM   1985 C CB    . ALA D 3 68  ? -81.654  32.143 95.544 1.00 3.31   ? 68  ALA B CB    1 
ATOM   1986 N N     . THR D 3 69  ? -80.009  34.816 96.970 1.00 13.15  ? 69  THR B N     1 
ATOM   1987 C CA    . THR D 3 69  ? -78.730  35.354 97.459 1.00 11.24  ? 69  THR B CA    1 
ATOM   1988 C C     . THR D 3 69  ? -78.155  36.476 96.597 1.00 16.97  ? 69  THR B C     1 
ATOM   1989 O O     . THR D 3 69  ? -76.995  36.870 96.760 1.00 22.41  ? 69  THR B O     1 
ATOM   1990 C CB    . THR D 3 69  ? -77.626  34.263 97.625 1.00 4.36   ? 69  THR B CB    1 
ATOM   1991 O OG1   . THR D 3 69  ? -77.040  33.969 96.351 1.00 17.57  ? 69  THR B OG1   1 
ATOM   1992 C CG2   . THR D 3 69  ? -78.192  32.999 98.236 1.00 5.88   ? 69  THR B CG2   1 
ATOM   1993 N N     . GLN D 3 70  ? -78.972  36.995 95.688 1.00 8.85   ? 70  GLN B N     1 
ATOM   1994 C CA    . GLN D 3 70  ? -78.546  38.087 94.823 1.00 17.03  ? 70  GLN B CA    1 
ATOM   1995 C C     . GLN D 3 70  ? -78.291  39.349 95.647 1.00 13.73  ? 70  GLN B C     1 
ATOM   1996 O O     . GLN D 3 70  ? -78.912  39.553 96.691 1.00 22.26  ? 70  GLN B O     1 
ATOM   1997 C CB    . GLN D 3 70  ? -79.625  38.376 93.775 1.00 8.21   ? 70  GLN B CB    1 
ATOM   1998 C CG    . GLN D 3 70  ? -80.034  39.830 93.707 1.00 14.33  ? 70  GLN B CG    1 
ATOM   1999 C CD    . GLN D 3 70  ? -81.168  40.070 92.745 1.00 29.91  ? 70  GLN B CD    1 
ATOM   2000 O OE1   . GLN D 3 70  ? -82.277  40.426 93.147 1.00 40.35  ? 70  GLN B OE1   1 
ATOM   2001 N NE2   . GLN D 3 70  ? -80.898  39.878 91.459 1.00 19.32  ? 70  GLN B NE2   1 
ATOM   2002 N N     . THR D 3 71  ? -77.372  40.185 95.171 1.00 15.92  ? 71  THR B N     1 
ATOM   2003 C CA    . THR D 3 71  ? -77.038  41.456 95.820 1.00 14.69  ? 71  THR B CA    1 
ATOM   2004 C C     . THR D 3 71  ? -77.437  42.553 94.826 1.00 15.25  ? 71  THR B C     1 
ATOM   2005 O O     . THR D 3 71  ? -76.702  42.872 93.891 1.00 19.13  ? 71  THR B O     1 
ATOM   2006 C CB    . THR D 3 71  ? -75.525  41.559 96.124 1.00 14.74  ? 71  THR B CB    1 
ATOM   2007 O OG1   . THR D 3 71  ? -75.190  40.680 97.203 1.00 39.24  ? 71  THR B OG1   1 
ATOM   2008 C CG2   . THR D 3 71  ? -75.156  42.975 96.509 1.00 5.53   ? 71  THR B CG2   1 
ATOM   2009 N N     . VAL D 3 72  ? -78.614  43.121 95.029 1.00 18.29  ? 72  VAL B N     1 
ATOM   2010 C CA    . VAL D 3 72  ? -79.132  44.143 94.134 1.00 19.39  ? 72  VAL B CA    1 
ATOM   2011 C C     . VAL D 3 72  ? -78.166  45.272 93.820 1.00 15.82  ? 72  VAL B C     1 
ATOM   2012 O O     . VAL D 3 72  ? -77.648  45.932 94.720 1.00 27.31  ? 72  VAL B O     1 
ATOM   2013 C CB    . VAL D 3 72  ? -80.423  44.746 94.697 1.00 11.78  ? 72  VAL B CB    1 
ATOM   2014 C CG1   . VAL D 3 72  ? -81.169  45.457 93.606 1.00 12.35  ? 72  VAL B CG1   1 
ATOM   2015 C CG2   . VAL D 3 72  ? -81.291  43.648 95.277 1.00 20.55  ? 72  VAL B CG2   1 
ATOM   2016 N N     . GLY D 3 73  ? -77.937  45.482 92.527 1.00 16.46  ? 73  GLY B N     1 
ATOM   2017 C CA    . GLY D 3 73  ? -77.051  46.543 92.077 1.00 12.12  ? 73  GLY B CA    1 
ATOM   2018 C C     . GLY D 3 73  ? -75.583  46.198 92.191 1.00 19.57  ? 73  GLY B C     1 
ATOM   2019 O O     . GLY D 3 73  ? -74.715  47.030 91.920 1.00 23.14  ? 73  GLY B O     1 
ATOM   2020 N N     . GLY D 3 74  ? -75.306  44.961 92.583 1.00 14.69  ? 74  GLY B N     1 
ATOM   2021 C CA    . GLY D 3 74  ? -73.935  44.537 92.748 1.00 7.30   ? 74  GLY B CA    1 
ATOM   2022 C C     . GLY D 3 74  ? -73.318  43.899 91.525 1.00 20.86  ? 74  GLY B C     1 
ATOM   2023 O O     . GLY D 3 74  ? -73.998  43.608 90.539 1.00 22.45  ? 74  GLY B O     1 
ATOM   2024 N N     . VAL D 3 75  ? -72.009  43.689 91.605 1.00 16.99  ? 75  VAL B N     1 
ATOM   2025 C CA    . VAL D 3 75  ? -71.242  43.079 90.535 1.00 19.51  ? 75  VAL B CA    1 
ATOM   2026 C C     . VAL D 3 75  ? -71.148  41.594 90.862 1.00 19.86  ? 75  VAL B C     1 
ATOM   2027 O O     . VAL D 3 75  ? -70.405  41.196 91.750 1.00 20.06  ? 75  VAL B O     1 
ATOM   2028 C CB    . VAL D 3 75  ? -69.820  43.694 90.462 1.00 13.90  ? 75  VAL B CB    1 
ATOM   2029 C CG1   . VAL D 3 75  ? -68.964  42.951 89.436 1.00 7.68   ? 75  VAL B CG1   1 
ATOM   2030 C CG2   . VAL D 3 75  ? -69.919  45.166 90.104 1.00 12.13  ? 75  VAL B CG2   1 
ATOM   2031 N N     . GLU D 3 76  ? -71.915  40.782 90.146 1.00 25.60  ? 76  GLU B N     1 
ATOM   2032 C CA    . GLU D 3 76  ? -71.917  39.345 90.372 1.00 22.00  ? 76  GLU B CA    1 
ATOM   2033 C C     . GLU D 3 76  ? -71.215  38.603 89.246 1.00 19.75  ? 76  GLU B C     1 
ATOM   2034 O O     . GLU D 3 76  ? -71.632  38.659 88.097 1.00 31.23  ? 76  GLU B O     1 
ATOM   2035 C CB    . GLU D 3 76  ? -73.354  38.845 90.510 1.00 11.86  ? 76  GLU B CB    1 
ATOM   2036 C CG    . GLU D 3 76  ? -74.039  39.352 91.768 1.00 24.59  ? 76  GLU B CG    1 
ATOM   2037 C CD    . GLU D 3 76  ? -75.548  39.283 91.693 1.00 27.44  ? 76  GLU B CD    1 
ATOM   2038 O OE1   . GLU D 3 76  ? -76.089  39.224 90.567 1.00 36.27  ? 76  GLU B OE1   1 
ATOM   2039 O OE2   . GLU D 3 76  ? -76.192  39.288 92.764 1.00 28.49  ? 76  GLU B OE2   1 
ATOM   2040 N N     . LEU D 3 77  ? -70.143  37.908 89.587 1.00 20.14  ? 77  LEU B N     1 
ATOM   2041 C CA    . LEU D 3 77  ? -69.382  37.152 88.608 1.00 15.20  ? 77  LEU B CA    1 
ATOM   2042 C C     . LEU D 3 77  ? -69.220  35.730 89.126 1.00 18.25  ? 77  LEU B C     1 
ATOM   2043 O O     . LEU D 3 77  ? -69.144  35.501 90.332 1.00 33.41  ? 77  LEU B O     1 
ATOM   2044 C CB    . LEU D 3 77  ? -67.997  37.774 88.428 1.00 10.72  ? 77  LEU B CB    1 
ATOM   2045 C CG    . LEU D 3 77  ? -67.670  38.875 87.411 1.00 12.98  ? 77  LEU B CG    1 
ATOM   2046 C CD1   . LEU D 3 77  ? -68.831  39.194 86.469 1.00 12.09  ? 77  LEU B CD1   1 
ATOM   2047 C CD2   . LEU D 3 77  ? -67.262  40.091 88.200 1.00 9.98   ? 77  LEU B CD2   1 
ATOM   2048 N N     . PRO D 3 78  ? -69.177  34.750 88.225 1.00 18.74  ? 78  PRO B N     1 
ATOM   2049 C CA    . PRO D 3 78  ? -69.275  34.889 86.776 1.00 16.64  ? 78  PRO B CA    1 
ATOM   2050 C C     . PRO D 3 78  ? -70.721  34.985 86.319 1.00 20.52  ? 78  PRO B C     1 
ATOM   2051 O O     . PRO D 3 78  ? -71.606  34.324 86.864 1.00 24.93  ? 78  PRO B O     1 
ATOM   2052 C CB    . PRO D 3 78  ? -68.613  33.626 86.261 1.00 16.53  ? 78  PRO B CB    1 
ATOM   2053 C CG    . PRO D 3 78  ? -68.916  32.616 87.307 1.00 14.55  ? 78  PRO B CG    1 
ATOM   2054 C CD    . PRO D 3 78  ? -68.973  33.346 88.623 1.00 26.09  ? 78  PRO B CD    1 
ATOM   2055 N N     . VAL D 3 79  ? -70.933  35.805 85.299 1.00 24.22  ? 79  VAL B N     1 
ATOM   2056 C CA    . VAL D 3 79  ? -72.247  36.043 84.714 1.00 18.64  ? 79  VAL B CA    1 
ATOM   2057 C C     . VAL D 3 79  ? -73.050  34.772 84.469 1.00 17.23  ? 79  VAL B C     1 
ATOM   2058 O O     . VAL D 3 79  ? -74.254  34.714 84.722 1.00 28.78  ? 79  VAL B O     1 
ATOM   2059 C CB    . VAL D 3 79  ? -72.094  36.797 83.377 1.00 17.48  ? 79  VAL B CB    1 
ATOM   2060 C CG1   . VAL D 3 79  ? -73.393  36.753 82.593 1.00 21.44  ? 79  VAL B CG1   1 
ATOM   2061 C CG2   . VAL D 3 79  ? -71.662  38.232 83.646 1.00 7.36   ? 79  VAL B CG2   1 
ATOM   2062 N N     . ALA D 3 80  ? -72.373  33.753 83.968 1.00 24.40  ? 80  ALA B N     1 
ATOM   2063 C CA    . ALA D 3 80  ? -73.020  32.489 83.666 1.00 19.10  ? 80  ALA B CA    1 
ATOM   2064 C C     . ALA D 3 80  ? -73.664  31.815 84.873 1.00 17.49  ? 80  ALA B C     1 
ATOM   2065 O O     . ALA D 3 80  ? -74.549  30.981 84.716 1.00 35.93  ? 80  ALA B O     1 
ATOM   2066 C CB    . ALA D 3 80  ? -72.011  31.553 83.041 1.00 28.60  ? 80  ALA B CB    1 
ATOM   2067 N N     . ALA D 3 81  ? -73.219  32.163 86.075 1.00 16.75  ? 81  ALA B N     1 
ATOM   2068 C CA    . ALA D 3 81  ? -73.753  31.539 87.282 1.00 12.38  ? 81  ALA B CA    1 
ATOM   2069 C C     . ALA D 3 81  ? -74.999  32.234 87.761 1.00 9.59   ? 81  ALA B C     1 
ATOM   2070 O O     . ALA D 3 81  ? -75.778  31.679 88.528 1.00 20.53  ? 81  ALA B O     1 
ATOM   2071 C CB    . ALA D 3 81  ? -72.706  31.561 88.391 1.00 3.34   ? 81  ALA B CB    1 
ATOM   2072 N N     . TRP D 3 82  ? -75.193  33.451 87.284 1.00 14.60  ? 82  TRP B N     1 
ATOM   2073 C CA    . TRP D 3 82  ? -76.313  34.256 87.718 1.00 6.37   ? 82  TRP B CA    1 
ATOM   2074 C C     . TRP D 3 82  ? -77.405  34.473 86.704 1.00 10.51  ? 82  TRP B C     1 
ATOM   2075 O O     . TRP D 3 82  ? -78.291  35.292 86.928 1.00 14.06  ? 82  TRP B O     1 
ATOM   2076 C CB    . TRP D 3 82  ? -75.779  35.605 88.171 1.00 14.32  ? 82  TRP B CB    1 
ATOM   2077 C CG    . TRP D 3 82  ? -75.009  35.506 89.419 1.00 15.78  ? 82  TRP B CG    1 
ATOM   2078 C CD1   . TRP D 3 82  ? -73.655  35.378 89.549 1.00 12.67  ? 82  TRP B CD1   1 
ATOM   2079 C CD2   . TRP D 3 82  ? -75.549  35.490 90.738 1.00 20.84  ? 82  TRP B CD2   1 
ATOM   2080 N NE1   . TRP D 3 82  ? -73.319  35.282 90.881 1.00 22.62  ? 82  TRP B NE1   1 
ATOM   2081 C CE2   . TRP D 3 82  ? -74.466  35.348 91.631 1.00 8.63   ? 82  TRP B CE2   1 
ATOM   2082 C CE3   . TRP D 3 82  ? -76.849  35.582 91.256 1.00 19.87  ? 82  TRP B CE3   1 
ATOM   2083 C CZ2   . TRP D 3 82  ? -74.643  35.297 93.015 1.00 19.48  ? 82  TRP B CZ2   1 
ATOM   2084 C CZ3   . TRP D 3 82  ? -77.026  35.531 92.632 1.00 18.59  ? 82  TRP B CZ3   1 
ATOM   2085 C CH2   . TRP D 3 82  ? -75.928  35.391 93.496 1.00 12.80  ? 82  TRP B CH2   1 
ATOM   2086 N N     . ARG D 3 83  ? -77.370  33.747 85.594 1.00 22.09  ? 83  ARG B N     1 
ATOM   2087 C CA    . ARG D 3 83  ? -78.395  33.963 84.587 1.00 18.40  ? 83  ARG B CA    1 
ATOM   2088 C C     . ARG D 3 83  ? -78.876  32.747 83.845 1.00 13.51  ? 83  ARG B C     1 
ATOM   2089 O O     . ARG D 3 83  ? -78.107  31.836 83.573 1.00 30.72  ? 83  ARG B O     1 
ATOM   2090 C CB    . ARG D 3 83  ? -77.895  34.995 83.594 1.00 12.76  ? 83  ARG B CB    1 
ATOM   2091 C CG    . ARG D 3 83  ? -77.806  36.359 84.223 1.00 16.64  ? 83  ARG B CG    1 
ATOM   2092 C CD    . ARG D 3 83  ? -77.497  37.380 83.194 1.00 36.42  ? 83  ARG B CD    1 
ATOM   2093 N NE    . ARG D 3 83  ? -78.680  37.950 82.544 1.00 27.50  ? 83  ARG B NE    1 
ATOM   2094 C CZ    . ARG D 3 83  ? -79.632  38.638 83.164 1.00 15.43  ? 83  ARG B CZ    1 
ATOM   2095 N NH1   . ARG D 3 83  ? -79.568  38.850 84.472 1.00 13.11  ? 83  ARG B NH1   1 
ATOM   2096 N NH2   . ARG D 3 83  ? -80.615  39.177 82.452 1.00 22.12  ? 83  ARG B NH2   1 
ATOM   2097 N N     . SER D 3 84  ? -80.167  32.743 83.529 1.00 17.27  ? 84  SER B N     1 
ATOM   2098 C CA    . SER D 3 84  ? -80.779  31.654 82.779 1.00 12.91  ? 84  SER B CA    1 
ATOM   2099 C C     . SER D 3 84  ? -81.183  32.194 81.408 1.00 10.97  ? 84  SER B C     1 
ATOM   2100 O O     . SER D 3 84  ? -81.661  33.324 81.286 1.00 11.97  ? 84  SER B O     1 
ATOM   2101 C CB    . SER D 3 84  ? -81.995  31.113 83.523 1.00 11.23  ? 84  SER B CB    1 
ATOM   2102 O OG    . SER D 3 84  ? -81.580  30.286 84.598 1.00 23.71  ? 84  SER B OG    1 
ATOM   2103 N N     . TYR D 3 85  ? -80.980  31.392 80.371 1.00 18.69  ? 85  TYR B N     1 
ATOM   2104 C CA    . TYR D 3 85  ? -81.305  31.833 79.024 1.00 9.08   ? 85  TYR B CA    1 
ATOM   2105 C C     . TYR D 3 85  ? -82.307  30.946 78.324 1.00 11.46  ? 85  TYR B C     1 
ATOM   2106 O O     . TYR D 3 85  ? -82.128  29.729 78.243 1.00 17.60  ? 85  TYR B O     1 
ATOM   2107 C CB    . TYR D 3 85  ? -80.035  31.904 78.187 1.00 4.49   ? 85  TYR B CB    1 
ATOM   2108 C CG    . TYR D 3 85  ? -78.954  32.754 78.808 1.00 12.07  ? 85  TYR B CG    1 
ATOM   2109 C CD1   . TYR D 3 85  ? -78.074  32.216 79.740 1.00 15.82  ? 85  TYR B CD1   1 
ATOM   2110 C CD2   . TYR D 3 85  ? -78.801  34.095 78.453 1.00 11.22  ? 85  TYR B CD2   1 
ATOM   2111 C CE1   . TYR D 3 85  ? -77.063  32.985 80.302 1.00 26.16  ? 85  TYR B CE1   1 
ATOM   2112 C CE2   . TYR D 3 85  ? -77.792  34.877 79.010 1.00 16.72  ? 85  TYR B CE2   1 
ATOM   2113 C CZ    . TYR D 3 85  ? -76.923  34.312 79.934 1.00 23.00  ? 85  TYR B CZ    1 
ATOM   2114 O OH    . TYR D 3 85  ? -75.899  35.058 80.474 1.00 30.85  ? 85  TYR B OH    1 
ATOM   2115 N N     . LEU D 3 86  ? -83.369  31.569 77.827 1.00 11.43  ? 86  LEU B N     1 
ATOM   2116 C CA    . LEU D 3 86  ? -84.401  30.852 77.103 1.00 18.47  ? 86  LEU B CA    1 
ATOM   2117 C C     . LEU D 3 86  ? -84.340  31.313 75.663 1.00 16.48  ? 86  LEU B C     1 
ATOM   2118 O O     . LEU D 3 86  ? -84.375  32.511 75.383 1.00 18.59  ? 86  LEU B O     1 
ATOM   2119 C CB    . LEU D 3 86  ? -85.796  31.151 77.662 1.00 15.16  ? 86  LEU B CB    1 
ATOM   2120 C CG    . LEU D 3 86  ? -86.919  30.633 76.752 1.00 19.97  ? 86  LEU B CG    1 
ATOM   2121 C CD1   . LEU D 3 86  ? -86.795  29.126 76.612 1.00 24.21  ? 86  LEU B CD1   1 
ATOM   2122 C CD2   . LEU D 3 86  ? -88.274  30.990 77.323 1.00 24.31  ? 86  LEU B CD2   1 
ATOM   2123 N N     . ASN D 3 87  ? -84.236  30.352 74.756 1.00 22.60  ? 87  ASN B N     1 
ATOM   2124 C CA    . ASN D 3 87  ? -84.185  30.643 73.335 1.00 19.34  ? 87  ASN B CA    1 
ATOM   2125 C C     . ASN D 3 87  ? -85.335  29.892 72.668 1.00 16.88  ? 87  ASN B C     1 
ATOM   2126 O O     . ASN D 3 87  ? -85.411  28.670 72.744 1.00 24.60  ? 87  ASN B O     1 
ATOM   2127 C CB    . ASN D 3 87  ? -82.838  30.194 72.769 1.00 21.57  ? 87  ASN B CB    1 
ATOM   2128 C CG    A ASN D 3 87  ? -81.669  31.023 73.304 0.55 27.47  ? 87  ASN B CG    1 
ATOM   2129 C CG    B ASN D 3 87  ? -82.567  30.768 71.399 0.45 34.06  ? 87  ASN B CG    1 
ATOM   2130 O OD1   A ASN D 3 87  ? -81.719  32.250 73.316 0.55 29.99  ? 87  ASN B OD1   1 
ATOM   2131 O OD1   B ASN D 3 87  ? -83.327  31.597 70.902 0.45 40.26  ? 87  ASN B OD1   1 
ATOM   2132 N ND2   A ASN D 3 87  ? -80.611  30.348 73.744 0.55 35.42  ? 87  ASN B ND2   1 
ATOM   2133 N ND2   B ASN D 3 87  ? -81.479  30.330 70.777 0.45 47.30  ? 87  ASN B ND2   1 
ATOM   2134 N N     . MET D 3 88  ? -86.243  30.628 72.036 1.00 19.06  ? 88  MET B N     1 
ATOM   2135 C CA    . MET D 3 88  ? -87.396  30.025 71.366 1.00 16.10  ? 88  MET B CA    1 
ATOM   2136 C C     . MET D 3 88  ? -87.429  30.372 69.896 1.00 16.05  ? 88  MET B C     1 
ATOM   2137 O O     . MET D 3 88  ? -87.314  31.536 69.524 1.00 26.53  ? 88  MET B O     1 
ATOM   2138 C CB    . MET D 3 88  ? -88.700  30.528 71.966 1.00 9.15   ? 88  MET B CB    1 
ATOM   2139 C CG    . MET D 3 88  ? -89.094  29.881 73.257 1.00 34.01  ? 88  MET B CG    1 
ATOM   2140 S SD    . MET D 3 88  ? -90.633  30.599 73.804 1.00 42.05  ? 88  MET B SD    1 
ATOM   2141 C CE    . MET D 3 88  ? -91.485  30.777 72.276 1.00 16.73  ? 88  MET B CE    1 
ATOM   2142 N N     . GLU D 3 89  ? -87.589  29.362 69.055 1.00 20.62  ? 89  GLU B N     1 
ATOM   2143 C CA    . GLU D 3 89  ? -87.687  29.596 67.629 1.00 10.28  ? 89  GLU B CA    1 
ATOM   2144 C C     . GLU D 3 89  ? -88.973  28.914 67.168 1.00 19.77  ? 89  GLU B C     1 
ATOM   2145 O O     . GLU D 3 89  ? -89.145  27.700 67.313 1.00 20.06  ? 89  GLU B O     1 
ATOM   2146 C CB    . GLU D 3 89  ? -86.471  29.033 66.903 1.00 23.48  ? 89  GLU B CB    1 
ATOM   2147 C CG    . GLU D 3 89  ? -85.973  29.945 65.792 1.00 58.39  ? 89  GLU B CG    1 
ATOM   2148 C CD    . GLU D 3 89  ? -84.503  29.760 65.491 1.00 70.15  ? 89  GLU B CD    1 
ATOM   2149 O OE1   . GLU D 3 89  ? -84.122  28.638 65.099 1.00 74.67  ? 89  GLU B OE1   1 
ATOM   2150 O OE2   . GLU D 3 89  ? -83.735  30.738 65.645 1.00 79.57  ? 89  GLU B OE2   1 
ATOM   2151 N N     . LEU D 3 90  ? -89.889  29.721 66.647 1.00 15.72  ? 90  LEU B N     1 
ATOM   2152 C CA    . LEU D 3 90  ? -91.176  29.239 66.177 1.00 17.40  ? 90  LEU B CA    1 
ATOM   2153 C C     . LEU D 3 90  ? -91.241  29.359 64.659 1.00 17.47  ? 90  LEU B C     1 
ATOM   2154 O O     . LEU D 3 90  ? -91.155  30.458 64.105 1.00 17.64  ? 90  LEU B O     1 
ATOM   2155 C CB    . LEU D 3 90  ? -92.297  30.059 66.829 1.00 16.59  ? 90  LEU B CB    1 
ATOM   2156 C CG    . LEU D 3 90  ? -93.753  29.738 66.487 1.00 26.67  ? 90  LEU B CG    1 
ATOM   2157 C CD1   . LEU D 3 90  ? -94.013  28.248 66.649 1.00 31.83  ? 90  LEU B CD1   1 
ATOM   2158 C CD2   . LEU D 3 90  ? -94.670  30.547 67.396 1.00 25.72  ? 90  LEU B CD2   1 
ATOM   2159 N N     . THR D 3 91  ? -91.372  28.218 63.993 1.00 19.05  ? 91  THR B N     1 
ATOM   2160 C CA    . THR D 3 91  ? -91.450  28.173 62.539 1.00 17.60  ? 91  THR B CA    1 
ATOM   2161 C C     . THR D 3 91  ? -92.894  27.956 62.134 1.00 19.07  ? 91  THR B C     1 
ATOM   2162 O O     . THR D 3 91  ? -93.532  27.000 62.569 1.00 29.44  ? 91  THR B O     1 
ATOM   2163 C CB    . THR D 3 91  ? -90.618  27.025 61.982 1.00 13.78  ? 91  THR B CB    1 
ATOM   2164 O OG1   . THR D 3 91  ? -89.267  27.167 62.425 1.00 23.06  ? 91  THR B OG1   1 
ATOM   2165 C CG2   . THR D 3 91  ? -90.661  27.024 60.467 1.00 19.54  ? 91  THR B CG2   1 
ATOM   2166 N N     . ILE D 3 92  ? -93.404  28.844 61.294 1.00 20.32  ? 92  ILE B N     1 
ATOM   2167 C CA    . ILE D 3 92  ? -94.784  28.757 60.849 1.00 12.27  ? 92  ILE B CA    1 
ATOM   2168 C C     . ILE D 3 92  ? -94.867  28.845 59.334 1.00 23.17  ? 92  ILE B C     1 
ATOM   2169 O O     . ILE D 3 92  ? -94.425  29.825 58.740 1.00 30.26  ? 92  ILE B O     1 
ATOM   2170 C CB    . ILE D 3 92  ? -95.620  29.903 61.450 1.00 12.79  ? 92  ILE B CB    1 
ATOM   2171 C CG1   . ILE D 3 92  ? -95.379  29.981 62.961 1.00 8.12   ? 92  ILE B CG1   1 
ATOM   2172 C CG2   . ILE D 3 92  ? -97.095  29.703 61.137 1.00 14.62  ? 92  ILE B CG2   1 
ATOM   2173 C CD1   . ILE D 3 92  ? -95.971  31.211 63.606 1.00 16.47  ? 92  ILE B CD1   1 
ATOM   2174 N N     . PRO D 3 93  ? -95.419  27.807 58.688 1.00 21.15  ? 93  PRO B N     1 
ATOM   2175 C CA    . PRO D 3 93  ? -95.572  27.756 57.230 1.00 15.56  ? 93  PRO B CA    1 
ATOM   2176 C C     . PRO D 3 93  ? -96.400  28.952 56.766 1.00 19.20  ? 93  PRO B C     1 
ATOM   2177 O O     . PRO D 3 93  ? -97.340  29.349 57.451 1.00 23.65  ? 93  PRO B O     1 
ATOM   2178 C CB    . PRO D 3 93  ? -96.298  26.436 56.993 1.00 14.15  ? 93  PRO B CB    1 
ATOM   2179 C CG    . PRO D 3 93  ? -96.000  25.621 58.198 1.00 13.01  ? 93  PRO B CG    1 
ATOM   2180 C CD    . PRO D 3 93  ? -95.924  26.586 59.334 1.00 22.35  ? 93  PRO B CD    1 
ATOM   2181 N N     . ILE D 3 94  ? -96.066  29.516 55.607 1.00 21.11  ? 94  ILE B N     1 
ATOM   2182 C CA    . ILE D 3 94  ? -96.780  30.690 55.104 1.00 17.27  ? 94  ILE B CA    1 
ATOM   2183 C C     . ILE D 3 94  ? -98.264  30.485 54.846 1.00 24.26  ? 94  ILE B C     1 
ATOM   2184 O O     . ILE D 3 94  ? -98.982  31.446 54.560 1.00 23.08  ? 94  ILE B O     1 
ATOM   2185 C CB    . ILE D 3 94  ? -96.165  31.217 53.801 1.00 21.54  ? 94  ILE B CB    1 
ATOM   2186 C CG1   . ILE D 3 94  ? -96.016  30.075 52.804 1.00 28.01  ? 94  ILE B CG1   1 
ATOM   2187 C CG2   . ILE D 3 94  ? -94.832  31.866 54.079 1.00 16.21  ? 94  ILE B CG2   1 
ATOM   2188 C CD1   . ILE D 3 94  ? -96.102  30.531 51.380 1.00 18.18  ? 94  ILE B CD1   1 
ATOM   2189 N N     . PHE D 3 95  ? -98.733  29.246 54.948 1.00 20.33  ? 95  PHE B N     1 
ATOM   2190 C CA    . PHE D 3 95  ? -100.144 28.965 54.708 1.00 21.96  ? 95  PHE B CA    1 
ATOM   2191 C C     . PHE D 3 95  ? -100.999 29.143 55.947 1.00 25.83  ? 95  PHE B C     1 
ATOM   2192 O O     . PHE D 3 95  ? -102.228 29.174 55.864 1.00 32.42  ? 95  PHE B O     1 
ATOM   2193 C CB    . PHE D 3 95  ? -100.306 27.547 54.174 1.00 7.66   ? 95  PHE B CB    1 
ATOM   2194 C CG    . PHE D 3 95  ? -99.444  27.263 52.991 1.00 18.80  ? 95  PHE B CG    1 
ATOM   2195 C CD1   . PHE D 3 95  ? -99.712  27.862 51.767 1.00 23.64  ? 95  PHE B CD1   1 
ATOM   2196 C CD2   . PHE D 3 95  ? -98.328  26.450 53.109 1.00 22.12  ? 95  PHE B CD2   1 
ATOM   2197 C CE1   . PHE D 3 95  ? -98.878  27.660 50.680 1.00 26.74  ? 95  PHE B CE1   1 
ATOM   2198 C CE2   . PHE D 3 95  ? -97.484  26.240 52.025 1.00 13.97  ? 95  PHE B CE2   1 
ATOM   2199 C CZ    . PHE D 3 95  ? -97.759  26.848 50.809 1.00 18.16  ? 95  PHE B CZ    1 
ATOM   2200 N N     . ALA D 3 96  ? -100.344 29.272 57.094 1.00 23.86  ? 96  ALA B N     1 
ATOM   2201 C CA    . ALA D 3 96  ? -101.046 29.426 58.359 1.00 18.30  ? 96  ALA B CA    1 
ATOM   2202 C C     . ALA D 3 96  ? -101.902 30.675 58.391 1.00 21.26  ? 96  ALA B C     1 
ATOM   2203 O O     . ALA D 3 96  ? -101.421 31.779 58.168 1.00 26.19  ? 96  ALA B O     1 
ATOM   2204 C CB    . ALA D 3 96  ? -100.052 29.460 59.503 1.00 13.64  ? 96  ALA B CB    1 
ATOM   2205 N N     . THR D 3 97  ? -103.182 30.491 58.664 1.00 22.41  ? 97  THR B N     1 
ATOM   2206 C CA    . THR D 3 97  ? -104.096 31.613 58.758 1.00 17.76  ? 97  THR B CA    1 
ATOM   2207 C C     . THR D 3 97  ? -103.973 32.160 60.174 1.00 21.53  ? 97  THR B C     1 
ATOM   2208 O O     . THR D 3 97  ? -103.194 31.648 60.980 1.00 26.47  ? 97  THR B O     1 
ATOM   2209 C CB    . THR D 3 97  ? -105.537 31.157 58.527 1.00 16.07  ? 97  THR B CB    1 
ATOM   2210 O OG1   . THR D 3 97  ? -105.873 30.127 59.466 1.00 25.79  ? 97  THR B OG1   1 
ATOM   2211 C CG2   . THR D 3 97  ? -105.685 30.612 57.131 1.00 14.86  ? 97  THR B CG2   1 
ATOM   2212 N N     . ASN D 3 98  ? -104.738 33.197 60.483 1.00 24.64  ? 98  ASN B N     1 
ATOM   2213 C CA    . ASN D 3 98  ? -104.691 33.765 61.819 1.00 20.83  ? 98  ASN B CA    1 
ATOM   2214 C C     . ASN D 3 98  ? -105.214 32.739 62.830 1.00 28.47  ? 98  ASN B C     1 
ATOM   2215 O O     . ASN D 3 98  ? -104.658 32.596 63.923 1.00 39.63  ? 98  ASN B O     1 
ATOM   2216 C CB    . ASN D 3 98  ? -105.523 35.047 61.875 1.00 16.00  ? 98  ASN B CB    1 
ATOM   2217 C CG    . ASN D 3 98  ? -104.786 36.247 61.314 1.00 23.83  ? 98  ASN B CG    1 
ATOM   2218 O OD1   . ASN D 3 98  ? -103.635 36.147 60.891 1.00 33.83  ? 98  ASN B OD1   1 
ATOM   2219 N ND2   . ASN D 3 98  ? -105.447 37.393 61.312 1.00 19.69  ? 98  ASN B ND2   1 
ATOM   2220 N N     . SER D 3 99  ? -106.281 32.029 62.461 1.00 25.04  ? 99  SER B N     1 
ATOM   2221 C CA    . SER D 3 99  ? -106.834 31.012 63.346 1.00 26.87  ? 99  SER B CA    1 
ATOM   2222 C C     . SER D 3 99  ? -105.834 29.886 63.581 1.00 24.98  ? 99  SER B C     1 
ATOM   2223 O O     . SER D 3 99  ? -105.668 29.412 64.693 1.00 31.71  ? 99  SER B O     1 
ATOM   2224 C CB    . SER D 3 99  ? -108.140 30.458 62.776 1.00 15.18  ? 99  SER B CB    1 
ATOM   2225 O OG    . SER D 3 99  ? -109.133 31.467 62.698 1.00 73.91  ? 99  SER B OG    1 
ATOM   2226 N N     . ASP D 3 100 ? -105.148 29.490 62.509 1.00 18.72  ? 100 ASP B N     1 
ATOM   2227 C CA    . ASP D 3 100 ? -104.123 28.463 62.643 1.00 16.58  ? 100 ASP B CA    1 
ATOM   2228 C C     . ASP D 3 100 ? -103.130 28.951 63.707 1.00 23.60  ? 100 ASP B C     1 
ATOM   2229 O O     . ASP D 3 100 ? -102.762 28.214 64.626 1.00 24.49  ? 100 ASP B O     1 
ATOM   2230 C CB    . ASP D 3 100 ? -103.382 28.264 61.319 1.00 14.80  ? 100 ASP B CB    1 
ATOM   2231 C CG    . ASP D 3 100 ? -104.203 27.507 60.285 1.00 27.52  ? 100 ASP B CG    1 
ATOM   2232 O OD1   . ASP D 3 100 ? -105.095 26.713 60.666 1.00 22.59  ? 100 ASP B OD1   1 
ATOM   2233 O OD2   . ASP D 3 100 ? -103.942 27.711 59.081 1.00 31.57  ? 100 ASP B OD2   1 
ATOM   2234 N N     . CYS D 3 101 ? -102.713 30.209 63.582 1.00 16.45  ? 101 CYS B N     1 
ATOM   2235 C CA    . CYS D 3 101 ? -101.763 30.802 64.514 1.00 16.76  ? 101 CYS B CA    1 
ATOM   2236 C C     . CYS D 3 101 ? -102.273 30.917 65.938 1.00 22.27  ? 101 CYS B C     1 
ATOM   2237 O O     . CYS D 3 101 ? -101.494 30.833 66.889 1.00 23.37  ? 101 CYS B O     1 
ATOM   2238 C CB    . CYS D 3 101 ? -101.336 32.166 64.010 1.00 12.95  ? 101 CYS B CB    1 
ATOM   2239 S SG    . CYS D 3 101 ? -100.285 32.006 62.570 1.00 22.94  ? 101 CYS B SG    1 
ATOM   2240 N N     . GLU D 3 102 ? -103.573 31.129 66.093 1.00 16.50  ? 102 GLU B N     1 
ATOM   2241 C CA    . GLU D 3 102 ? -104.143 31.210 67.428 1.00 25.28  ? 102 GLU B CA    1 
ATOM   2242 C C     . GLU D 3 102 ? -103.956 29.840 68.078 1.00 27.87  ? 102 GLU B C     1 
ATOM   2243 O O     . GLU D 3 102 ? -103.560 29.733 69.242 1.00 24.41  ? 102 GLU B O     1 
ATOM   2244 C CB    . GLU D 3 102 ? -105.628 31.535 67.354 1.00 27.70  ? 102 GLU B CB    1 
ATOM   2245 C CG    . GLU D 3 102 ? -105.935 33.006 67.389 1.00 46.10  ? 102 GLU B CG    1 
ATOM   2246 C CD    . GLU D 3 102 ? -107.332 33.296 66.907 1.00 55.06  ? 102 GLU B CD    1 
ATOM   2247 O OE1   . GLU D 3 102 ? -108.271 32.637 67.408 1.00 64.49  ? 102 GLU B OE1   1 
ATOM   2248 O OE2   . GLU D 3 102 ? -107.488 34.174 66.030 1.00 57.27  ? 102 GLU B OE2   1 
ATOM   2249 N N     . LEU D 3 103 ? -104.240 28.792 67.311 1.00 13.78  ? 103 LEU B N     1 
ATOM   2250 C CA    . LEU D 3 103 ? -104.092 27.437 67.811 1.00 16.31  ? 103 LEU B CA    1 
ATOM   2251 C C     . LEU D 3 103 ? -102.662 27.182 68.267 1.00 19.34  ? 103 LEU B C     1 
ATOM   2252 O O     . LEU D 3 103 ? -102.436 26.606 69.330 1.00 21.72  ? 103 LEU B O     1 
ATOM   2253 C CB    . LEU D 3 103 ? -104.464 26.431 66.730 1.00 11.93  ? 103 LEU B CB    1 
ATOM   2254 C CG    . LEU D 3 103 ? -104.720 25.037 67.294 1.00 23.63  ? 103 LEU B CG    1 
ATOM   2255 C CD1   . LEU D 3 103 ? -106.183 24.679 67.106 1.00 34.84  ? 103 LEU B CD1   1 
ATOM   2256 C CD2   . LEU D 3 103 ? -103.812 24.035 66.609 1.00 29.83  ? 103 LEU B CD2   1 
ATOM   2257 N N     . ILE D 3 104 ? -101.699 27.606 67.454 1.00 14.95  ? 104 ILE B N     1 
ATOM   2258 C CA    . ILE D 3 104 ? -100.292 27.427 67.785 1.00 16.64  ? 104 ILE B CA    1 
ATOM   2259 C C     . ILE D 3 104 ? -99.985  28.098 69.122 1.00 17.14  ? 104 ILE B C     1 
ATOM   2260 O O     . ILE D 3 104 ? -99.331  27.519 69.992 1.00 21.00  ? 104 ILE B O     1 
ATOM   2261 C CB    . ILE D 3 104 ? -99.389  28.028 66.689 1.00 18.63  ? 104 ILE B CB    1 
ATOM   2262 C CG1   . ILE D 3 104 ? -99.323  27.073 65.495 1.00 18.03  ? 104 ILE B CG1   1 
ATOM   2263 C CG2   . ILE D 3 104 ? -97.990  28.275 67.233 1.00 7.24   ? 104 ILE B CG2   1 
ATOM   2264 C CD1   . ILE D 3 104 ? -98.995  27.753 64.182 1.00 22.02  ? 104 ILE B CD1   1 
ATOM   2265 N N     . VAL D 3 105 ? -100.461 29.322 69.289 1.00 8.33   ? 105 VAL B N     1 
ATOM   2266 C CA    . VAL D 3 105 ? -100.234 30.032 70.536 1.00 14.69  ? 105 VAL B CA    1 
ATOM   2267 C C     . VAL D 3 105 ? -100.841 29.262 71.710 1.00 18.43  ? 105 VAL B C     1 
ATOM   2268 O O     . VAL D 3 105 ? -100.216 29.124 72.759 1.00 14.38  ? 105 VAL B O     1 
ATOM   2269 C CB    . VAL D 3 105 ? -100.838 31.435 70.476 1.00 14.46  ? 105 VAL B CB    1 
ATOM   2270 C CG1   . VAL D 3 105 ? -100.880 32.051 71.870 1.00 8.92   ? 105 VAL B CG1   1 
ATOM   2271 C CG2   . VAL D 3 105 ? -100.017 32.292 69.522 1.00 12.25  ? 105 VAL B CG2   1 
ATOM   2272 N N     . LYS D 3 106 ? -102.058 28.756 71.525 1.00 18.95  ? 106 LYS B N     1 
ATOM   2273 C CA    . LYS D 3 106 ? -102.737 27.991 72.566 1.00 12.54  ? 106 LYS B CA    1 
ATOM   2274 C C     . LYS D 3 106 ? -101.882 26.798 72.982 1.00 20.80  ? 106 LYS B C     1 
ATOM   2275 O O     . LYS D 3 106 ? -101.710 26.526 74.171 1.00 20.23  ? 106 LYS B O     1 
ATOM   2276 C CB    . LYS D 3 106 ? -104.086 27.486 72.057 1.00 12.11  ? 106 LYS B CB    1 
ATOM   2277 C CG    . LYS D 3 106 ? -105.210 28.511 72.138 1.00 25.52  ? 106 LYS B CG    1 
ATOM   2278 C CD    . LYS D 3 106 ? -106.572 27.850 71.951 1.00 41.80  ? 106 LYS B CD    1 
ATOM   2279 C CE    . LYS D 3 106 ? -107.702 28.865 72.038 1.00 60.78  ? 106 LYS B CE    1 
ATOM   2280 N NZ    . LYS D 3 106 ? -107.469 29.863 73.123 1.00 80.50  ? 106 LYS B NZ    1 
ATOM   2281 N N     . ALA D 3 107 ? -101.347 26.090 71.992 1.00 18.76  ? 107 ALA B N     1 
ATOM   2282 C CA    . ALA D 3 107 ? -100.508 24.928 72.251 1.00 19.63  ? 107 ALA B CA    1 
ATOM   2283 C C     . ALA D 3 107 ? -99.312  25.319 73.102 1.00 20.95  ? 107 ALA B C     1 
ATOM   2284 O O     . ALA D 3 107 ? -98.891  24.560 73.975 1.00 26.01  ? 107 ALA B O     1 
ATOM   2285 C CB    . ALA D 3 107 ? -100.035 24.324 70.944 1.00 9.48   ? 107 ALA B CB    1 
ATOM   2286 N N     . MET D 3 108 ? -98.760  26.503 72.848 1.00 17.33  ? 108 MET B N     1 
ATOM   2287 C CA    . MET D 3 108 ? -97.608  26.966 73.613 1.00 16.57  ? 108 MET B CA    1 
ATOM   2288 C C     . MET D 3 108 ? -98.030  27.252 75.043 1.00 19.51  ? 108 MET B C     1 
ATOM   2289 O O     . MET D 3 108 ? -97.323  26.930 75.996 1.00 24.89  ? 108 MET B O     1 
ATOM   2290 C CB    . MET D 3 108 ? -97.027  28.225 72.987 1.00 13.42  ? 108 MET B CB    1 
ATOM   2291 C CG    . MET D 3 108 ? -96.045  27.945 71.871 1.00 14.76  ? 108 MET B CG    1 
ATOM   2292 S SD    . MET D 3 108 ? -95.311  29.475 71.269 1.00 33.01  ? 108 MET B SD    1 
ATOM   2293 C CE    . MET D 3 108 ? -96.685  30.172 70.421 1.00 28.84  ? 108 MET B CE    1 
ATOM   2294 N N     . GLN D 3 109 ? -99.198  27.859 75.187 1.00 17.95  ? 109 GLN B N     1 
ATOM   2295 C CA    . GLN D 3 109 ? -99.728  28.177 76.500 1.00 13.23  ? 109 GLN B CA    1 
ATOM   2296 C C     . GLN D 3 109 ? -99.971  26.895 77.278 1.00 16.18  ? 109 GLN B C     1 
ATOM   2297 O O     . GLN D 3 109 ? -99.649  26.809 78.465 1.00 25.06  ? 109 GLN B O     1 
ATOM   2298 C CB    . GLN D 3 109 ? -101.031 28.949 76.351 1.00 9.34   ? 109 GLN B CB    1 
ATOM   2299 C CG    . GLN D 3 109 ? -100.852 30.231 75.574 1.00 18.48  ? 109 GLN B CG    1 
ATOM   2300 C CD    . GLN D 3 109 ? -102.118 31.025 75.473 1.00 17.93  ? 109 GLN B CD    1 
ATOM   2301 O OE1   . GLN D 3 109 ? -103.212 30.463 75.359 1.00 36.22  ? 109 GLN B OE1   1 
ATOM   2302 N NE2   . GLN D 3 109 ? -101.987 32.347 75.514 1.00 17.00  ? 109 GLN B NE2   1 
ATOM   2303 N N     . GLY D 3 110 ? -100.535 25.901 76.596 1.00 13.45  ? 110 GLY B N     1 
ATOM   2304 C CA    . GLY D 3 110 ? -100.814 24.625 77.229 1.00 15.73  ? 110 GLY B CA    1 
ATOM   2305 C C     . GLY D 3 110 ? -99.549  23.909 77.654 1.00 19.24  ? 110 GLY B C     1 
ATOM   2306 O O     . GLY D 3 110 ? -99.476  23.333 78.739 1.00 17.70  ? 110 GLY B O     1 
ATOM   2307 N N     . LEU D 3 111 ? -98.539  23.948 76.796 1.00 21.84  ? 111 LEU B N     1 
ATOM   2308 C CA    . LEU D 3 111 ? -97.276  23.301 77.100 1.00 18.23  ? 111 LEU B CA    1 
ATOM   2309 C C     . LEU D 3 111 ? -96.738  23.755 78.457 1.00 19.27  ? 111 LEU B C     1 
ATOM   2310 O O     . LEU D 3 111 ? -96.218  22.949 79.223 1.00 26.80  ? 111 LEU B O     1 
ATOM   2311 C CB    . LEU D 3 111 ? -96.263  23.621 76.001 1.00 14.66  ? 111 LEU B CB    1 
ATOM   2312 C CG    . LEU D 3 111 ? -94.830  23.144 76.217 1.00 15.26  ? 111 LEU B CG    1 
ATOM   2313 C CD1   . LEU D 3 111 ? -94.766  21.644 76.041 1.00 18.15  ? 111 LEU B CD1   1 
ATOM   2314 C CD2   . LEU D 3 111 ? -93.912  23.824 75.223 1.00 20.88  ? 111 LEU B CD2   1 
ATOM   2315 N N     . LEU D 3 112 ? -96.888  25.041 78.763 1.00 21.19  ? 112 LEU B N     1 
ATOM   2316 C CA    . LEU D 3 112 ? -96.374  25.595 80.017 1.00 24.22  ? 112 LEU B CA    1 
ATOM   2317 C C     . LEU D 3 112 ? -97.374  25.898 81.130 1.00 28.61  ? 112 LEU B C     1 
ATOM   2318 O O     . LEU D 3 112 ? -97.012  26.525 82.134 1.00 24.68  ? 112 LEU B O     1 
ATOM   2319 C CB    . LEU D 3 112 ? -95.599  26.875 79.731 1.00 6.58   ? 112 LEU B CB    1 
ATOM   2320 C CG    . LEU D 3 112 ? -94.520  26.819 78.663 1.00 23.75  ? 112 LEU B CG    1 
ATOM   2321 C CD1   . LEU D 3 112 ? -94.305  28.218 78.097 1.00 14.95  ? 112 LEU B CD1   1 
ATOM   2322 C CD2   . LEU D 3 112 ? -93.241  26.283 79.273 1.00 14.00  ? 112 LEU B CD2   1 
ATOM   2323 N N     . LYS D 3 113 ? -98.623  25.473 80.970 1.00 24.68  ? 113 LYS B N     1 
ATOM   2324 C CA    . LYS D 3 113 ? -99.624  25.733 82.005 1.00 25.68  ? 113 LYS B CA    1 
ATOM   2325 C C     . LYS D 3 113 ? -99.195  25.141 83.346 1.00 22.80  ? 113 LYS B C     1 
ATOM   2326 O O     . LYS D 3 113 ? -98.605  24.059 83.400 1.00 23.60  ? 113 LYS B O     1 
ATOM   2327 C CB    . LYS D 3 113 ? -100.981 25.150 81.602 1.00 20.96  ? 113 LYS B CB    1 
ATOM   2328 C CG    . LYS D 3 113 ? -102.111 25.466 82.579 1.00 25.33  ? 113 LYS B CG    1 
ATOM   2329 C CD    . LYS D 3 113 ? -103.467 25.067 82.012 1.00 47.25  ? 113 LYS B CD    1 
ATOM   2330 C CE    . LYS D 3 113 ? -104.580 25.238 83.033 1.00 51.34  ? 113 LYS B CE    1 
ATOM   2331 N NZ    . LYS D 3 113 ? -105.697 24.277 82.794 1.00 71.39  ? 113 LYS B NZ    1 
ATOM   2332 N N     . ASP D 3 114 ? -99.487  25.853 84.427 1.00 26.68  ? 114 ASP B N     1 
ATOM   2333 C CA    . ASP D 3 114 ? -99.134  25.373 85.760 1.00 28.45  ? 114 ASP B CA    1 
ATOM   2334 C C     . ASP D 3 114 ? -99.649  23.962 85.985 1.00 24.03  ? 114 ASP B C     1 
ATOM   2335 O O     . ASP D 3 114 ? -100.781 23.638 85.626 1.00 30.71  ? 114 ASP B O     1 
ATOM   2336 C CB    . ASP D 3 114 ? -99.726  26.280 86.825 1.00 29.06  ? 114 ASP B CB    1 
ATOM   2337 C CG    . ASP D 3 114 ? -98.679  26.882 87.705 1.00 48.70  ? 114 ASP B CG    1 
ATOM   2338 O OD1   . ASP D 3 114 ? -97.526  27.031 87.241 1.00 66.47  ? 114 ASP B OD1   1 
ATOM   2339 O OD2   . ASP D 3 114 ? -99.009  27.208 88.862 1.00 81.53  ? 114 ASP B OD2   1 
ATOM   2340 N N     . GLY D 3 115 ? -98.814  23.118 86.579 1.00 27.17  ? 115 GLY B N     1 
ATOM   2341 C CA    . GLY D 3 115 ? -99.231  21.754 86.846 1.00 21.42  ? 115 GLY B CA    1 
ATOM   2342 C C     . GLY D 3 115 ? -98.926  20.742 85.759 1.00 26.96  ? 115 GLY B C     1 
ATOM   2343 O O     . GLY D 3 115 ? -99.056  19.539 85.975 1.00 35.01  ? 115 GLY B O     1 
ATOM   2344 N N     . ASN D 3 116 ? -98.526  21.211 84.585 1.00 27.53  ? 116 ASN B N     1 
ATOM   2345 C CA    . ASN D 3 116 ? -98.215  20.288 83.512 1.00 17.69  ? 116 ASN B CA    1 
ATOM   2346 C C     . ASN D 3 116 ? -96.788  19.779 83.647 1.00 24.57  ? 116 ASN B C     1 
ATOM   2347 O O     . ASN D 3 116 ? -95.949  20.403 84.291 1.00 25.51  ? 116 ASN B O     1 
ATOM   2348 C CB    . ASN D 3 116 ? -98.462  20.958 82.168 1.00 21.18  ? 116 ASN B CB    1 
ATOM   2349 C CG    . ASN D 3 116 ? -99.935  20.996 81.823 1.00 27.96  ? 116 ASN B CG    1 
ATOM   2350 O OD1   . ASN D 3 116 ? -100.731 20.299 82.448 1.00 28.01  ? 116 ASN B OD1   1 
ATOM   2351 N ND2   . ASN D 3 116 ? -100.310 21.807 80.837 1.00 21.15  ? 116 ASN B ND2   1 
ATOM   2352 N N     . PRO D 3 117 ? -96.491  18.636 83.024 1.00 26.96  ? 117 PRO B N     1 
ATOM   2353 C CA    . PRO D 3 117 ? -95.158  18.034 83.093 1.00 23.57  ? 117 PRO B CA    1 
ATOM   2354 C C     . PRO D 3 117 ? -93.937  18.953 82.959 1.00 26.59  ? 117 PRO B C     1 
ATOM   2355 O O     . PRO D 3 117 ? -93.152  19.081 83.897 1.00 23.03  ? 117 PRO B O     1 
ATOM   2356 C CB    . PRO D 3 117 ? -95.200  16.963 82.007 1.00 27.83  ? 117 PRO B CB    1 
ATOM   2357 C CG    . PRO D 3 117 ? -96.639  16.590 81.916 1.00 18.65  ? 117 PRO B CG    1 
ATOM   2358 C CD    . PRO D 3 117 ? -97.401  17.862 82.161 1.00 21.71  ? 117 PRO B CD    1 
ATOM   2359 N N     . ILE D 3 118 ? -93.772  19.587 81.802 1.00 24.79  ? 118 ILE B N     1 
ATOM   2360 C CA    . ILE D 3 118 ? -92.614  20.445 81.573 1.00 19.62  ? 118 ILE B CA    1 
ATOM   2361 C C     . ILE D 3 118 ? -92.378  21.530 82.627 1.00 24.98  ? 118 ILE B C     1 
ATOM   2362 O O     . ILE D 3 118 ? -91.303  21.596 83.229 1.00 24.25  ? 118 ILE B O     1 
ATOM   2363 C CB    . ILE D 3 118 ? -92.680  21.106 80.188 1.00 29.00  ? 118 ILE B CB    1 
ATOM   2364 C CG1   . ILE D 3 118 ? -93.177  20.092 79.149 1.00 21.41  ? 118 ILE B CG1   1 
ATOM   2365 C CG2   . ILE D 3 118 ? -91.311  21.668 79.828 1.00 19.18  ? 118 ILE B CG2   1 
ATOM   2366 C CD1   . ILE D 3 118 ? -92.115  19.180 78.623 1.00 17.82  ? 118 ILE B CD1   1 
ATOM   2367 N N     . PRO D 3 119 ? -93.366  22.407 82.858 1.00 18.17  ? 119 PRO B N     1 
ATOM   2368 C CA    . PRO D 3 119 ? -93.128  23.441 83.869 1.00 17.73  ? 119 PRO B CA    1 
ATOM   2369 C C     . PRO D 3 119 ? -92.836  22.845 85.241 1.00 18.06  ? 119 PRO B C     1 
ATOM   2370 O O     . PRO D 3 119 ? -92.043  23.382 86.016 1.00 30.04  ? 119 PRO B O     1 
ATOM   2371 C CB    . PRO D 3 119 ? -94.415  24.266 83.864 1.00 10.52  ? 119 PRO B CB    1 
ATOM   2372 C CG    . PRO D 3 119 ? -95.425  23.420 83.194 1.00 14.79  ? 119 PRO B CG    1 
ATOM   2373 C CD    . PRO D 3 119 ? -94.690  22.536 82.234 1.00 19.47  ? 119 PRO B CD    1 
ATOM   2374 N N     . SER D 3 120 ? -93.475  21.722 85.529 1.00 14.02  ? 120 SER B N     1 
ATOM   2375 C CA    . SER D 3 120 ? -93.294  21.054 86.810 1.00 13.91  ? 120 SER B CA    1 
ATOM   2376 C C     . SER D 3 120 ? -91.880  20.522 86.971 1.00 22.22  ? 120 SER B C     1 
ATOM   2377 O O     . SER D 3 120 ? -91.290  20.616 88.045 1.00 34.49  ? 120 SER B O     1 
ATOM   2378 C CB    . SER D 3 120 ? -94.298  19.908 86.946 1.00 8.08   ? 120 SER B CB    1 
ATOM   2379 O OG    . SER D 3 120 ? -95.627  20.408 86.922 1.00 32.84  ? 120 SER B OG    1 
ATOM   2380 N N     . ALA D 3 121 ? -91.337  19.965 85.897 1.00 16.39  ? 121 ALA B N     1 
ATOM   2381 C CA    . ALA D 3 121 ? -89.994  19.425 85.940 1.00 17.26  ? 121 ALA B CA    1 
ATOM   2382 C C     . ALA D 3 121 ? -88.987  20.551 86.124 1.00 22.39  ? 121 ALA B C     1 
ATOM   2383 O O     . ALA D 3 121 ? -88.113  20.485 86.990 1.00 21.87  ? 121 ALA B O     1 
ATOM   2384 C CB    . ALA D 3 121 ? -89.704  18.666 84.662 1.00 9.70   ? 121 ALA B CB    1 
ATOM   2385 N N     . ILE D 3 122 ? -89.124  21.590 85.309 1.00 19.66  ? 122 ILE B N     1 
ATOM   2386 C CA    . ILE D 3 122 ? -88.215  22.721 85.368 1.00 16.95  ? 122 ILE B CA    1 
ATOM   2387 C C     . ILE D 3 122 ? -88.200  23.341 86.752 1.00 19.56  ? 122 ILE B C     1 
ATOM   2388 O O     . ILE D 3 122 ? -87.148  23.510 87.364 1.00 23.12  ? 122 ILE B O     1 
ATOM   2389 C CB    . ILE D 3 122 ? -88.618  23.811 84.365 1.00 15.09  ? 122 ILE B CB    1 
ATOM   2390 C CG1   . ILE D 3 122 ? -88.340  23.336 82.941 1.00 12.79  ? 122 ILE B CG1   1 
ATOM   2391 C CG2   . ILE D 3 122 ? -87.842  25.092 84.643 1.00 7.59   ? 122 ILE B CG2   1 
ATOM   2392 C CD1   . ILE D 3 122 ? -89.169  24.066 81.913 1.00 9.84   ? 122 ILE B CD1   1 
ATOM   2393 N N     . ALA D 3 123 ? -89.385  23.677 87.238 1.00 21.34  ? 123 ALA B N     1 
ATOM   2394 C CA    . ALA D 3 123 ? -89.531  24.309 88.536 1.00 20.39  ? 123 ALA B CA    1 
ATOM   2395 C C     . ALA D 3 123 ? -89.004  23.462 89.678 1.00 20.03  ? 123 ALA B C     1 
ATOM   2396 O O     . ALA D 3 123 ? -88.846  23.950 90.796 1.00 27.93  ? 123 ALA B O     1 
ATOM   2397 C CB    . ALA D 3 123 ? -90.977  24.636 88.772 1.00 6.21   ? 123 ALA B CB    1 
ATOM   2398 N N     . ALA D 3 124 ? -88.736  22.191 89.407 1.00 22.24  ? 124 ALA B N     1 
ATOM   2399 C CA    . ALA D 3 124 ? -88.238  21.307 90.453 1.00 16.12  ? 124 ALA B CA    1 
ATOM   2400 C C     . ALA D 3 124 ? -86.824  20.818 90.203 1.00 23.58  ? 124 ALA B C     1 
ATOM   2401 O O     . ALA D 3 124 ? -86.400  19.828 90.796 1.00 22.64  ? 124 ALA B O     1 
ATOM   2402 C CB    . ALA D 3 124 ? -89.154  20.130 90.607 1.00 2.00   ? 124 ALA B CB    1 
ATOM   2403 N N     . ASN D 3 125 ? -86.100  21.503 89.324 1.00 18.21  ? 125 ASN B N     1 
ATOM   2404 C CA    . ASN D 3 125 ? -84.728  21.122 89.023 1.00 21.51  ? 125 ASN B CA    1 
ATOM   2405 C C     . ASN D 3 125 ? -84.687  19.656 88.625 1.00 21.89  ? 125 ASN B C     1 
ATOM   2406 O O     . ASN D 3 125 ? -83.737  18.951 88.964 1.00 28.57  ? 125 ASN B O     1 
ATOM   2407 C CB    . ASN D 3 125 ? -83.845  21.329 90.258 1.00 10.22  ? 125 ASN B CB    1 
ATOM   2408 C CG    . ASN D 3 125 ? -83.142  22.669 90.261 1.00 26.21  ? 125 ASN B CG    1 
ATOM   2409 O OD1   . ASN D 3 125 ? -82.479  23.031 89.292 1.00 35.12  ? 125 ASN B OD1   1 
ATOM   2410 N ND2   . ASN D 3 125 ? -83.280  23.412 91.355 1.00 27.58  ? 125 ASN B ND2   1 
ATOM   2411 N N     . SER D 3 126 ? -85.711  19.205 87.904 1.00 20.20  ? 126 SER B N     1 
ATOM   2412 C CA    . SER D 3 126 ? -85.795  17.807 87.493 1.00 20.42  ? 126 SER B CA    1 
ATOM   2413 C C     . SER D 3 126 ? -85.972  17.551 86.011 1.00 21.35  ? 126 SER B C     1 
ATOM   2414 O O     . SER D 3 126 ? -86.150  18.466 85.211 1.00 23.67  ? 126 SER B O     1 
ATOM   2415 C CB    . SER D 3 126 ? -86.950  17.121 88.214 1.00 6.67   ? 126 SER B CB    1 
ATOM   2416 O OG    . SER D 3 126 ? -86.938  17.442 89.587 1.00 44.58  ? 126 SER B OG    1 
ATOM   2417 N N     . GLY D 3 127 ? -85.920  16.271 85.668 1.00 17.34  ? 127 GLY B N     1 
ATOM   2418 C CA    . GLY D 3 127 ? -86.122  15.853 84.301 1.00 12.76  ? 127 GLY B CA    1 
ATOM   2419 C C     . GLY D 3 127 ? -87.447  15.123 84.334 1.00 22.37  ? 127 GLY B C     1 
ATOM   2420 O O     . GLY D 3 127 ? -88.256  15.366 85.229 1.00 25.83  ? 127 GLY B O     1 
ATOM   2421 N N     . ILE D 3 128 ? -87.675  14.230 83.379 1.00 23.27  ? 128 ILE B N     1 
ATOM   2422 C CA    . ILE D 3 128 ? -88.911  13.461 83.333 1.00 22.24  ? 128 ILE B CA    1 
ATOM   2423 C C     . ILE D 3 128 ? -88.634  12.084 83.921 1.00 23.22  ? 128 ILE B C     1 
ATOM   2424 O O     . ILE D 3 128 ? -87.550  11.536 83.742 1.00 32.69  ? 128 ILE B O     1 
ATOM   2425 C CB    . ILE D 3 128 ? -89.413  13.314 81.886 1.00 22.04  ? 128 ILE B CB    1 
ATOM   2426 C CG1   . ILE D 3 128 ? -89.564  14.702 81.251 1.00 20.71  ? 128 ILE B CG1   1 
ATOM   2427 C CG2   . ILE D 3 128 ? -90.730  12.566 81.861 1.00 13.20  ? 128 ILE B CG2   1 
ATOM   2428 C CD1   . ILE D 3 128 ? -90.621  15.571 81.897 1.00 12.67  ? 128 ILE B CD1   1 
ATOM   2429 N N     . TYR D 3 129 ? -89.609  11.529 84.632 1.00 26.25  ? 129 TYR B N     1 
ATOM   2430 C CA    . TYR D 3 129 ? -89.441  10.215 85.251 1.00 26.74  ? 129 TYR B CA    1 
ATOM   2431 C C     . TYR D 3 129 ? -90.795  9.588  85.570 1.00 32.86  ? 129 TYR B C     1 
ATOM   2432 O O     . TYR D 3 129 ? -91.797  10.338 85.608 1.00 29.86  ? 129 TYR B O     1 
ATOM   2433 C CB    . TYR D 3 129 ? -88.631  10.349 86.540 1.00 16.82  ? 129 TYR B CB    1 
ATOM   2434 C CG    . TYR D 3 129 ? -89.278  11.289 87.525 1.00 22.15  ? 129 TYR B CG    1 
ATOM   2435 C CD1   . TYR D 3 129 ? -89.007  12.660 87.493 1.00 23.56  ? 129 TYR B CD1   1 
ATOM   2436 C CD2   . TYR D 3 129 ? -90.209  10.819 88.453 1.00 16.13  ? 129 TYR B CD2   1 
ATOM   2437 C CE1   . TYR D 3 129 ? -89.655  13.544 88.360 1.00 22.20  ? 129 TYR B CE1   1 
ATOM   2438 C CE2   . TYR D 3 129 ? -90.864  11.692 89.328 1.00 15.35  ? 129 TYR B CE2   1 
ATOM   2439 C CZ    . TYR D 3 129 ? -90.585  13.051 89.275 1.00 27.89  ? 129 TYR B CZ    1 
ATOM   2440 O OH    . TYR D 3 129 ? -91.239  13.909 90.131 1.00 35.10  ? 129 TYR B OH    1 
ATOM   2441 O OXT   . TYR D 3 129 ? -90.838  8.355  85.783 1.00 45.75  ? 129 TYR B OXT   1 
ATOM   2442 N N     . ALA E 3 1   ? -91.974  58.774 68.641 1.00 81.53  ? 1   ALA C N     1 
ATOM   2443 C CA    . ALA E 3 1   ? -92.411  58.994 67.230 1.00 83.17  ? 1   ALA C CA    1 
ATOM   2444 C C     . ALA E 3 1   ? -92.081  57.785 66.360 1.00 77.88  ? 1   ALA C C     1 
ATOM   2445 O O     . ALA E 3 1   ? -91.092  57.082 66.599 1.00 73.86  ? 1   ALA C O     1 
ATOM   2446 C CB    . ALA E 3 1   ? -91.742  60.245 66.663 1.00 81.05  ? 1   ALA C CB    1 
ATOM   2447 N N     . SER E 3 2   ? -92.915  57.544 65.352 1.00 62.89  ? 2   SER C N     1 
ATOM   2448 C CA    . SER E 3 2   ? -92.695  56.419 64.459 1.00 45.70  ? 2   SER C CA    1 
ATOM   2449 C C     . SER E 3 2   ? -93.583  56.490 63.243 1.00 37.58  ? 2   SER C C     1 
ATOM   2450 O O     . SER E 3 2   ? -94.771  56.771 63.347 1.00 40.55  ? 2   SER C O     1 
ATOM   2451 C CB    . SER E 3 2   ? -92.957  55.102 65.188 1.00 41.99  ? 2   SER C CB    1 
ATOM   2452 O OG    . SER E 3 2   ? -92.249  54.034 64.586 1.00 49.96  ? 2   SER C OG    1 
ATOM   2453 N N     . ASN E 3 3   ? -92.998  56.255 62.078 1.00 28.17  ? 3   ASN C N     1 
ATOM   2454 C CA    . ASN E 3 3   ? -93.780  56.249 60.861 1.00 29.99  ? 3   ASN C CA    1 
ATOM   2455 C C     . ASN E 3 3   ? -93.817  54.807 60.370 1.00 31.46  ? 3   ASN C C     1 
ATOM   2456 O O     . ASN E 3 3   ? -94.373  54.499 59.315 1.00 35.86  ? 3   ASN C O     1 
ATOM   2457 C CB    . ASN E 3 3   ? -93.194  57.204 59.808 1.00 23.55  ? 3   ASN C CB    1 
ATOM   2458 C CG    . ASN E 3 3   ? -91.870  56.746 59.258 1.00 25.71  ? 3   ASN C CG    1 
ATOM   2459 O OD1   . ASN E 3 3   ? -91.324  55.718 59.660 1.00 47.08  ? 3   ASN C OD1   1 
ATOM   2460 N ND2   . ASN E 3 3   ? -91.337  57.518 58.322 1.00 39.40  ? 3   ASN C ND2   1 
ATOM   2461 N N     . PHE E 3 4   ? -93.222  53.921 61.163 1.00 27.01  ? 4   PHE C N     1 
ATOM   2462 C CA    . PHE E 3 4   ? -93.215  52.501 60.850 1.00 28.45  ? 4   PHE C CA    1 
ATOM   2463 C C     . PHE E 3 4   ? -94.408  51.874 61.559 1.00 29.95  ? 4   PHE C C     1 
ATOM   2464 O O     . PHE E 3 4   ? -94.249  51.036 62.443 1.00 24.36  ? 4   PHE C O     1 
ATOM   2465 C CB    . PHE E 3 4   ? -91.933  51.839 61.348 1.00 23.19  ? 4   PHE C CB    1 
ATOM   2466 C CG    . PHE E 3 4   ? -91.781  50.402 60.920 1.00 25.78  ? 4   PHE C CG    1 
ATOM   2467 C CD1   . PHE E 3 4   ? -92.146  50.000 59.638 1.00 29.33  ? 4   PHE C CD1   1 
ATOM   2468 C CD2   . PHE E 3 4   ? -91.227  49.460 61.782 1.00 29.23  ? 4   PHE C CD2   1 
ATOM   2469 C CE1   . PHE E 3 4   ? -91.954  48.682 59.220 1.00 29.63  ? 4   PHE C CE1   1 
ATOM   2470 C CE2   . PHE E 3 4   ? -91.031  48.143 61.373 1.00 32.24  ? 4   PHE C CE2   1 
ATOM   2471 C CZ    . PHE E 3 4   ? -91.395  47.753 60.089 1.00 26.82  ? 4   PHE C CZ    1 
ATOM   2472 N N     . THR E 3 5   ? -95.603  52.301 61.177 1.00 24.11  ? 5   THR C N     1 
ATOM   2473 C CA    . THR E 3 5   ? -96.818  51.781 61.776 1.00 33.55  ? 5   THR C CA    1 
ATOM   2474 C C     . THR E 3 5   ? -97.701  51.221 60.691 1.00 29.90  ? 5   THR C C     1 
ATOM   2475 O O     . THR E 3 5   ? -97.375  51.290 59.510 1.00 29.63  ? 5   THR C O     1 
ATOM   2476 C CB    . THR E 3 5   ? -97.597  52.870 62.460 1.00 34.08  ? 5   THR C CB    1 
ATOM   2477 O OG1   . THR E 3 5   ? -97.553  54.039 61.637 1.00 23.93  ? 5   THR C OG1   1 
ATOM   2478 C CG2   . THR E 3 5   ? -97.010  53.163 63.836 1.00 60.73  ? 5   THR C CG2   1 
ATOM   2479 N N     . GLN E 3 6   ? -98.840  50.681 61.091 1.00 25.29  ? 6   GLN C N     1 
ATOM   2480 C CA    . GLN E 3 6   ? -99.730  50.111 60.114 1.00 25.92  ? 6   GLN C CA    1 
ATOM   2481 C C     . GLN E 3 6   ? -100.543 51.181 59.433 1.00 20.73  ? 6   GLN C C     1 
ATOM   2482 O O     . GLN E 3 6   ? -100.781 52.249 59.990 1.00 33.49  ? 6   GLN C O     1 
ATOM   2483 C CB    . GLN E 3 6   ? -100.637 49.077 60.767 1.00 21.71  ? 6   GLN C CB    1 
ATOM   2484 C CG    . GLN E 3 6   ? -101.901 49.616 61.370 1.00 36.40  ? 6   GLN C CG    1 
ATOM   2485 C CD    . GLN E 3 6   ? -102.684 48.523 62.071 1.00 58.01  ? 6   GLN C CD    1 
ATOM   2486 O OE1   . GLN E 3 6   ? -103.102 48.683 63.216 1.00 72.57  ? 6   GLN C OE1   1 
ATOM   2487 N NE2   . GLN E 3 6   ? -102.880 47.398 61.387 1.00 50.19  ? 6   GLN C NE2   1 
ATOM   2488 N N     . PHE E 3 7   ? -100.944 50.893 58.205 1.00 22.94  ? 7   PHE C N     1 
ATOM   2489 C CA    . PHE E 3 7   ? -101.743 51.823 57.445 1.00 16.30  ? 7   PHE C CA    1 
ATOM   2490 C C     . PHE E 3 7   ? -102.638 51.091 56.467 1.00 23.67  ? 7   PHE C C     1 
ATOM   2491 O O     . PHE E 3 7   ? -102.470 49.892 56.225 1.00 31.77  ? 7   PHE C O     1 
ATOM   2492 C CB    . PHE E 3 7   ? -100.846 52.838 56.714 1.00 15.74  ? 7   PHE C CB    1 
ATOM   2493 C CG    . PHE E 3 7   ? -99.978  52.248 55.635 1.00 15.44  ? 7   PHE C CG    1 
ATOM   2494 C CD1   . PHE E 3 7   ? -98.758  51.652 55.950 1.00 20.03  ? 7   PHE C CD1   1 
ATOM   2495 C CD2   . PHE E 3 7   ? -100.354 52.338 54.294 1.00 17.35  ? 7   PHE C CD2   1 
ATOM   2496 C CE1   . PHE E 3 7   ? -97.918  51.157 54.945 1.00 19.71  ? 7   PHE C CE1   1 
ATOM   2497 C CE2   . PHE E 3 7   ? -99.521  51.847 53.281 1.00 21.14  ? 7   PHE C CE2   1 
ATOM   2498 C CZ    . PHE E 3 7   ? -98.300  51.255 53.608 1.00 12.86  ? 7   PHE C CZ    1 
ATOM   2499 N N     . VAL E 3 8   ? -103.608 51.818 55.926 1.00 18.25  ? 8   VAL C N     1 
ATOM   2500 C CA    . VAL E 3 8   ? -104.536 51.260 54.961 1.00 21.37  ? 8   VAL C CA    1 
ATOM   2501 C C     . VAL E 3 8   ? -103.937 51.384 53.571 1.00 25.65  ? 8   VAL C C     1 
ATOM   2502 O O     . VAL E 3 8   ? -103.746 52.489 53.063 1.00 31.37  ? 8   VAL C O     1 
ATOM   2503 C CB    . VAL E 3 8   ? -105.871 52.008 54.980 1.00 15.76  ? 8   VAL C CB    1 
ATOM   2504 C CG1   . VAL E 3 8   ? -106.841 51.368 53.996 1.00 23.08  ? 8   VAL C CG1   1 
ATOM   2505 C CG2   . VAL E 3 8   ? -106.441 51.999 56.374 1.00 2.00   ? 8   VAL C CG2   1 
ATOM   2506 N N     . LEU E 3 9   ? -103.633 50.245 52.964 1.00 26.86  ? 9   LEU C N     1 
ATOM   2507 C CA    . LEU E 3 9   ? -103.059 50.229 51.630 1.00 25.07  ? 9   LEU C CA    1 
ATOM   2508 C C     . LEU E 3 9   ? -104.174 50.355 50.609 1.00 25.64  ? 9   LEU C C     1 
ATOM   2509 O O     . LEU E 3 9   ? -104.040 51.073 49.620 1.00 28.41  ? 9   LEU C O     1 
ATOM   2510 C CB    . LEU E 3 9   ? -102.306 48.927 51.398 1.00 19.76  ? 9   LEU C CB    1 
ATOM   2511 C CG    . LEU E 3 9   ? -101.729 48.774 49.998 1.00 20.45  ? 9   LEU C CG    1 
ATOM   2512 C CD1   . LEU E 3 9   ? -100.646 49.820 49.788 1.00 15.70  ? 9   LEU C CD1   1 
ATOM   2513 C CD2   . LEU E 3 9   ? -101.177 47.366 49.831 1.00 14.90  ? 9   LEU C CD2   1 
ATOM   2514 N N     . VAL E 3 10  ? -105.268 49.641 50.851 1.00 24.86  ? 10  VAL C N     1 
ATOM   2515 C CA    . VAL E 3 10  ? -106.419 49.678 49.960 1.00 22.69  ? 10  VAL C CA    1 
ATOM   2516 C C     . VAL E 3 10  ? -107.637 50.140 50.731 1.00 22.89  ? 10  VAL C C     1 
ATOM   2517 O O     . VAL E 3 10  ? -108.073 49.476 51.668 1.00 28.63  ? 10  VAL C O     1 
ATOM   2518 C CB    . VAL E 3 10  ? -106.732 48.298 49.355 1.00 27.85  ? 10  VAL C CB    1 
ATOM   2519 C CG1   . VAL E 3 10  ? -107.898 48.413 48.375 1.00 14.57  ? 10  VAL C CG1   1 
ATOM   2520 C CG2   . VAL E 3 10  ? -105.505 47.753 48.654 1.00 23.64  ? 10  VAL C CG2   1 
ATOM   2521 N N     . ASP E 3 11  ? -108.170 51.288 50.326 1.00 35.10  ? 11  ASP C N     1 
ATOM   2522 C CA    . ASP E 3 11  ? -109.346 51.895 50.942 1.00 39.69  ? 11  ASP C CA    1 
ATOM   2523 C C     . ASP E 3 11  ? -110.612 51.483 50.194 1.00 48.34  ? 11  ASP C C     1 
ATOM   2524 O O     . ASP E 3 11  ? -111.075 52.186 49.296 1.00 53.58  ? 11  ASP C O     1 
ATOM   2525 C CB    . ASP E 3 11  ? -109.203 53.419 50.913 1.00 45.44  ? 11  ASP C CB    1 
ATOM   2526 C CG    . ASP E 3 11  ? -110.238 54.121 51.764 1.00 55.84  ? 11  ASP C CG    1 
ATOM   2527 O OD1   . ASP E 3 11  ? -111.226 53.463 52.152 1.00 54.65  ? 11  ASP C OD1   1 
ATOM   2528 O OD2   . ASP E 3 11  ? -110.057 55.328 52.044 1.00 61.05  ? 11  ASP C OD2   1 
ATOM   2529 N N     . ASN E 3 12  ? -111.163 50.332 50.560 1.00 59.78  ? 12  ASN C N     1 
ATOM   2530 C CA    . ASN E 3 12  ? -112.371 49.830 49.924 1.00 65.76  ? 12  ASN C CA    1 
ATOM   2531 C C     . ASN E 3 12  ? -113.549 50.197 50.803 1.00 73.26  ? 12  ASN C C     1 
ATOM   2532 O O     . ASN E 3 12  ? -114.238 49.326 51.333 1.00 88.50  ? 12  ASN C O     1 
ATOM   2533 C CB    . ASN E 3 12  ? -112.289 48.314 49.770 1.00 65.54  ? 12  ASN C CB    1 
ATOM   2534 C CG    . ASN E 3 12  ? -112.186 47.886 48.326 1.00 85.72  ? 12  ASN C CG    1 
ATOM   2535 O OD1   . ASN E 3 12  ? -112.443 48.676 47.414 1.00 85.14  ? 12  ASN C OD1   1 
ATOM   2536 N ND2   . ASN E 3 12  ? -111.807 46.632 48.105 1.00 96.92  ? 12  ASN C ND2   1 
ATOM   2537 N N     . GLY E 3 13  ? -113.779 51.494 50.954 1.00 69.34  ? 13  GLY C N     1 
ATOM   2538 C CA    . GLY E 3 13  ? -114.861 51.946 51.803 1.00 81.64  ? 13  GLY C CA    1 
ATOM   2539 C C     . GLY E 3 13  ? -114.366 51.916 53.236 1.00 90.41  ? 13  GLY C C     1 
ATOM   2540 O O     . GLY E 3 13  ? -113.303 52.457 53.540 1.00 100.00 ? 13  GLY C O     1 
ATOM   2541 N N     . GLY E 3 14  ? -115.124 51.282 54.122 1.00 92.17  ? 14  GLY C N     1 
ATOM   2542 C CA    . GLY E 3 14  ? -114.705 51.199 55.509 1.00 95.06  ? 14  GLY C CA    1 
ATOM   2543 C C     . GLY E 3 14  ? -114.753 49.763 55.992 1.00 100.00 ? 14  GLY C C     1 
ATOM   2544 O O     . GLY E 3 14  ? -114.629 49.492 57.187 1.00 100.00 ? 14  GLY C O     1 
ATOM   2545 N N     . THR E 3 15  ? -114.921 48.836 55.054 1.00 99.23  ? 15  THR C N     1 
ATOM   2546 C CA    . THR E 3 15  ? -115.010 47.422 55.387 1.00 100.00 ? 15  THR C CA    1 
ATOM   2547 C C     . THR E 3 15  ? -113.972 46.546 54.681 1.00 99.80  ? 15  THR C C     1 
ATOM   2548 O O     . THR E 3 15  ? -113.044 46.046 55.322 1.00 100.00 ? 15  THR C O     1 
ATOM   2549 C CB    . THR E 3 15  ? -116.415 46.892 55.067 1.00 100.00 ? 15  THR C CB    1 
ATOM   2550 O OG1   . THR E 3 15  ? -116.740 47.195 53.702 1.00 100.00 ? 15  THR C OG1   1 
ATOM   2551 C CG2   . THR E 3 15  ? -117.447 47.541 55.993 1.00 100.00 ? 15  THR C CG2   1 
ATOM   2552 N N     . GLY E 3 16  ? -114.131 46.357 53.371 1.00 90.18  ? 16  GLY C N     1 
ATOM   2553 C CA    . GLY E 3 16  ? -113.191 45.540 52.617 1.00 79.58  ? 16  GLY C CA    1 
ATOM   2554 C C     . GLY E 3 16  ? -111.809 46.169 52.512 1.00 75.54  ? 16  GLY C C     1 
ATOM   2555 O O     . GLY E 3 16  ? -111.094 45.965 51.529 1.00 69.08  ? 16  GLY C O     1 
ATOM   2556 N N     . ASP E 3 17  ? -111.441 46.930 53.540 1.00 64.57  ? 17  ASP C N     1 
ATOM   2557 C CA    . ASP E 3 17  ? -110.162 47.625 53.609 1.00 46.08  ? 17  ASP C CA    1 
ATOM   2558 C C     . ASP E 3 17  ? -108.988 46.688 53.786 1.00 42.33  ? 17  ASP C C     1 
ATOM   2559 O O     . ASP E 3 17  ? -109.053 45.749 54.576 1.00 56.10  ? 17  ASP C O     1 
ATOM   2560 C CB    . ASP E 3 17  ? -110.159 48.602 54.782 1.00 43.54  ? 17  ASP C CB    1 
ATOM   2561 C CG    . ASP E 3 17  ? -110.943 49.856 54.498 1.00 51.45  ? 17  ASP C CG    1 
ATOM   2562 O OD1   . ASP E 3 17  ? -111.556 49.934 53.412 1.00 53.68  ? 17  ASP C OD1   1 
ATOM   2563 O OD2   . ASP E 3 17  ? -110.945 50.763 55.363 1.00 48.84  ? 17  ASP C OD2   1 
ATOM   2564 N N     . VAL E 3 18  ? -107.910 46.951 53.055 1.00 36.46  ? 18  VAL C N     1 
ATOM   2565 C CA    . VAL E 3 18  ? -106.715 46.136 53.189 1.00 26.88  ? 18  VAL C CA    1 
ATOM   2566 C C     . VAL E 3 18  ? -105.714 46.929 54.006 1.00 30.69  ? 18  VAL C C     1 
ATOM   2567 O O     . VAL E 3 18  ? -105.198 47.958 53.568 1.00 27.66  ? 18  VAL C O     1 
ATOM   2568 C CB    . VAL E 3 18  ? -106.082 45.785 51.836 1.00 23.92  ? 18  VAL C CB    1 
ATOM   2569 C CG1   . VAL E 3 18  ? -104.757 45.061 52.056 1.00 13.66  ? 18  VAL C CG1   1 
ATOM   2570 C CG2   . VAL E 3 18  ? -107.015 44.904 51.049 1.00 17.56  ? 18  VAL C CG2   1 
ATOM   2571 N N     . THR E 3 19  ? -105.471 46.459 55.219 1.00 33.60  ? 19  THR C N     1 
ATOM   2572 C CA    . THR E 3 19  ? -104.524 47.109 56.091 1.00 19.55  ? 19  THR C CA    1 
ATOM   2573 C C     . THR E 3 19  ? -103.261 46.285 56.100 1.00 21.90  ? 19  THR C C     1 
ATOM   2574 O O     . THR E 3 19  ? -103.287 45.052 56.122 1.00 36.59  ? 19  THR C O     1 
ATOM   2575 C CB    . THR E 3 19  ? -105.052 47.227 57.509 1.00 17.86  ? 19  THR C CB    1 
ATOM   2576 O OG1   . THR E 3 19  ? -105.934 48.348 57.582 1.00 36.50  ? 19  THR C OG1   1 
ATOM   2577 C CG2   . THR E 3 19  ? -103.910 47.435 58.485 1.00 42.19  ? 19  THR C CG2   1 
ATOM   2578 N N     . VAL E 3 20  ? -102.150 46.993 56.090 1.00 25.03  ? 20  VAL C N     1 
ATOM   2579 C CA    . VAL E 3 20  ? -100.851 46.375 56.068 1.00 25.27  ? 20  VAL C CA    1 
ATOM   2580 C C     . VAL E 3 20  ? -100.139 46.803 57.357 1.00 25.74  ? 20  VAL C C     1 
ATOM   2581 O O     . VAL E 3 20  ? -100.264 47.951 57.785 1.00 21.56  ? 20  VAL C O     1 
ATOM   2582 C CB    . VAL E 3 20  ? -100.150 46.836 54.776 1.00 23.25  ? 20  VAL C CB    1 
ATOM   2583 C CG1   . VAL E 3 20  ? -99.044  47.817 55.079 1.00 32.24  ? 20  VAL C CG1   1 
ATOM   2584 C CG2   . VAL E 3 20  ? -99.686  45.632 54.002 1.00 36.01  ? 20  VAL C CG2   1 
ATOM   2585 N N     . ALA E 3 21  ? -99.417  45.882 57.992 1.00 20.88  ? 21  ALA C N     1 
ATOM   2586 C CA    . ALA E 3 21  ? -98.741  46.197 59.255 1.00 21.71  ? 21  ALA C CA    1 
ATOM   2587 C C     . ALA E 3 21  ? -97.264  45.851 59.315 1.00 23.34  ? 21  ALA C C     1 
ATOM   2588 O O     . ALA E 3 21  ? -96.805  44.926 58.648 1.00 33.63  ? 21  ALA C O     1 
ATOM   2589 C CB    . ALA E 3 21  ? -99.444  45.508 60.392 1.00 7.48   ? 21  ALA C CB    1 
ATOM   2590 N N     . PRO E 3 22  ? -96.497  46.592 60.135 1.00 23.37  ? 22  PRO C N     1 
ATOM   2591 C CA    . PRO E 3 22  ? -95.059  46.342 60.273 1.00 18.85  ? 22  PRO C CA    1 
ATOM   2592 C C     . PRO E 3 22  ? -94.770  44.862 60.497 1.00 24.80  ? 22  PRO C C     1 
ATOM   2593 O O     . PRO E 3 22  ? -95.427  44.193 61.296 1.00 33.77  ? 22  PRO C O     1 
ATOM   2594 C CB    . PRO E 3 22  ? -94.658  47.206 61.464 1.00 8.51   ? 22  PRO C CB    1 
ATOM   2595 C CG    . PRO E 3 22  ? -95.632  48.340 61.419 1.00 21.38  ? 22  PRO C CG    1 
ATOM   2596 C CD    . PRO E 3 22  ? -96.934  47.724 60.971 1.00 17.91  ? 22  PRO C CD    1 
ATOM   2597 N N     . SER E 3 23  ? -93.785  44.348 59.777 1.00 19.64  ? 23  SER C N     1 
ATOM   2598 C CA    . SER E 3 23  ? -93.440  42.948 59.892 1.00 23.26  ? 23  SER C CA    1 
ATOM   2599 C C     . SER E 3 23  ? -91.982  42.765 60.275 1.00 21.36  ? 23  SER C C     1 
ATOM   2600 O O     . SER E 3 23  ? -91.647  42.017 61.193 1.00 43.81  ? 23  SER C O     1 
ATOM   2601 C CB    . SER E 3 23  ? -93.717  42.243 58.563 1.00 18.91  ? 23  SER C CB    1 
ATOM   2602 O OG    . SER E 3 23  ? -92.547  41.623 58.064 1.00 43.88  ? 23  SER C OG    1 
ATOM   2603 N N     . ASN E 3 24  ? -91.110  43.472 59.580 1.00 18.74  ? 24  ASN C N     1 
ATOM   2604 C CA    . ASN E 3 24  ? -89.696  43.333 59.839 1.00 23.37  ? 24  ASN C CA    1 
ATOM   2605 C C     . ASN E 3 24  ? -88.981  44.575 59.321 1.00 19.09  ? 24  ASN C C     1 
ATOM   2606 O O     . ASN E 3 24  ? -89.448  45.212 58.384 1.00 29.06  ? 24  ASN C O     1 
ATOM   2607 C CB    . ASN E 3 24  ? -89.220  42.059 59.131 1.00 20.21  ? 24  ASN C CB    1 
ATOM   2608 C CG    . ASN E 3 24  ? -87.732  42.019 58.931 1.00 47.81  ? 24  ASN C CG    1 
ATOM   2609 O OD1   . ASN E 3 24  ? -87.219  42.513 57.923 1.00 63.20  ? 24  ASN C OD1   1 
ATOM   2610 N ND2   . ASN E 3 24  ? -87.019  41.423 59.887 1.00 55.32  ? 24  ASN C ND2   1 
ATOM   2611 N N     . PHE E 3 25  ? -87.864  44.934 59.943 1.00 24.65  ? 25  PHE C N     1 
ATOM   2612 C CA    . PHE E 3 25  ? -87.103  46.103 59.515 1.00 20.85  ? 25  PHE C CA    1 
ATOM   2613 C C     . PHE E 3 25  ? -85.618  45.786 59.565 1.00 23.43  ? 25  PHE C C     1 
ATOM   2614 O O     . PHE E 3 25  ? -84.852  46.483 60.219 1.00 41.61  ? 25  PHE C O     1 
ATOM   2615 C CB    . PHE E 3 25  ? -87.407  47.306 60.418 1.00 24.85  ? 25  PHE C CB    1 
ATOM   2616 C CG    . PHE E 3 25  ? -86.895  48.630 59.885 1.00 24.87  ? 25  PHE C CG    1 
ATOM   2617 C CD1   . PHE E 3 25  ? -86.178  48.702 58.693 1.00 29.15  ? 25  PHE C CD1   1 
ATOM   2618 C CD2   . PHE E 3 25  ? -87.145  49.810 60.578 1.00 24.20  ? 25  PHE C CD2   1 
ATOM   2619 C CE1   . PHE E 3 25  ? -85.720  49.929 58.202 1.00 25.54  ? 25  PHE C CE1   1 
ATOM   2620 C CE2   . PHE E 3 25  ? -86.689  51.042 60.092 1.00 26.09  ? 25  PHE C CE2   1 
ATOM   2621 C CZ    . PHE E 3 25  ? -85.977  51.098 58.903 1.00 18.90  ? 25  PHE C CZ    1 
ATOM   2622 N N     . ALA E 3 26  ? -85.215  44.737 58.859 1.00 21.69  ? 26  ALA C N     1 
ATOM   2623 C CA    . ALA E 3 26  ? -83.819  44.326 58.836 1.00 24.39  ? 26  ALA C CA    1 
ATOM   2624 C C     . ALA E 3 26  ? -83.052  44.841 57.628 1.00 34.97  ? 26  ALA C C     1 
ATOM   2625 O O     . ALA E 3 26  ? -83.584  44.903 56.519 1.00 38.92  ? 26  ALA C O     1 
ATOM   2626 C CB    . ALA E 3 26  ? -83.735  42.830 58.874 1.00 23.31  ? 26  ALA C CB    1 
ATOM   2627 N N     . ASN E 3 27  ? -81.792  45.195 57.860 1.00 40.20  ? 27  ASN C N     1 
ATOM   2628 C CA    . ASN E 3 27  ? -80.904  45.691 56.815 1.00 41.20  ? 27  ASN C CA    1 
ATOM   2629 C C     . ASN E 3 27  ? -81.418  46.921 56.075 1.00 37.34  ? 27  ASN C C     1 
ATOM   2630 O O     . ASN E 3 27  ? -81.286  47.029 54.857 1.00 44.89  ? 27  ASN C O     1 
ATOM   2631 C CB    . ASN E 3 27  ? -80.604  44.573 55.816 1.00 43.54  ? 27  ASN C CB    1 
ATOM   2632 C CG    . ASN E 3 27  ? -79.870  43.418 56.454 1.00 62.02  ? 27  ASN C CG    1 
ATOM   2633 O OD1   . ASN E 3 27  ? -80.375  42.296 56.499 1.00 77.25  ? 27  ASN C OD1   1 
ATOM   2634 N ND2   . ASN E 3 27  ? -78.670  43.686 56.960 1.00 66.78  ? 27  ASN C ND2   1 
ATOM   2635 N N     . GLY E 3 28  ? -81.998  47.851 56.820 1.00 27.98  ? 28  GLY C N     1 
ATOM   2636 C CA    . GLY E 3 28  ? -82.500  49.065 56.210 1.00 24.61  ? 28  GLY C CA    1 
ATOM   2637 C C     . GLY E 3 28  ? -83.724  48.901 55.334 1.00 20.43  ? 28  GLY C C     1 
ATOM   2638 O O     . GLY E 3 28  ? -84.085  49.818 54.604 1.00 29.16  ? 28  GLY C O     1 
ATOM   2639 N N     . VAL E 3 29  ? -84.372  47.745 55.386 1.00 20.72  ? 29  VAL C N     1 
ATOM   2640 C CA    . VAL E 3 29  ? -85.562  47.551 54.574 1.00 19.16  ? 29  VAL C CA    1 
ATOM   2641 C C     . VAL E 3 29  ? -86.797  47.351 55.431 1.00 21.96  ? 29  VAL C C     1 
ATOM   2642 O O     . VAL E 3 29  ? -86.959  46.312 56.074 1.00 27.93  ? 29  VAL C O     1 
ATOM   2643 C CB    . VAL E 3 29  ? -85.429  46.344 53.628 1.00 16.08  ? 29  VAL C CB    1 
ATOM   2644 C CG1   . VAL E 3 29  ? -86.667  46.238 52.749 1.00 19.92  ? 29  VAL C CG1   1 
ATOM   2645 C CG2   . VAL E 3 29  ? -84.206  46.503 52.764 1.00 14.42  ? 29  VAL C CG2   1 
ATOM   2646 N N     . ALA E 3 30  ? -87.661  48.362 55.434 1.00 21.25  ? 30  ALA C N     1 
ATOM   2647 C CA    . ALA E 3 30  ? -88.902  48.313 56.187 1.00 20.31  ? 30  ALA C CA    1 
ATOM   2648 C C     . ALA E 3 30  ? -89.888  47.477 55.384 1.00 19.73  ? 30  ALA C C     1 
ATOM   2649 O O     . ALA E 3 30  ? -90.006  47.642 54.170 1.00 30.38  ? 30  ALA C O     1 
ATOM   2650 C CB    . ALA E 3 30  ? -89.448  49.720 56.392 1.00 15.20  ? 30  ALA C CB    1 
ATOM   2651 N N     . GLU E 3 31  ? -90.584  46.571 56.060 1.00 17.11  ? 31  GLU C N     1 
ATOM   2652 C CA    . GLU E 3 31  ? -91.549  45.717 55.393 1.00 17.52  ? 31  GLU C CA    1 
ATOM   2653 C C     . GLU E 3 31  ? -92.869  45.640 56.140 1.00 24.65  ? 31  GLU C C     1 
ATOM   2654 O O     . GLU E 3 31  ? -92.898  45.423 57.350 1.00 26.47  ? 31  GLU C O     1 
ATOM   2655 C CB    . GLU E 3 31  ? -90.992  44.308 55.238 1.00 17.75  ? 31  GLU C CB    1 
ATOM   2656 C CG    . GLU E 3 31  ? -92.061  43.258 54.985 1.00 31.32  ? 31  GLU C CG    1 
ATOM   2657 C CD    . GLU E 3 31  ? -91.477  41.879 54.795 1.00 30.65  ? 31  GLU C CD    1 
ATOM   2658 O OE1   . GLU E 3 31  ? -90.584  41.718 53.933 1.00 43.40  ? 31  GLU C OE1   1 
ATOM   2659 O OE2   . GLU E 3 31  ? -91.908  40.955 55.509 1.00 48.18  ? 31  GLU C OE2   1 
ATOM   2660 N N     . TRP E 3 32  ? -93.956  45.812 55.396 1.00 24.42  ? 32  TRP C N     1 
ATOM   2661 C CA    . TRP E 3 32  ? -95.304  45.744 55.939 1.00 15.61  ? 32  TRP C CA    1 
ATOM   2662 C C     . TRP E 3 32  ? -95.986  44.562 55.258 1.00 18.65  ? 32  TRP C C     1 
ATOM   2663 O O     . TRP E 3 32  ? -95.699  44.270 54.097 1.00 24.23  ? 32  TRP C O     1 
ATOM   2664 C CB    . TRP E 3 32  ? -96.081  47.004 55.593 1.00 15.74  ? 32  TRP C CB    1 
ATOM   2665 C CG    . TRP E 3 32  ? -95.686  48.245 56.319 1.00 21.50  ? 32  TRP C CG    1 
ATOM   2666 C CD1   . TRP E 3 32  ? -96.319  48.798 57.397 1.00 24.25  ? 32  TRP C CD1   1 
ATOM   2667 C CD2   . TRP E 3 32  ? -94.657  49.168 55.941 1.00 20.17  ? 32  TRP C CD2   1 
ATOM   2668 N NE1   . TRP E 3 32  ? -95.755  50.010 57.708 1.00 22.82  ? 32  TRP C NE1   1 
ATOM   2669 C CE2   . TRP E 3 32  ? -94.733  50.264 56.831 1.00 15.52  ? 32  TRP C CE2   1 
ATOM   2670 C CE3   . TRP E 3 32  ? -93.681  49.177 54.933 1.00 15.57  ? 32  TRP C CE3   1 
ATOM   2671 C CZ2   . TRP E 3 32  ? -93.869  51.363 56.745 1.00 18.12  ? 32  TRP C CZ2   1 
ATOM   2672 C CZ3   . TRP E 3 32  ? -92.821  50.270 54.846 1.00 13.39  ? 32  TRP C CZ3   1 
ATOM   2673 C CH2   . TRP E 3 32  ? -92.923  51.350 55.751 1.00 19.94  ? 32  TRP C CH2   1 
ATOM   2674 N N     . ILE E 3 33  ? -96.894  43.900 55.970 1.00 19.89  ? 33  ILE C N     1 
ATOM   2675 C CA    . ILE E 3 33  ? -97.623  42.747 55.435 1.00 15.59  ? 33  ILE C CA    1 
ATOM   2676 C C     . ILE E 3 33  ? -99.053  42.762 55.958 1.00 19.23  ? 33  ILE C C     1 
ATOM   2677 O O     . ILE E 3 33  ? -99.274  43.082 57.120 1.00 25.86  ? 33  ILE C O     1 
ATOM   2678 C CB    . ILE E 3 33  ? -96.977  41.423 55.887 1.00 13.61  ? 33  ILE C CB    1 
ATOM   2679 C CG1   . ILE E 3 33  ? -95.548  41.325 55.355 1.00 29.87  ? 33  ILE C CG1   1 
ATOM   2680 C CG2   . ILE E 3 33  ? -97.797  40.253 55.397 1.00 27.56  ? 33  ILE C CG2   1 
ATOM   2681 C CD1   . ILE E 3 33  ? -95.450  40.748 53.962 1.00 33.26  ? 33  ILE C CD1   1 
ATOM   2682 N N     . SER E 3 34  ? -100.025 42.427 55.113 1.00 18.52  ? 34  SER C N     1 
ATOM   2683 C CA    . SER E 3 34  ? -101.421 42.388 55.558 1.00 23.11  ? 34  SER C CA    1 
ATOM   2684 C C     . SER E 3 34  ? -101.605 41.125 56.405 1.00 25.15  ? 34  SER C C     1 
ATOM   2685 O O     . SER E 3 34  ? -100.779 40.213 56.346 1.00 19.22  ? 34  SER C O     1 
ATOM   2686 C CB    . SER E 3 34  ? -102.369 42.353 54.359 1.00 22.64  ? 34  SER C CB    1 
ATOM   2687 O OG    . SER E 3 34  ? -101.951 41.392 53.405 1.00 23.16  ? 34  SER C OG    1 
ATOM   2688 N N     . SER E 3 35  ? -102.682 41.057 57.185 1.00 25.04  ? 35  SER C N     1 
ATOM   2689 C CA    . SER E 3 35  ? -102.912 39.893 58.044 1.00 19.18  ? 35  SER C CA    1 
ATOM   2690 C C     . SER E 3 35  ? -103.306 38.590 57.340 1.00 29.06  ? 35  SER C C     1 
ATOM   2691 O O     . SER E 3 35  ? -103.571 38.562 56.136 1.00 31.35  ? 35  SER C O     1 
ATOM   2692 C CB    . SER E 3 35  ? -103.960 40.224 59.105 1.00 29.89  ? 35  SER C CB    1 
ATOM   2693 O OG    . SER E 3 35  ? -103.739 39.461 60.279 1.00 29.73  ? 35  SER C OG    1 
ATOM   2694 N N     . ASN E 3 36  ? -103.337 37.511 58.116 1.00 32.02  ? 36  ASN C N     1 
ATOM   2695 C CA    . ASN E 3 36  ? -103.676 36.180 57.624 1.00 30.47  ? 36  ASN C CA    1 
ATOM   2696 C C     . ASN E 3 36  ? -102.552 35.522 56.834 1.00 24.96  ? 36  ASN C C     1 
ATOM   2697 O O     . ASN E 3 36  ? -101.441 36.039 56.788 1.00 39.75  ? 36  ASN C O     1 
ATOM   2698 C CB    . ASN E 3 36  ? -104.950 36.224 56.791 1.00 35.55  ? 36  ASN C CB    1 
ATOM   2699 C CG    . ASN E 3 36  ? -106.134 35.686 57.547 1.00 43.51  ? 36  ASN C CG    1 
ATOM   2700 O OD1   . ASN E 3 36  ? -106.165 34.513 57.904 1.00 46.40  ? 36  ASN C OD1   1 
ATOM   2701 N ND2   . ASN E 3 36  ? -107.111 36.544 57.814 1.00 62.93  ? 36  ASN C ND2   1 
ATOM   2702 N N     . SER E 3 37  ? -102.843 34.380 56.216 1.00 22.44  ? 37  SER C N     1 
ATOM   2703 C CA    . SER E 3 37  ? -101.835 33.637 55.467 1.00 21.51  ? 37  SER C CA    1 
ATOM   2704 C C     . SER E 3 37  ? -100.864 34.516 54.704 1.00 21.22  ? 37  SER C C     1 
ATOM   2705 O O     . SER E 3 37  ? -101.250 35.289 53.829 1.00 28.09  ? 37  SER C O     1 
ATOM   2706 C CB    . SER E 3 37  ? -102.490 32.653 54.498 1.00 14.52  ? 37  SER C CB    1 
ATOM   2707 O OG    . SER E 3 37  ? -103.675 32.118 55.053 1.00 49.08  ? 37  SER C OG    1 
ATOM   2708 N N     . ARG E 3 38  ? -99.593  34.387 55.066 1.00 16.00  ? 38  ARG C N     1 
ATOM   2709 C CA    . ARG E 3 38  ? -98.508  35.122 54.435 1.00 15.66  ? 38  ARG C CA    1 
ATOM   2710 C C     . ARG E 3 38  ? -98.618  34.859 52.929 1.00 20.70  ? 38  ARG C C     1 
ATOM   2711 O O     . ARG E 3 38  ? -98.405  35.748 52.109 1.00 30.12  ? 38  ARG C O     1 
ATOM   2712 C CB    . ARG E 3 38  ? -97.179  34.597 55.003 1.00 12.83  ? 38  ARG C CB    1 
ATOM   2713 C CG    . ARG E 3 38  ? -95.880  35.175 54.452 1.00 12.91  ? 38  ARG C CG    1 
ATOM   2714 C CD    . ARG E 3 38  ? -95.918  36.675 54.243 1.00 14.39  ? 38  ARG C CD    1 
ATOM   2715 N NE    . ARG E 3 38  ? -95.877  36.981 52.814 1.00 40.25  ? 38  ARG C NE    1 
ATOM   2716 C CZ    . ARG E 3 38  ? -94.789  37.375 52.163 1.00 37.22  ? 38  ARG C CZ    1 
ATOM   2717 N NH1   . ARG E 3 38  ? -93.644  37.513 52.814 1.00 53.28  ? 38  ARG C NH1   1 
ATOM   2718 N NH2   . ARG E 3 38  ? -94.842  37.622 50.860 1.00 37.27  ? 38  ARG C NH2   1 
ATOM   2719 N N     . SER E 3 39  ? -98.987  33.628 52.586 1.00 22.94  ? 39  SER C N     1 
ATOM   2720 C CA    . SER E 3 39  ? -99.138  33.197 51.198 1.00 17.45  ? 39  SER C CA    1 
ATOM   2721 C C     . SER E 3 39  ? -100.091 34.065 50.371 1.00 20.79  ? 39  SER C C     1 
ATOM   2722 O O     . SER E 3 39  ? -99.936  34.180 49.152 1.00 30.95  ? 39  SER C O     1 
ATOM   2723 C CB    . SER E 3 39  ? -99.625  31.747 51.166 1.00 10.32  ? 39  SER C CB    1 
ATOM   2724 O OG    . SER E 3 39  ? -100.953 31.658 51.662 1.00 25.53  ? 39  SER C OG    1 
ATOM   2725 N N     . GLN E 3 40  ? -101.077 34.668 51.023 1.00 14.57  ? 40  GLN C N     1 
ATOM   2726 C CA    . GLN E 3 40  ? -102.040 35.501 50.315 1.00 17.37  ? 40  GLN C CA    1 
ATOM   2727 C C     . GLN E 3 40  ? -101.981 36.959 50.725 1.00 22.74  ? 40  GLN C C     1 
ATOM   2728 O O     . GLN E 3 40  ? -102.897 37.725 50.429 1.00 25.72  ? 40  GLN C O     1 
ATOM   2729 C CB    . GLN E 3 40  ? -103.452 35.013 50.584 1.00 6.91   ? 40  GLN C CB    1 
ATOM   2730 C CG    . GLN E 3 40  ? -103.663 33.546 50.398 1.00 22.93  ? 40  GLN C CG    1 
ATOM   2731 C CD    . GLN E 3 40  ? -105.092 33.174 50.689 1.00 27.49  ? 40  GLN C CD    1 
ATOM   2732 O OE1   . GLN E 3 40  ? -105.693 33.691 51.636 1.00 29.44  ? 40  GLN C OE1   1 
ATOM   2733 N NE2   . GLN E 3 40  ? -105.655 32.285 49.876 1.00 28.89  ? 40  GLN C NE2   1 
ATOM   2734 N N     . ALA E 3 41  ? -100.906 37.358 51.385 1.00 23.53  ? 41  ALA C N     1 
ATOM   2735 C CA    . ALA E 3 41  ? -100.818 38.721 51.873 1.00 16.72  ? 41  ALA C CA    1 
ATOM   2736 C C     . ALA E 3 41  ? -100.272 39.768 50.927 1.00 20.28  ? 41  ALA C C     1 
ATOM   2737 O O     . ALA E 3 41  ? -99.553  39.461 49.979 1.00 21.14  ? 41  ALA C O     1 
ATOM   2738 C CB    . ALA E 3 41  ? -100.012 38.734 53.153 1.00 23.13  ? 41  ALA C CB    1 
ATOM   2739 N N     . TYR E 3 42  ? -100.642 41.014 51.200 1.00 14.80  ? 42  TYR C N     1 
ATOM   2740 C CA    . TYR E 3 42  ? -100.148 42.150 50.442 1.00 13.99  ? 42  TYR C CA    1 
ATOM   2741 C C     . TYR E 3 42  ? -98.803  42.469 51.084 1.00 16.40  ? 42  TYR C C     1 
ATOM   2742 O O     . TYR E 3 42  ? -98.631  42.308 52.295 1.00 19.62  ? 42  TYR C O     1 
ATOM   2743 C CB    . TYR E 3 42  ? -101.057 43.357 50.618 1.00 10.21  ? 42  TYR C CB    1 
ATOM   2744 C CG    . TYR E 3 42  ? -102.296 43.336 49.773 1.00 25.33  ? 42  TYR C CG    1 
ATOM   2745 C CD1   . TYR E 3 42  ? -103.324 42.438 50.041 1.00 13.62  ? 42  TYR C CD1   1 
ATOM   2746 C CD2   . TYR E 3 42  ? -102.462 44.244 48.726 1.00 21.71  ? 42  TYR C CD2   1 
ATOM   2747 C CE1   . TYR E 3 42  ? -104.488 42.448 49.296 1.00 11.29  ? 42  TYR C CE1   1 
ATOM   2748 C CE2   . TYR E 3 42  ? -103.624 44.262 47.975 1.00 20.03  ? 42  TYR C CE2   1 
ATOM   2749 C CZ    . TYR E 3 42  ? -104.635 43.362 48.268 1.00 27.13  ? 42  TYR C CZ    1 
ATOM   2750 O OH    . TYR E 3 42  ? -105.809 43.389 47.553 1.00 35.44  ? 42  TYR C OH    1 
ATOM   2751 N N     . LYS E 3 43  ? -97.853  42.928 50.286 1.00 16.53  ? 43  LYS C N     1 
ATOM   2752 C CA    . LYS E 3 43  ? -96.544  43.254 50.823 1.00 20.22  ? 43  LYS C CA    1 
ATOM   2753 C C     . LYS E 3 43  ? -96.096  44.632 50.358 1.00 19.68  ? 43  LYS C C     1 
ATOM   2754 O O     . LYS E 3 43  ? -96.348  45.033 49.222 1.00 26.67  ? 43  LYS C O     1 
ATOM   2755 C CB    . LYS E 3 43  ? -95.534  42.189 50.388 1.00 14.42  ? 43  LYS C CB    1 
ATOM   2756 C CG    . LYS E 3 43  ? -94.094  42.462 50.772 1.00 18.67  ? 43  LYS C CG    1 
ATOM   2757 C CD    . LYS E 3 43  ? -93.294  41.173 50.751 1.00 19.60  ? 43  LYS C CD    1 
ATOM   2758 C CE    . LYS E 3 43  ? -91.815  41.437 50.539 1.00 25.58  ? 43  LYS C CE    1 
ATOM   2759 N NZ    . LYS E 3 43  ? -91.206  40.410 49.642 1.00 47.19  ? 43  LYS C NZ    1 
ATOM   2760 N N     . VAL E 3 44  ? -95.452  45.365 51.254 1.00 19.44  ? 44  VAL C N     1 
ATOM   2761 C CA    . VAL E 3 44  ? -94.939  46.687 50.934 1.00 18.98  ? 44  VAL C CA    1 
ATOM   2762 C C     . VAL E 3 44  ? -93.569  46.786 51.579 1.00 23.79  ? 44  VAL C C     1 
ATOM   2763 O O     . VAL E 3 44  ? -93.406  46.446 52.750 1.00 34.63  ? 44  VAL C O     1 
ATOM   2764 C CB    . VAL E 3 44  ? -95.832  47.812 51.512 1.00 13.01  ? 44  VAL C CB    1 
ATOM   2765 C CG1   . VAL E 3 44  ? -95.184  49.167 51.271 1.00 15.17  ? 44  VAL C CG1   1 
ATOM   2766 C CG2   . VAL E 3 44  ? -97.198  47.769 50.870 1.00 12.03  ? 44  VAL C CG2   1 
ATOM   2767 N N     . THR E 3 45  ? -92.576  47.213 50.813 1.00 18.61  ? 45  THR C N     1 
ATOM   2768 C CA    . THR E 3 45  ? -91.244  47.375 51.371 1.00 22.39  ? 45  THR C CA    1 
ATOM   2769 C C     . THR E 3 45  ? -90.734  48.742 50.971 1.00 24.53  ? 45  THR C C     1 
ATOM   2770 O O     . THR E 3 45  ? -91.163  49.310 49.964 1.00 21.60  ? 45  THR C O     1 
ATOM   2771 C CB    . THR E 3 45  ? -90.275  46.304 50.886 1.00 6.48   ? 45  THR C CB    1 
ATOM   2772 O OG1   . THR E 3 45  ? -89.935  46.551 49.520 1.00 25.42  ? 45  THR C OG1   1 
ATOM   2773 C CG2   . THR E 3 45  ? -90.899  44.938 51.034 1.00 22.59  ? 45  THR C CG2   1 
ATOM   2774 N N     . CYS E 3 46  ? -89.822  49.274 51.770 1.00 19.01  ? 46  CYS C N     1 
ATOM   2775 C CA    . CYS E 3 46  ? -89.290  50.593 51.506 1.00 20.60  ? 46  CYS C CA    1 
ATOM   2776 C C     . CYS E 3 46  ? -87.905  50.782 52.101 1.00 23.84  ? 46  CYS C C     1 
ATOM   2777 O O     . CYS E 3 46  ? -87.601  50.257 53.169 1.00 22.34  ? 46  CYS C O     1 
ATOM   2778 C CB    . CYS E 3 46  ? -90.238  51.638 52.081 1.00 15.92  ? 46  CYS C CB    1 
ATOM   2779 S SG    . CYS E 3 46  ? -89.585  53.300 52.013 1.00 23.17  ? 46  CYS C SG    1 
ATOM   2780 N N     . SER E 3 47  ? -87.066  51.536 51.402 1.00 23.24  ? 47  SER C N     1 
ATOM   2781 C CA    . SER E 3 47  ? -85.717  51.801 51.874 1.00 16.32  ? 47  SER C CA    1 
ATOM   2782 C C     . SER E 3 47  ? -85.139  53.040 51.205 1.00 15.93  ? 47  SER C C     1 
ATOM   2783 O O     . SER E 3 47  ? -85.540  53.406 50.103 1.00 34.20  ? 47  SER C O     1 
ATOM   2784 C CB    . SER E 3 47  ? -84.818  50.596 51.600 1.00 7.69   ? 47  SER C CB    1 
ATOM   2785 O OG    . SER E 3 47  ? -84.742  50.312 50.216 1.00 25.83  ? 47  SER C OG    1 
ATOM   2786 N N     . VAL E 3 48  ? -84.220  53.701 51.897 1.00 18.35  ? 48  VAL C N     1 
ATOM   2787 C CA    . VAL E 3 48  ? -83.553  54.885 51.371 1.00 22.14  ? 48  VAL C CA    1 
ATOM   2788 C C     . VAL E 3 48  ? -82.075  54.638 51.513 1.00 19.84  ? 48  VAL C C     1 
ATOM   2789 O O     . VAL E 3 48  ? -81.640  53.940 52.418 1.00 30.72  ? 48  VAL C O     1 
ATOM   2790 C CB    . VAL E 3 48  ? -83.854  56.169 52.159 1.00 13.64  ? 48  VAL C CB    1 
ATOM   2791 C CG1   . VAL E 3 48  ? -84.078  57.307 51.183 1.00 19.04  ? 48  VAL C CG1   1 
ATOM   2792 C CG2   . VAL E 3 48  ? -85.051  55.980 53.057 1.00 30.98  ? 48  VAL C CG2   1 
ATOM   2793 N N     . ARG E 3 49  ? -81.299  55.219 50.622 1.00 21.94  ? 49  ARG C N     1 
ATOM   2794 C CA    . ARG E 3 49  ? -79.868  55.047 50.670 1.00 20.78  ? 49  ARG C CA    1 
ATOM   2795 C C     . ARG E 3 49  ? -79.275  56.219 49.923 1.00 29.08  ? 49  ARG C C     1 
ATOM   2796 O O     . ARG E 3 49  ? -79.953  56.861 49.122 1.00 32.54  ? 49  ARG C O     1 
ATOM   2797 C CB    . ARG E 3 49  ? -79.478  53.734 49.989 1.00 8.40   ? 49  ARG C CB    1 
ATOM   2798 C CG    . ARG E 3 49  ? -79.859  53.682 48.527 1.00 47.75  ? 49  ARG C CG    1 
ATOM   2799 C CD    . ARG E 3 49  ? -79.027  52.670 47.756 1.00 69.75  ? 49  ARG C CD    1 
ATOM   2800 N NE    . ARG E 3 49  ? -79.527  52.458 46.396 1.00 82.28  ? 49  ARG C NE    1 
ATOM   2801 C CZ    . ARG E 3 49  ? -80.787  52.155 46.095 0.00 87.48  ? 49  ARG C CZ    1 
ATOM   2802 N NH1   . ARG E 3 49  ? -81.693  52.025 47.055 0.00 91.73  ? 49  ARG C NH1   1 
ATOM   2803 N NH2   . ARG E 3 49  ? -81.142  51.979 44.830 0.00 91.73  ? 49  ARG C NH2   1 
ATOM   2804 N N     . GLN E 3 50  ? -78.018  56.518 50.209 1.00 30.57  ? 50  GLN C N     1 
ATOM   2805 C CA    . GLN E 3 50  ? -77.334  57.597 49.524 1.00 25.04  ? 50  GLN C CA    1 
ATOM   2806 C C     . GLN E 3 50  ? -76.730  56.897 48.309 1.00 28.96  ? 50  GLN C C     1 
ATOM   2807 O O     . GLN E 3 50  ? -75.722  56.208 48.429 1.00 37.96  ? 50  GLN C O     1 
ATOM   2808 C CB    . GLN E 3 50  ? -76.246  58.165 50.431 1.00 13.78  ? 50  GLN C CB    1 
ATOM   2809 C CG    . GLN E 3 50  ? -75.608  59.435 49.923 1.00 33.56  ? 50  GLN C CG    1 
ATOM   2810 C CD    . GLN E 3 50  ? -76.293  60.676 50.437 1.00 35.11  ? 50  GLN C CD    1 
ATOM   2811 O OE1   . GLN E 3 50  ? -76.963  60.655 51.476 1.00 50.72  ? 50  GLN C OE1   1 
ATOM   2812 N NE2   . GLN E 3 50  ? -76.131  61.772 49.710 1.00 51.14  ? 50  GLN C NE2   1 
ATOM   2813 N N     . SER E 3 51  ? -77.366  57.049 47.149 1.00 28.97  ? 51  SER C N     1 
ATOM   2814 C CA    . SER E 3 51  ? -76.903  56.392 45.926 1.00 35.13  ? 51  SER C CA    1 
ATOM   2815 C C     . SER E 3 51  ? -75.636  57.004 45.347 1.00 43.21  ? 51  SER C C     1 
ATOM   2816 O O     . SER E 3 51  ? -74.865  56.328 44.660 1.00 55.75  ? 51  SER C O     1 
ATOM   2817 C CB    . SER E 3 51  ? -78.006  56.409 44.863 1.00 29.95  ? 51  SER C CB    1 
ATOM   2818 O OG    . SER E 3 51  ? -78.528  57.713 44.685 1.00 51.02  ? 51  SER C OG    1 
ATOM   2819 N N     . SER E 3 52  ? -75.432  58.287 45.618 1.00 37.72  ? 52  SER C N     1 
ATOM   2820 C CA    . SER E 3 52  ? -74.263  58.999 45.132 1.00 33.22  ? 52  SER C CA    1 
ATOM   2821 C C     . SER E 3 52  ? -73.996  60.159 46.077 1.00 38.51  ? 52  SER C C     1 
ATOM   2822 O O     . SER E 3 52  ? -74.746  60.380 47.029 1.00 43.86  ? 52  SER C O     1 
ATOM   2823 C CB    . SER E 3 52  ? -74.505  59.500 43.700 1.00 33.63  ? 52  SER C CB    1 
ATOM   2824 O OG    . SER E 3 52  ? -75.000  60.828 43.675 1.00 48.98  ? 52  SER C OG    1 
ATOM   2825 N N     . ALA E 3 53  ? -72.927  60.902 45.831 1.00 39.68  ? 53  ALA C N     1 
ATOM   2826 C CA    . ALA E 3 53  ? -72.613  62.019 46.705 1.00 43.96  ? 53  ALA C CA    1 
ATOM   2827 C C     . ALA E 3 53  ? -73.729  63.061 46.712 1.00 43.99  ? 53  ALA C C     1 
ATOM   2828 O O     . ALA E 3 53  ? -73.984  63.694 47.732 1.00 48.52  ? 53  ALA C O     1 
ATOM   2829 C CB    . ALA E 3 53  ? -71.303  62.657 46.277 1.00 40.48  ? 53  ALA C CB    1 
ATOM   2830 N N     . GLN E 3 54  ? -74.406  63.212 45.577 1.00 44.07  ? 54  GLN C N     1 
ATOM   2831 C CA    . GLN E 3 54  ? -75.473  64.197 45.431 1.00 33.36  ? 54  GLN C CA    1 
ATOM   2832 C C     . GLN E 3 54  ? -76.897  63.691 45.604 1.00 34.91  ? 54  GLN C C     1 
ATOM   2833 O O     . GLN E 3 54  ? -77.803  64.481 45.874 1.00 31.31  ? 54  GLN C O     1 
ATOM   2834 C CB    . GLN E 3 54  ? -75.376  64.845 44.056 1.00 51.12  ? 54  GLN C CB    1 
ATOM   2835 C CG    . GLN E 3 54  ? -73.969  65.211 43.644 1.00 81.38  ? 54  GLN C CG    1 
ATOM   2836 C CD    . GLN E 3 54  ? -73.792  66.707 43.488 1.00 94.68  ? 54  GLN C CD    1 
ATOM   2837 O OE1   . GLN E 3 54  ? -74.532  67.355 42.741 1.00 100.00 ? 54  GLN C OE1   1 
ATOM   2838 N NE2   . GLN E 3 54  ? -72.815  67.269 44.196 1.00 97.14  ? 54  GLN C NE2   1 
ATOM   2839 N N     . ASN E 3 55  ? -77.100  62.385 45.459 1.00 31.61  ? 55  ASN C N     1 
ATOM   2840 C CA    . ASN E 3 55  ? -78.443  61.823 45.541 1.00 25.71  ? 55  ASN C CA    1 
ATOM   2841 C C     . ASN E 3 55  ? -78.780  60.831 46.637 1.00 24.88  ? 55  ASN C C     1 
ATOM   2842 O O     . ASN E 3 55  ? -77.956  60.021 47.059 1.00 32.70  ? 55  ASN C O     1 
ATOM   2843 C CB    . ASN E 3 55  ? -78.801  61.145 44.216 1.00 35.14  ? 55  ASN C CB    1 
ATOM   2844 C CG    . ASN E 3 55  ? -78.768  62.091 43.047 1.00 29.14  ? 55  ASN C CG    1 
ATOM   2845 O OD1   . ASN E 3 55  ? -79.367  63.167 43.087 1.00 51.53  ? 55  ASN C OD1   1 
ATOM   2846 N ND2   . ASN E 3 55  ? -78.072  61.694 41.987 1.00 47.19  ? 55  ASN C ND2   1 
ATOM   2847 N N     . ARG E 3 56  ? -80.028  60.903 47.076 1.00 20.81  ? 56  ARG C N     1 
ATOM   2848 C CA    . ARG E 3 56  ? -80.560  59.971 48.052 1.00 24.10  ? 56  ARG C CA    1 
ATOM   2849 C C     . ARG E 3 56  ? -81.569  59.222 47.181 1.00 20.77  ? 56  ARG C C     1 
ATOM   2850 O O     . ARG E 3 56  ? -82.183  59.813 46.295 1.00 24.14  ? 56  ARG C O     1 
ATOM   2851 C CB    . ARG E 3 56  ? -81.246  60.709 49.199 1.00 13.14  ? 56  ARG C CB    1 
ATOM   2852 C CG    . ARG E 3 56  ? -80.337  60.892 50.393 1.00 18.60  ? 56  ARG C CG    1 
ATOM   2853 C CD    . ARG E 3 56  ? -80.991  61.725 51.463 1.00 28.90  ? 56  ARG C CD    1 
ATOM   2854 N NE    . ARG E 3 56  ? -82.064  61.003 52.137 1.00 45.90  ? 56  ARG C NE    1 
ATOM   2855 C CZ    . ARG E 3 56  ? -83.346  61.356 52.090 1.00 53.80  ? 56  ARG C CZ    1 
ATOM   2856 N NH1   . ARG E 3 56  ? -83.723  62.425 51.396 1.00 36.23  ? 56  ARG C NH1   1 
ATOM   2857 N NH2   . ARG E 3 56  ? -84.253  60.646 52.749 1.00 55.96  ? 56  ARG C NH2   1 
ATOM   2858 N N     . LYS E 3 57  ? -81.729  57.927 47.404 1.00 20.69  ? 57  LYS C N     1 
ATOM   2859 C CA    . LYS E 3 57  ? -82.632  57.151 46.576 1.00 12.62  ? 57  LYS C CA    1 
ATOM   2860 C C     . LYS E 3 57  ? -83.593  56.292 47.383 1.00 22.04  ? 57  LYS C C     1 
ATOM   2861 O O     . LYS E 3 57  ? -83.192  55.586 48.309 1.00 27.62  ? 57  LYS C O     1 
ATOM   2862 C CB    . LYS E 3 57  ? -81.799  56.274 45.648 1.00 15.40  ? 57  LYS C CB    1 
ATOM   2863 C CG    . LYS E 3 57  ? -82.572  55.558 44.562 1.00 26.62  ? 57  LYS C CG    1 
ATOM   2864 C CD    . LYS E 3 57  ? -81.696  55.432 43.333 1.00 35.94  ? 57  LYS C CD    1 
ATOM   2865 C CE    . LYS E 3 57  ? -81.779  54.050 42.724 1.00 49.74  ? 57  LYS C CE    1 
ATOM   2866 N NZ    . LYS E 3 57  ? -80.798  53.926 41.607 1.00 68.93  ? 57  LYS C NZ    1 
ATOM   2867 N N     . TYR E 3 58  ? -84.870  56.359 47.028 1.00 18.94  ? 58  TYR C N     1 
ATOM   2868 C CA    . TYR E 3 58  ? -85.883  55.567 47.709 1.00 20.64  ? 58  TYR C CA    1 
ATOM   2869 C C     . TYR E 3 58  ? -86.248  54.399 46.817 1.00 20.65  ? 58  TYR C C     1 
ATOM   2870 O O     . TYR E 3 58  ? -86.290  54.533 45.593 1.00 30.41  ? 58  TYR C O     1 
ATOM   2871 C CB    . TYR E 3 58  ? -87.149  56.381 47.954 1.00 10.93  ? 58  TYR C CB    1 
ATOM   2872 C CG    . TYR E 3 58  ? -87.037  57.428 49.026 1.00 19.47  ? 58  TYR C CG    1 
ATOM   2873 C CD1   . TYR E 3 58  ? -86.528  58.695 48.741 1.00 17.60  ? 58  TYR C CD1   1 
ATOM   2874 C CD2   . TYR E 3 58  ? -87.491  57.176 50.312 1.00 18.47  ? 58  TYR C CD2   1 
ATOM   2875 C CE1   . TYR E 3 58  ? -86.482  59.685 49.717 1.00 21.05  ? 58  TYR C CE1   1 
ATOM   2876 C CE2   . TYR E 3 58  ? -87.449  58.161 51.295 1.00 19.00  ? 58  TYR C CE2   1 
ATOM   2877 C CZ    . TYR E 3 58  ? -86.948  59.408 50.992 1.00 17.29  ? 58  TYR C CZ    1 
ATOM   2878 O OH    . TYR E 3 58  ? -86.934  60.380 51.963 1.00 36.18  ? 58  TYR C OH    1 
ATOM   2879 N N     . THR E 3 59  ? -86.506  53.253 47.433 1.00 17.79  ? 59  THR C N     1 
ATOM   2880 C CA    . THR E 3 59  ? -86.919  52.072 46.695 1.00 19.96  ? 59  THR C CA    1 
ATOM   2881 C C     . THR E 3 59  ? -88.145  51.481 47.378 1.00 19.62  ? 59  THR C C     1 
ATOM   2882 O O     . THR E 3 59  ? -88.044  50.881 48.448 1.00 31.57  ? 59  THR C O     1 
ATOM   2883 C CB    . THR E 3 59  ? -85.821  51.031 46.656 1.00 22.32  ? 59  THR C CB    1 
ATOM   2884 O OG1   . THR E 3 59  ? -84.673  51.578 45.996 1.00 24.55  ? 59  THR C OG1   1 
ATOM   2885 C CG2   . THR E 3 59  ? -86.299  49.813 45.907 1.00 12.54  ? 59  THR C CG2   1 
ATOM   2886 N N     . ILE E 3 60  ? -89.303  51.686 46.758 1.00 15.51  ? 60  ILE C N     1 
ATOM   2887 C CA    . ILE E 3 60  ? -90.580  51.206 47.270 1.00 16.04  ? 60  ILE C CA    1 
ATOM   2888 C C     . ILE E 3 60  ? -91.014  50.026 46.419 1.00 23.82  ? 60  ILE C C     1 
ATOM   2889 O O     . ILE E 3 60  ? -90.887  50.068 45.196 1.00 29.98  ? 60  ILE C O     1 
ATOM   2890 C CB    . ILE E 3 60  ? -91.700  52.269 47.139 1.00 19.36  ? 60  ILE C CB    1 
ATOM   2891 C CG1   . ILE E 3 60  ? -91.169  53.685 47.426 1.00 11.12  ? 60  ILE C CG1   1 
ATOM   2892 C CG2   . ILE E 3 60  ? -92.849  51.891 48.033 1.00 16.61  ? 60  ILE C CG2   1 
ATOM   2893 C CD1   . ILE E 3 60  ? -90.526  53.839 48.751 1.00 27.90  ? 60  ILE C CD1   1 
ATOM   2894 N N     . LYS E 3 61  ? -91.524  48.978 47.059 1.00 22.82  ? 61  LYS C N     1 
ATOM   2895 C CA    . LYS E 3 61  ? -92.000  47.800 46.339 1.00 12.69  ? 61  LYS C CA    1 
ATOM   2896 C C     . LYS E 3 61  ? -93.331  47.380 46.939 1.00 16.03  ? 61  LYS C C     1 
ATOM   2897 O O     . LYS E 3 61  ? -93.509  47.391 48.158 1.00 32.13  ? 61  LYS C O     1 
ATOM   2898 C CB    . LYS E 3 61  ? -90.997  46.649 46.447 1.00 12.55  ? 61  LYS C CB    1 
ATOM   2899 C CG    . LYS E 3 61  ? -90.016  46.557 45.277 1.00 25.60  ? 61  LYS C CG    1 
ATOM   2900 C CD    . LYS E 3 61  ? -88.656  46.013 45.714 1.00 24.59  ? 61  LYS C CD    1 
ATOM   2901 C CE    . LYS E 3 61  ? -87.914  45.331 44.567 1.00 38.58  ? 61  LYS C CE    1 
ATOM   2902 N NZ    . LYS E 3 61  ? -87.355  43.988 44.940 1.00 61.33  ? 61  LYS C NZ    1 
ATOM   2903 N N     . VAL E 3 62  ? -94.274  47.030 46.078 1.00 16.61  ? 62  VAL C N     1 
ATOM   2904 C CA    . VAL E 3 62  ? -95.587  46.599 46.530 1.00 14.52  ? 62  VAL C CA    1 
ATOM   2905 C C     . VAL E 3 62  ? -96.013  45.347 45.775 1.00 15.29  ? 62  VAL C C     1 
ATOM   2906 O O     . VAL E 3 62  ? -95.699  45.187 44.596 1.00 17.36  ? 62  VAL C O     1 
ATOM   2907 C CB    . VAL E 3 62  ? -96.636  47.682 46.294 1.00 15.50  ? 62  VAL C CB    1 
ATOM   2908 C CG1   . VAL E 3 62  ? -98.002  47.167 46.700 1.00 8.76   ? 62  VAL C CG1   1 
ATOM   2909 C CG2   . VAL E 3 62  ? -96.277  48.921 47.080 1.00 20.88  ? 62  VAL C CG2   1 
ATOM   2910 N N     . GLU E 3 63  ? -96.717  44.455 46.462 1.00 16.64  ? 63  GLU C N     1 
ATOM   2911 C CA    . GLU E 3 63  ? -97.193  43.226 45.848 1.00 17.94  ? 63  GLU C CA    1 
ATOM   2912 C C     . GLU E 3 63  ? -98.685  43.101 46.093 1.00 23.71  ? 63  GLU C C     1 
ATOM   2913 O O     . GLU E 3 63  ? -99.133  43.142 47.236 1.00 33.53  ? 63  GLU C O     1 
ATOM   2914 C CB    . GLU E 3 63  ? -96.487  42.016 46.452 1.00 9.65   ? 63  GLU C CB    1 
ATOM   2915 C CG    . GLU E 3 63  ? -95.152  41.685 45.815 1.00 29.52  ? 63  GLU C CG    1 
ATOM   2916 C CD    . GLU E 3 63  ? -94.393  40.614 46.576 1.00 29.26  ? 63  GLU C CD    1 
ATOM   2917 O OE1   . GLU E 3 63  ? -95.053  39.810 47.269 1.00 31.19  ? 63  GLU C OE1   1 
ATOM   2918 O OE2   . GLU E 3 63  ? -93.144  40.577 46.481 1.00 38.63  ? 63  GLU C OE2   1 
ATOM   2919 N N     . VAL E 3 64  ? -99.456  42.977 45.022 1.00 22.56  ? 64  VAL C N     1 
ATOM   2920 C CA    . VAL E 3 64  ? -100.892 42.810 45.161 1.00 21.32  ? 64  VAL C CA    1 
ATOM   2921 C C     . VAL E 3 64  ? -101.183 41.386 44.726 1.00 23.75  ? 64  VAL C C     1 
ATOM   2922 O O     . VAL E 3 64  ? -100.947 41.006 43.579 1.00 25.35  ? 64  VAL C O     1 
ATOM   2923 C CB    . VAL E 3 64  ? -101.659 43.799 44.295 1.00 12.70  ? 64  VAL C CB    1 
ATOM   2924 C CG1   . VAL E 3 64  ? -103.154 43.609 44.494 1.00 15.74  ? 64  VAL C CG1   1 
ATOM   2925 C CG2   . VAL E 3 64  ? -101.250 45.211 44.673 1.00 18.40  ? 64  VAL C CG2   1 
ATOM   2926 N N     . PRO E 3 65  ? -101.683 40.566 45.654 1.00 24.48  ? 65  PRO C N     1 
ATOM   2927 C CA    . PRO E 3 65  ? -101.985 39.175 45.341 1.00 22.16  ? 65  PRO C CA    1 
ATOM   2928 C C     . PRO E 3 65  ? -103.411 38.955 44.883 1.00 21.94  ? 65  PRO C C     1 
ATOM   2929 O O     . PRO E 3 65  ? -104.316 39.712 45.243 1.00 22.77  ? 65  PRO C O     1 
ATOM   2930 C CB    . PRO E 3 65  ? -101.734 38.481 46.662 1.00 22.75  ? 65  PRO C CB    1 
ATOM   2931 C CG    . PRO E 3 65  ? -102.269 39.497 47.662 1.00 12.52  ? 65  PRO C CG    1 
ATOM   2932 C CD    . PRO E 3 65  ? -102.001 40.872 47.060 1.00 22.50  ? 65  PRO C CD    1 
ATOM   2933 N N     . LYS E 3 66  ? -103.592 37.907 44.085 1.00 23.47  ? 66  LYS C N     1 
ATOM   2934 C CA    . LYS E 3 66  ? -104.904 37.501 43.603 1.00 22.35  ? 66  LYS C CA    1 
ATOM   2935 C C     . LYS E 3 66  ? -105.176 36.253 44.434 1.00 26.87  ? 66  LYS C C     1 
ATOM   2936 O O     . LYS E 3 66  ? -104.627 35.179 44.171 1.00 25.00  ? 66  LYS C O     1 
ATOM   2937 C CB    . LYS E 3 66  ? -104.858 37.137 42.121 1.00 24.62  ? 66  LYS C CB    1 
ATOM   2938 C CG    . LYS E 3 66  ? -106.142 36.502 41.618 1.00 19.43  ? 66  LYS C CG    1 
ATOM   2939 C CD    . LYS E 3 66  ? -107.227 37.541 41.465 1.00 18.36  ? 66  LYS C CD    1 
ATOM   2940 C CE    . LYS E 3 66  ? -108.601 36.917 41.488 1.00 8.09   ? 66  LYS C CE    1 
ATOM   2941 N NZ    . LYS E 3 66  ? -109.659 37.940 41.270 1.00 31.43  ? 66  LYS C NZ    1 
ATOM   2942 N N     . VAL E 3 67  ? -106.003 36.414 45.457 1.00 23.57  ? 67  VAL C N     1 
ATOM   2943 C CA    . VAL E 3 67  ? -106.332 35.327 46.365 1.00 25.42  ? 67  VAL C CA    1 
ATOM   2944 C C     . VAL E 3 67  ? -107.037 34.154 45.712 1.00 22.64  ? 67  VAL C C     1 
ATOM   2945 O O     . VAL E 3 67  ? -107.968 34.323 44.924 1.00 38.13  ? 67  VAL C O     1 
ATOM   2946 C CB    . VAL E 3 67  ? -107.195 35.835 47.515 1.00 13.57  ? 67  VAL C CB    1 
ATOM   2947 C CG1   . VAL E 3 67  ? -107.401 34.736 48.521 1.00 36.11  ? 67  VAL C CG1   1 
ATOM   2948 C CG2   . VAL E 3 67  ? -106.518 37.033 48.163 1.00 20.62  ? 67  VAL C CG2   1 
ATOM   2949 N N     . ALA E 3 68  ? -106.585 32.956 46.055 1.00 29.47  ? 68  ALA C N     1 
ATOM   2950 C CA    . ALA E 3 68  ? -107.162 31.740 45.508 1.00 32.93  ? 68  ALA C CA    1 
ATOM   2951 C C     . ALA E 3 68  ? -106.836 30.537 46.386 1.00 34.64  ? 68  ALA C C     1 
ATOM   2952 O O     . ALA E 3 68  ? -105.906 30.578 47.197 1.00 37.99  ? 68  ALA C O     1 
ATOM   2953 C CB    . ALA E 3 68  ? -106.643 31.515 44.098 1.00 30.35  ? 68  ALA C CB    1 
ATOM   2954 N N     . THR E 3 69  ? -107.616 29.473 46.220 1.00 33.79  ? 69  THR C N     1 
ATOM   2955 C CA    . THR E 3 69  ? -107.421 28.239 46.972 1.00 28.99  ? 69  THR C CA    1 
ATOM   2956 C C     . THR E 3 69  ? -106.885 27.167 46.041 1.00 29.58  ? 69  THR C C     1 
ATOM   2957 O O     . THR E 3 69  ? -107.546 26.780 45.082 1.00 53.19  ? 69  THR C O     1 
ATOM   2958 C CB    . THR E 3 69  ? -108.730 27.716 47.564 1.00 21.88  ? 69  THR C CB    1 
ATOM   2959 O OG1   . THR E 3 69  ? -109.332 28.727 48.383 1.00 46.33  ? 69  THR C OG1   1 
ATOM   2960 C CG2   . THR E 3 69  ? -108.460 26.473 48.398 1.00 40.13  ? 69  THR C CG2   1 
ATOM   2961 N N     . GLN E 3 70  ? -105.681 26.690 46.321 1.00 38.26  ? 70  GLN C N     1 
ATOM   2962 C CA    . GLN E 3 70  ? -105.077 25.663 45.491 1.00 31.10  ? 70  GLN C CA    1 
ATOM   2963 C C     . GLN E 3 70  ? -105.416 24.301 46.057 1.00 37.56  ? 70  GLN C C     1 
ATOM   2964 O O     . GLN E 3 70  ? -105.381 24.107 47.270 1.00 50.28  ? 70  GLN C O     1 
ATOM   2965 C CB    . GLN E 3 70  ? -103.566 25.830 45.456 1.00 23.67  ? 70  GLN C CB    1 
ATOM   2966 C CG    . GLN E 3 70  ? -102.839 24.572 45.066 1.00 26.87  ? 70  GLN C CG    1 
ATOM   2967 C CD    . GLN E 3 70  ? -101.343 24.719 45.186 1.00 44.69  ? 70  GLN C CD    1 
ATOM   2968 O OE1   . GLN E 3 70  ? -100.748 24.328 46.190 1.00 63.00  ? 70  GLN C OE1   1 
ATOM   2969 N NE2   . GLN E 3 70  ? -100.722 25.289 44.159 1.00 51.47  ? 70  GLN C NE2   1 
ATOM   2970 N N     . THR E 3 71  ? -105.761 23.364 45.181 1.00 47.49  ? 71  THR C N     1 
ATOM   2971 C CA    . THR E 3 71  ? -106.084 22.009 45.611 1.00 41.94  ? 71  THR C CA    1 
ATOM   2972 C C     . THR E 3 71  ? -105.233 21.006 44.848 1.00 40.62  ? 71  THR C C     1 
ATOM   2973 O O     . THR E 3 71  ? -105.176 21.022 43.621 1.00 40.68  ? 71  THR C O     1 
ATOM   2974 C CB    . THR E 3 71  ? -107.559 21.664 45.385 1.00 28.70  ? 71  THR C CB    1 
ATOM   2975 O OG1   . THR E 3 71  ? -108.387 22.474 46.233 1.00 40.02  ? 71  THR C OG1   1 
ATOM   2976 C CG2   . THR E 3 71  ? -107.795 20.209 45.715 1.00 27.70  ? 71  THR C CG2   1 
ATOM   2977 N N     . VAL E 3 72  ? -104.566 20.133 45.588 1.00 48.95  ? 72  VAL C N     1 
ATOM   2978 C CA    . VAL E 3 72  ? -103.709 19.133 44.982 1.00 51.52  ? 72  VAL C CA    1 
ATOM   2979 C C     . VAL E 3 72  ? -103.750 17.864 45.814 1.00 55.41  ? 72  VAL C C     1 
ATOM   2980 O O     . VAL E 3 72  ? -103.417 17.873 46.999 1.00 68.18  ? 72  VAL C O     1 
ATOM   2981 C CB    . VAL E 3 72  ? -102.264 19.646 44.891 1.00 48.06  ? 72  VAL C CB    1 
ATOM   2982 C CG1   . VAL E 3 72  ? -101.297 18.482 44.798 1.00 50.30  ? 72  VAL C CG1   1 
ATOM   2983 C CG2   . VAL E 3 72  ? -102.126 20.558 43.690 1.00 46.66  ? 72  VAL C CG2   1 
ATOM   2984 N N     . GLY E 3 73  ? -104.159 16.770 45.188 1.00 48.78  ? 73  GLY C N     1 
ATOM   2985 C CA    . GLY E 3 73  ? -104.238 15.520 45.913 1.00 47.30  ? 73  GLY C CA    1 
ATOM   2986 C C     . GLY E 3 73  ? -105.346 15.609 46.941 1.00 40.53  ? 73  GLY C C     1 
ATOM   2987 O O     . GLY E 3 73  ? -105.389 14.831 47.891 1.00 58.76  ? 73  GLY C O     1 
ATOM   2988 N N     . GLY E 3 74  ? -106.246 16.569 46.753 1.00 35.05  ? 74  GLY C N     1 
ATOM   2989 C CA    . GLY E 3 74  ? -107.352 16.728 47.679 1.00 33.60  ? 74  GLY C CA    1 
ATOM   2990 C C     . GLY E 3 74  ? -107.007 17.602 48.866 1.00 45.59  ? 74  GLY C C     1 
ATOM   2991 O O     . GLY E 3 74  ? -107.807 17.759 49.788 1.00 43.37  ? 74  GLY C O     1 
ATOM   2992 N N     . VAL E 3 75  ? -105.808 18.176 48.841 1.00 46.83  ? 75  VAL C N     1 
ATOM   2993 C CA    . VAL E 3 75  ? -105.351 19.040 49.917 1.00 41.09  ? 75  VAL C CA    1 
ATOM   2994 C C     . VAL E 3 75  ? -105.533 20.500 49.522 1.00 40.92  ? 75  VAL C C     1 
ATOM   2995 O O     . VAL E 3 75  ? -105.000 20.942 48.507 1.00 40.55  ? 75  VAL C O     1 
ATOM   2996 C CB    . VAL E 3 75  ? -103.860 18.789 50.226 1.00 36.60  ? 75  VAL C CB    1 
ATOM   2997 C CG1   . VAL E 3 75  ? -103.414 19.659 51.387 1.00 35.52  ? 75  VAL C CG1   1 
ATOM   2998 C CG2   . VAL E 3 75  ? -103.637 17.326 50.551 1.00 37.56  ? 75  VAL C CG2   1 
ATOM   2999 N N     . GLU E 3 76  ? -106.287 21.246 50.324 1.00 37.46  ? 76  GLU C N     1 
ATOM   3000 C CA    . GLU E 3 76  ? -106.517 22.659 50.041 1.00 42.49  ? 76  GLU C CA    1 
ATOM   3001 C C     . GLU E 3 76  ? -105.526 23.569 50.763 1.00 41.14  ? 76  GLU C C     1 
ATOM   3002 O O     . GLU E 3 76  ? -105.303 23.440 51.969 1.00 47.70  ? 76  GLU C O     1 
ATOM   3003 C CB    . GLU E 3 76  ? -107.934 23.055 50.434 1.00 40.62  ? 76  GLU C CB    1 
ATOM   3004 C CG    . GLU E 3 76  ? -108.994 22.573 49.482 1.00 59.78  ? 76  GLU C CG    1 
ATOM   3005 C CD    . GLU E 3 76  ? -110.372 23.034 49.893 1.00 71.32  ? 76  GLU C CD    1 
ATOM   3006 O OE1   . GLU E 3 76  ? -110.500 23.630 50.985 1.00 73.72  ? 76  GLU C OE1   1 
ATOM   3007 O OE2   . GLU E 3 76  ? -111.326 22.800 49.125 1.00 88.79  ? 76  GLU C OE2   1 
ATOM   3008 N N     . LEU E 3 77  ? -104.942 24.496 50.012 1.00 38.30  ? 77  LEU C N     1 
ATOM   3009 C CA    . LEU E 3 77  ? -103.977 25.443 50.551 1.00 22.25  ? 77  LEU C CA    1 
ATOM   3010 C C     . LEU E 3 77  ? -104.302 26.853 50.102 1.00 27.77  ? 77  LEU C C     1 
ATOM   3011 O O     . LEU E 3 77  ? -104.614 27.087 48.935 1.00 37.91  ? 77  LEU C O     1 
ATOM   3012 C CB    . LEU E 3 77  ? -102.577 25.114 50.057 1.00 20.00  ? 77  LEU C CB    1 
ATOM   3013 C CG    . LEU E 3 77  ? -101.881 23.883 50.608 1.00 22.99  ? 77  LEU C CG    1 
ATOM   3014 C CD1   . LEU E 3 77  ? -100.405 23.980 50.252 1.00 13.02  ? 77  LEU C CD1   1 
ATOM   3015 C CD2   . LEU E 3 77  ? -102.078 23.800 52.109 1.00 21.07  ? 77  LEU C CD2   1 
ATOM   3016 N N     . PRO E 3 78  ? -104.233 27.819 51.024 1.00 25.10  ? 78  PRO C N     1 
ATOM   3017 C CA    . PRO E 3 78  ? -104.525 29.197 50.635 1.00 19.18  ? 78  PRO C CA    1 
ATOM   3018 C C     . PRO E 3 78  ? -103.291 29.693 49.902 1.00 22.95  ? 78  PRO C C     1 
ATOM   3019 O O     . PRO E 3 78  ? -102.182 29.649 50.440 1.00 23.48  ? 78  PRO C O     1 
ATOM   3020 C CB    . PRO E 3 78  ? -104.717 29.921 51.963 1.00 11.77  ? 78  PRO C CB    1 
ATOM   3021 C CG    . PRO E 3 78  ? -104.641 28.867 53.026 1.00 20.93  ? 78  PRO C CG    1 
ATOM   3022 C CD    . PRO E 3 78  ? -103.889 27.722 52.445 1.00 23.84  ? 78  PRO C CD    1 
ATOM   3023 N N     . VAL E 3 79  ? -103.467 30.135 48.666 1.00 18.95  ? 79  VAL C N     1 
ATOM   3024 C CA    . VAL E 3 79  ? -102.332 30.620 47.904 1.00 20.74  ? 79  VAL C CA    1 
ATOM   3025 C C     . VAL E 3 79  ? -102.707 31.887 47.157 1.00 27.19  ? 79  VAL C C     1 
ATOM   3026 O O     . VAL E 3 79  ? -103.755 32.491 47.403 1.00 24.43  ? 79  VAL C O     1 
ATOM   3027 C CB    . VAL E 3 79  ? -101.852 29.556 46.882 1.00 21.05  ? 79  VAL C CB    1 
ATOM   3028 C CG1   . VAL E 3 79  ? -101.505 28.269 47.592 1.00 11.86  ? 79  VAL C CG1   1 
ATOM   3029 C CG2   . VAL E 3 79  ? -102.932 29.302 45.840 1.00 11.30  ? 79  VAL C CG2   1 
ATOM   3030 N N     . ALA E 3 80  ? -101.824 32.288 46.254 1.00 24.52  ? 80  ALA C N     1 
ATOM   3031 C CA    . ALA E 3 80  ? -102.054 33.446 45.415 1.00 24.56  ? 80  ALA C CA    1 
ATOM   3032 C C     . ALA E 3 80  ? -101.933 32.936 43.979 1.00 29.40  ? 80  ALA C C     1 
ATOM   3033 O O     . ALA E 3 80  ? -100.858 32.499 43.558 1.00 39.84  ? 80  ALA C O     1 
ATOM   3034 C CB    . ALA E 3 80  ? -101.008 34.510 45.696 1.00 18.21  ? 80  ALA C CB    1 
ATOM   3035 N N     . ALA E 3 81  ? -103.039 32.957 43.241 1.00 26.46  ? 81  ALA C N     1 
ATOM   3036 C CA    . ALA E 3 81  ? -103.028 32.502 41.855 1.00 21.20  ? 81  ALA C CA    1 
ATOM   3037 C C     . ALA E 3 81  ? -101.860 33.174 41.121 1.00 29.40  ? 81  ALA C C     1 
ATOM   3038 O O     . ALA E 3 81  ? -101.134 32.537 40.352 1.00 37.36  ? 81  ALA C O     1 
ATOM   3039 C CB    . ALA E 3 81  ? -104.339 32.854 41.193 1.00 19.26  ? 81  ALA C CB    1 
ATOM   3040 N N     . TRP E 3 82  ? -101.689 34.467 41.374 1.00 25.80  ? 82  TRP C N     1 
ATOM   3041 C CA    . TRP E 3 82  ? -100.609 35.249 40.783 1.00 21.92  ? 82  TRP C CA    1 
ATOM   3042 C C     . TRP E 3 82  ? -100.468 36.545 41.579 1.00 22.54  ? 82  TRP C C     1 
ATOM   3043 O O     . TRP E 3 82  ? -101.268 36.826 42.471 1.00 23.97  ? 82  TRP C O     1 
ATOM   3044 C CB    . TRP E 3 82  ? -100.892 35.558 39.301 1.00 23.46  ? 82  TRP C CB    1 
ATOM   3045 C CG    . TRP E 3 82  ? -102.311 35.966 39.000 1.00 25.77  ? 82  TRP C CG    1 
ATOM   3046 C CD1   . TRP E 3 82  ? -103.317 35.164 38.534 1.00 18.22  ? 82  TRP C CD1   1 
ATOM   3047 C CD2   . TRP E 3 82  ? -102.885 37.266 39.178 1.00 21.61  ? 82  TRP C CD2   1 
ATOM   3048 N NE1   . TRP E 3 82  ? -104.483 35.884 38.416 1.00 25.08  ? 82  TRP C NE1   1 
ATOM   3049 C CE2   . TRP E 3 82  ? -104.247 37.176 38.806 1.00 19.78  ? 82  TRP C CE2   1 
ATOM   3050 C CE3   . TRP E 3 82  ? -102.381 38.497 39.620 1.00 23.26  ? 82  TRP C CE3   1 
ATOM   3051 C CZ2   . TRP E 3 82  ? -105.113 38.270 38.861 1.00 15.06  ? 82  TRP C CZ2   1 
ATOM   3052 C CZ3   . TRP E 3 82  ? -103.243 39.589 39.676 1.00 24.01  ? 82  TRP C CZ3   1 
ATOM   3053 C CH2   . TRP E 3 82  ? -104.596 39.466 39.298 1.00 17.96  ? 82  TRP C CH2   1 
ATOM   3054 N N     . ARG E 3 83  ? -99.454  37.334 41.254 1.00 27.56  ? 83  ARG C N     1 
ATOM   3055 C CA    . ARG E 3 83  ? -99.223  38.584 41.959 1.00 18.94  ? 83  ARG C CA    1 
ATOM   3056 C C     . ARG E 3 83  ? -98.850  39.703 41.009 1.00 26.00  ? 83  ARG C C     1 
ATOM   3057 O O     . ARG E 3 83  ? -98.130  39.493 40.028 1.00 26.69  ? 83  ARG C O     1 
ATOM   3058 C CB    . ARG E 3 83  ? -98.084  38.416 42.965 1.00 14.60  ? 83  ARG C CB    1 
ATOM   3059 C CG    . ARG E 3 83  ? -98.510  37.843 44.291 1.00 29.08  ? 83  ARG C CG    1 
ATOM   3060 C CD    . ARG E 3 83  ? -97.322  37.500 45.186 1.00 16.08  ? 83  ARG C CD    1 
ATOM   3061 N NE    . ARG E 3 83  ? -97.790  36.880 46.425 1.00 34.15  ? 83  ARG C NE    1 
ATOM   3062 C CZ    . ARG E 3 83  ? -98.111  37.558 47.523 1.00 27.93  ? 83  ARG C CZ    1 
ATOM   3063 N NH1   . ARG E 3 83  ? -98.011  38.879 47.538 1.00 27.92  ? 83  ARG C NH1   1 
ATOM   3064 N NH2   . ARG E 3 83  ? -98.568  36.924 48.595 1.00 36.38  ? 83  ARG C NH2   1 
ATOM   3065 N N     . SER E 3 84  ? -99.345  40.896 41.311 1.00 29.07  ? 84  SER C N     1 
ATOM   3066 C CA    . SER E 3 84  ? -99.023  42.083 40.534 1.00 20.47  ? 84  SER C CA    1 
ATOM   3067 C C     . SER E 3 84  ? -97.829  42.698 41.278 1.00 21.08  ? 84  SER C C     1 
ATOM   3068 O O     . SER E 3 84  ? -97.845  42.786 42.508 1.00 24.75  ? 84  SER C O     1 
ATOM   3069 C CB    . SER E 3 84  ? -100.213 43.040 40.528 1.00 19.06  ? 84  SER C CB    1 
ATOM   3070 O OG    . SER E 3 84  ? -100.063 44.019 39.518 1.00 40.65  ? 84  SER C OG    1 
ATOM   3071 N N     . TYR E 3 85  ? -96.793  43.105 40.548 1.00 23.56  ? 85  TYR C N     1 
ATOM   3072 C CA    . TYR E 3 85  ? -95.600  43.669 41.183 1.00 18.22  ? 85  TYR C CA    1 
ATOM   3073 C C     . TYR E 3 85  ? -95.305  45.132 40.851 1.00 18.18  ? 85  TYR C C     1 
ATOM   3074 O O     . TYR E 3 85  ? -95.002  45.463 39.705 1.00 31.37  ? 85  TYR C O     1 
ATOM   3075 C CB    . TYR E 3 85  ? -94.364  42.835 40.814 1.00 20.84  ? 85  TYR C CB    1 
ATOM   3076 C CG    . TYR E 3 85  ? -94.376  41.407 41.315 1.00 19.69  ? 85  TYR C CG    1 
ATOM   3077 C CD1   . TYR E 3 85  ? -94.951  40.383 40.561 1.00 30.89  ? 85  TYR C CD1   1 
ATOM   3078 C CD2   . TYR E 3 85  ? -93.822  41.079 42.550 1.00 27.10  ? 85  TYR C CD2   1 
ATOM   3079 C CE1   . TYR E 3 85  ? -94.976  39.068 41.029 1.00 36.80  ? 85  TYR C CE1   1 
ATOM   3080 C CE2   . TYR E 3 85  ? -93.841  39.769 43.026 1.00 33.97  ? 85  TYR C CE2   1 
ATOM   3081 C CZ    . TYR E 3 85  ? -94.421  38.772 42.263 1.00 32.86  ? 85  TYR C CZ    1 
ATOM   3082 O OH    . TYR E 3 85  ? -94.455  37.485 42.747 1.00 40.99  ? 85  TYR C OH    1 
ATOM   3083 N N     . LEU E 3 86  ? -95.387  46.005 41.852 1.00 21.80  ? 86  LEU C N     1 
ATOM   3084 C CA    . LEU E 3 86  ? -95.074  47.414 41.640 1.00 22.98  ? 86  LEU C CA    1 
ATOM   3085 C C     . LEU E 3 86  ? -93.689  47.665 42.186 1.00 17.99  ? 86  LEU C C     1 
ATOM   3086 O O     . LEU E 3 86  ? -93.392  47.325 43.331 1.00 34.11  ? 86  LEU C O     1 
ATOM   3087 C CB    . LEU E 3 86  ? -96.038  48.353 42.367 1.00 21.01  ? 86  LEU C CB    1 
ATOM   3088 C CG    . LEU E 3 86  ? -95.528  49.809 42.356 1.00 28.78  ? 86  LEU C CG    1 
ATOM   3089 C CD1   . LEU E 3 86  ? -95.460  50.336 40.922 1.00 29.69  ? 86  LEU C CD1   1 
ATOM   3090 C CD2   . LEU E 3 86  ? -96.430  50.689 43.195 1.00 25.02  ? 86  LEU C CD2   1 
ATOM   3091 N N     . ASN E 3 87  ? -92.844  48.271 41.368 1.00 22.55  ? 87  ASN C N     1 
ATOM   3092 C CA    . ASN E 3 87  ? -91.490  48.571 41.787 1.00 23.92  ? 87  ASN C CA    1 
ATOM   3093 C C     . ASN E 3 87  ? -91.162  50.015 41.419 1.00 26.85  ? 87  ASN C C     1 
ATOM   3094 O O     . ASN E 3 87  ? -91.136  50.358 40.241 1.00 30.83  ? 87  ASN C O     1 
ATOM   3095 C CB    . ASN E 3 87  ? -90.514  47.618 41.091 1.00 20.82  ? 87  ASN C CB    1 
ATOM   3096 C CG    A ASN E 3 87  ? -90.713  46.156 41.505 0.55 30.38  ? 87  ASN C CG    1 
ATOM   3097 C CG    B ASN E 3 87  ? -89.102  47.789 41.574 0.45 27.63  ? 87  ASN C CG    1 
ATOM   3098 O OD1   A ASN E 3 87  ? -91.263  45.862 42.567 0.55 45.89  ? 87  ASN C OD1   1 
ATOM   3099 O OD1   B ASN E 3 87  ? -88.569  48.895 41.583 0.45 31.12  ? 87  ASN C OD1   1 
ATOM   3100 N ND2   A ASN E 3 87  ? -90.261  45.237 40.661 0.55 24.90  ? 87  ASN C ND2   1 
ATOM   3101 N ND2   B ASN E 3 87  ? -88.481  46.690 41.984 0.45 50.78  ? 87  ASN C ND2   1 
ATOM   3102 N N     . MET E 3 88  ? -90.945  50.876 42.410 1.00 18.16  ? 88  MET C N     1 
ATOM   3103 C CA    . MET E 3 88  ? -90.593  52.251 42.085 1.00 23.67  ? 88  MET C CA    1 
ATOM   3104 C C     . MET E 3 88  ? -89.332  52.747 42.762 1.00 19.76  ? 88  MET C C     1 
ATOM   3105 O O     . MET E 3 88  ? -89.026  52.382 43.891 1.00 26.05  ? 88  MET C O     1 
ATOM   3106 C CB    . MET E 3 88  ? -91.736  53.222 42.377 1.00 23.66  ? 88  MET C CB    1 
ATOM   3107 C CG    . MET E 3 88  ? -92.461  53.025 43.662 1.00 27.51  ? 88  MET C CG    1 
ATOM   3108 S SD    . MET E 3 88  ? -93.927  54.076 43.645 1.00 46.28  ? 88  MET C SD    1 
ATOM   3109 C CE    . MET E 3 88  ? -93.288  55.543 44.425 1.00 28.48  ? 88  MET C CE    1 
ATOM   3110 N N     . GLU E 3 89  ? -88.595  53.576 42.032 1.00 24.59  ? 89  GLU C N     1 
ATOM   3111 C CA    . GLU E 3 89  ? -87.356  54.164 42.508 1.00 14.49  ? 89  GLU C CA    1 
ATOM   3112 C C     . GLU E 3 89  ? -87.477  55.671 42.384 1.00 19.17  ? 89  GLU C C     1 
ATOM   3113 O O     . GLU E 3 89  ? -87.774  56.195 41.309 1.00 24.75  ? 89  GLU C O     1 
ATOM   3114 C CB    . GLU E 3 89  ? -86.182  53.691 41.662 1.00 15.97  ? 89  GLU C CB    1 
ATOM   3115 C CG    . GLU E 3 89  ? -85.852  52.227 41.829 1.00 47.97  ? 89  GLU C CG    1 
ATOM   3116 C CD    . GLU E 3 89  ? -84.390  51.948 41.573 1.00 67.34  ? 89  GLU C CD    1 
ATOM   3117 O OE1   . GLU E 3 89  ? -83.780  52.680 40.760 1.00 69.83  ? 89  GLU C OE1   1 
ATOM   3118 O OE2   . GLU E 3 89  ? -83.854  51.002 42.189 1.00 76.62  ? 89  GLU C OE2   1 
ATOM   3119 N N     . LEU E 3 90  ? -87.242  56.362 43.492 1.00 18.20  ? 90  LEU C N     1 
ATOM   3120 C CA    . LEU E 3 90  ? -87.327  57.810 43.525 1.00 17.65  ? 90  LEU C CA    1 
ATOM   3121 C C     . LEU E 3 90  ? -85.972  58.401 43.914 1.00 13.73  ? 90  LEU C C     1 
ATOM   3122 O O     . LEU E 3 90  ? -85.445  58.106 44.983 1.00 28.21  ? 90  LEU C O     1 
ATOM   3123 C CB    . LEU E 3 90  ? -88.396  58.224 44.531 1.00 5.94   ? 90  LEU C CB    1 
ATOM   3124 C CG    . LEU E 3 90  ? -88.609  59.718 44.690 1.00 21.56  ? 90  LEU C CG    1 
ATOM   3125 C CD1   . LEU E 3 90  ? -88.932  60.317 43.333 1.00 17.47  ? 90  LEU C CD1   1 
ATOM   3126 C CD2   . LEU E 3 90  ? -89.727  59.962 45.689 1.00 14.08  ? 90  LEU C CD2   1 
ATOM   3127 N N     . THR E 3 91  ? -85.404  59.222 43.037 1.00 25.72  ? 91  THR C N     1 
ATOM   3128 C CA    . THR E 3 91  ? -84.110  59.851 43.301 1.00 26.66  ? 91  THR C CA    1 
ATOM   3129 C C     . THR E 3 91  ? -84.284  61.324 43.621 1.00 23.66  ? 91  THR C C     1 
ATOM   3130 O O     . THR E 3 91  ? -84.878  62.067 42.845 1.00 30.81  ? 91  THR C O     1 
ATOM   3131 C CB    . THR E 3 91  ? -83.170  59.755 42.095 1.00 16.03  ? 91  THR C CB    1 
ATOM   3132 O OG1   . THR E 3 91  ? -82.805  58.390 41.881 1.00 33.32  ? 91  THR C OG1   1 
ATOM   3133 C CG2   . THR E 3 91  ? -81.914  60.558 42.345 1.00 26.35  ? 91  THR C CG2   1 
ATOM   3134 N N     . ILE E 3 92  ? -83.758  61.746 44.765 1.00 20.39  ? 92  ILE C N     1 
ATOM   3135 C CA    . ILE E 3 92  ? -83.858  63.137 45.174 1.00 19.63  ? 92  ILE C CA    1 
ATOM   3136 C C     . ILE E 3 92  ? -82.495  63.678 45.588 1.00 23.76  ? 92  ILE C C     1 
ATOM   3137 O O     . ILE E 3 92  ? -81.832  63.117 46.458 1.00 22.41  ? 92  ILE C O     1 
ATOM   3138 C CB    . ILE E 3 92  ? -84.838  63.306 46.356 1.00 7.48   ? 92  ILE C CB    1 
ATOM   3139 C CG1   . ILE E 3 92  ? -86.101  62.482 46.111 1.00 10.58  ? 92  ILE C CG1   1 
ATOM   3140 C CG2   . ILE E 3 92  ? -85.192  64.771 46.522 1.00 11.42  ? 92  ILE C CG2   1 
ATOM   3141 C CD1   . ILE E 3 92  ? -87.222  62.756 47.097 1.00 13.31  ? 92  ILE C CD1   1 
ATOM   3142 N N     . PRO E 3 93  ? -82.051  64.772 44.954 1.00 26.37  ? 93  PRO C N     1 
ATOM   3143 C CA    . PRO E 3 93  ? -80.757  65.393 45.266 1.00 22.16  ? 93  PRO C CA    1 
ATOM   3144 C C     . PRO E 3 93  ? -80.782  66.000 46.668 1.00 22.33  ? 93  PRO C C     1 
ATOM   3145 O O     . PRO E 3 93  ? -81.820  66.481 47.121 1.00 25.58  ? 93  PRO C O     1 
ATOM   3146 C CB    . PRO E 3 93  ? -80.593  66.464 44.190 1.00 17.57  ? 93  PRO C CB    1 
ATOM   3147 C CG    . PRO E 3 93  ? -81.667  66.189 43.172 1.00 24.52  ? 93  PRO C CG    1 
ATOM   3148 C CD    . PRO E 3 93  ? -82.765  65.489 43.888 1.00 25.69  ? 93  PRO C CD    1 
ATOM   3149 N N     . ILE E 3 94  ? -79.638  65.990 47.343 1.00 24.60  ? 94  ILE C N     1 
ATOM   3150 C CA    . ILE E 3 94  ? -79.535  66.515 48.704 1.00 21.91  ? 94  ILE C CA    1 
ATOM   3151 C C     . ILE E 3 94  ? -79.807  68.008 48.871 1.00 28.29  ? 94  ILE C C     1 
ATOM   3152 O O     . ILE E 3 94  ? -79.818  68.516 49.995 1.00 26.47  ? 94  ILE C O     1 
ATOM   3153 C CB    . ILE E 3 94  ? -78.159  66.220 49.287 1.00 23.80  ? 94  ILE C CB    1 
ATOM   3154 C CG1   . ILE E 3 94  ? -77.103  67.025 48.538 1.00 27.01  ? 94  ILE C CG1   1 
ATOM   3155 C CG2   . ILE E 3 94  ? -77.859  64.734 49.179 1.00 13.01  ? 94  ILE C CG2   1 
ATOM   3156 C CD1   . ILE E 3 94  ? -75.708  66.726 49.002 1.00 24.91  ? 94  ILE C CD1   1 
ATOM   3157 N N     . PHE E 3 95  ? -80.026  68.710 47.765 1.00 22.05  ? 95  PHE C N     1 
ATOM   3158 C CA    . PHE E 3 95  ? -80.307  70.137 47.828 1.00 22.60  ? 95  PHE C CA    1 
ATOM   3159 C C     . PHE E 3 95  ? -81.787  70.391 47.997 1.00 24.01  ? 95  PHE C C     1 
ATOM   3160 O O     . PHE E 3 95  ? -82.208  71.526 48.207 1.00 30.62  ? 95  PHE C O     1 
ATOM   3161 C CB    . PHE E 3 95  ? -79.829  70.818 46.559 1.00 19.36  ? 95  PHE C CB    1 
ATOM   3162 C CG    . PHE E 3 95  ? -78.414  70.528 46.241 1.00 28.60  ? 95  PHE C CG    1 
ATOM   3163 C CD1   . PHE E 3 95  ? -77.400  71.019 47.054 1.00 30.61  ? 95  PHE C CD1   1 
ATOM   3164 C CD2   . PHE E 3 95  ? -78.084  69.728 45.159 1.00 29.83  ? 95  PHE C CD2   1 
ATOM   3165 C CE1   . PHE E 3 95  ? -76.076  70.714 46.795 1.00 25.27  ? 95  PHE C CE1   1 
ATOM   3166 C CE2   . PHE E 3 95  ? -76.760  69.415 44.889 1.00 27.24  ? 95  PHE C CE2   1 
ATOM   3167 C CZ    . PHE E 3 95  ? -75.754  69.907 45.707 1.00 23.66  ? 95  PHE C CZ    1 
ATOM   3168 N N     . ALA E 3 96  ? -82.576  69.329 47.893 1.00 23.80  ? 96  ALA C N     1 
ATOM   3169 C CA    . ALA E 3 96  ? -84.015  69.453 48.027 1.00 19.80  ? 96  ALA C CA    1 
ATOM   3170 C C     . ALA E 3 96  ? -84.382  69.742 49.467 1.00 20.03  ? 96  ALA C C     1 
ATOM   3171 O O     . ALA E 3 96  ? -83.945  69.063 50.394 1.00 25.46  ? 96  ALA C O     1 
ATOM   3172 C CB    . ALA E 3 96  ? -84.703  68.179 47.560 1.00 17.32  ? 96  ALA C CB    1 
ATOM   3173 N N     . THR E 3 97  ? -85.187  70.773 49.641 1.00 23.00  ? 97  THR C N     1 
ATOM   3174 C CA    . THR E 3 97  ? -85.656  71.170 50.952 1.00 23.24  ? 97  THR C CA    1 
ATOM   3175 C C     . THR E 3 97  ? -86.949  70.409 51.213 1.00 31.31  ? 97  THR C C     1 
ATOM   3176 O O     . THR E 3 97  ? -87.421  69.667 50.353 1.00 38.89  ? 97  THR C O     1 
ATOM   3177 C CB    . THR E 3 97  ? -85.936  72.657 50.961 1.00 28.01  ? 97  THR C CB    1 
ATOM   3178 O OG1   . THR E 3 97  ? -87.080  72.937 50.138 1.00 37.72  ? 97  THR C OG1   1 
ATOM   3179 C CG2   . THR E 3 97  ? -84.746  73.391 50.396 1.00 22.45  ? 97  THR C CG2   1 
ATOM   3180 N N     . ASN E 3 98  ? -87.529  70.584 52.392 1.00 39.21  ? 98  ASN C N     1 
ATOM   3181 C CA    . ASN E 3 98  ? -88.765  69.882 52.694 1.00 32.05  ? 98  ASN C CA    1 
ATOM   3182 C C     . ASN E 3 98  ? -89.853  70.313 51.721 1.00 32.13  ? 98  ASN C C     1 
ATOM   3183 O O     . ASN E 3 98  ? -90.680  69.500 51.311 1.00 44.18  ? 98  ASN C O     1 
ATOM   3184 C CB    . ASN E 3 98  ? -89.192  70.151 54.135 1.00 36.11  ? 98  ASN C CB    1 
ATOM   3185 C CG    . ASN E 3 98  ? -88.377  69.356 55.140 1.00 41.00  ? 98  ASN C CG    1 
ATOM   3186 O OD1   . ASN E 3 98  ? -87.353  68.758 54.797 1.00 51.46  ? 98  ASN C OD1   1 
ATOM   3187 N ND2   . ASN E 3 98  ? -88.828  69.345 56.388 1.00 46.51  ? 98  ASN C ND2   1 
ATOM   3188 N N     . SER E 3 99  ? -89.843  71.588 51.338 1.00 30.11  ? 99  SER C N     1 
ATOM   3189 C CA    . SER E 3 99  ? -90.837  72.104 50.397 1.00 31.51  ? 99  SER C CA    1 
ATOM   3190 C C     . SER E 3 99  ? -90.688  71.397 49.060 1.00 30.35  ? 99  SER C C     1 
ATOM   3191 O O     . SER E 3 99  ? -91.677  70.950 48.474 1.00 33.95  ? 99  SER C O     1 
ATOM   3192 C CB    . SER E 3 99  ? -90.663  73.607 50.196 1.00 21.93  ? 99  SER C CB    1 
ATOM   3193 O OG    . SER E 3 99  ? -90.390  74.249 51.428 1.00 75.74  ? 99  SER C OG    1 
ATOM   3194 N N     . ASP E 3 100 ? -89.448  71.300 48.586 1.00 27.33  ? 100 ASP C N     1 
ATOM   3195 C CA    . ASP E 3 100 ? -89.162  70.629 47.323 1.00 17.27  ? 100 ASP C CA    1 
ATOM   3196 C C     . ASP E 3 100 ? -89.719  69.200 47.372 1.00 26.55  ? 100 ASP C C     1 
ATOM   3197 O O     . ASP E 3 100 ? -90.323  68.724 46.413 1.00 28.99  ? 100 ASP C O     1 
ATOM   3198 C CB    . ASP E 3 100 ? -87.646  70.577 47.074 1.00 27.59  ? 100 ASP C CB    1 
ATOM   3199 C CG    . ASP E 3 100 ? -87.041  71.946 46.771 1.00 28.47  ? 100 ASP C CG    1 
ATOM   3200 O OD1   . ASP E 3 100 ? -87.760  72.838 46.274 1.00 24.47  ? 100 ASP C OD1   1 
ATOM   3201 O OD2   . ASP E 3 100 ? -85.829  72.123 47.027 1.00 36.42  ? 100 ASP C OD2   1 
ATOM   3202 N N     . CYS E 3 101 ? -89.517  68.525 48.500 1.00 24.92  ? 101 CYS C N     1 
ATOM   3203 C CA    . CYS E 3 101 ? -89.981  67.155 48.669 1.00 21.83  ? 101 CYS C CA    1 
ATOM   3204 C C     . CYS E 3 101 ? -91.495  67.053 48.689 1.00 24.79  ? 101 CYS C C     1 
ATOM   3205 O O     . CYS E 3 101 ? -92.063  66.120 48.126 1.00 31.19  ? 101 CYS C O     1 
ATOM   3206 C CB    . CYS E 3 101 ? -89.403  66.571 49.952 1.00 16.51  ? 101 CYS C CB    1 
ATOM   3207 S SG    . CYS E 3 101 ? -87.642  66.264 49.801 1.00 25.42  ? 101 CYS C SG    1 
ATOM   3208 N N     . GLU E 3 102 ? -92.147  68.005 49.344 1.00 26.14  ? 102 GLU C N     1 
ATOM   3209 C CA    . GLU E 3 102 ? -93.602  68.011 49.409 1.00 25.52  ? 102 GLU C CA    1 
ATOM   3210 C C     . GLU E 3 102 ? -94.144  68.120 47.993 1.00 26.99  ? 102 GLU C C     1 
ATOM   3211 O O     . GLU E 3 102 ? -95.158  67.512 47.643 1.00 24.40  ? 102 GLU C O     1 
ATOM   3212 C CB    . GLU E 3 102 ? -94.084  69.195 50.237 1.00 22.27  ? 102 GLU C CB    1 
ATOM   3213 C CG    . GLU E 3 102 ? -94.159  68.898 51.714 1.00 54.51  ? 102 GLU C CG    1 
ATOM   3214 C CD    . GLU E 3 102 ? -94.224  70.149 52.550 1.00 59.08  ? 102 GLU C CD    1 
ATOM   3215 O OE1   . GLU E 3 102 ? -94.836  71.139 52.089 1.00 65.49  ? 102 GLU C OE1   1 
ATOM   3216 O OE2   . GLU E 3 102 ? -93.661  70.136 53.666 1.00 66.93  ? 102 GLU C OE2   1 
ATOM   3217 N N     . LEU E 3 103 ? -93.447  68.901 47.178 1.00 24.26  ? 103 LEU C N     1 
ATOM   3218 C CA    . LEU E 3 103 ? -93.834  69.095 45.792 1.00 22.68  ? 103 LEU C CA    1 
ATOM   3219 C C     . LEU E 3 103 ? -93.733  67.776 45.037 1.00 20.95  ? 103 LEU C C     1 
ATOM   3220 O O     . LEU E 3 103 ? -94.632  67.404 44.289 1.00 24.19  ? 103 LEU C O     1 
ATOM   3221 C CB    . LEU E 3 103 ? -92.925  70.129 45.143 1.00 19.63  ? 103 LEU C CB    1 
ATOM   3222 C CG    . LEU E 3 103 ? -93.420  70.592 43.783 1.00 25.24  ? 103 LEU C CG    1 
ATOM   3223 C CD1   . LEU E 3 103 ? -94.487  71.638 44.004 1.00 27.80  ? 103 LEU C CD1   1 
ATOM   3224 C CD2   . LEU E 3 103 ? -92.264  71.134 42.954 1.00 40.81  ? 103 LEU C CD2   1 
ATOM   3225 N N     . ILE E 3 104 ? -92.626  67.073 45.241 1.00 20.36  ? 104 ILE C N     1 
ATOM   3226 C CA    . ILE E 3 104 ? -92.412  65.789 44.593 1.00 17.59  ? 104 ILE C CA    1 
ATOM   3227 C C     . ILE E 3 104 ? -93.535  64.817 44.954 1.00 24.33  ? 104 ILE C C     1 
ATOM   3228 O O     . ILE E 3 104 ? -94.057  64.111 44.085 1.00 23.17  ? 104 ILE C O     1 
ATOM   3229 C CB    . ILE E 3 104 ? -91.073  65.182 45.020 1.00 16.04  ? 104 ILE C CB    1 
ATOM   3230 C CG1   . ILE E 3 104 ? -89.926  65.984 44.408 1.00 8.48   ? 104 ILE C CG1   1 
ATOM   3231 C CG2   . ILE E 3 104 ? -90.997  63.732 44.594 1.00 13.04  ? 104 ILE C CG2   1 
ATOM   3232 C CD1   . ILE E 3 104 ? -88.614  65.777 45.116 1.00 11.39  ? 104 ILE C CD1   1 
ATOM   3233 N N     . VAL E 3 105 ? -93.907  64.782 46.232 1.00 18.17  ? 105 VAL C N     1 
ATOM   3234 C CA    . VAL E 3 105 ? -94.971  63.889 46.687 1.00 18.44  ? 105 VAL C CA    1 
ATOM   3235 C C     . VAL E 3 105 ? -96.287  64.245 45.998 1.00 23.11  ? 105 VAL C C     1 
ATOM   3236 O O     . VAL E 3 105 ? -97.026  63.368 45.550 1.00 25.37  ? 105 VAL C O     1 
ATOM   3237 C CB    . VAL E 3 105 ? -95.155  63.964 48.221 1.00 14.20  ? 105 VAL C CB    1 
ATOM   3238 C CG1   . VAL E 3 105 ? -96.427  63.245 48.630 1.00 10.51  ? 105 VAL C CG1   1 
ATOM   3239 C CG2   . VAL E 3 105 ? -93.964  63.330 48.917 1.00 10.18  ? 105 VAL C CG2   1 
ATOM   3240 N N     . LYS E 3 106 ? -96.578  65.534 45.904 1.00 21.68  ? 106 LYS C N     1 
ATOM   3241 C CA    . LYS E 3 106 ? -97.799  65.966 45.244 1.00 18.36  ? 106 LYS C CA    1 
ATOM   3242 C C     . LYS E 3 106 ? -97.825  65.474 43.792 1.00 19.82  ? 106 LYS C C     1 
ATOM   3243 O O     . LYS E 3 106 ? -98.843  64.983 43.313 1.00 25.66  ? 106 LYS C O     1 
ATOM   3244 C CB    . LYS E 3 106 ? -97.896  67.488 45.280 1.00 14.04  ? 106 LYS C CB    1 
ATOM   3245 C CG    . LYS E 3 106 ? -98.204  68.044 46.658 1.00 20.75  ? 106 LYS C CG    1 
ATOM   3246 C CD    . LYS E 3 106 ? -98.986  69.338 46.563 1.00 40.98  ? 106 LYS C CD    1 
ATOM   3247 C CE    . LYS E 3 106 ? -99.256  69.919 47.937 1.00 62.19  ? 106 LYS C CE    1 
ATOM   3248 N NZ    . LYS E 3 106 ? -100.220 71.051 47.859 1.00 91.55  ? 106 LYS C NZ    1 
ATOM   3249 N N     . ALA E 3 107 ? -96.704  65.595 43.090 1.00 13.76  ? 107 ALA C N     1 
ATOM   3250 C CA    . ALA E 3 107 ? -96.649  65.147 41.703 1.00 18.90  ? 107 ALA C CA    1 
ATOM   3251 C C     . ALA E 3 107 ? -96.959  63.657 41.621 1.00 17.30  ? 107 ALA C C     1 
ATOM   3252 O O     . ALA E 3 107 ? -97.663  63.211 40.716 1.00 21.32  ? 107 ALA C O     1 
ATOM   3253 C CB    . ALA E 3 107 ? -95.280  65.429 41.111 1.00 6.22   ? 107 ALA C CB    1 
ATOM   3254 N N     . MET E 3 108 ? -96.441  62.889 42.574 1.00 16.27  ? 108 MET C N     1 
ATOM   3255 C CA    . MET E 3 108 ? -96.679  61.451 42.585 1.00 20.98  ? 108 MET C CA    1 
ATOM   3256 C C     . MET E 3 108 ? -98.164  61.185 42.779 1.00 22.95  ? 108 MET C C     1 
ATOM   3257 O O     . MET E 3 108 ? -98.766  60.356 42.087 1.00 23.22  ? 108 MET C O     1 
ATOM   3258 C CB    . MET E 3 108 ? -95.879  60.794 43.705 1.00 20.81  ? 108 MET C CB    1 
ATOM   3259 C CG    . MET E 3 108 ? -94.536  60.242 43.251 1.00 29.87  ? 108 MET C CG    1 
ATOM   3260 S SD    . MET E 3 108 ? -93.562  59.604 44.621 1.00 32.04  ? 108 MET C SD    1 
ATOM   3261 C CE    . MET E 3 108 ? -93.068  61.109 45.349 1.00 46.63  ? 108 MET C CE    1 
ATOM   3262 N N     . GLN E 3 109 ? -98.752  61.910 43.720 1.00 15.80  ? 109 GLN C N     1 
ATOM   3263 C CA    . GLN E 3 109 ? -100.170 61.772 44.013 1.00 15.76  ? 109 GLN C CA    1 
ATOM   3264 C C     . GLN E 3 109 ? -101.026 62.165 42.811 1.00 19.13  ? 109 GLN C C     1 
ATOM   3265 O O     . GLN E 3 109 ? -102.007 61.493 42.489 1.00 27.53  ? 109 GLN C O     1 
ATOM   3266 C CB    . GLN E 3 109 ? -100.534 62.641 45.215 1.00 5.53   ? 109 GLN C CB    1 
ATOM   3267 C CG    . GLN E 3 109 ? -99.844  62.220 46.496 1.00 13.92  ? 109 GLN C CG    1 
ATOM   3268 C CD    . GLN E 3 109 ? -100.149 63.142 47.651 1.00 23.94  ? 109 GLN C CD    1 
ATOM   3269 O OE1   . GLN E 3 109 ? -100.325 64.350 47.474 1.00 39.33  ? 109 GLN C OE1   1 
ATOM   3270 N NE2   . GLN E 3 109 ? -100.213 62.576 48.848 1.00 22.40  ? 109 GLN C NE2   1 
ATOM   3271 N N     . GLY E 3 110 ? -100.645 63.253 42.147 1.00 20.22  ? 110 GLY C N     1 
ATOM   3272 C CA    . GLY E 3 110 ? -101.392 63.714 40.990 1.00 20.44  ? 110 GLY C CA    1 
ATOM   3273 C C     . GLY E 3 110 ? -101.328 62.726 39.848 1.00 22.36  ? 110 GLY C C     1 
ATOM   3274 O O     . GLY E 3 110 ? -102.320 62.464 39.181 1.00 29.19  ? 110 GLY C O     1 
ATOM   3275 N N     . LEU E 3 111 ? -100.150 62.167 39.628 1.00 22.59  ? 111 LEU C N     1 
ATOM   3276 C CA    . LEU E 3 111 ? -99.959  61.201 38.568 1.00 23.55  ? 111 LEU C CA    1 
ATOM   3277 C C     . LEU E 3 111 ? -100.968 60.060 38.668 1.00 29.38  ? 111 LEU C C     1 
ATOM   3278 O O     . LEU E 3 111 ? -101.422 59.529 37.653 1.00 33.23  ? 111 LEU C O     1 
ATOM   3279 C CB    . LEU E 3 111 ? -98.540  60.638 38.649 1.00 22.55  ? 111 LEU C CB    1 
ATOM   3280 C CG    . LEU E 3 111 ? -98.210  59.461 37.739 1.00 14.69  ? 111 LEU C CG    1 
ATOM   3281 C CD1   . LEU E 3 111 ? -97.925  59.962 36.335 1.00 20.18  ? 111 LEU C CD1   1 
ATOM   3282 C CD2   . LEU E 3 111 ? -97.013  58.732 38.290 1.00 20.99  ? 111 LEU C CD2   1 
ATOM   3283 N N     . LEU E 3 112 ? -101.330 59.697 39.894 1.00 26.95  ? 112 LEU C N     1 
ATOM   3284 C CA    . LEU E 3 112 ? -102.249 58.584 40.106 1.00 25.65  ? 112 LEU C CA    1 
ATOM   3285 C C     . LEU E 3 112 ? -103.671 58.937 40.507 1.00 28.17  ? 112 LEU C C     1 
ATOM   3286 O O     . LEU E 3 112 ? -104.485 58.045 40.757 1.00 27.49  ? 112 LEU C O     1 
ATOM   3287 C CB    . LEU E 3 112 ? -101.665 57.632 41.146 1.00 13.31  ? 112 LEU C CB    1 
ATOM   3288 C CG    . LEU E 3 112 ? -100.294 57.085 40.767 1.00 21.01  ? 112 LEU C CG    1 
ATOM   3289 C CD1   . LEU E 3 112 ? -99.591  56.572 42.001 1.00 19.29  ? 112 LEU C CD1   1 
ATOM   3290 C CD2   . LEU E 3 112 ? -100.463 55.987 39.742 1.00 14.72  ? 112 LEU C CD2   1 
ATOM   3291 N N     . LYS E 3 113 ? -103.981 60.226 40.570 1.00 25.12  ? 113 LYS C N     1 
ATOM   3292 C CA    . LYS E 3 113 ? -105.329 60.643 40.946 1.00 25.00  ? 113 LYS C CA    1 
ATOM   3293 C C     . LYS E 3 113 ? -106.402 60.075 40.014 1.00 24.87  ? 113 LYS C C     1 
ATOM   3294 O O     . LYS E 3 113 ? -106.198 59.958 38.803 1.00 28.15  ? 113 LYS C O     1 
ATOM   3295 C CB    . LYS E 3 113 ? -105.432 62.173 40.966 1.00 18.02  ? 113 LYS C CB    1 
ATOM   3296 C CG    . LYS E 3 113 ? -106.864 62.693 41.044 1.00 25.12  ? 113 LYS C CG    1 
ATOM   3297 C CD    . LYS E 3 113 ? -106.970 64.012 41.794 1.00 40.97  ? 113 LYS C CD    1 
ATOM   3298 C CE    . LYS E 3 113 ? -108.322 64.681 41.549 1.00 59.00  ? 113 LYS C CE    1 
ATOM   3299 N NZ    . LYS E 3 113 ? -108.383 66.061 42.117 1.00 76.57  ? 113 LYS C NZ    1 
ATOM   3300 N N     . ASP E 3 114 ? -107.547 59.726 40.591 1.00 32.06  ? 114 ASP C N     1 
ATOM   3301 C CA    . ASP E 3 114 ? -108.667 59.189 39.825 1.00 25.93  ? 114 ASP C CA    1 
ATOM   3302 C C     . ASP E 3 114 ? -109.004 60.110 38.662 1.00 23.96  ? 114 ASP C C     1 
ATOM   3303 O O     . ASP E 3 114 ? -109.077 61.333 38.821 1.00 29.01  ? 114 ASP C O     1 
ATOM   3304 C CB    . ASP E 3 114 ? -109.904 59.056 40.712 1.00 29.92  ? 114 ASP C CB    1 
ATOM   3305 C CG    . ASP E 3 114 ? -110.134 57.645 41.183 1.00 40.71  ? 114 ASP C CG    1 
ATOM   3306 O OD1   . ASP E 3 114 ? -109.193 56.826 41.125 1.00 50.52  ? 114 ASP C OD1   1 
ATOM   3307 O OD2   . ASP E 3 114 ? -111.267 57.357 41.618 1.00 73.31  ? 114 ASP C OD2   1 
ATOM   3308 N N     . GLY E 3 115 ? -109.208 59.519 37.491 1.00 30.57  ? 115 GLY C N     1 
ATOM   3309 C CA    . GLY E 3 115 ? -109.556 60.308 36.325 1.00 23.10  ? 115 GLY C CA    1 
ATOM   3310 C C     . GLY E 3 115 ? -108.404 60.596 35.392 1.00 29.75  ? 115 GLY C C     1 
ATOM   3311 O O     . GLY E 3 115 ? -108.603 60.722 34.183 1.00 40.55  ? 115 GLY C O     1 
ATOM   3312 N N     . ASN E 3 116 ? -107.199 60.695 35.942 1.00 23.11  ? 116 ASN C N     1 
ATOM   3313 C CA    . ASN E 3 116 ? -106.032 60.983 35.130 1.00 17.18  ? 116 ASN C CA    1 
ATOM   3314 C C     . ASN E 3 116 ? -105.657 59.832 34.206 1.00 23.41  ? 116 ASN C C     1 
ATOM   3315 O O     . ASN E 3 116 ? -105.982 58.674 34.463 1.00 30.77  ? 116 ASN C O     1 
ATOM   3316 C CB    . ASN E 3 116 ? -104.872 61.384 36.031 1.00 31.07  ? 116 ASN C CB    1 
ATOM   3317 C CG    . ASN E 3 116 ? -105.069 62.764 36.621 1.00 29.01  ? 116 ASN C CG    1 
ATOM   3318 O OD1   . ASN E 3 116 ? -106.076 63.411 36.353 1.00 26.30  ? 116 ASN C OD1   1 
ATOM   3319 N ND2   . ASN E 3 116 ? -104.115 63.223 37.423 1.00 37.55  ? 116 ASN C ND2   1 
ATOM   3320 N N     . PRO E 3 117 ? -104.958 60.142 33.112 1.00 24.33  ? 117 PRO C N     1 
ATOM   3321 C CA    . PRO E 3 117 ? -104.540 59.142 32.127 1.00 16.07  ? 117 PRO C CA    1 
ATOM   3322 C C     . PRO E 3 117 ? -103.946 57.826 32.633 1.00 23.55  ? 117 PRO C C     1 
ATOM   3323 O O     . PRO E 3 117 ? -104.515 56.758 32.385 1.00 23.37  ? 117 PRO C O     1 
ATOM   3324 C CB    . PRO E 3 117 ? -103.568 59.909 31.235 1.00 24.14  ? 117 PRO C CB    1 
ATOM   3325 C CG    . PRO E 3 117 ? -104.029 61.326 31.334 1.00 16.77  ? 117 PRO C CG    1 
ATOM   3326 C CD    . PRO E 3 117 ? -104.494 61.496 32.752 1.00 12.67  ? 117 PRO C CD    1 
ATOM   3327 N N     . ILE E 3 118 ? -102.816 57.891 33.336 1.00 17.00  ? 118 ILE C N     1 
ATOM   3328 C CA    . ILE E 3 118 ? -102.170 56.670 33.805 1.00 21.20  ? 118 ILE C CA    1 
ATOM   3329 C C     . ILE E 3 118 ? -103.049 55.731 34.640 1.00 28.34  ? 118 ILE C C     1 
ATOM   3330 O O     . ILE E 3 118 ? -103.143 54.533 34.345 1.00 27.36  ? 118 ILE C O     1 
ATOM   3331 C CB    . ILE E 3 118 ? -100.866 56.980 34.574 1.00 25.40  ? 118 ILE C CB    1 
ATOM   3332 C CG1   . ILE E 3 118 ? -99.740  57.254 33.577 1.00 19.56  ? 118 ILE C CG1   1 
ATOM   3333 C CG2   . ILE E 3 118 ? -100.450 55.778 35.421 1.00 26.21  ? 118 ILE C CG2   1 
ATOM   3334 C CD1   . ILE E 3 118 ? -99.772  58.627 33.011 1.00 25.55  ? 118 ILE C CD1   1 
ATOM   3335 N N     . PRO E 3 119 ? -103.695 56.248 35.695 1.00 18.21  ? 119 PRO C N     1 
ATOM   3336 C CA    . PRO E 3 119 ? -104.531 55.332 36.480 1.00 19.55  ? 119 PRO C CA    1 
ATOM   3337 C C     . PRO E 3 119 ? -105.705 54.772 35.669 1.00 23.72  ? 119 PRO C C     1 
ATOM   3338 O O     . PRO E 3 119 ? -106.058 53.597 35.790 1.00 25.15  ? 119 PRO C O     1 
ATOM   3339 C CB    . PRO E 3 119 ? -104.978 56.173 37.682 1.00 8.66   ? 119 PRO C CB    1 
ATOM   3340 C CG    . PRO E 3 119 ? -104.755 57.581 37.289 1.00 16.62  ? 119 PRO C CG    1 
ATOM   3341 C CD    . PRO E 3 119 ? -103.685 57.617 36.237 1.00 23.76  ? 119 PRO C CD    1 
ATOM   3342 N N     . SER E 3 120 ? -106.296 55.612 34.829 1.00 24.48  ? 120 SER C N     1 
ATOM   3343 C CA    . SER E 3 120 ? -107.414 55.190 33.993 1.00 23.58  ? 120 SER C CA    1 
ATOM   3344 C C     . SER E 3 120 ? -107.008 54.038 33.087 1.00 25.20  ? 120 SER C C     1 
ATOM   3345 O O     . SER E 3 120 ? -107.721 53.040 32.974 1.00 32.82  ? 120 SER C O     1 
ATOM   3346 C CB    . SER E 3 120 ? -107.887 56.354 33.136 1.00 11.62  ? 120 SER C CB    1 
ATOM   3347 O OG    . SER E 3 120 ? -108.212 57.466 33.950 1.00 55.17  ? 120 SER C OG    1 
ATOM   3348 N N     . ALA E 3 121 ? -105.857 54.191 32.442 1.00 15.39  ? 121 ALA C N     1 
ATOM   3349 C CA    . ALA E 3 121 ? -105.339 53.174 31.542 1.00 19.11  ? 121 ALA C CA    1 
ATOM   3350 C C     . ALA E 3 121 ? -105.133 51.858 32.273 1.00 23.99  ? 121 ALA C C     1 
ATOM   3351 O O     . ALA E 3 121 ? -105.639 50.818 31.854 1.00 24.76  ? 121 ALA C O     1 
ATOM   3352 C CB    . ALA E 3 121 ? -104.024 53.642 30.936 1.00 8.41   ? 121 ALA C CB    1 
ATOM   3353 N N     . ILE E 3 122 ? -104.387 51.914 33.372 1.00 24.08  ? 122 ILE C N     1 
ATOM   3354 C CA    . ILE E 3 122 ? -104.088 50.726 34.163 1.00 18.92  ? 122 ILE C CA    1 
ATOM   3355 C C     . ILE E 3 122 ? -105.346 50.000 34.608 1.00 24.09  ? 122 ILE C C     1 
ATOM   3356 O O     . ILE E 3 122 ? -105.462 48.785 34.461 1.00 28.79  ? 122 ILE C O     1 
ATOM   3357 C CB    . ILE E 3 122 ? -103.280 51.088 35.425 1.00 20.32  ? 122 ILE C CB    1 
ATOM   3358 C CG1   . ILE E 3 122 ? -101.899 51.601 35.026 1.00 14.82  ? 122 ILE C CG1   1 
ATOM   3359 C CG2   . ILE E 3 122 ? -103.135 49.867 36.329 1.00 11.58  ? 122 ILE C CG2   1 
ATOM   3360 C CD1   . ILE E 3 122 ? -101.087 52.083 36.198 1.00 8.33   ? 122 ILE C CD1   1 
ATOM   3361 N N     . ALA E 3 123 ? -106.288 50.757 35.152 1.00 21.72  ? 123 ALA C N     1 
ATOM   3362 C CA    . ALA E 3 123 ? -107.529 50.189 35.655 1.00 19.98  ? 123 ALA C CA    1 
ATOM   3363 C C     . ALA E 3 123 ? -108.397 49.568 34.586 1.00 20.01  ? 123 ALA C C     1 
ATOM   3364 O O     . ALA E 3 123 ? -109.407 48.937 34.891 1.00 31.92  ? 123 ALA C O     1 
ATOM   3365 C CB    . ALA E 3 123 ? -108.313 51.252 36.382 1.00 13.27  ? 123 ALA C CB    1 
ATOM   3366 N N     . ALA E 3 124 ? -108.022 49.749 33.331 1.00 23.39  ? 124 ALA C N     1 
ATOM   3367 C CA    . ALA E 3 124 ? -108.828 49.203 32.255 1.00 19.60  ? 124 ALA C CA    1 
ATOM   3368 C C     . ALA E 3 124 ? -108.028 48.300 31.355 1.00 24.19  ? 124 ALA C C     1 
ATOM   3369 O O     . ALA E 3 124 ? -108.358 48.149 30.181 1.00 30.79  ? 124 ALA C O     1 
ATOM   3370 C CB    . ALA E 3 124 ? -109.429 50.321 31.448 1.00 2.00   ? 124 ALA C CB    1 
ATOM   3371 N N     . ASN E 3 125 ? -106.971 47.705 31.893 1.00 24.31  ? 125 ASN C N     1 
ATOM   3372 C CA    . ASN E 3 125 ? -106.149 46.813 31.091 1.00 26.66  ? 125 ASN C CA    1 
ATOM   3373 C C     . ASN E 3 125 ? -105.756 47.521 29.805 1.00 28.20  ? 125 ASN C C     1 
ATOM   3374 O O     . ASN E 3 125 ? -105.533 46.870 28.794 1.00 41.51  ? 125 ASN C O     1 
ATOM   3375 C CB    . ASN E 3 125 ? -106.949 45.572 30.711 1.00 27.39  ? 125 ASN C CB    1 
ATOM   3376 C CG    . ASN E 3 125 ? -106.796 44.453 31.700 1.00 34.52  ? 125 ASN C CG    1 
ATOM   3377 O OD1   . ASN E 3 125 ? -105.733 43.840 31.803 1.00 41.82  ? 125 ASN C OD1   1 
ATOM   3378 N ND2   . ASN E 3 125 ? -107.866 44.165 32.433 1.00 38.17  ? 125 ASN C ND2   1 
ATOM   3379 N N     . SER E 3 126 ? -105.674 48.846 29.834 1.00 33.18  ? 126 SER C N     1 
ATOM   3380 C CA    . SER E 3 126 ? -105.348 49.594 28.627 1.00 24.36  ? 126 SER C CA    1 
ATOM   3381 C C     . SER E 3 126 ? -104.032 50.348 28.652 1.00 24.34  ? 126 SER C C     1 
ATOM   3382 O O     . SER E 3 126 ? -103.364 50.444 29.681 1.00 33.09  ? 126 SER C O     1 
ATOM   3383 C CB    . SER E 3 126 ? -106.470 50.594 28.320 1.00 26.38  ? 126 SER C CB    1 
ATOM   3384 O OG    . SER E 3 126 ? -107.730 49.950 28.205 1.00 38.42  ? 126 SER C OG    1 
ATOM   3385 N N     . GLY E 3 127 ? -103.677 50.881 27.488 1.00 25.89  ? 127 GLY C N     1 
ATOM   3386 C CA    . GLY E 3 127 ? -102.477 51.680 27.344 1.00 18.96  ? 127 GLY C CA    1 
ATOM   3387 C C     . GLY E 3 127 ? -102.936 53.105 27.071 1.00 21.51  ? 127 GLY C C     1 
ATOM   3388 O O     . GLY E 3 127 ? -104.034 53.497 27.464 1.00 27.06  ? 127 GLY C O     1 
ATOM   3389 N N     . ILE E 3 128 ? -102.107 53.887 26.397 1.00 18.61  ? 128 ILE C N     1 
ATOM   3390 C CA    . ILE E 3 128 ? -102.466 55.261 26.072 1.00 22.48  ? 128 ILE C CA    1 
ATOM   3391 C C     . ILE E 3 128 ? -103.011 55.310 24.643 1.00 30.58  ? 128 ILE C C     1 
ATOM   3392 O O     . ILE E 3 128 ? -102.510 54.621 23.749 1.00 24.61  ? 128 ILE C O     1 
ATOM   3393 C CB    . ILE E 3 128 ? -101.238 56.186 26.181 1.00 24.48  ? 128 ILE C CB    1 
ATOM   3394 C CG1   . ILE E 3 128 ? -100.592 56.028 27.558 1.00 23.92  ? 128 ILE C CG1   1 
ATOM   3395 C CG2   . ILE E 3 128 ? -101.651 57.625 25.962 1.00 18.56  ? 128 ILE C CG2   1 
ATOM   3396 C CD1   . ILE E 3 128 ? -101.513 56.396 28.709 1.00 20.84  ? 128 ILE C CD1   1 
ATOM   3397 N N     . TYR E 3 129 ? -104.038 56.120 24.422 1.00 25.24  ? 129 TYR C N     1 
ATOM   3398 C CA    . TYR E 3 129 ? -104.616 56.229 23.089 1.00 29.30  ? 129 TYR C CA    1 
ATOM   3399 C C     . TYR E 3 129 ? -105.248 57.594 22.863 1.00 33.50  ? 129 TYR C C     1 
ATOM   3400 O O     . TYR E 3 129 ? -105.744 58.179 23.852 1.00 33.27  ? 129 TYR C O     1 
ATOM   3401 C CB    . TYR E 3 129 ? -105.660 55.132 22.885 1.00 22.44  ? 129 TYR C CB    1 
ATOM   3402 C CG    . TYR E 3 129 ? -106.744 55.138 23.931 1.00 24.21  ? 129 TYR C CG    1 
ATOM   3403 C CD1   . TYR E 3 129 ? -106.600 54.419 25.119 1.00 21.10  ? 129 TYR C CD1   1 
ATOM   3404 C CD2   . TYR E 3 129 ? -107.905 55.892 23.748 1.00 20.87  ? 129 TYR C CD2   1 
ATOM   3405 C CE1   . TYR E 3 129 ? -107.589 54.456 26.105 1.00 30.27  ? 129 TYR C CE1   1 
ATOM   3406 C CE2   . TYR E 3 129 ? -108.897 55.936 24.723 1.00 25.93  ? 129 TYR C CE2   1 
ATOM   3407 C CZ    . TYR E 3 129 ? -108.734 55.221 25.896 1.00 32.99  ? 129 TYR C CZ    1 
ATOM   3408 O OH    . TYR E 3 129 ? -109.712 55.286 26.861 1.00 51.02  ? 129 TYR C OH    1 
ATOM   3409 O OXT   . TYR E 3 129 ? -105.233 58.062 21.702 1.00 46.07  ? 129 TYR C OXT   1 
HETATM 3410 O O     . HOH F 4 .   ? -55.417  67.093 71.878 1.00 69.09  ? 85  HOH R O     1 
HETATM 3411 O O     . HOH G 4 .   ? -86.492  48.159 26.985 1.00 50.75  ? 86  HOH S O     1 
HETATM 3412 O O     . HOH H 4 .   ? -66.060  70.444 57.172 1.00 94.12  ? 130 HOH A O     1 
HETATM 3413 O O     . HOH H 4 .   ? -75.917  54.707 91.967 1.00 69.65  ? 131 HOH A O     1 
HETATM 3414 O O     . HOH H 4 .   ? -66.014  72.013 82.309 1.00 20.08  ? 132 HOH A O     1 
HETATM 3415 O O     . HOH H 4 .   ? -78.657  51.079 68.334 1.00 60.93  ? 133 HOH A O     1 
HETATM 3416 O O     . HOH H 4 .   ? -82.273  47.944 59.679 1.00 33.87  ? 134 HOH A O     1 
HETATM 3417 O O     . HOH H 4 .   ? -74.502  48.817 80.479 1.00 58.89  ? 135 HOH A O     1 
HETATM 3418 O O     . HOH H 4 .   ? -81.713  73.895 53.986 1.00 76.03  ? 136 HOH A O     1 
HETATM 3419 O O     . HOH H 4 .   ? -69.199  79.010 79.335 1.00 93.61  ? 137 HOH A O     1 
HETATM 3420 O O     . HOH H 4 .   ? -76.468  48.200 83.079 1.00 32.15  ? 138 HOH A O     1 
HETATM 3421 O O     . HOH H 4 .   ? -71.879  55.423 87.591 1.00 23.18  ? 139 HOH A O     1 
HETATM 3422 O O     . HOH H 4 .   ? -79.156  74.255 73.384 1.00 33.86  ? 140 HOH A O     1 
HETATM 3423 O O     . HOH H 4 .   ? -71.922  51.861 69.668 1.00 27.59  ? 141 HOH A O     1 
HETATM 3424 O O     . HOH H 4 .   ? -81.584  50.022 88.027 1.00 30.68  ? 142 HOH A O     1 
HETATM 3425 O O     . HOH H 4 .   ? -75.589  75.850 80.804 1.00 40.31  ? 143 HOH A O     1 
HETATM 3426 O O     . HOH H 4 .   ? -66.036  54.795 75.650 1.00 40.63  ? 144 HOH A O     1 
HETATM 3427 O O     . HOH H 4 .   ? -85.477  54.291 56.741 1.00 34.35  ? 145 HOH A O     1 
HETATM 3428 O O     . HOH H 4 .   ? -80.386  55.087 60.148 1.00 43.24  ? 146 HOH A O     1 
HETATM 3429 O O     . HOH H 4 .   ? -77.476  51.975 79.684 1.00 53.41  ? 147 HOH A O     1 
HETATM 3430 O O     . HOH H 4 .   ? -66.966  80.306 58.277 1.00 99.80  ? 148 HOH A O     1 
HETATM 3431 O O     . HOH H 4 .   ? -80.178  58.760 56.705 1.00 64.62  ? 149 HOH A O     1 
HETATM 3432 O O     . HOH H 4 .   ? -66.463  49.569 82.060 1.00 77.25  ? 150 HOH A O     1 
HETATM 3433 O O     . HOH H 4 .   ? -81.019  52.381 90.246 1.00 81.49  ? 151 HOH A O     1 
HETATM 3434 O O     . HOH H 4 .   ? -72.114  72.145 86.948 1.00 85.77  ? 152 HOH A O     1 
HETATM 3435 O O     . HOH H 4 .   ? -75.287  71.806 80.308 1.00 87.04  ? 153 HOH A O     1 
HETATM 3436 O O     . HOH I 4 .   ? -96.189  20.234 80.036 1.00 15.50  ? 130 HOH B O     1 
HETATM 3437 O O     . HOH I 4 .   ? -78.700  38.031 87.445 1.00 39.64  ? 131 HOH B O     1 
HETATM 3438 O O     . HOH I 4 .   ? -71.156  44.481 94.024 1.00 63.27  ? 132 HOH B O     1 
HETATM 3439 O O     . HOH I 4 .   ? -87.346  39.260 90.095 1.00 60.62  ? 133 HOH B O     1 
HETATM 3440 O O     . HOH I 4 .   ? -83.610  49.593 63.501 1.00 69.81  ? 134 HOH B O     1 
HETATM 3441 O O     . HOH I 4 .   ? -81.407  33.536 75.567 1.00 57.41  ? 135 HOH B O     1 
HETATM 3442 O O     . HOH I 4 .   ? -78.697  38.338 90.328 1.00 20.41  ? 136 HOH B O     1 
HETATM 3443 O O     . HOH I 4 .   ? -74.974  39.080 83.761 1.00 59.62  ? 137 HOH B O     1 
HETATM 3444 O O     . HOH I 4 .   ? -96.225  31.980 58.369 1.00 52.44  ? 138 HOH B O     1 
HETATM 3445 O O     . HOH I 4 .   ? -82.147  32.406 86.398 1.00 46.01  ? 139 HOH B O     1 
HETATM 3446 O O     . HOH I 4 .   ? -76.801  37.442 79.920 1.00 88.65  ? 140 HOH B O     1 
HETATM 3447 O O     . HOH I 4 .   ? -92.683  21.286 90.773 1.00 81.91  ? 141 HOH B O     1 
HETATM 3448 O O     . HOH I 4 .   ? -75.764  45.438 89.227 1.00 17.50  ? 142 HOH B O     1 
HETATM 3449 O O     . HOH I 4 .   ? -80.360  45.506 89.209 1.00 25.29  ? 143 HOH B O     1 
HETATM 3450 O O     . HOH I 4 .   ? -97.788  34.539 62.464 1.00 21.22  ? 144 HOH B O     1 
HETATM 3451 O O     . HOH I 4 .   ? -99.028  32.938 57.460 1.00 20.57  ? 145 HOH B O     1 
HETATM 3452 O O     . HOH I 4 .   ? -96.299  35.214 85.182 1.00 29.35  ? 146 HOH B O     1 
HETATM 3453 O O     . HOH I 4 .   ? -82.683  41.035 89.250 1.00 30.42  ? 147 HOH B O     1 
HETATM 3454 O O     . HOH I 4 .   ? -73.589  38.411 86.716 1.00 41.35  ? 148 HOH B O     1 
HETATM 3455 O O     . HOH I 4 .   ? -83.283  45.934 69.614 1.00 37.18  ? 149 HOH B O     1 
HETATM 3456 O O     . HOH I 4 .   ? -69.307  35.352 83.485 1.00 53.42  ? 150 HOH B O     1 
HETATM 3457 O O     . HOH I 4 .   ? -104.479 27.503 56.683 1.00 55.49  ? 151 HOH B O     1 
HETATM 3458 O O     . HOH I 4 .   ? -81.283  51.561 70.169 1.00 35.35  ? 152 HOH B O     1 
HETATM 3459 O O     . HOH I 4 .   ? -74.788  38.717 94.928 1.00 43.60  ? 153 HOH B O     1 
HETATM 3460 O O     . HOH I 4 .   ? -75.930  39.593 88.358 1.00 31.20  ? 154 HOH B O     1 
HETATM 3461 O O     . HOH I 4 .   ? -74.351  41.725 88.683 1.00 19.63  ? 155 HOH B O     1 
HETATM 3462 O O     . HOH I 4 .   ? -78.606  43.279 78.088 1.00 77.72  ? 156 HOH B O     1 
HETATM 3463 O O     . HOH I 4 .   ? -81.037  47.972 90.652 1.00 82.36  ? 157 HOH B O     1 
HETATM 3464 O O     . HOH I 4 .   ? -80.444  37.350 75.262 1.00 83.11  ? 158 HOH B O     1 
HETATM 3465 O O     . HOH I 4 .   ? -79.508  43.191 97.813 1.00 100.00 ? 159 HOH B O     1 
HETATM 3466 O O     . HOH I 4 .   ? -90.492  51.453 77.526 1.00 74.12  ? 160 HOH B O     1 
HETATM 3467 O O     . HOH I 4 .   ? -80.615  46.411 73.347 1.00 100.00 ? 161 HOH B O     1 
HETATM 3468 O O     . HOH I 4 .   ? -99.145  42.649 80.973 1.00 75.90  ? 162 HOH B O     1 
HETATM 3469 O O     . HOH I 4 .   ? -96.722  37.377 58.354 1.00 83.98  ? 163 HOH B O     1 
HETATM 3470 O O     . HOH I 4 .   ? -89.539  46.897 86.172 1.00 86.25  ? 164 HOH B O     1 
HETATM 3471 O O     . HOH I 4 .   ? -87.151  26.000 60.741 1.00 70.42  ? 165 HOH B O     1 
HETATM 3472 O O     . HOH J 4 .   ? -102.068 60.072 34.944 1.00 28.56  ? 130 HOH C O     1 
HETATM 3473 O O     . HOH J 4 .   ? -83.860  52.465 54.482 1.00 42.68  ? 131 HOH C O     1 
HETATM 3474 O O     . HOH J 4 .   ? -100.307 41.534 59.722 1.00 59.77  ? 132 HOH C O     1 
HETATM 3475 O O     . HOH J 4 .   ? -105.790 66.566 35.644 1.00 57.79  ? 133 HOH C O     1 
HETATM 3476 O O     . HOH J 4 .   ? -107.388 41.646 48.746 1.00 72.48  ? 134 HOH C O     1 
HETATM 3477 O O     . HOH J 4 .   ? -107.590 33.299 59.966 1.00 100.00 ? 135 HOH C O     1 
HETATM 3478 O O     . HOH J 4 .   ? -107.043 39.059 45.485 1.00 87.83  ? 136 HOH C O     1 
HETATM 3479 O O     . HOH J 4 .   ? -106.689 34.962 37.975 1.00 37.29  ? 137 HOH C O     1 
HETATM 3480 O O     . HOH J 4 .   ? -103.384 36.916 53.936 1.00 36.94  ? 138 HOH C O     1 
HETATM 3481 O O     . HOH J 4 .   ? -82.405  66.942 50.664 1.00 38.66  ? 139 HOH C O     1 
HETATM 3482 O O     . HOH J 4 .   ? -103.762 40.003 53.970 1.00 56.10  ? 140 HOH C O     1 
HETATM 3483 O O     . HOH J 4 .   ? -106.589 52.954 48.440 1.00 71.19  ? 141 HOH C O     1 
HETATM 3484 O O     . HOH J 4 .   ? -83.389  73.416 46.877 1.00 26.43  ? 142 HOH C O     1 
HETATM 3485 O O     . HOH J 4 .   ? -93.256  37.726 55.347 1.00 39.96  ? 143 HOH C O     1 
HETATM 3486 O O     . HOH J 4 .   ? -99.516  37.766 56.446 1.00 47.62  ? 144 HOH C O     1 
HETATM 3487 O O     . HOH J 4 .   ? -86.458  63.135 50.843 1.00 50.29  ? 145 HOH C O     1 
HETATM 3488 O O     . HOH J 4 .   ? -94.664  37.367 48.338 1.00 78.22  ? 146 HOH C O     1 
HETATM 3489 O O     . HOH J 4 .   ? -80.766  54.171 55.112 1.00 77.39  ? 147 HOH C O     1 
HETATM 3490 O O     . HOH J 4 .   ? -105.378 38.639 51.244 1.00 86.57  ? 148 HOH C O     1 
HETATM 3491 O O     . HOH J 4 .   ? -97.097  34.401 46.452 1.00 51.93  ? 149 HOH C O     1 
HETATM 3492 O O     . HOH J 4 .   ? -91.194  38.691 52.564 1.00 69.05  ? 150 HOH C O     1 
HETATM 3493 O O     . HOH J 4 .   ? -82.059  64.146 49.300 1.00 90.92  ? 151 HOH C O     1 
HETATM 3494 O O     . HOH J 4 .   ? -83.599  46.095 44.259 1.00 52.73  ? 152 HOH C O     1 
HETATM 3495 O O     . HOH J 4 .   ? -97.627  35.483 39.750 1.00 80.34  ? 153 HOH C O     1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   C   1   1   1   C   C   R . n 
A 1 2   C   2   2   2   C   C   R . n 
A 1 3   A   3   3   3   A   A   R . n 
A 1 4   C   4   4   4   C   C   R . n 
A 1 5   A   5   5   5   A   A   R . n 
A 1 6   G   6   6   6   G   G   R . n 
A 1 7   U   7   7   7   U   U   R . n 
A 1 8   C   8   8   8   C   C   R . n 
A 1 9   A   9   9   9   A   A   R . n 
A 1 10  C   10  10  10  C   C   R . n 
A 1 11  U   11  11  11  U   U   R . n 
A 1 12  G   12  12  12  G   G   R . n 
A 1 13  G   13  13  13  G   G   R . n 
A 1 14  G   14  14  14  G   G   R . n 
B 2 1   C   1   4   4   C   C   S . n 
B 2 2   A   2   5   5   A   A   S . n 
B 2 3   G   3   6   6   G   G   S . n 
B 2 4   U   4   7   7   U   U   S . n 
B 2 5   C   5   8   8   C   C   S . n 
B 2 6   A   6   9   9   A   A   S . n 
B 2 7   C   7   10  10  C   C   S . n 
B 2 8   U   8   11  11  U   U   S . n 
B 2 9   G   9   12  12  G   G   S . n 
B 2 10  G   10  13  13  G   G   S . n 
C 3 1   ALA 1   1   1   ALA ALA A . n 
C 3 2   SER 2   2   2   SER SER A . n 
C 3 3   ASN 3   3   3   ASN ASN A . n 
C 3 4   PHE 4   4   4   PHE PHE A . n 
C 3 5   THR 5   5   5   THR THR A . n 
C 3 6   GLN 6   6   6   GLN GLN A . n 
C 3 7   PHE 7   7   7   PHE PHE A . n 
C 3 8   VAL 8   8   8   VAL VAL A . n 
C 3 9   LEU 9   9   9   LEU LEU A . n 
C 3 10  VAL 10  10  10  VAL VAL A . n 
C 3 11  ASP 11  11  11  ASP ASP A . n 
C 3 12  ASN 12  12  12  ASN ASN A . n 
C 3 13  GLY 13  13  13  GLY GLY A . n 
C 3 14  GLY 14  14  14  GLY GLY A . n 
C 3 15  THR 15  15  15  THR THR A . n 
C 3 16  GLY 16  16  16  GLY GLY A . n 
C 3 17  ASP 17  17  17  ASP ASP A . n 
C 3 18  VAL 18  18  18  VAL VAL A . n 
C 3 19  THR 19  19  19  THR THR A . n 
C 3 20  VAL 20  20  20  VAL VAL A . n 
C 3 21  ALA 21  21  21  ALA ALA A . n 
C 3 22  PRO 22  22  22  PRO PRO A . n 
C 3 23  SER 23  23  23  SER SER A . n 
C 3 24  ASN 24  24  24  ASN ASN A . n 
C 3 25  PHE 25  25  25  PHE PHE A . n 
C 3 26  ALA 26  26  26  ALA ALA A . n 
C 3 27  ASN 27  27  27  ASN ASN A . n 
C 3 28  GLY 28  28  28  GLY GLY A . n 
C 3 29  VAL 29  29  29  VAL VAL A . n 
C 3 30  ALA 30  30  30  ALA ALA A . n 
C 3 31  GLU 31  31  31  GLU GLU A . n 
C 3 32  TRP 32  32  32  TRP TRP A . n 
C 3 33  ILE 33  33  33  ILE ILE A . n 
C 3 34  SER 34  34  34  SER SER A . n 
C 3 35  SER 35  35  35  SER SER A . n 
C 3 36  ASN 36  36  36  ASN ASN A . n 
C 3 37  SER 37  37  37  SER SER A . n 
C 3 38  ARG 38  38  38  ARG ARG A . n 
C 3 39  SER 39  39  39  SER SER A . n 
C 3 40  GLN 40  40  40  GLN GLN A . n 
C 3 41  ALA 41  41  41  ALA ALA A . n 
C 3 42  TYR 42  42  42  TYR TYR A . n 
C 3 43  LYS 43  43  43  LYS LYS A . n 
C 3 44  VAL 44  44  44  VAL VAL A . n 
C 3 45  THR 45  45  45  THR THR A . n 
C 3 46  CYS 46  46  46  CYS CYS A . n 
C 3 47  SER 47  47  47  SER SER A . n 
C 3 48  VAL 48  48  48  VAL VAL A . n 
C 3 49  ARG 49  49  49  ARG ARG A . n 
C 3 50  GLN 50  50  50  GLN GLN A . n 
C 3 51  SER 51  51  51  SER SER A . n 
C 3 52  SER 52  52  52  SER SER A . n 
C 3 53  ALA 53  53  53  ALA ALA A . n 
C 3 54  GLN 54  54  54  GLN GLN A . n 
C 3 55  ASN 55  55  55  ASN ASN A . n 
C 3 56  ARG 56  56  56  ARG ARG A . n 
C 3 57  LYS 57  57  57  LYS LYS A . n 
C 3 58  TYR 58  58  58  TYR TYR A . n 
C 3 59  THR 59  59  59  THR THR A . n 
C 3 60  ILE 60  60  60  ILE ILE A . n 
C 3 61  LYS 61  61  61  LYS LYS A . n 
C 3 62  VAL 62  62  62  VAL VAL A . n 
C 3 63  GLU 63  63  63  GLU GLU A . n 
C 3 64  VAL 64  64  64  VAL VAL A . n 
C 3 65  PRO 65  65  65  PRO PRO A . n 
C 3 66  LYS 66  66  66  LYS LYS A . n 
C 3 67  VAL 67  67  67  VAL VAL A . n 
C 3 68  ALA 68  68  68  ALA ALA A . n 
C 3 69  THR 69  69  69  THR THR A . n 
C 3 70  GLN 70  70  70  GLN GLN A . n 
C 3 71  THR 71  71  71  THR THR A . n 
C 3 72  VAL 72  72  72  VAL VAL A . n 
C 3 73  GLY 73  73  73  GLY GLY A . n 
C 3 74  GLY 74  74  74  GLY GLY A . n 
C 3 75  VAL 75  75  75  VAL VAL A . n 
C 3 76  GLU 76  76  76  GLU GLU A . n 
C 3 77  LEU 77  77  77  LEU LEU A . n 
C 3 78  PRO 78  78  78  PRO PRO A . n 
C 3 79  VAL 79  79  79  VAL VAL A . n 
C 3 80  ALA 80  80  80  ALA ALA A . n 
C 3 81  ALA 81  81  81  ALA ALA A . n 
C 3 82  TRP 82  82  82  TRP TRP A . n 
C 3 83  ARG 83  83  83  ARG ARG A . n 
C 3 84  SER 84  84  84  SER SER A . n 
C 3 85  TYR 85  85  85  TYR TYR A . n 
C 3 86  LEU 86  86  86  LEU LEU A . n 
C 3 87  ASN 87  87  87  ASN ASN A . n 
C 3 88  MET 88  88  88  MET MET A . n 
C 3 89  GLU 89  89  89  GLU GLU A . n 
C 3 90  LEU 90  90  90  LEU LEU A . n 
C 3 91  THR 91  91  91  THR THR A . n 
C 3 92  ILE 92  92  92  ILE ILE A . n 
C 3 93  PRO 93  93  93  PRO PRO A . n 
C 3 94  ILE 94  94  94  ILE ILE A . n 
C 3 95  PHE 95  95  95  PHE PHE A . n 
C 3 96  ALA 96  96  96  ALA ALA A . n 
C 3 97  THR 97  97  97  THR THR A . n 
C 3 98  ASN 98  98  98  ASN ASN A . n 
C 3 99  SER 99  99  99  SER SER A . n 
C 3 100 ASP 100 100 100 ASP ASP A . n 
C 3 101 CYS 101 101 101 CYS CYS A . n 
C 3 102 GLU 102 102 102 GLU GLU A . n 
C 3 103 LEU 103 103 103 LEU LEU A . n 
C 3 104 ILE 104 104 104 ILE ILE A . n 
C 3 105 VAL 105 105 105 VAL VAL A . n 
C 3 106 LYS 106 106 106 LYS LYS A . n 
C 3 107 ALA 107 107 107 ALA ALA A . n 
C 3 108 MET 108 108 108 MET MET A . n 
C 3 109 GLN 109 109 109 GLN GLN A . n 
C 3 110 GLY 110 110 110 GLY GLY A . n 
C 3 111 LEU 111 111 111 LEU LEU A . n 
C 3 112 LEU 112 112 112 LEU LEU A . n 
C 3 113 LYS 113 113 113 LYS LYS A . n 
C 3 114 ASP 114 114 114 ASP ASP A . n 
C 3 115 GLY 115 115 115 GLY GLY A . n 
C 3 116 ASN 116 116 116 ASN ASN A . n 
C 3 117 PRO 117 117 117 PRO PRO A . n 
C 3 118 ILE 118 118 118 ILE ILE A . n 
C 3 119 PRO 119 119 119 PRO PRO A . n 
C 3 120 SER 120 120 120 SER SER A . n 
C 3 121 ALA 121 121 121 ALA ALA A . n 
C 3 122 ILE 122 122 122 ILE ILE A . n 
C 3 123 ALA 123 123 123 ALA ALA A . n 
C 3 124 ALA 124 124 124 ALA ALA A . n 
C 3 125 ASN 125 125 125 ASN ASN A . n 
C 3 126 SER 126 126 126 SER SER A . n 
C 3 127 GLY 127 127 127 GLY GLY A . n 
C 3 128 ILE 128 128 128 ILE ILE A . n 
C 3 129 TYR 129 129 129 TYR TYR A . n 
D 3 1   ALA 1   1   1   ALA ALA B . n 
D 3 2   SER 2   2   2   SER SER B . n 
D 3 3   ASN 3   3   3   ASN ASN B . n 
D 3 4   PHE 4   4   4   PHE PHE B . n 
D 3 5   THR 5   5   5   THR THR B . n 
D 3 6   GLN 6   6   6   GLN GLN B . n 
D 3 7   PHE 7   7   7   PHE PHE B . n 
D 3 8   VAL 8   8   8   VAL VAL B . n 
D 3 9   LEU 9   9   9   LEU LEU B . n 
D 3 10  VAL 10  10  10  VAL VAL B . n 
D 3 11  ASP 11  11  11  ASP ASP B . n 
D 3 12  ASN 12  12  12  ASN ASN B . n 
D 3 13  GLY 13  13  13  GLY GLY B . n 
D 3 14  GLY 14  14  14  GLY GLY B . n 
D 3 15  THR 15  15  15  THR THR B . n 
D 3 16  GLY 16  16  16  GLY GLY B . n 
D 3 17  ASP 17  17  17  ASP ASP B . n 
D 3 18  VAL 18  18  18  VAL VAL B . n 
D 3 19  THR 19  19  19  THR THR B . n 
D 3 20  VAL 20  20  20  VAL VAL B . n 
D 3 21  ALA 21  21  21  ALA ALA B . n 
D 3 22  PRO 22  22  22  PRO PRO B . n 
D 3 23  SER 23  23  23  SER SER B . n 
D 3 24  ASN 24  24  24  ASN ASN B . n 
D 3 25  PHE 25  25  25  PHE PHE B . n 
D 3 26  ALA 26  26  26  ALA ALA B . n 
D 3 27  ASN 27  27  27  ASN ASN B . n 
D 3 28  GLY 28  28  28  GLY GLY B . n 
D 3 29  VAL 29  29  29  VAL VAL B . n 
D 3 30  ALA 30  30  30  ALA ALA B . n 
D 3 31  GLU 31  31  31  GLU GLU B . n 
D 3 32  TRP 32  32  32  TRP TRP B . n 
D 3 33  ILE 33  33  33  ILE ILE B . n 
D 3 34  SER 34  34  34  SER SER B . n 
D 3 35  SER 35  35  35  SER SER B . n 
D 3 36  ASN 36  36  36  ASN ASN B . n 
D 3 37  SER 37  37  37  SER SER B . n 
D 3 38  ARG 38  38  38  ARG ARG B . n 
D 3 39  SER 39  39  39  SER SER B . n 
D 3 40  GLN 40  40  40  GLN GLN B . n 
D 3 41  ALA 41  41  41  ALA ALA B . n 
D 3 42  TYR 42  42  42  TYR TYR B . n 
D 3 43  LYS 43  43  43  LYS LYS B . n 
D 3 44  VAL 44  44  44  VAL VAL B . n 
D 3 45  THR 45  45  45  THR THR B . n 
D 3 46  CYS 46  46  46  CYS CYS B . n 
D 3 47  SER 47  47  47  SER SER B . n 
D 3 48  VAL 48  48  48  VAL VAL B . n 
D 3 49  ARG 49  49  49  ARG ARG B . n 
D 3 50  GLN 50  50  50  GLN GLN B . n 
D 3 51  SER 51  51  51  SER SER B . n 
D 3 52  SER 52  52  52  SER SER B . n 
D 3 53  ALA 53  53  53  ALA ALA B . n 
D 3 54  GLN 54  54  54  GLN GLN B . n 
D 3 55  ASN 55  55  55  ASN ASN B . n 
D 3 56  ARG 56  56  56  ARG ARG B . n 
D 3 57  LYS 57  57  57  LYS LYS B . n 
D 3 58  TYR 58  58  58  TYR TYR B . n 
D 3 59  THR 59  59  59  THR THR B . n 
D 3 60  ILE 60  60  60  ILE ILE B . n 
D 3 61  LYS 61  61  61  LYS LYS B . n 
D 3 62  VAL 62  62  62  VAL VAL B . n 
D 3 63  GLU 63  63  63  GLU GLU B . n 
D 3 64  VAL 64  64  64  VAL VAL B . n 
D 3 65  PRO 65  65  65  PRO PRO B . n 
D 3 66  LYS 66  66  66  LYS LYS B . n 
D 3 67  VAL 67  67  67  VAL VAL B . n 
D 3 68  ALA 68  68  68  ALA ALA B . n 
D 3 69  THR 69  69  69  THR THR B . n 
D 3 70  GLN 70  70  70  GLN GLN B . n 
D 3 71  THR 71  71  71  THR THR B . n 
D 3 72  VAL 72  72  72  VAL VAL B . n 
D 3 73  GLY 73  73  73  GLY GLY B . n 
D 3 74  GLY 74  74  74  GLY GLY B . n 
D 3 75  VAL 75  75  75  VAL VAL B . n 
D 3 76  GLU 76  76  76  GLU GLU B . n 
D 3 77  LEU 77  77  77  LEU LEU B . n 
D 3 78  PRO 78  78  78  PRO PRO B . n 
D 3 79  VAL 79  79  79  VAL VAL B . n 
D 3 80  ALA 80  80  80  ALA ALA B . n 
D 3 81  ALA 81  81  81  ALA ALA B . n 
D 3 82  TRP 82  82  82  TRP TRP B . n 
D 3 83  ARG 83  83  83  ARG ARG B . n 
D 3 84  SER 84  84  84  SER SER B . n 
D 3 85  TYR 85  85  85  TYR TYR B . n 
D 3 86  LEU 86  86  86  LEU LEU B . n 
D 3 87  ASN 87  87  87  ASN ASN B . n 
D 3 88  MET 88  88  88  MET MET B . n 
D 3 89  GLU 89  89  89  GLU GLU B . n 
D 3 90  LEU 90  90  90  LEU LEU B . n 
D 3 91  THR 91  91  91  THR THR B . n 
D 3 92  ILE 92  92  92  ILE ILE B . n 
D 3 93  PRO 93  93  93  PRO PRO B . n 
D 3 94  ILE 94  94  94  ILE ILE B . n 
D 3 95  PHE 95  95  95  PHE PHE B . n 
D 3 96  ALA 96  96  96  ALA ALA B . n 
D 3 97  THR 97  97  97  THR THR B . n 
D 3 98  ASN 98  98  98  ASN ASN B . n 
D 3 99  SER 99  99  99  SER SER B . n 
D 3 100 ASP 100 100 100 ASP ASP B . n 
D 3 101 CYS 101 101 101 CYS CYS B . n 
D 3 102 GLU 102 102 102 GLU GLU B . n 
D 3 103 LEU 103 103 103 LEU LEU B . n 
D 3 104 ILE 104 104 104 ILE ILE B . n 
D 3 105 VAL 105 105 105 VAL VAL B . n 
D 3 106 LYS 106 106 106 LYS LYS B . n 
D 3 107 ALA 107 107 107 ALA ALA B . n 
D 3 108 MET 108 108 108 MET MET B . n 
D 3 109 GLN 109 109 109 GLN GLN B . n 
D 3 110 GLY 110 110 110 GLY GLY B . n 
D 3 111 LEU 111 111 111 LEU LEU B . n 
D 3 112 LEU 112 112 112 LEU LEU B . n 
D 3 113 LYS 113 113 113 LYS LYS B . n 
D 3 114 ASP 114 114 114 ASP ASP B . n 
D 3 115 GLY 115 115 115 GLY GLY B . n 
D 3 116 ASN 116 116 116 ASN ASN B . n 
D 3 117 PRO 117 117 117 PRO PRO B . n 
D 3 118 ILE 118 118 118 ILE ILE B . n 
D 3 119 PRO 119 119 119 PRO PRO B . n 
D 3 120 SER 120 120 120 SER SER B . n 
D 3 121 ALA 121 121 121 ALA ALA B . n 
D 3 122 ILE 122 122 122 ILE ILE B . n 
D 3 123 ALA 123 123 123 ALA ALA B . n 
D 3 124 ALA 124 124 124 ALA ALA B . n 
D 3 125 ASN 125 125 125 ASN ASN B . n 
D 3 126 SER 126 126 126 SER SER B . n 
D 3 127 GLY 127 127 127 GLY GLY B . n 
D 3 128 ILE 128 128 128 ILE ILE B . n 
D 3 129 TYR 129 129 129 TYR TYR B . n 
E 3 1   ALA 1   1   1   ALA ALA C . n 
E 3 2   SER 2   2   2   SER SER C . n 
E 3 3   ASN 3   3   3   ASN ASN C . n 
E 3 4   PHE 4   4   4   PHE PHE C . n 
E 3 5   THR 5   5   5   THR THR C . n 
E 3 6   GLN 6   6   6   GLN GLN C . n 
E 3 7   PHE 7   7   7   PHE PHE C . n 
E 3 8   VAL 8   8   8   VAL VAL C . n 
E 3 9   LEU 9   9   9   LEU LEU C . n 
E 3 10  VAL 10  10  10  VAL VAL C . n 
E 3 11  ASP 11  11  11  ASP ASP C . n 
E 3 12  ASN 12  12  12  ASN ASN C . n 
E 3 13  GLY 13  13  13  GLY GLY C . n 
E 3 14  GLY 14  14  14  GLY GLY C . n 
E 3 15  THR 15  15  15  THR THR C . n 
E 3 16  GLY 16  16  16  GLY GLY C . n 
E 3 17  ASP 17  17  17  ASP ASP C . n 
E 3 18  VAL 18  18  18  VAL VAL C . n 
E 3 19  THR 19  19  19  THR THR C . n 
E 3 20  VAL 20  20  20  VAL VAL C . n 
E 3 21  ALA 21  21  21  ALA ALA C . n 
E 3 22  PRO 22  22  22  PRO PRO C . n 
E 3 23  SER 23  23  23  SER SER C . n 
E 3 24  ASN 24  24  24  ASN ASN C . n 
E 3 25  PHE 25  25  25  PHE PHE C . n 
E 3 26  ALA 26  26  26  ALA ALA C . n 
E 3 27  ASN 27  27  27  ASN ASN C . n 
E 3 28  GLY 28  28  28  GLY GLY C . n 
E 3 29  VAL 29  29  29  VAL VAL C . n 
E 3 30  ALA 30  30  30  ALA ALA C . n 
E 3 31  GLU 31  31  31  GLU GLU C . n 
E 3 32  TRP 32  32  32  TRP TRP C . n 
E 3 33  ILE 33  33  33  ILE ILE C . n 
E 3 34  SER 34  34  34  SER SER C . n 
E 3 35  SER 35  35  35  SER SER C . n 
E 3 36  ASN 36  36  36  ASN ASN C . n 
E 3 37  SER 37  37  37  SER SER C . n 
E 3 38  ARG 38  38  38  ARG ARG C . n 
E 3 39  SER 39  39  39  SER SER C . n 
E 3 40  GLN 40  40  40  GLN GLN C . n 
E 3 41  ALA 41  41  41  ALA ALA C . n 
E 3 42  TYR 42  42  42  TYR TYR C . n 
E 3 43  LYS 43  43  43  LYS LYS C . n 
E 3 44  VAL 44  44  44  VAL VAL C . n 
E 3 45  THR 45  45  45  THR THR C . n 
E 3 46  CYS 46  46  46  CYS CYS C . n 
E 3 47  SER 47  47  47  SER SER C . n 
E 3 48  VAL 48  48  48  VAL VAL C . n 
E 3 49  ARG 49  49  49  ARG ARG C . n 
E 3 50  GLN 50  50  50  GLN GLN C . n 
E 3 51  SER 51  51  51  SER SER C . n 
E 3 52  SER 52  52  52  SER SER C . n 
E 3 53  ALA 53  53  53  ALA ALA C . n 
E 3 54  GLN 54  54  54  GLN GLN C . n 
E 3 55  ASN 55  55  55  ASN ASN C . n 
E 3 56  ARG 56  56  56  ARG ARG C . n 
E 3 57  LYS 57  57  57  LYS LYS C . n 
E 3 58  TYR 58  58  58  TYR TYR C . n 
E 3 59  THR 59  59  59  THR THR C . n 
E 3 60  ILE 60  60  60  ILE ILE C . n 
E 3 61  LYS 61  61  61  LYS LYS C . n 
E 3 62  VAL 62  62  62  VAL VAL C . n 
E 3 63  GLU 63  63  63  GLU GLU C . n 
E 3 64  VAL 64  64  64  VAL VAL C . n 
E 3 65  PRO 65  65  65  PRO PRO C . n 
E 3 66  LYS 66  66  66  LYS LYS C . n 
E 3 67  VAL 67  67  67  VAL VAL C . n 
E 3 68  ALA 68  68  68  ALA ALA C . n 
E 3 69  THR 69  69  69  THR THR C . n 
E 3 70  GLN 70  70  70  GLN GLN C . n 
E 3 71  THR 71  71  71  THR THR C . n 
E 3 72  VAL 72  72  72  VAL VAL C . n 
E 3 73  GLY 73  73  73  GLY GLY C . n 
E 3 74  GLY 74  74  74  GLY GLY C . n 
E 3 75  VAL 75  75  75  VAL VAL C . n 
E 3 76  GLU 76  76  76  GLU GLU C . n 
E 3 77  LEU 77  77  77  LEU LEU C . n 
E 3 78  PRO 78  78  78  PRO PRO C . n 
E 3 79  VAL 79  79  79  VAL VAL C . n 
E 3 80  ALA 80  80  80  ALA ALA C . n 
E 3 81  ALA 81  81  81  ALA ALA C . n 
E 3 82  TRP 82  82  82  TRP TRP C . n 
E 3 83  ARG 83  83  83  ARG ARG C . n 
E 3 84  SER 84  84  84  SER SER C . n 
E 3 85  TYR 85  85  85  TYR TYR C . n 
E 3 86  LEU 86  86  86  LEU LEU C . n 
E 3 87  ASN 87  87  87  ASN ASN C . n 
E 3 88  MET 88  88  88  MET MET C . n 
E 3 89  GLU 89  89  89  GLU GLU C . n 
E 3 90  LEU 90  90  90  LEU LEU C . n 
E 3 91  THR 91  91  91  THR THR C . n 
E 3 92  ILE 92  92  92  ILE ILE C . n 
E 3 93  PRO 93  93  93  PRO PRO C . n 
E 3 94  ILE 94  94  94  ILE ILE C . n 
E 3 95  PHE 95  95  95  PHE PHE C . n 
E 3 96  ALA 96  96  96  ALA ALA C . n 
E 3 97  THR 97  97  97  THR THR C . n 
E 3 98  ASN 98  98  98  ASN ASN C . n 
E 3 99  SER 99  99  99  SER SER C . n 
E 3 100 ASP 100 100 100 ASP ASP C . n 
E 3 101 CYS 101 101 101 CYS CYS C . n 
E 3 102 GLU 102 102 102 GLU GLU C . n 
E 3 103 LEU 103 103 103 LEU LEU C . n 
E 3 104 ILE 104 104 104 ILE ILE C . n 
E 3 105 VAL 105 105 105 VAL VAL C . n 
E 3 106 LYS 106 106 106 LYS LYS C . n 
E 3 107 ALA 107 107 107 ALA ALA C . n 
E 3 108 MET 108 108 108 MET MET C . n 
E 3 109 GLN 109 109 109 GLN GLN C . n 
E 3 110 GLY 110 110 110 GLY GLY C . n 
E 3 111 LEU 111 111 111 LEU LEU C . n 
E 3 112 LEU 112 112 112 LEU LEU C . n 
E 3 113 LYS 113 113 113 LYS LYS C . n 
E 3 114 ASP 114 114 114 ASP ASP C . n 
E 3 115 GLY 115 115 115 GLY GLY C . n 
E 3 116 ASN 116 116 116 ASN ASN C . n 
E 3 117 PRO 117 117 117 PRO PRO C . n 
E 3 118 ILE 118 118 118 ILE ILE C . n 
E 3 119 PRO 119 119 119 PRO PRO C . n 
E 3 120 SER 120 120 120 SER SER C . n 
E 3 121 ALA 121 121 121 ALA ALA C . n 
E 3 122 ILE 122 122 122 ILE ILE C . n 
E 3 123 ALA 123 123 123 ALA ALA C . n 
E 3 124 ALA 124 124 124 ALA ALA C . n 
E 3 125 ASN 125 125 125 ASN ASN C . n 
E 3 126 SER 126 126 126 SER SER C . n 
E 3 127 GLY 127 127 127 GLY GLY C . n 
E 3 128 ILE 128 128 128 ILE ILE C . n 
E 3 129 TYR 129 129 129 TYR TYR C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
F 4 HOH 1  85  85 HOH HOH R . 
G 4 HOH 1  86  86 HOH HOH S . 
H 4 HOH 1  130 1  HOH HOH A . 
H 4 HOH 2  131 2  HOH HOH A . 
H 4 HOH 3  132 3  HOH HOH A . 
H 4 HOH 4  133 4  HOH HOH A . 
H 4 HOH 5  134 5  HOH HOH A . 
H 4 HOH 6  135 6  HOH HOH A . 
H 4 HOH 7  136 7  HOH HOH A . 
H 4 HOH 8  137 8  HOH HOH A . 
H 4 HOH 9  138 9  HOH HOH A . 
H 4 HOH 10 139 10 HOH HOH A . 
H 4 HOH 11 140 11 HOH HOH A . 
H 4 HOH 12 141 12 HOH HOH A . 
H 4 HOH 13 142 13 HOH HOH A . 
H 4 HOH 14 143 14 HOH HOH A . 
H 4 HOH 15 144 15 HOH HOH A . 
H 4 HOH 16 145 16 HOH HOH A . 
H 4 HOH 17 146 17 HOH HOH A . 
H 4 HOH 18 147 18 HOH HOH A . 
H 4 HOH 19 148 19 HOH HOH A . 
H 4 HOH 20 149 20 HOH HOH A . 
H 4 HOH 21 150 21 HOH HOH A . 
H 4 HOH 22 151 22 HOH HOH A . 
H 4 HOH 23 152 23 HOH HOH A . 
H 4 HOH 24 153 24 HOH HOH A . 
I 4 HOH 1  130 25 HOH HOH B . 
I 4 HOH 2  131 26 HOH HOH B . 
I 4 HOH 3  132 27 HOH HOH B . 
I 4 HOH 4  133 28 HOH HOH B . 
I 4 HOH 5  134 29 HOH HOH B . 
I 4 HOH 6  135 30 HOH HOH B . 
I 4 HOH 7  136 31 HOH HOH B . 
I 4 HOH 8  137 32 HOH HOH B . 
I 4 HOH 9  138 33 HOH HOH B . 
I 4 HOH 10 139 34 HOH HOH B . 
I 4 HOH 11 140 35 HOH HOH B . 
I 4 HOH 12 141 36 HOH HOH B . 
I 4 HOH 13 142 37 HOH HOH B . 
I 4 HOH 14 143 38 HOH HOH B . 
I 4 HOH 15 144 39 HOH HOH B . 
I 4 HOH 16 145 40 HOH HOH B . 
I 4 HOH 17 146 41 HOH HOH B . 
I 4 HOH 18 147 42 HOH HOH B . 
I 4 HOH 19 148 43 HOH HOH B . 
I 4 HOH 20 149 44 HOH HOH B . 
I 4 HOH 21 150 45 HOH HOH B . 
I 4 HOH 22 151 46 HOH HOH B . 
I 4 HOH 23 152 47 HOH HOH B . 
I 4 HOH 24 153 48 HOH HOH B . 
I 4 HOH 25 154 49 HOH HOH B . 
I 4 HOH 26 155 50 HOH HOH B . 
I 4 HOH 27 156 51 HOH HOH B . 
I 4 HOH 28 157 52 HOH HOH B . 
I 4 HOH 29 158 53 HOH HOH B . 
I 4 HOH 30 159 54 HOH HOH B . 
I 4 HOH 31 160 55 HOH HOH B . 
I 4 HOH 32 161 56 HOH HOH B . 
I 4 HOH 33 162 57 HOH HOH B . 
I 4 HOH 34 163 58 HOH HOH B . 
I 4 HOH 35 164 59 HOH HOH B . 
I 4 HOH 36 165 60 HOH HOH B . 
J 4 HOH 1  130 61 HOH HOH C . 
J 4 HOH 2  131 62 HOH HOH C . 
J 4 HOH 3  132 63 HOH HOH C . 
J 4 HOH 4  133 64 HOH HOH C . 
J 4 HOH 5  134 65 HOH HOH C . 
J 4 HOH 6  135 66 HOH HOH C . 
J 4 HOH 7  136 67 HOH HOH C . 
J 4 HOH 8  137 68 HOH HOH C . 
J 4 HOH 9  138 69 HOH HOH C . 
J 4 HOH 10 139 70 HOH HOH C . 
J 4 HOH 11 140 71 HOH HOH C . 
J 4 HOH 12 141 72 HOH HOH C . 
J 4 HOH 13 142 73 HOH HOH C . 
J 4 HOH 14 143 74 HOH HOH C . 
J 4 HOH 15 144 75 HOH HOH C . 
J 4 HOH 16 145 76 HOH HOH C . 
J 4 HOH 17 146 77 HOH HOH C . 
J 4 HOH 18 147 78 HOH HOH C . 
J 4 HOH 19 148 79 HOH HOH C . 
J 4 HOH 20 149 80 HOH HOH C . 
J 4 HOH 21 150 81 HOH HOH C . 
J 4 HOH 22 151 82 HOH HOH C . 
J 4 HOH 23 152 83 HOH HOH C . 
J 4 HOH 24 153 84 HOH HOH C . 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 'complete icosahedral assembly' 300 
2 'icosahedral asymmetric unit'                  ? pentameric                      5   
3 'icosahedral pentamer'                         ? 25-meric                        25  
4 'icosahedral 23 hexamer'                       ? 30-meric                        30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric                      5   
6 'crystal asymmetric unit, crystal frame'       ? 50-meric                        50  
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E,F,G,H,I,J 
2 1                  A,B,C,D,E,F,G,H,I,J 
3 '(1-5)'            A,B,C,D,E,F,G,H,I,J 
4 '(1,2,6,10,23,24)' A,B,C,D,E,F,G,H,I,J 
5 P                  A,B,C,D,E,F,G,H,I,J 
6 '(X0)(1-10)'       A,B,C,D,E,F,G,H,I,J 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     -0.50000000 -0.86602540 0.00000079  0.00000 0.30901699  -0.17841019 0.93417252  -0.00000 
-0.80901699 0.46708650  0.35682166  -0.00000 
X0 'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000 0.00000000  1.00000000  0.00000000  0.00000  
0.00000000  0.00000000  1.00000000  0.00000  
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000 0.00000000  1.00000000  0.00000000  0.00000  
0.00000000  0.00000000  1.00000000  0.00000  
2  'point symmetry operation' ?     ?     0.50000000  -0.86602540 0.00000079  0.00000 0.64549670  0.37267830  0.66666701  0.00000  
-0.57735086 -0.33333299 0.74535569  0.00000  
3  'point symmetry operation' ?     ?     -0.30901699 -0.75576184 -0.57734958 0.00000 0.17841019  -0.64234953 0.74535688  0.00000  
-0.93417252 0.12732289  0.33333254  0.00000  
4  'point symmetry operation' ?     ?     -0.30901699 0.17841019  -0.93417252 0.00000 -0.75576184 -0.64234953 0.12732289  0.00000  
-0.57734958 0.74535688  0.33333254  0.00000  
5  'point symmetry operation' ?     ?     0.50000000  0.64549670  -0.57735086 0.00000 -0.86602540 0.37267830  -0.33333299 0.00000  
0.00000079  0.66666701  0.74535569  0.00000  
6  'point symmetry operation' ?     ?     0.30901699  -0.75576184 -0.57734958 0.00000 -0.75576184 -0.56366040 0.33333317  0.00000  
-0.57734958 0.33333317  -0.74535660 0.00000  
7  'point symmetry operation' ?     ?     0.00000000  -0.35682294 -0.93417203 0.00000 -0.93417203 0.33333401  -0.12732261 0.00000  
0.35682294  0.87267739  -0.33333401 0.00000  
8  'point symmetry operation' ?     ?     0.30901699  0.17841019  -0.93417252 0.00000 -0.17841019 0.97568389  0.12732142  0.00000  
0.93417252  0.12732142  0.33333310  0.00000  
9  'point symmetry operation' ?     ?     0.80901699  0.11026356  -0.57735037 0.00000 0.46708650  0.47568355  0.74535586  0.00000  
0.35682166  -0.87267813 0.33333345  0.00000  
10 'point symmetry operation' ?     ?     0.80901699  -0.46708650 -0.35682166 0.00000 0.11026356  -0.47568355 0.87267813  0.00000  
-0.57735037 -0.74535586 -0.33333345 0.00000  
11 'point symmetry operation' ?     ?     -0.80901699 -0.11026356 0.57735037  0.00000 -0.11026356 -0.93633960 -0.33333180 0.00000  
0.57735037  -0.33333180 0.74535660  0.00000  
12 'point symmetry operation' ?     ?     -0.80901699 0.46708650  0.35682166  0.00000 -0.46708650 -0.14235192 -0.87267756 0.00000  
-0.35682166 -0.87267756 0.33333492  0.00000  
13 'point symmetry operation' ?     ?     -0.30901699 0.75576184  0.57734958  0.00000 0.17841019  0.64234953  -0.74535688 0.00000  
-0.93417252 -0.12732289 -0.33333254 0.00000  
14 'point symmetry operation' ?     ?     0.00000000  0.35682294  0.93417203  0.00000 0.93417203  0.33333401  -0.12732261 0.00000  
-0.35682294 0.87267739  -0.33333401 0.00000  
15 'point symmetry operation' ?     ?     -0.30901699 -0.17841019 0.93417252  0.00000 0.75576184  -0.64234953 0.12732289  0.00000  
0.57734958  0.74535688  0.33333254  0.00000  
16 'point symmetry operation' ?     ?     -0.50000000 0.86602540  -0.00000079 0.00000 0.86602540  0.50000000  -0.00000137 0.00000  
-0.00000079 -0.00000137 -1.00000000 0.00000  
17 'point symmetry operation' ?     ?     0.30901699  0.75576184  0.57734958  0.00000 0.75576184  -0.56366040 0.33333317  0.00000  
0.57734958  0.33333317  -0.74535660 0.00000  
18 'point symmetry operation' ?     ?     0.30901699  -0.17841019 0.93417252  0.00000 -0.17841019 -0.97568389 -0.12732142 0.00000  
0.93417252  -0.12732142 -0.33333310 0.00000  
19 'point symmetry operation' ?     ?     -0.50000000 -0.64549670 0.57735086  0.00000 -0.64549670 -0.16666802 -0.74535614 0.00000  
0.57735086  -0.74535614 -0.33333198 0.00000  
20 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  0.00000 0.00000000  0.74535478  -0.66666802 0.00000  
0.00000000  -0.66666802 -0.74535478 0.00000  
21 'point symmetry operation' ?     ?     0.00000000  -0.35682294 -0.93417203 0.00000 0.93417203  -0.33333401 0.12732261  0.00000  
-0.35682294 -0.87267739 0.33333401  0.00000  
22 'point symmetry operation' ?     ?     0.30901699  0.17841019  -0.93417252 0.00000 0.17841019  -0.97568389 -0.12732142 0.00000  
-0.93417252 -0.12732142 -0.33333310 0.00000  
23 'point symmetry operation' ?     ?     0.80901699  0.11026356  -0.57735037 0.00000 -0.46708650 -0.47568355 -0.74535586 0.00000  
-0.35682166 0.87267813  -0.33333345 0.00000  
24 'point symmetry operation' ?     ?     0.80901699  -0.46708650 -0.35682166 0.00000 -0.11026356 0.47568355  -0.87267813 0.00000  
0.57735037  0.74535586  0.33333345  0.00000  
25 'point symmetry operation' ?     ?     0.30901699  -0.75576184 -0.57734958 0.00000 0.75576184  0.56366040  -0.33333317 0.00000  
0.57734958  -0.33333317 0.74535660  0.00000  
26 'point symmetry operation' ?     ?     0.80901699  -0.11026356 0.57735037  0.00000 0.46708650  -0.47568355 -0.74535586 0.00000  
0.35682166  0.87267813  -0.33333345 0.00000  
27 'point symmetry operation' ?     ?     0.00000000  -0.93417203 0.35682294  0.00000 0.35682294  -0.33333401 -0.87267739 0.00000  
0.93417203  0.12732261  0.33333401  0.00000  
28 'point symmetry operation' ?     ?     -0.80901699 -0.46708650 -0.35682166 0.00000 0.46708650  -0.14235192 -0.87267756 0.00000  
0.35682166  -0.87267756 0.33333492  0.00000  
29 'point symmetry operation' ?     ?     -0.50000000 0.64549670  -0.57735086 0.00000 0.64549670  -0.16666802 -0.74535614 0.00000  
-0.57735086 -0.74535614 -0.33333198 0.00000  
30 'point symmetry operation' ?     ?     0.50000000  0.86602540  -0.00000079 0.00000 0.64549670  -0.37267830 -0.66666701 0.00000  
-0.57735086 0.33333299  -0.74535569 0.00000  
31 'point symmetry operation' ?     ?     -0.50000000 0.64549670  -0.57735086 0.00000 -0.64549670 0.16666802  0.74535614  0.00000  
0.57735086  0.74535614  0.33333198  0.00000  
32 'point symmetry operation' ?     ?     0.50000000  0.86602540  -0.00000079 0.00000 -0.64549670 0.37267830  0.66666701  0.00000  
0.57735086  -0.33333299 0.74535569  0.00000  
33 'point symmetry operation' ?     ?     0.80901699  -0.11026356 0.57735037  0.00000 -0.46708650 0.47568355  0.74535586  0.00000  
-0.35682166 -0.87267813 0.33333345  0.00000  
34 'point symmetry operation' ?     ?     0.00000000  -0.93417203 0.35682294  0.00000 -0.35682294 0.33333401  0.87267739  0.00000  
-0.93417203 -0.12732261 -0.33333401 0.00000  
35 'point symmetry operation' ?     ?     -0.80901699 -0.46708650 -0.35682166 0.00000 -0.46708650 0.14235192  0.87267756  0.00000  
-0.35682166 0.87267756  -0.33333492 0.00000  
36 'point symmetry operation' ?     ?     -0.30901699 -0.17841019 0.93417252  0.00000 -0.75576184 0.64234953  -0.12732289 0.00000  
-0.57734958 -0.74535688 -0.33333254 0.00000  
37 'point symmetry operation' ?     ?     -0.80901699 -0.11026356 0.57735037  0.00000 0.11026356  0.93633960  0.33333180  0.00000  
-0.57735037 0.33333180  -0.74535660 0.00000  
38 'point symmetry operation' ?     ?     -0.80901699 0.46708650  0.35682166  0.00000 0.46708650  0.14235192  0.87267756  0.00000  
0.35682166  0.87267756  -0.33333492 0.00000  
39 'point symmetry operation' ?     ?     -0.30901699 0.75576184  0.57734958  0.00000 -0.17841019 -0.64234953 0.74535688  0.00000  
0.93417252  0.12732289  0.33333254  0.00000  
40 'point symmetry operation' ?     ?     0.00000000  0.35682294  0.93417203  0.00000 -0.93417203 -0.33333401 0.12732261  0.00000  
0.35682294  -0.87267739 0.33333401  0.00000  
41 'point symmetry operation' ?     ?     0.00000000  0.93417203  -0.35682294 0.00000 -0.35682294 -0.33333401 -0.87267739 0.00000  
-0.93417203 0.12732261  0.33333401  0.00000  
42 'point symmetry operation' ?     ?     0.80901699  0.46708650  0.35682166  0.00000 0.11026356  0.47568355  -0.87267813 0.00000  
-0.57735037 0.74535586  0.33333345  0.00000  
43 'point symmetry operation' ?     ?     0.50000000  -0.64549670 0.57735086  0.00000 0.86602540  0.37267830  -0.33333299 0.00000  
-0.00000079 0.66666701  0.74535569  0.00000  
44 'point symmetry operation' ?     ?     -0.50000000 -0.86602540 0.00000079  0.00000 0.86602540  -0.50000000 0.00000137  0.00000  
-0.00000079 0.00000137  1.00000000  0.00000  
45 'point symmetry operation' ?     ?     -0.80901699 0.11026356  -0.57735037 0.00000 0.11026356  -0.93633960 -0.33333180 0.00000  
-0.57735037 -0.33333180 0.74535660  0.00000  
46 'point symmetry operation' ?     ?     -0.50000000 -0.64549670 0.57735086  0.00000 0.64549670  0.16666802  0.74535614  0.00000  
-0.57735086 0.74535614  0.33333198  0.00000  
47 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  0.00000 0.00000000  -0.74535478 0.66666802  0.00000  
0.00000000  0.66666802  0.74535478  0.00000  
48 'point symmetry operation' ?     ?     -0.50000000 0.86602540  -0.00000079 0.00000 -0.86602540 -0.50000000 0.00000137  0.00000  
0.00000079  0.00000137  1.00000000  0.00000  
49 'point symmetry operation' ?     ?     0.30901699  0.75576184  0.57734958  0.00000 -0.75576184 0.56366040  -0.33333317 0.00000  
-0.57734958 -0.33333317 0.74535660  0.00000  
50 'point symmetry operation' ?     ?     0.30901699  -0.17841019 0.93417252  0.00000 0.17841019  0.97568389  0.12732142  0.00000  
-0.93417252 0.12732142  0.33333310  0.00000  
51 'point symmetry operation' ?     ?     -0.30901699 -0.75576184 -0.57734958 0.00000 -0.17841019 0.64234953  -0.74535688 0.00000  
0.93417252  -0.12732289 -0.33333254 0.00000  
52 'point symmetry operation' ?     ?     -0.30901699 0.17841019  -0.93417252 0.00000 0.75576184  0.64234953  -0.12732289 0.00000  
0.57734958  -0.74535688 -0.33333254 0.00000  
53 'point symmetry operation' ?     ?     0.50000000  0.64549670  -0.57735086 0.00000 0.86602540  -0.37267830 0.33333299  0.00000  
-0.00000079 -0.66666701 -0.74535569 0.00000  
54 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000 0.00000000  -1.00000000 0.00000000  0.00000  
0.00000000  0.00000000  -1.00000000 0.00000  
55 'point symmetry operation' ?     ?     0.50000000  -0.86602540 0.00000079  0.00000 -0.64549670 -0.37267830 -0.66666701 0.00000  
0.57735086  0.33333299  -0.74535569 0.00000  
56 'point symmetry operation' ?     ?     0.80901699  0.46708650  0.35682166  0.00000 -0.11026356 -0.47568355 0.87267813  0.00000  
0.57735037  -0.74535586 -0.33333345 0.00000  
57 'point symmetry operation' ?     ?     0.50000000  -0.64549670 0.57735086  0.00000 -0.86602540 -0.37267830 0.33333299  0.00000  
0.00000079  -0.66666701 -0.74535569 0.00000  
58 'point symmetry operation' ?     ?     -0.50000000 -0.86602540 0.00000079  0.00000 -0.86602540 0.50000000  -0.00000137 0.00000  
0.00000079  -0.00000137 -1.00000000 0.00000  
59 'point symmetry operation' ?     ?     -0.80901699 0.11026356  -0.57735037 0.00000 -0.11026356 0.93633960  0.33333180  0.00000  
0.57735037  0.33333180  -0.74535660 0.00000  
60 'point symmetry operation' ?     ?     0.00000000  0.93417203  -0.35682294 0.00000 0.35682294  0.33333401  0.87267739  0.00000  
0.93417203  -0.12732261 -0.33333401 0.00000  
# 
_pdbx_point_symmetry.entry_id             6MSF 
_pdbx_point_symmetry.Schoenflies_symbol   I 
_pdbx_point_symmetry.H-M_notation         532 
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 1998-07-08 
2 'Structure model' 1 1 2008-05-22 
3 'Structure model' 1 2 2011-07-13 
4 'Structure model' 1 3 2023-08-02 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Version format compliance' 
2 3 'Structure model' 'Version format compliance' 
3 4 'Structure model' 'Database references'       
4 4 'Structure model' 'Derived calculations'      
5 4 'Structure model' 'Refinement description'    
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 4 'Structure model' database_2                    
2 4 'Structure model' pdbx_initial_refinement_model 
3 4 'Structure model' pdbx_struct_oper_list         
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 4 'Structure model' '_database_2.pdbx_DOI'                      
2 4 'Structure model' '_database_2.pdbx_database_accession'       
3 4 'Structure model' '_pdbx_struct_oper_list.name'               
4 4 'Structure model' '_pdbx_struct_oper_list.symmetry_operation' 
5 4 'Structure model' '_pdbx_struct_oper_list.type'               
# 
loop_
_software.name 
_software.classification 
_software.version 
_software.citation_id 
_software.pdbx_ordinal 
CCP4   'model building' .         ? 1 
X-PLOR refinement       3.860     ? 2 
MOSFLM 'data reduction' .         ? 3 
CCP4   'data scaling'   '(SCALA)' ? 4 
CCP4   phasing          .         ? 5 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   "O5'" 
_pdbx_validate_close_contact.auth_asym_id_1   S 
_pdbx_validate_close_contact.auth_comp_id_1   C 
_pdbx_validate_close_contact.auth_seq_id_1    4 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   S 
_pdbx_validate_close_contact.auth_comp_id_2   HOH 
_pdbx_validate_close_contact.auth_seq_id_2    86 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             1.40 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 2  ? ? 175.70  128.14  
2 1 PHE A 25 ? ? -140.72 16.40   
3 1 SER A 35 ? ? -69.13  67.04   
4 1 SER B 2  ? ? 132.68  84.99   
5 1 PHE B 25 ? ? -141.92 17.36   
6 1 THR C 15 ? ? -123.10 -70.96  
7 1 ASN C 36 ? ? 75.84   -172.01 
8 1 SER C 37 ? ? -37.60  118.87  
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 0 C ARG 49 ? CZ  ? E ARG 49 CZ  
2 1 Y 0 C ARG 49 ? NH1 ? E ARG 49 NH1 
3 1 Y 0 C ARG 49 ? NH2 ? E ARG 49 NH2 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
6MSF 'a-form double helix' 
6MSF 'hairpin loop'        
6MSF 'bulge loop'          
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A C 1 1_555 A G 14 1_555 0.099  -0.148 0.037  2.444   -21.581 -0.707 1 R_C1:G14_R R 1 ? R 14 ? 19 1 
1 A C 2 1_555 A G 13 1_555 0.155  -0.052 -0.149 4.229   -8.227  1.694  2 R_C2:G13_R R 2 ? R 13 ? 19 1 
1 A C 4 1_555 A G 12 1_555 0.133  -0.058 0.248  -3.688  -3.489  1.673  3 R_C4:G12_R R 4 ? R 12 ? 19 1 
1 A A 5 1_555 A U 11 1_555 -0.022 -0.106 -0.464 -13.507 2.182   5.636  4 R_A5:U11_R R 5 ? R 11 ? 20 1 
1 A G 6 1_555 A C 10 1_555 -0.242 -0.121 0.357  -0.548  0.511   4.150  5 R_G6:C10_R R 6 ? R 10 ? 19 1 
1 B C 1 1_555 B G 9  1_555 0.129  -0.165 -0.443 -10.425 -6.251  3.237  6 S_C4:G12_S S 4 ? S 12 ? 19 1 
1 B A 2 1_555 B U 8  1_555 -0.028 -0.178 0.245  -6.264  8.615   6.986  7 S_A5:U11_S S 5 ? S 11 ? 20 1 
1 B G 3 1_555 B C 7  1_555 -0.198 -0.113 0.676  9.577   8.192   3.764  8 S_G6:C10_S S 6 ? S 10 ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A C 1 1_555 A G 14 1_555 A C 2 1_555 A G 13 1_555 -0.183 -1.668 3.380 0.133  5.148  31.583 -3.951 0.357  3.076 9.380  -0.243 
31.990 1 RR_C1C2:G13G14_RR R 1 ? R 14 ? R 2 ? R 13 ? 
1 A C 2 1_555 A G 13 1_555 A C 4 1_555 A G 12 1_555 0.148  -2.709 3.365 -2.997 6.599  29.214 -6.487 -0.860 2.675 12.835 5.829  
30.081 2 RR_C2C4:G12G13_RR R 2 ? R 13 ? R 4 ? R 12 ? 
1 A C 4 1_555 A G 12 1_555 A A 5 1_555 A U 11 1_555 -0.178 -2.037 3.407 3.699  15.691 30.481 -5.642 0.819  2.104 27.557 -6.497 
34.392 3 RR_C4A5:U11G12_RR R 4 ? R 12 ? R 5 ? R 11 ? 
1 A A 5 1_555 A U 11 1_555 A G 6 1_555 A C 10 1_555 0.294  -1.853 3.038 -3.868 -1.150 26.676 -3.698 -1.553 3.041 -2.474 8.323  
26.974 4 RR_A5G6:C10U11_RR R 5 ? R 11 ? R 6 ? R 10 ? 
1 B C 1 1_555 B G 9  1_555 B A 2 1_555 B U 8  1_555 0.002  -1.612 3.149 -3.926 10.893 31.242 -4.424 -0.582 2.447 19.410 6.995  
33.269 5 SS_C4A5:U11G12_SS S 4 ? S 12 ? S 5 ? S 11 ? 
1 B A 2 1_555 B U 8  1_555 B G 3 1_555 B C 7  1_555 0.267  -1.990 2.847 -2.014 1.950  26.836 -4.686 -1.006 2.671 4.186  4.325  
26.979 6 SS_A5G6:C10U11_SS S 5 ? S 11 ? S 6 ? S 10 ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2MS2 
_pdbx_initial_refinement_model.details          'PDB ENTRY 2MS2' 
# 
